Pattern of remyelination in the CNS
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Demyelinated axons, axons bearing native myelin sheaths, and remyelinated axons can unambiguously be distinguished on light and electron micrographs based on the thickness or absence of myelin sheaths.
“Based on the thickness (or absence) of myelin sheaths, demyelinated axons, axons bearing native myelin sheaths, and remyelinated axons on light and electron micrographs can unambiguously be distinguished54.”
From Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system (2016) · cites this paper as [54]
Cites
Principles and procedures of statistics.
Steel, R. G. D., & Torrie, J. H. (1960) · Cited by 22,178 · see citing works
Principles and Procedures of Statistics
Robinson, H. F. (1961) · Agronomy Journal · doi:10.2134/agronj1961.00021962005300050002x · Cited by 17,770 · see citing works
ULTRASTRUCTURAL STUDY OF REMYELINATION IN AN EXPERIMENTAL LESION IN ADULT CAT SPINAL CORD
Bunge, M. B., Bunge, R. P., & Ris, H. (1961) · The Journal of Cell Biology · doi:10.1083/jcb.10.1.67 · Cited by 397 · see citing works
Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone
Blakemore, W. F. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90118-4 · Cited by 207 · see citing works
Self-citationDemyelination and remyelination after acute spinal cord compression
Gledhill, R. F., Harrison, B. M., & McDonald, W. I. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90169-6 · Cited by 181 · see citing works
Blakemore, W. F. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90119-6 · Cited by 177 · see citing works
Self-citationLAMPERT, P. W. (1965) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-196507000-00001 · Cited by 165 · see citing works
Pattern of Remyelination in the CNS
Gledhill, R. F., Harrison, B. M., & McDonald, W. I. (1973) · Nature · doi:10.1038/244443a0 · Cited by 75 · see citing works
Wiśniewski, H., & Raine, C. S. (1971) · PubMed · Cited by 60 · see citing works
REMYELINATION IN THE CENTRAL NERVOUS SYSTEM AFTER CYANIDE INTOXICATION
Hirano, A., Levine, S., & Zimmerman, H. M. (1968) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-196804000-00005 · Cited by 55 · see citing works
Quantitative anatomical measurements on single isolated fibres from the cat spinal cord.
McDonald, W. I., & Ohlrich, G. D. (1971) · PubMed · Cited by 48 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Remyelination in the CNS: from biology to therapy
Franklin, R. J. M., & ffrench-Constant, C. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2480 · Cited by 1,544 · see citing works
Regenerating CNS myelin — from mechanisms to experimental medicines
Franklin, R. J. M., & ffrench-Constant, C. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.136 · Cited by 647 · see citing works
Oligodendrocytes in development, myelin generation and beyond
Kuhn, S., Gritti, L., Crooks, D., & Dombrowski, Y. (2019) · Cells · doi:10.3390/cells8111424 · Cited by 625 · see citing works
Metformin restores CNS remyelination capacity by rejuvenating aged stem cells
Neumann, B., Baror, R., Zhao, C., Segel, M., Dietmann, S., Rawji, K. S., Foerster, S., McClain, C. R., Chalut, K., van Wijngaarden, P., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.08.015 · Cited by 449 · see citing works
Behrendt, G., Baer, K., Buffo, A., Curtis, M. A., Faull, R. L., Rees, M. I., Götz, M., & Dimou, L. (2013) · Glia · doi:10.1002/glia.22432 · Cited by 219 · see citing works
Individual axons regulate the myelinating potential of single oligodendrocytes in vivo
Almeida, R. G., Czopka, T., ffrench-Constant, C., & Lyons, D. A. (2011) · Development · doi:10.1242/dev.071001 · Cited by 214 · see citing works
Mason, J. L., Langaman, C., Morell, P., Suzuki, K., & Matsushima, G. K. (2001) · Neuropathology and Applied Neurobiology · doi:10.1046/j.0305-1846.2001.00301.x · Cited by 172 · see citing works
Inhibition of CNS Remyelination by the Presence of Semaphorin 3A
Syed, Y. A., Hand, E., Möbius, W., Zhao, C., Hofer, M., Nave, K. A., & Kotter, M. R. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4930-10.2011 · Cited by 134 · see citing works
No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse
Lasiene, J., Shupe, L., Perlmutter, S., & Horner, P. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4756-07.2008 · Cited by 133 · see citing works
Oligodendrocyte progenitor cells in Alzheimer's disease: from physiology to pathology
Zou, P., Wu, C., Liu, T. C.-Y., Duan, R., & Yang, L. (2023) · Translational Neurodegeneration · doi:10.1186/s40035-023-00385-7 · Cited by 97 · see citing works
Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system
Gonzalez, G. A., Hofer, M. P., Syed, Y. A., Amaral, A. I., Rundle, J., Rahman, S., Zhao, C., & Kotter, M. R. N. (2016) · Scientific Reports · doi:10.1038/srep31599 · Cited by 82 · see citing works
Höftberger, R., Fink, S., Aboul‐Enein, F., Botond, G., Olah, J., Berki, T., Ovadi, J., Lassmann, H., Budka, H., & Kovacs, G. G. (2010) · Glia · doi:10.1002/glia.21054 · Cited by 79 · see citing works
Syed, Y. A., Baer, A., Hofer, M. P., González, G. A., Rundle, J., Myrta, S., Huang, J. K., Zhao, C., Rossner, M. J., Trotter, M. W. B., et al. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201303123 · Cited by 58 · see citing works
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells
Ettle, B., Reiprich, S., Deusser, J., Schlachetzki, J. C. M., Xiang, W., Prots, I., Masliah, E., Winner, B., Wegner, M., & Winkler, J. (2014) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2014.06.012 · Cited by 57 · see citing works
The endocannabinoid 2-AG enhances spontaneous remyelination by targeting microglia
Mecha, M., Yanguas-Casás, N., Feliú, A., Mestre, L., Carrillo-Salinas, F., Azcoitia, I., Yong, V. W., & Guaza, C. (2019) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.12.013 · Cited by 47 · see citing works
The polarity protein Scribble regulates myelination and remyelination in the central nervous system
Jarjour, A. A., Boyd, A., Dow, L. E., Holloway, R. K., Goebbels, S., Humbert, P. O., Williams, A., & ffrench-Constant, C. (2015) · PLOS Biology · doi:10.1371/journal.pbio.1002107 · Cited by 39 · see citing works
Remyelinating and neuroprotective treatments in multiple sclerosis
Stangel, M. (2004) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.13.4.331 · Cited by 22 · see citing works
- Authors
- BLAKEMORE, W. F.
- Affiliations
- University of Cambridge (GB)
- Corresponding author
- BLAKEMORE, W. F.
- Venue
- Nature
- Published
- 1974-06
- Volume
- 249
- Issue
- 5457
- Pages
- 577-578
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2080534886
- Cited by
- 182
- References
- 11
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 7 · 2022: 4 · 2021: 6 · 2020: 7 · 2019: 14 · 2018: 5 · 2017: 13 · 2016: 4 · 2015: 6 · 2014: 7 · 2013: 11 · 2012: 13
- FWCI
- 1.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Keywords
- remyelination, central nervous system, demyelination, cuprizone, myelin thickness, axon diameter, internode length, myelin ultrastructure
- MeSH terms
- Animals, Axons, Cerebellum, Chelating Agents, Cyclohexanes, Demyelinating Diseases, Hydrazones, Male, Medulla Oblongata, Microscopy, Electron, Myelin Sheath, Nerve Fibers, Myelinated, Nerve Regeneration, Neural Pathways, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
