The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development
Abstract
The FGF-related proto-oncogene int-2 is implicated in mouse embryogenesis, since it is expressed in specific tissues during gastrulation and neurulation (Wilkinson et al. 1988). Here, we describe the expression of this gene during subsequent fetal development, int-2 transcripts are restricted to Purkinje cells in the cerebellum and to regions of the developing retina containing early-stage differentiating cells. This high level expression is not detected in the mature cerebellum or retina. In addition, int-2 RNA is detected in the mesenchyme of the developing teeth and in sensory regions of the inner ear. This complex and dynamic pattern suggests multiple roles of this proto-oncogene during fetal development of the mouse.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Folkman, J., & Klagsbrun, M. (1987) · Science · doi:10.1126/science.2432664 · Cited by 3,491
Mesoderm induction in early Xenopus embryos by heparin-binding growth factors
Slack, J. M. W., Darlington, B. G., Heath, J. K., & Godsave, S. F. (1987) · Nature · doi:10.1038/326197a0 · Cited by 933
Kimelman, D., & Kirschner, M. (1987) · Cell · doi:10.1016/0092-8674(87)90110-3 · Cited by 874
Peptide growth factors are multifunctional
Sporn, M. B., & Roberts, A. B. (1988) · Nature · doi:10.1038/332217a0 · Cited by 818
Walicke, P., Cowan, W. M., Ueno, N., Baird, A., & Guillemin, R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.9.3012 · Cited by 733
Morrison, R. S., Sharma, A., de Vellis, J., & Bradshaw, R. A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.19.7537 · Cited by 686
Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo
Anderson, K. J., Dam, D., Lee, S., & Cotman, C. W. (1988) · Nature · doi:10.1038/332360a0 · Cited by 590
Wilkinson, D. G., Bailes, J. A., & McMahon, A. P. (1987) · Cell · doi:10.1016/0092-8674(87)90664-7 · Cited by 576
Self-citationGospodarowicz, D., Neufeld, G., & Schweigerer, L. (1986) · Cell Differentiation · doi:10.1016/0045-6039(86)90021-7 · Cited by 466
Hatten, M. E., Lynch, M., Rydel, R. E., Sanchez, J., Joseph-Silverstein, J., Moscatelli, D., & Rifkin, D. B. (1988) · Developmental Biology · doi:10.1016/0012-1606(88)90211-4 · Cited by 408
Tissue Interactions in Tooth Development
THESLEFF, I., & HURMERINTA, K. (1981) · Differentiation · doi:10.1111/j.1432-0436.1981.tb01107.x · Cited by 402
Tissue culture in neurobiology
Giacobini, E., Vernadakis, A., & Shahar, A. (1980) · Raven Press eBooks · Cited by 401
Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.
Wilkinson, D. G., Peters, G., Dickson, C., & McMahon, A. P. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02864.x · Cited by 375
Self-citationDickson, C., Smith, R., Brookes, S., & Peters, G. (1984) · Cell · doi:10.1016/0092-8674(84)90383-0 · Cited by 347
Potential oncogene product related to growth factors
DICKSON, C., & PETERS, G. (1987) · Nature · doi:10.1038/326833a0 · Cited by 342
Peters, G., Brookes, S., Smith, R., & Dickson, C. (1983) · Cell · doi:10.1016/0092-8674(83)90418-x · Cited by 320
Wilkinson, D. G., Bailes, J. A., Champion, J. E., & Mcmahon, A. P. (1987) · Development · doi:10.1242/dev.99.4.493 · Cited by 293
Self-citationEpithelial-mesenchymal interactions in development
Sawyer, R. B. (1983) · Cited by 284
Altman, J., & Bayer, S. A. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902310105 · Cited by 249
Adamson, E. D. (1987) · Development · doi:10.1242/dev.99.4.449 · Cited by 242
Moore, R., Casey, G., Brookes, S., Dixon, M., Peters, G., & Dickson, C. (1986) · The EMBO Journal · doi:10.1002/j.1460-2075.1986.tb04304.x · Cited by 225
Jakobovits, A., Shackleford, G. M., Varmus, H. E., & Martin, G. R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.20.7806 · Cited by 206
Altman, J., & Bayer, S. A. (1985) · Journal of Comparative Neurology · doi:10.1002/cne.902310103 · Cited by 202
Developmental and Evolutionary Aspects of the Neural Crest
McQuarrie, I. G. (1988) · Neurology · doi:10.1212/wnl.38.11.1817-c · Cited by 190
Growth factor superfamilies and mammalian embryogenesis
Mercola, M., & Stiles, C. D. (1988) · Development · doi:10.1242/dev.102.3.451 · Cited by 187
Jande, S. S., Tolnai, S., & Lawson, D. E. M. (1981) · Histochemistry and Cell Biology · doi:10.1007/bf00592574 · Cited by 154
Hinds, J. W., & Hinds, P. L. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901790204 · Cited by 150
Peters, G. G., Lee, A. E., & Dickson, C. (1986) · Nature · doi:10.1038/320628a0 · Cited by 134
Hinds, J. W., & Hinds, P. L. (1979) · The Journal of Comparative Neurology · doi:10.1002/cne.901870303 · Cited by 130
Smith, R., Peters, G. J., & Dickson, C. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02908.x · Cited by 129
Role of neurotrophic factors in development
Davies, A. M. (1988) · Trends in Genetics · doi:10.1016/0168-9525(88)90137-0 · Cited by 69
Four classes of mRNA are expressed from the mouse int‐2 gene, a member of the FGF gene family.
Mansour, S. L., & Martin, G. R. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03043.x · Cited by 65
Shepherd, A. M., Perkins, W. J., Green, R. J., & Clark, S. A. (1984) · Journal of Zoology · doi:10.1111/j.1469-7998.1984.tb02375.x · Cited by 16
Cited by
Receptor Specificity of the Fibroblast Growth Factor Family
Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., & Goldfarb, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.25.15292 · Cited by 1,871
FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations
Hébert, J. M., Rosenquist, T., Götz, J., & Martin, G. R. (1994) · Cell · doi:10.1016/0092-8674(94)90276-3 · Cited by 589
FGF-4 and BMP-2 have opposite effects on limb growth
Niswander, L., & Martin, G. R. (1993) · Nature · doi:10.1038/361068a0 · Cited by 377
Mcmahon, A. P., Champion, J. E., Mcmahon, J. A., & Sukhatme, V. P. (1990) · Development · doi:10.1242/dev.108.2.281 · Cited by 141
Self-citationUpadhya, D., Ogata, M., & Reneker, L. W. (2013) · Development · doi:10.1242/dev.081042 · Cited by 57
Metadata
- Authors
- Wilkinson, D. G., Bhatt, S., & Mcmahon, A. P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1989-01-01
- Volume
- 105
- Issue
- 1
- Pages
- 131-136
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2183350970
- Cited by
- 308
- References
- 33
- FWCI
- 9.67
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
