The DOI matches its Crossref record; 407 of the 455 references it cites were found in a registry or an index.
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Open accessAbstract
Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes (i.e., proliferation, migration, differentiation, synaptogenesis, myelination, and apoptosis). Evidence from numerous sources demonstrates that neural development extends from the embryonic period through adolescence. In general, the sequence of events is comparable among species, although the time scales are considerably different. Developmental exposure of animals or humans to numerous agents (e.g., X-ray irradiation, methylazoxymethanol, ethanol, lead, methyl mercury, or chlorpyrifos) demonstrates that interference with one or more of these developmental processes can lead to developmental neurotoxicity. Different behavioral domains (e.g., sensory, motor, and various cognitive functions) are subserved by different brain areas. Although there are important differences between the rodent and human brain, analogous structures can be identified. Moreover, the ontogeny of specific behaviors can be used to draw inferences regarding the maturation of specific brain structures or neural circuits in rodents and primates, including humans. Furthermore, various clinical disorders in humans (e.g., schizophrenia, dyslexia, epilepsy, and autism) may also be the result of interference with normal ontogeny of developmental processes in the nervous system. Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function. This concern is compounded by the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“By the time the apical radial glial progenitors within the prefrontal subdomains start dividing asymmetrically, the number of neurons will increase rapidly and peaks between week 13 and 16 of gestation in human (E10-E15 rodents/E43-E50 primates), specifically in the dorsal telencephalon [44–47].”
From Development of prefrontal cortex (2022) · cites this paper as [47]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“This is based on developmental endpoints, since rodent exposures in early infancy (i.e., the neonatal period) mimic human 3rd trimester exposures for several organs, including the lung [50] and brain [51].”
From Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter (2021) · cites this paper as [51]
The cited source says what the claim attributes to it.
In the citing paper
“This window of exposure is critical to central nervous system development and equivalent to human 3rd trimester brain development [51].”
From Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter (2021) · cites this paper as [51]
The cited source says what the claim attributes to it.
In the citing paper
“Developmental neurotoxicity (DNT) testing is particularly critical, as chemical-induced disruptions in neurogenesis, synaptogenesis, migration, or network formation during vulnerable developmental windows can cause lifelong neurological deficits (Rice and Barone, 2000; Grandjean and Landrigan, 2014).”
From Challenges and solutions in transitioning to animal-free standards: a comprehensive analysis of components in human cell-based developmental neurotoxicity assays (2026) · cites this paper as Rice and Barone, 2000
In the citing paper
“These neurodevelopmental processes physiologically occurs during the first and second trimester of pregnancy [231].”
From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [231]
In the citing paper
“This field is especially promising for cerebellar neuropathology, in light of the prolonged developmental time window exposing cerebellar circuits to damage by environmental agents in genetically susceptible individuals not only prenatally, but also postnatally [231].”
From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [231]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Construction Of Reality In The Child
Piaget, J. (2013) · Routledge eBooks · doi:10.4324/9781315009650 · Cited by 4,608
Storage and Executive Processes in the Frontal Lobes
Smith, E. E., & Jonides, J. (1999) · Science · doi:10.1126/science.283.5408.1657 · Cited by 2,834
