The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Sox proteins: regulators of cell fate specification and differentiation
Abstract
Sox transcription factors play widespread roles during development; however, their versatile funtions have a relatively simple basis: the binding of a Sox protein alone to DNA does not elicit transcriptional activation or repression, but requires binding of a partner transcription factor to an adjacent site on the DNA. Thus, the activity of a Sox protein is dependent upon the identity of its partner factor and the context of the DNA sequence to which it binds. In this Primer, we provide an mechanistic overview of how Sox family proteins function, as a paradigm for transcriptional regulation of development involving multi-transcription factor complexes, and we discuss how Sox factors can thus regulate diverse processes during development.
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Citations
Cites
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Multiplex Genome Engineering Using CRISPR/Cas Systems
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The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
King, N., Westbrook, M. J., Young, S. L., Kuo, A., Abedin, M., Chapman, J., Fairclough, S., Hellsten, U., Isogai, Y., Letunic, I., et al. (2008) · Nature · doi:10.1038/nature06617 · Cited by 1,139
miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
Cheng, L.-C., Pastrana, E., Tavazoie, M., & Doetsch, F. (2009) · Nature Neuroscience · doi:10.1038/nn.2294 · Cited by 1,001
Vertebrate neurogenesis is counteracted by Sox1–3 activity
Bylund, M., Andersson, E., Novitch, B. G., & Muhr, J. (2003) · Nature Neuroscience · doi:10.1038/nn1131 · Cited by 825
Depletion of definitive gut endoderm in Sox17 -null mutant mice
Kanai-Azuma, M., Kanai, Y., Gad, J. M., Tajima, Y., Taya, C., Kurohmaru, M., Sanai, Y., Yonekawa, H., Yazaki, K., Tam, P. P. L., et al. (2002) · Development · doi:10.1242/dev.129.10.2367 · Cited by 704
The Sox9 transcription factor determines glial fate choice in the developing spinal cord
Stolt, C. C., Lommes, P., Sock, E., Chaboissier, M.-C., Schedl, A., & Wegner, M. (2003) · Genes & Development · doi:10.1101/gad.259003 · Cited by 636
Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination
Dugas, J. C., Cuellar, T. L., Scholze, A., Ason, B., Ibrahim, A., Emery, B., Zamanian, J. L., Foo, L. C., McManus, M. T., & Barres, B. A. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.027 · Cited by 577
Wood, H. B., & Episkopou, V. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00116-1 · Cited by 550 · cited 3×
“…(i.e. the nasal, lens, otic and taste bud placodes, as well as the hypophyseal placode), which are the precursors of sensory tissues, develop from the cephalic ectoderm and express Sox2 as a key regulator (Okubo et al., 2006; Schlosser et al., 2008; Uchikawa et al., 2011; Wood and Episkopou, 1999).”
BackgroundKwon, G. S., Viotti, M., & Hadjantonakis, A.-K. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.017 · Cited by 402
Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis
Kang, P., Lee, H. K., Glasgow, S. M., Finley, M., Donti, T., Gaber, Z. B., Graham, B. H., Foster, A. E., Novitch, B. G., Gronostajski, R. M., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.01.024 · Cited by 373
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Driskell, R. R., Giangreco, A., Jensen, K. B., Mulder, K. W., & Watt, F. M. (2009) · Development · doi:10.1242/dev.038620 · Cited by 331
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Sox21 promotes the progression of vertebrate neurogenesis
Sandberg, M., Källström, M., & Muhr, J. (2005) · Nature Neuroscience · doi:10.1038/nn1493 · Cited by 210
When Ets transcription factors meet their partners
Verger, A., & Duterque‐Coquillaud, M. (2002) · BioEssays · doi:10.1002/bies.10068 · Cited by 134 · cited 2×
“Introduction An emerging view of transcriptional regulation in developmental processes is that transcription factor complexes, rather than single transcription factors, play a major role (Reményi et al., 2004; Verger and Duterque-Coquillaud, 2002).”
Background
Cited by
Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity
Alexander, J. M., Guan, J., Li, B., Maliskova, L., Song, M., Shen, Y., Huang, B., Lomvardas, S., & Weiner, O. D. (2019) · eLife · doi:10.7554/elife.41769 · Cited by 346
SOX9 in cartilage development and disease
Lefebvre, V., Angelozzi, M., & Haseeb, A. (2019) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2019.07.008 · Cited by 268
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function
Dodonova, S. O., Zhu, F., Dienemann, C., Taipale, J., & Cramer, P. (2020) · Nature · doi:10.1038/s41586-020-2195-y · Cited by 265
Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts
Poncy, A., Antoniou, A., Cordi, S., Pierreux, C. E., Jacquemin, P., & Lemaigre, F. P. (2015) · Developmental Biology · doi:10.1016/j.ydbio.2015.05.012 · Cited by 125
Huang, Y.-H., Jankowski, A., Cheah, K. S. E., Prabhakar, S., & Jauch, R. (2015) · Scientific Reports · doi:10.1038/srep10398 · Cited by 86
Metadata
- Authors
- Kamachi, Y., & Kondoh, H.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2013-10-15
- Volume
- 140
- Issue
- 20
- Pages
- 4129-4144
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1989769057
- Cited by
- 572
- References
- 15
- FWCI
- 16.27
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
