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Sustained and Shorter Bouts of Physical Activity Are Related to Cardiovascular Health
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PURPOSE: Whereas greater physical activity (PA) is known to prevent cardiovascular disease (CVD), the relative importance of performing PA in sustained bouts of activity versus shorter bouts of activity on CVD risk is not known. The objective of this study was to investigate the relationship between moderate-to-vigorous PA (MVPA), measured in bouts ≥10 and <10 min, and CVD risk factors in a well-characterized community-based sample of white adults. METHODS: We conducted a cross-sectional analysis of 2109 participants in the Third Generation Cohort of the Framingham Heart Study (mean age = 47 yr, 55% women) who underwent objective assessment of PA by accelerometry over 5-7 d. Total MVPA, MVPA done in bouts ≥10 min (MVPA(10+)), and MVPA done in bouts <10 min (MVPA(<10)) were calculated. MVPA exposures were related to individual CVD risk factors, including measures of adiposity and blood lipid and glucose levels, using linear and logistic regression. RESULTS: Total MVPA was significantly associated with higher HDL levels and with lower triglycerides, BMI, waist circumference, and Framingham risk score (P < 0.0001). MVPA(<10) showed similar statistically significant associations with these CVD risk factors (P < 0.001). Compliance with national guidelines (≥150 min of total MVPA) was significantly related to lower BMI, triglycerides, Framingham risk score, waist circumference, higher HDL, and a lower prevalence of obesity and impaired fasting glucose (P < 0.001 for all). CONCLUSIONS: Our cross-sectional observations on a large middle-age community-based sample confirm a positive association of MVPA with a healthier CVD risk factor profile and indicate that accruing PA in bouts <10 min may favorably influence cardiometabolic risk. Additional investigations are warranted to confirm our findings.
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“Although traditional recommendations [61] suggest that accumulated MVPA bouts should last ≥10 min to achieve the 30-min daily minimum, more recent studies suggest that even shorter periods of PA, accrued over time, can produce CV and metabolic health benefits [ 62 , 63 ].”
From Physical activity, cardiorespiratory fitness, and cardiovascular health: A clinical practice statement of the American Society for Preventive Cardiology Part II: Physical activity, cardiorespiratory fitness, minimum and goal intensities for exercise training, prescriptive methods, and special patient populations (2022) · cites this paper as [63]
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“MVPA10+ is a more appropriate measure of purposeful exercise [32] and therefore allows a more direct objective assessment of exercise adherence.”
From High-Intensity Interval Training as an Efficacious Alternative to Moderate-Intensity Continuous Training for Adults with Prediabetes (2015) · cites this paper as [32]
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Metadata
- Authors
- GLAZER, N. L., LYASS, A., ESLIGER, D. W., BLEASE, S. J., FREEDSON, P. S., MASSARO, J. M., MURABITO, J. M., & VASAN, R. S.
- Affiliations
- Boston University (US)
- Loughborough University (GB)
- National Heart, Lung, and Blood Institute (US)
- University of Massachusetts Amherst (US)
- ORCID
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2013-01
- Volume
- 45
- Issue
- 1
- Pages
- 109-115
- ISSN
- 0195-9131 (ISSN-L)
- PMC
- PMC4166425
- OpenAlex
- W2085039082
- Cited by
- 207
- References
- 41
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 5 · 2023: 15 · 2022: 12 · 2021: 16 · 2020: 16 · 2019: 20 · 2018: 18 · 2017: 12 · 2016: 22 · 2015: 33 · 2014: 14 · 2013: 10
- FWCI
- 18.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Loughborough University Institutional Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
- Loughborough University Research Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
- ScholarWorks@UMassAmherst (University of Massachusetts Amherst) (submittedVersion)
- Funders
- National Institutes of Health (n01hc25195-41-0-1)
- National Heart, Lung, and Blood Institute (N01‐HC25195, N01-HC-025195)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- physical activity bouts, moderate-to-vigorous physical activity, cardiovascular risk factors, cardiometabolic risk, HDL cholesterol, triglycerides, body mass index, waist circumference, Framingham risk score, impaired fasting glucose, obesity, physical activity guidelines compliance, accelerometry
- MeSH terms
- Adult, Cardiovascular Diseases, Cross-Sectional Studies, Female, Health Status Indicators, Humans, Male, Middle Aged, Risk Factors, Time Factors, Exercise, Linear Models, Logistic Models, Accelerometry
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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