RECOGNITION OF THE FETAL ALCOHOL SYNDROME IN EARLY INFANCY
Jones, K., & Smith, D. (1973) · The Lancet · doi:10.1016/s0140-6736(73)91092-1 · Cited by 2,780
Mode of cell migration to the superficial layers of fetal monkey neocortex
Rakic, P. (1972) · Journal of Comparative Neurology · doi:10.1002/cne.901450105 · Cited by 2,170
Fuster, J. M. (1997) · Cited by 2,095
A framework for mesencephalic dopamine systems based on predictive Hebbian learning
Montague, P., Dayan, P., & Sejnowski, T. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-05-01936.1996 · Cited by 2,066
Increased Cortical Representation of the Fingers of the Left Hand in String Players
Elbert, T. R., Pantev, C., Wienbruch, C., Rockstroh, B. S., & Taub, E. (1995) · Science · doi:10.1126/science.270.5234.305 · Cited by 2,053
Geschwind, N. (1985) · Archives of Neurology · doi:10.1001/archneur.1985.04060060019009 · Cited by 1,773
Wiesel, T. N., & Hubel, D. H. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.6.1029 · Cited by 1,598
Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse
ANGEVINE, J. B., & SIDMAN, R. L. (1961) · Nature · doi:10.1038/192766b0 · Cited by 1,530
Cited by
Sorted by citations
Items 401–500 of 1,012
Cognitive and Behavioral Impact on Children Exposed to Opioids During Pregnancy
Larson, J. J., Graham, D. L., Singer, L. T., Beckwith, A. M., Terplan, M., Davis, J. M., Martinez, J., & Bada, H. S. (2019) · PEDIATRICS · doi:10.1542/peds.2019-0514 · Cited by 96
Zhang, Q., Lu, X.-M., Zhang, X., Sun, Y., Zhu, D., Wang, B., Zhao, R., & Zhang, Z. (2013) · Atmospheric Environment · doi:10.1016/j.atmosenv.2012.12.029 · Cited by 96
Sakamoto, M., Kaneoka, T., Murata, K., Nakai, K., Satoh, H., & Akagi, H. (2006) · Environmental Research · doi:10.1016/j.envres.2006.03.004 · Cited by 96
Garcia, S. J., Seidler, F. J., & Slotkin, T. A. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5791 · Cited by 96
Wang, Y., Zhang, Y., Ji, L., Hu, Y., Zhang, J., Wang, C., Ding, G., Chen, L., Kamijima, M., Ueyama, J., et al. (2017) · Environment International · doi:10.1016/j.envint.2017.08.010 · Cited by 95
Brain Iron Metabolism, Redox Balance and Neurological Diseases
Gao, G., You, L., Zhang, J. J., Chang, Y., & Yu, P. (2023) · Antioxidants · doi:10.3390/antiox12061289 · Cited by 95
Autophagy in acute brain injury: Feast, famine, or folly?
Smith, C. M., Chen, Y., Sullivan, M. L. G., Kochanek, P. M., & Clark, R. S. B. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.09.014 · Cited by 95
Deng, M., Hofacer, R. D., Jiang, C., Joseph, B., Hughes, E. A., Jia, B., Danzer, S. C., & Loepke, A. W. (2014) · British Journal of Anaesthesia · doi:10.1093/bja/aet469 · Cited by 95
Mitochondrial-Mediated Apoptosis in Neural Stem Cells Exposed to Manganese
Tamm, C., Sabri, F., & Ceccatelli, S. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm267 · Cited by 95
Oliphant, K., Ali, M., D’Souza, M., Hughes, P. D., Sulakhe, D., Wang, A. Z., Xie, B., Yeasin, R., Msall, M. E., Andrews, B., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1997560 · Cited by 94
Dikranian, K. T., Cohen, R. A., Donald, C. M., Pan, Y., Brakefield, D., Bayly, P. V., & Parsadanian, A. S. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.03.012 · Cited by 94
Optimizing gradient waveforms for microstructure sensitivity in diffusion-weighted MR
Drobnjak, I., Siow, B. M., & Alexander, D. C. (2010) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2010.05.017 · Cited by 94
Developmental Neurotoxicity of Organophosphates
Slotkin, T. A. (2006) · Elsevier eBooks · doi:10.1016/b978-012088523-7/50022-3 · Cited by 94
Health Impacts and Biomarkers of Prenatal Exposure to Methylmercury: Lessons from Minamata, Japan
Sakamoto, M., Tatsuta, N., Izumo, K., Phan, P. T., Loi, V. D., Yamamoto, M., 中村政明, Nakai, K., & Murata, K. (2018) · Toxics · doi:10.3390/toxics6030045 · Cited by 93
Wang, Y., Rogan, W. J., Chen, H., Chen, P., Su, P., Chen, H.-Y., & Wang, S. (2015) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2015.07.002 · Cited by 93
Narita, M., Oyabu, A., Imura, Y., Kamada, N., Yokoyama, T., Tano, K., Uchida, A., & Narita, N. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.09.001 · Cited by 93
