Cited by 89Plant Molecular Biology ResearchPlant Parasitism and ResistanceDevelopmental Biology and Gene Regulation

Arabidopsis JAGGED LATERAL ORGANS Acts with ASYMMETRIC LEAVES2 to Coordinate KNOX and PIN Expression in Shoot and Root Meristems

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Rast, Madlen I., Simon, Rüdiger·2012·The Plant Cell

Abstract

Organ initiation requires the specification of a group of founder cells at the flanks of the shoot apical meristem and the creation of a functional boundary that separates the incipient primordia from the remainder of the meristem. Organ development is closely linked to the downregulation of class I KNOTTED1 LIKE HOMEOBOX (KNOX) genes and accumulation of auxin at sites of primordia initiation. Here, we show that Arabidopsis thaliana JAGGED LATERAL ORGANS (JLO), a member of the LATERAL ORGAN BOUNDARY DOMAIN (LBD) gene family, is required for coordinated organ development in shoot and floral meristems. Loss of JLO function results in ectopic expression of the KNOX genes SHOOT MERISTEMLESS and BREVIPEDICELLUS (BP), indicating that JLO acts to restrict KNOX expression. JLO acts in a trimeric protein complex with ASYMMETRIC LEAVES2 (AS2), another LBD protein, and AS1 to suppress BP expression in lateral organs. In addition to its role in KNOX regulation, we identified a role for AS2 in regulating PINFORMED (PIN) expression and auxin transport from embryogenesis onwards together with JLO. We propose that different JLO and AS2 protein complexes, possibly also comprising other LBD proteins, coordinate auxin distribution and meristem function through the regulation of KNOX and PIN expression during Arabidopsis development.

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Crossref · 10.1105/tpc.112.099978

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Authors
Rast, M. I., & Simon, R.
Affiliations
  • Institut für Entwicklungsgenetik, Heinrich-Heine-Universität, 40225 Duesseldorf, Germany
  • Heinrich Heine University Düsseldorf (DE)
Venue
The Plant Cell
Published
2012-07
Volume
24
Issue
7
Pages
2917-2933
ISSN
  • 1040-4651 (ISSN-L)
  • 1532-298X
OpenAlex
W2113083753
Cited by
89
References
50
Citations by year
2026: 3 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 11 · 2016: 5 · 2015: 12 · 2014: 8 · 2013: 12 · 2012: 1
FWCI
12.06
Type
journal article
Language
en
Open access
Locations
  • The Plant Cell (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Keywords
ASYMMETRIC LEAVES2, AS1, SHOOT MERISTEMLESS, auxin transport, auxin distribution, organ initiation, shoot apical meristem, floral meristem, root meristem, founder cells, Arabidopsis thaliana
MeSH terms
Alleles, Biological Transport, Indoleacetic Acids, Models, Molecular, Mutation, Phenotype, Repressor Proteins, Transcription Factors, Down-Regulation, Up-Regulation, Arabidopsis, Protein Structure, Tertiary, Gene Expression Regulation, Plant, Plant Roots, Meristem, Gene Dosage, Protein Interaction Mapping, Arabidopsis Proteins, Plant Components, Aerial, Seedlings, Protein Multimerization

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