Cited by 51Vector-borne infectious diseasesVector-Borne Animal DiseasesBartonella species infections research

Multiple vector-borne pathogens of domestic animals in Egypt

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Abdullah, Hend H. A. M., Amanzougaghene, Nadia, Dahmana, Handi, Louni, Meriem, Raoult, Didier, Mediannikov, Oleg·2021·PLOS Neglected Tropical Diseases

Abstract

Vector Borne Diseases (VBDs) are considered emerging and re-emerging diseases that represent a global burden. The aim of this study was to explore and characterize vector-borne pathogens in different domestic animal hosts in Egypt. A total of 557 blood samples were collected from different animals using a convenience sampling strategy (203 dogs, 149 camels, 88 cattle, 26 buffaloes, 58 sheep and 33 goats). All samples were tested for multiple pathogens using quantitative PCR and standard PCR coupled with sequencing. We identified Theileria annulata and Babesia bigemina in cattle (15.9 and 1.1%, respectively),T.ovis in sheep and buffaloes (8.6 and 7.7%, respectively) and Ba.canis in dogs (0.5%) as well as Anaplasma marginale in cattle, sheep and camels (20.4, 3.4 and 0.7%, respectively) and Coxiella burnetii in sheep and goats (1.7 and 3%; respectively). New genotypes of An.centrale,An.ovis,An.platys-like and Borrelia theileri were found in cattle (1.1,3.4, 3.4 and 3.4%, respectively),An.platys-like in buffaloes (7.7%),An.marginale,An.ovis,An.platys-like and Bo.theileri in sheep (3.4, 1.7, 1.7 and 3.4%, respectively),An.platys,An.platys-like and Setaria digitata in camels (0.7, 5.4 and 0.7%, respectively) and Rickettsia africae-like,An.platys,Dirofilaria repens and Acanthocheilonema reconditum in dogs (1.5, 3.4, 1 and 0.5%, respectively). Co-infections were found in cattle, sheep and dogs (5.7, 1.7, 0.5%, respectively). For the first time, we have demonstrated the presence of several vector-borne zoonoses in the blood of domestic animals in Egypt. Dogs and ruminants seem to play a significant role in the epidemiological cycle of VBDs.

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Crossref · 10.1371/journal.pntd.0009767

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  • Setariosis caused by different Setaria spp. is a filarial disease affecting bovines and can accidentally be transmitted into unusual hosts such as horses, donkeys, sheep, goats, and camels.

    “Setariosis caused by different Setaria spp. is a filarial disease affecting bovines and can accidentally be transmitted into unusual hosts such as horses, donkeys, sheep, goats, and camels [38,39,40,41].”

    From Emergent and Neglected Equine Filariosis in Egypt: Species Diversity and Host Immune Response (2022) · cites this paper as [41]

    The Introduction identifies Setaria digitata as a filarial nematode of cattle and buffaloes and names camels and horses as accidental hosts. The Discussion adds donkeys, sheep and goats as unnatural hosts, but these passages discuss S. digitata specifically, not disease caused by different Setaria species. (LLM, conf=0.86)

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Research works printed but not linked: 4

  1. [27]Constable PD, Hinchcli KW, Done SH, Grünberg W. Diseases of the Hemolymphatic and Immune Systems. In Veterinary Medicine, 11th ed.; Saunders, W.B., Ed.; Saunders Ltd.: London, UK, 2017.
  2. [36]Abdel-Shafy S, Abdullah HAMH, El-Molla A, Salib AF, Ghazy AA. Epidemiology and diagnosis of rickettsiosis in animal hosts and tick vectors. Bulg J Vet Med. 2018; 22: 371– 98.
  3. [48]Reynolds, M. G. Serologic evidence for exposure to spotted fever and typhus group rickettsioses among persons with acute febrile illness in Egypt. In: Proceedings of Fourth International Conference on Emerging Infectious Diseases, Atlanta. 2004.
  4. [119]Khalifa ON, Elhofy IF, Fahmy AH, Mona M, Sobhy MM, Agag MA. Seroprevalence and molecular detection of Coxiella burnetii infection in sheep, goats and human in Egypt. ISOI J Microbiol Biotechnol Food Sci. 2016; 2(1): 1– 7.

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Authors
Abdullah, H. H. A. M., Amanzougaghene, N., Dahmana, H., Louni, M., Raoult, D., & Mediannikov, O.
Affiliations
Aix-Marseille Université (FR)
Corresponding author
Mediannikov, Oleg
Venue
PLOS Neglected Tropical Diseases
Published
2021-09-29
Volume
15
Issue
9
Pages
e0009767
ISSN
  • 1935-2727 (ISSN-L)
  • 1935-2735
OpenAlex
W3204066213
Cited by
51
References
147
Citations by year
2026: 5 · 2025: 11 · 2024: 16 · 2023: 8 · 2022: 9 · 2021: 2
FWCI
6.61
Type
journal article
Language
en
Open access
Locations
  • PLoS neglected tropical diseases (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Greater South Information System
Funders
  • the Institut Hospitalo-Universitaire (IHU) Méditerranée Infection
  • National Research Agency (ANR-10-IAHU-03)
  • Région Provence Alpes Côte d'Azur
  • European funding FEDER PRIMI
  • Science and Technology Development Fund
  • Institut Francais d’Egypte (30652)
Topics
  • Life Sciences › Immunology and Microbiology › Parasitology › Vector-borne infectious diseases
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Vector-Borne Animal Diseases
  • Life Sciences › Immunology and Microbiology › Parasitology › Bartonella species infections research
Keywords
vector-borne diseases, domestic animals, Theileria annulata, Theileria ovis, Babesia bigemina, Babesia canis, Anaplasma marginale, Coxiella burnetii, Borrelia theileri, Rickettsia africae, Dirofilaria repens, Acanthocheilonema reconditum, co-infection, zoonoses, dogs, camels, cattle, sheep, goats, buffalo, Egypt
MeSH terms
Vector Borne Diseases, Animals, Animals, Domestic, Babesia, Bacteria, Bacterial Infections, Cross-Sectional Studies, Egypt, Filariasis, Filarioidea, Protozoan Infections, Animal, Prevalence, Phyllachorales

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