Slotkin, T. A. (2003) · NeuroToxicology · doi:10.1016/s0161-813x(03)00050-0 · Cited by 93
Impact of low-level exposure to organophosphates on human reproduction and survival
Peiris-John, R. J., & Wickremasinghe, R. (2008) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2007.11.012 · Cited by 93
Allostasis and the developing human brain: Explicit consideration of implicit models
Ganzel, B. L., & Morris, P. (2011) · Development and Psychopathology · doi:10.1017/s0954579411000447 · Cited by 93
Residual effects of cannabis use in adolescent and adult brains — A meta-analysis of fMRI studies
Blest‐Hopley, G., Giampietro, V., & Bhattacharyya, S. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.03.008 · Cited by 93
Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism
Palma, G. D., Catalani, S., Franco, A., Brighenti, M., & Apostoli, P. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1245-6 · Cited by 93
Júlvez, J., & Grandjean, P. (2009) · Industrial Health · doi:10.2486/indhealth.47.459 · Cited by 92
Kleiber, M. L., Mantha, K., Stringer, R., & Singh, S. M. (2013) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-5-6 · Cited by 92
Dai, Q., Xu, X., Eskenazi, B., Asante, K. A., Chen, A., Fobil, J. N., Bergman, Å., Brennan, L., Sly, P. D., Nnorom, I. C., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105731 · Cited by 92
Williams, M. T., Morford, L. L., Wood, S. L., Wallace, T. L., Fukumura, M., Broening, H. W., & Vorhees, C. V. (2003) · Synapse · doi:10.1002/syn.10159 · Cited by 92
Chatterjee, D., Chatterjee‐Chakraborty, M., Rees, S., Cauchi, J., de Medeiros, C. B., & Fleming, A. S. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.069 · Cited by 92
Ding, G., Yu, J., Cui, C., Chen, L., Gao, Y., Wang, C., Zhou, Y., & Tian, Y. (2015) · Environmental Research · doi:10.1016/j.envres.2015.06.008 · Cited by 92
Identifying environmental contributions to autism: Provocative clues and false leads
Lawler, C. P., Croen, L., Grether, J. K., & de Water, J. V. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20043 · Cited by 92
Reproductive and Developmental Toxicology
Carlson, L. M., Chiang, C., Hotchkiss, A. K., Lizarraga, L. E., Luben, T., Makris, S. L., Radke, E. G., Weitekamp, C. A., & Yost, E. E. (2023) · Wiley eBooks · doi:10.1002/0471125474.tox123 · Cited by 92
Modafferi, S., Zhong, X., Kleensang, A., Murata, Y., Fagiani, F., Pamies, D., Högberg, H. T., Calabrese, V., Lachman, H. M., Härtung, T., et al. (2021) · Environmental Health Perspectives · doi:10.1289/ehp8580 · Cited by 91
Adams, J., Barone, S., LaMantia, A., Philen, R. M., Rice, D. C., SPEAR, L. P., & Susser, E. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108s3535 · Cited by 91
Self-citationMulder, K., King, D. J., & Innis, S. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0083764 · Cited by 90
Microglia toxicity in preterm brain injury
Baburamani, A. A., Supramaniam, V. G., Hagberg, H., & Mallard, C. E. (2014) · Reproductive Toxicology · doi:10.1016/j.reprotox.2014.04.002 · Cited by 90
de Córdova, F. M., Aguiar, A. S., Peres, T. V., Lopes, M. W., Gonçalves, F. M., Remor, A. P., Lopes, S. C., Pilati, C., Latini, A., Prediger, R. D., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033057 · Cited by 90
Exposure to pesticides and mental disorders in a rural population of Southern Brazil
Campos, Ÿ., da Silva, V. D. S. P., Sarpa, M., & Otero, U. B. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.06.002 · Cited by 90
Towle, P. O., Patrick, P. A., Ridgard, T., Pham, S., & Marrus, J. (2020) · Autism Research and Treatment · doi:10.1155/2020/7605876 · Cited by 90
Luque-García, L., Corrales, A., Lertxundi, A., Díaz, S., & Ibarluzea, J. M. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112599 · Cited by 91
HUANG, C., Hsu, C., Liu, S., & Lin‐Shiau, S. (2007) · Toxicology Letters · doi:10.1016/j.toxlet.2007.11.004 · Cited by 90
Garman, R. H., Fix, A. S., Jortner, B. S., Jensen, K. F., Hardisty, J. F., Cláudio, L., & Ferenc, S. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109s193 · Cited by 90
Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus
