Shoot apical meristem and cotyledon formation during Arabidopsis embryogenesis: interaction among the CUP-SHAPED COTYLEDON and SHOOT MERISTEMLESS genes
Abstract
The shoot apical meristem and cotyledons of higher plants are established during embryogenesis in the apex. Redundant CUP-SHAPED COTYLEDON 1 (CUC1) and CUC2 as well as SHOOT MERISTEMLESS (STM) of Arabidopsis are required for shoot apical meristem formation and cotyledon separation. To elucidate how the apical region of the embryo is established, we investigated genetic interactions among CUC1, CUC2 and STM, as well as the expression patterns of CUC2 and STM mRNA. Expression of these genes marked the incipient shoot apical meristem as well as the boundaries of cotyledon primordia, consistent with their roles for shoot apical meristem formation and cotyledon separation. Genetic and expression analyses indicate that CUC1 and CUC2 are redundantly required for expression of STM to form the shoot apical meristem, and that STM is required for proper spatial expression of CUC2 to separate cotyledons. A model for pattern formation in the apical region of the Arabidopsis embryo is presented.
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Transcripts of LOB, CUC1, and CUC2 are detected at the boundary of the SAM and the new leaf primordium.
“Transcripts of all these genes are detected at the boundary of two tissues, the SAM and the new leaf primordium (Aida et al. 1999; Takada et al. 2001; Shuai et al. 2002).”
From Molecular analysis of the <i>LATERAL SUPPRESSOR</i> gene in <i>Arabidopsis</i> reveals a conserved control mechanism for axillary meristem formation (2003) · cites this paper as Aida et al. 1999
The pattern of LAS transcript accumulation in the axils of leaf primordia is similar to those of LOB, CUC1, and CUC2.
“The pattern of LAS transcript accumulation in the axils of leaf primordia is similar to those of the genes LATERAL ORGAN BOUNDARIES ( LOB ), CUPSHAPED COTYLEDON1 ( CUC1 ), and CUP-SHAPED COTYLEDON2 ( CUC2 ).”
From Molecular analysis of the <i>LATERAL SUPPRESSOR</i> gene in <i>Arabidopsis</i> reveals a conserved control mechanism for axillary meristem formation (2003) · cites this paper as Aida et al. 1999
CUC1 and CUC2 are required for the formation of the inter-cotyledon boundary zone and the SAM.
“Very important are the NAM/CUC genes CUC1 and CUC2, required for the formation of the inter-cotyledon boundary zone and the SAM.”
From <i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems (2016) · cites this paper as Aida et al., 1999
In dicotyledonous plant development, a boundary zone is established between the two cotyledons, which subsequently gives rise to formation of the SAM.
“In dicotyledonous plant development, a boundary zone is established between the two cotyledons, which subsequently gives rise to formation of the SAM (Aida et al., 1999).”
From <i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems (2016) · cites this paper as Aida et al., 1999
Cites
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<i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems
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- Authors
- Aida, M., Ishida, T., & Tasaka, M.
- Affiliations
- Nara Institute of Science and Technology (JP)
- Kyoto University (JP)
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1999-04-15
- Volume
- 126
- Issue
- 8
- Pages
- 1563-1570
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2118310339
- Cited by
- 557
- References
- 2
- Citations by year
- 2026: 17 · 2025: 13 · 2024: 16 · 2023: 17 · 2022: 22 · 2021: 30 · 2020: 23 · 2019: 19 · 2018: 20 · 2017: 25 · 2016: 8 · 2015: 25 · 2014: 16 · 2013: 16 · 2012: 26
- FWCI
- 21.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Development (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
- Keywords
- shoot apical meristem, CUC1, CUC2, SHOOT MERISTEMLESS, STM, Arabidopsis thaliana, embryonic development, genetic interactions, pattern formation, gene expression
- MeSH terms
- Plant Proteins, Arabidopsis, Homeodomain Proteins, Gene Expression Regulation, Developmental, Meristem, Plant Shoots, Cotyledon, Arabidopsis Proteins
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