The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development
Open accessAbstract
An increasing body of evidence points to significant spatio-temporal differences in early placental development between mouse and human, but a detailed comparison of placentae in these two species is missing. We set out to compare placentae from both species across gestation, with a focus on trophoblast progenitor markers. We found that CDX2 and ELF5, but not EOMES, are expressed in early post-implantation trophoblast subpopulations in both species. Genome-wide expression profiling of mouse and human placentae revealed clusters of genes with distinct co-expression patterns across gestation. Overall, there was a closer fit between patterns observed in the placentae when the inter-species comparison was restricted to human placentae through gestational week 16 (thus, excluding full-term samples), suggesting that the developmental timeline in mouse runs parallel to the first half of human placental development. In addition, we identified VGLL1 as a human-specific marker of proliferative cytotrophoblast, where it is co-expressed with the transcription factor TEAD4. As TEAD4 is involved in trophectoderm specification in the mouse, we posit a regulatory role for VGLL1 in early events during human placental development.
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Cites
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
Edgar, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.207 · Cited by 13,288
REVIGO summarizes and visualizes long lists of gene ontology terms
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ARID3A is required for mammalian placenta development
Rhee, C., Edwards, M., Dang, C., Harris, J., Brown, M., Kim, J., & Tucker, H. O. (2017) · Developmental Biology · doi:10.1016/j.ydbio.2016.12.003 · Cited by 42
Cited by
Development of the human placenta
Turco, M. Y., & Moffett, A. (2019) · Development · doi:10.1242/dev.163428 · Cited by 698
Haider, S., Meinhardt, G., Saleh, L., Kunihs, V., Gamperl, M., Kaindl, U., Ellinger, A., Burkard, T. R., Fiala, C., Pollheimer, J., et al. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.07.004 · Cited by 417
Animal models of human pregnancy and placentation: alternatives to the mouse
Carter, A. M. (2020) · Reproduction · doi:10.1530/rep-20-0354 · Cited by 130
Sex at the interface: the origin and impact of sex differences in the developing human placenta
Braun, A. E., Mitchel, O. R., Gonzalez, T. L., Sun, T., Flowers, A. E., Pisarska, M. D., & Winn, V. D. (2022) · Biology of Sex Differences · doi:10.1186/s13293-022-00459-7 · Cited by 94
Metadata
- Authors
- Soncin, F., Khater, M., To, C., Pizzo, D., Farah, O., Wakeland, A., Arul Nambi Rajan, K., Nelson, K. K., Chang, C.-W., Moretto-Zita, M., Natale, D. R., Laurent, L. C., & Parast, M. M.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2018-01-15
- Volume
- 145
- Issue
- 2
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2786428929
- Cited by
- 194
- References
- 5
- FWCI
- 17.62
- Type
- journal article
- Language
- en
- Open access
- green
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- Soncin, F., Khater, M., To, C., Pizzo, D., Farah, O., Wakeland, A., Arul Nambi Rajan, K., Nelson, K. K., Chang, C.-W., Moretto-Zita, M., Natale, D. R., Laurent, L. C., & Parast, M. M. (2018). Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. Development. https://doi.org/10.1242/dev.156273
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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