Tran, P. V., Kennedy, B. C., Lien, Y., Simmons, R. A., & Georgieff, M. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00429.2014 · Cited by 90
Hornig, M., & Lipkin, W. I. (2001) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.1028 · Cited by 90
Luecken, L. J. (2008) · Handbook of bereavement research and practice: Advances in theory and intervention. · doi:10.1037/14498-019 · Cited by 89
Physical activity and brain development
Gomes da Silva, S., & Arida, R. M. (2015) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2015.1077115 · Cited by 89
Prenatal p,p´ -DDE Exposure and Neurodevelopment among Children 3.5–5 Years of Age
Torres‐Sánchez, L., Schnaas, L., Rothenberg, S. J., Cebrián, M. E., Osorio-Valencia, E., Hernández, M. D. C., García-Hernández, R. M., & López‐Carrillo, L. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1205034 · Cited by 89
Perera, F. P., Tang, D. L., Rauh, V., Tu, Y. H., Tsai, W. Y., Becker, M., Stein, J. L., King, J., Priore, G. D., & Lederman, S. A. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10144 · Cited by 89
O’Callaghan, F., Mamun, A. A., O'Callaghan, M. J., Clavarino, A. M., Williams, G. M., Bor, W., Heussler, H., & Najman, J. M. (2010) · Early Human Development · doi:10.1016/j.earlhumdev.2010.05.020 · Cited by 89
Lin, H., Yuan, K., Li, L., Liu, S., Li, S., Hu, G., Lian, Q., & Ge, R. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph121113696 · Cited by 88
Hansen, J. B., Bilenberg, N., Timmermann, C. A. G., Jensen, R. C., Frederiksen, H. W., Andersson, A., Kyhl, H. B., & Jensen, T. K. (2021) · Environmental Health · doi:10.1186/s12940-021-00709-y · Cited by 88
Pragnya, B., Kameshwari, J. S. L., & Veeresh, B. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.04.045 · Cited by 88
Bisphenol A Impairs Synaptic Plasticity by Both Pre‐ and Postsynaptic Mechanisms
Hu, F., Li, T., Gong, H., Chen, Z., Jin, Y., Xu, G., & Wang, M. (2017) · Advanced Science · doi:10.1002/advs.201600493 · Cited by 87
Klocke, C., Allen, J. L., Sobolewski, M., Mayer-Pröschel, M., Blum, J. L., Lauterstein, D., Zelikoff, J. T., & Cory-Slechta, D. A. (2017) · Toxicological Sciences · doi:10.1093/toxsci/kfx010 · Cited by 87
Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development
Gonzalez‐Lozano, M. A., Klemmer, P., Gebuis, T., Hassan, C., van Nierop, P., van Kesteren, R. E., Smit, A. B., & Li, K. W. (2016) · Scientific Reports · doi:10.1038/srep35456 · Cited by 87
Reuben, A., Arseneault, L., Beddows, A. V., Beevers, S. D., Moffitt, T. E., Ambler, A. P., Latham, R. M., Newbury, J. B., Odgers, C. L., Schaefer, J. D., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.7508 · Cited by 89
Carstens, K. E., Freudenrich, T. M., Wallace, K., Choo, S., Carpenter, A., Smeltz, M. G., Clifton, M. S., Henderson, W. M., Richard, A. M., Patlewicz, G. Y., et al. (2023) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.2c00344 · Cited by 85
Bouayed, J., Desor, F., Rammal, H., Kiemer, A. K., Tybl, E., Schroeder, H., Rychen, G., & Soulimani, R. (2009) · Toxicology · doi:10.1016/j.tox.2009.02.010 · Cited by 87
Mitchell, E. J., Frisbie, S. H., & Sarkar, B. (2011) · Metallomics · doi:10.1039/c1mt00052g · Cited by 87
Dadvand, P., Rankin, J. M., Rushton, S. P., & Pless‐Mulloli, T. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq342 · Cited by 87
Liu, P., Wu, C., Chang, X., Qi, X., Zheng, M., & Zhou, Z. (2016) · Environmental Health Perspectives · doi:10.1289/ehp196 · Cited by 87
Harrill, J. A., Freudenrich, T., Wallace, K., Ball, K., Shafer, T. J., & Mundy, W. R. (2018) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2018.04.001 · Cited by 86
Schneider, M., & Koch, M. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.04.014 · Cited by 86
Smith, C. A., MacDonald, A. M., & Holahan, M. R. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.06.082 · Cited by 86
Bock, J., Murmu, M. S., Biala, Y., Weinstock, M., & Braun, K. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.07.048 · Cited by 86
Bolon, B. N., Garman, R. H., Jensen, K. F., Krinke, G. J., & Stuart, B. P. (2006) · Toxicologic Pathology · doi:10.1080/01926230600713269 · Cited by 86
Homberg, J. R., Kyzar, E. J., Nguyen, M., Norton, W., Pittman, J. T., Poudel, M. K., Gaikwad, S., Nakamura, S., Koshiba, M., Yamanouchi, H., et al. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.013 · Cited by 86
Ahlers‐Dannen, K. E., Karaçay, B., Fuller, L. C., Bonthius, D. J., & Dailey, M. E. (2015) · Glia · doi:10.1002/glia.22835 · Cited by 85
Doll, C. A., & Broadie, K. S. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00030 · Cited by 86
Abnormal Serotonin Levels During Perinatal Development Lead to Behavioral Deficits in Adulthood
Shah, R., Courtiol, E., Castellanos, F. X., & Teixeira, C. M. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00114 · Cited by 85
Harrill, J. A., Freudenrich, T. M., Robinette, B. L., & Mundy, W. R. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.02.013 · Cited by 85
Maternal folate status as a risk factor for autism spectrum disorders: a review of existing evidence
DeVilbiss, E. A., Gardner, R. M., Newschaffer, C. J., & Lee, B. K. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515002470 · Cited by 85
Williamson, L. L., McKenney, E. A., Holzknecht, Z. E., Belliveau, C., Rawls, J. F., Poulton, S., Parker, W., & Bilbo, S. D. (2016) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2015.07.006 · Cited by 84
Tanaka, M., Spekker, E., Szabó, Á., Polyák, H., & Vécsei, L. (2022) · Journal of Neural Transmission · doi:10.1007/s00702-022-02513-5 · Cited by 84
Karalis, F., Soubasi, V., Georgiou, T., Nakas, C. T., Simeonidou, C., Guiba-Tziampiri, O., & Spandou, E. (2011) · Brain Research · doi:10.1016/j.brainres.2011.09.044 · Cited by 84
Ko, W., Liaw, Y., Huang, J., Zhao, D., Chang, H., Ko, P., Jan, S., Nfor, O. N., Chiang, Y., & Lin, L. (2014) · Pediatric Anesthesia · doi:10.1111/pan.12371 · Cited by 84
Effects of PCBs, p,p′-DDT, p,p′-DDE, HCB and β-HCH on thyroid function in preschool children
Álvarez-Pedrerol, M., Ribas‐Fitó, N., Torrent, M., Carrizo, D., Grimalt, J. O., & Sunyer, J. (2007) · Occupational and Environmental Medicine · doi:10.1136/oem.2007.032763 · Cited by 84
Children’s low-level pesticide exposure and associations with autism and ADHD: a review
Roberts, J. R., Dawley, E. H., & Reigart, J. R. (2018) · Pediatric Research · doi:10.1038/s41390-018-0200-z · Cited by 84
Sadeghi, M., Peeri, M., & Hosseini, M.-J. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.05.017 · Cited by 83
Culbreth, M. E., Harrill, J., Freudenrich, T. M., Mundy, W. R., & Shafer, T. J. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.05.012 · Cited by 83
Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice
Lippert, R. N., Hess, S., Klemm, P., Burgeno, L. M., Jahans-Price, T., Walton, M. E., Kloppenburg, P., & Brüning, J. C. (2020) · Journal of Clinical Investigation · doi:10.1172/jci134412 · Cited by 83
Dockx, Y., Bijnens, E. M., Luyten, L. J., Peusens, M., Provost, E. B., Rasking, L., Sleurs, H., Hogervorst, J. G. F., Plusquin, M., Casas, L., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107094 · Cited by 83
Bisphenol-A Impairs Myelination Potential During Development in the Hippocampus of the Rat Brain
Tiwari, S. K., Agarwal, S., Chauhan, L. K. S., Mishra, V. N., & Chaturvedi, R. K. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8817-3 · Cited by 83
Sutton, P., Woodruff, T. J., Perron, J. L., Stotland, N. E., Conry, J. A., Miller, M. D., & Giudice, L. C. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2012.01.034 · Cited by 83
Microtubule-associated targets in chlorpyrifos oxon hippocampal neurotoxicity
Prendergast, M., Self, R. L., Smith, K. J., Ghayoumi, L., Mullins, M. M., Butler, T. R., Buccafusco, J. J., Gearhart, D. A., & Terry, A. V. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.01.023 · Cited by 83
Fontaine, C. J., Patten, A. R., Sickmann, H. M., Helfer, J. L., & Christie, B. R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.02.014 · Cited by 83
Refining the critical period for methamphetamine-induced spatial deficits in the Morris water maze
Williams, M. T., Moran, M. S., & Vorhees, C. V. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1433-y · Cited by 83
Environmental Toxicology: Children at Risk
Carroquino, M. J., Posada, M., & Landrigan, P. J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5764-0_11 · Cited by 82
Li, K., Li, L., Cui, B., Gai, Z., Li, Q., Wang, S., Yan, J., Lin, B., Tian, L., Liu, H., et al. (2017) · Toxicological Sciences · doi:10.1093/toxsci/kfx240 · Cited by 82
Energy metabolism in childhood neurodevelopmental disorders
Oyarzábal, A., Musokhranova, U., Barros, L. F., & García‐Cazorla, À. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103474 · Cited by 83
Hollins, S. L., Zavitsanou, K., Walker, F. R., & Cairns, M. J. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.99 · Cited by 82
Zhu, P., Hao, J., Tao, R., Huang, K., Jiang, X.-M., Zhu, Y., & Tao, F. (2015) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-015-0701-9 · Cited by 82
Cai, J., Tuong, C. M., Zhang, Y., Shields, C. B., Guo, G., Fu, H. Q., & Gozal, D. (2011) · The Journal of Pathology · doi:10.1002/path.2980 · Cited by 82
Mercury in Children: Current State on Exposure through Human Biomonitoring Studies
Ruggieri, F., Majorani, C., Domanico, F., & Alimonti, A. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14050519 · Cited by 82
Audet, M. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100772 · Cited by 82
Fried, P. A., Watkinson, B., & Gray, R. (2006) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2006.06.003 · Cited by 81
Stagni, F., Giacomini, A., Emili, M., Trazzi, S., Guidi, S., Sassi, M., Ciani, E., Rimondini, R., & Bartesaghi, R. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.07.031 · Cited by 81
Silva, M. H. (2020) · Birth Defects Research · doi:10.1002/bdr2.1661 · Cited by 81
Högberg, H. T., Sá, R. D. C. D. S. E., Kleensang, A., Bouhifd, M., Ülker, Ö. C., Smirnova, L., Behl, M., Maertens, A., Zhao, L., & Härtung, T. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02903-2 · Cited by 83
Lein, P. J., Yang, D., Bachstetter, A. D., Tilson, H. A., Harry, G. J., Mervis, R. F., & Kodavanti, P. R. S. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.9773 · Cited by 81
Jenkins, L. W., Peters, G., Dixon, C. E., Zhang, X., Clark, R. S. B., Skinner, J. C., Marion, D. W., Adelson, P. D., & Kochanek, P. M. (2002) · Journal of Neurotrauma · doi:10.1089/08977150260139101 · Cited by 81
Qiao, D., Seidler, F. J., Abreu‐Villaça, Y., Tate, C. A., Cousins, M. M., & Slotkin, T. A. (2003) · Developmental Brain Research · doi:10.1016/j.devbrainres.2003.10.004 · Cited by 81
Zhong, C., Tessing, J., Lee, B. K., & Lyall, K. (2020) · Autism Research · doi:10.1002/aur.2402 · Cited by 80
Metadata
- Authors
- Rice, D., & Barone, S.
- Affiliations
- Environmental Protection Agency (US)
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-06-01
- Volume
- 108
- Issue
- suppl 3
- Pages
- 511-533
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC1637807
- OpenAlex
- W2120095635
- Cited by
- 2,944
- References
- 455
- Citations by year
- 2026: 46 · 2025: 94 · 2024: 148 · 2023: 180 · 2022: 173 · 2021: 181 · 2020: 177 · 2019: 163 · 2018: 168 · 2017: 141 · 2016: 150 · 2015: 183 · 2014: 141 · 2013: 124 · 2012: 124
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Environmental Health Perspectives (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- U.S. Environmental Protection Agency
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Anesthesia and Neurotoxicity Research
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
- Keywords
- critical period, developmental neurotoxicity, brain development, neuronal proliferation, neuronal migration, neuronal differentiation, synaptogenesis, myelination, apoptosis, early life exposure, X-ray irradiation, methylazoxymethanol, ethanol, lead, methylmercury, chlorpyrifos, behavioral development, brain maturation, schizophrenia, dyslexia, epilepsy, autism spectrum disorder, age-related cognitive decline
- MeSH terms
- Adult, Aged, Aging, Animals, Cell Differentiation, Cell Movement, Child, Child, Preschool, Female, Embryonic and Fetal Development, Humans, Infant, Infant, Newborn, Middle Aged, Nervous System, Neuronal Plasticity, Neurotoxins, Pregnancy, Primates, Time Factors, Xenobiotics, Apoptosis, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
