Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

Saederup, Noah, Cardona, Astrid E., Croft, Kelsey, Mizutani, Makiko, Cotleur, Anne C., Tsou, Chia-Lin, Ransohoff, Richard M., Charo, Israel F.·2010·PLoS ONE

DOI 10.1371/journal.pone.0013693

Cited by (601)

Items 101–200 of 601

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Abutbul, Shai, Shapiro, Jenny, Szaingurten‐Solodkin, Irit, Levy, Nitzan, Carmy, Yaron, Baron, Rona, Jung, Steffen, Monsonego, Alon · 2012 · Glia
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Hellwig, Sabine, Heinrich, Annette, Biber, Knut · 2013 · Frontiers in Cellular Neuroscience
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Chiot, Aude, Zaïdi, Sakina, Iltis, Charlène, Ribon, Matthieu, Berriat, Félix, Schiaffino, Lorenzo, Jolly, Ariane, de la Grange, Pierre, Mallat, Michel, Bohl, Delphine et al. · 2020 · Nature Neuroscience
Immune surveillance of the lung by migrating tissue monocytes
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Bo‐Ran Choi, Kory R. Johnson, Dragan Maric, Dorian B. McGavern · 2023 · Nature Immunology
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Liew, Pei Xiong, Lee, Woo-Yong, Kubes, Paul · 2017 · Immunity
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Lidia García‐Bonilla, Giuseppe Faraco, Jamie M. R. Moore, Michelle Murphy, Gianfranco Racchumi, Jayashree Srinivasan, David Brea, Costantino Iadecola, Josef Anrather · 2016 · Journal of Neuroinflammation
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Adham Fani Maleki, Serge Rivest · 2019 · Frontiers in Cellular Neuroscience
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Juan Antonio Ardura, Gorjana Rackov, Elena Izquierdo, Verónica Alonso, Arancha R. Gortázar, María Marta Escribese · 2019 · Frontiers in Pharmacology
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Magdalena Kocur, Reiner Schneider, Ann-Kathrin Pulm, Jens Bauer, Sonja Kropp, Michael Gliem, Jens Ingwersen, Norbert Goebels, Judith Alferink, Tim Prozorovski et al. · 2015 · Acta Neuropathologica Communications
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Ting Yang, Guohai Xu, Phillip T. Newton, Andrei S. Chagin, Souren Mkrtchian, Mattias Carlström, Xing‐Mei Zhang, Robert Adam Harris, Mary L. Cooter, Miles Berger et al. · 2018 · British Journal of Anaesthesia
CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow
Naoki Fujimura, Baohui Xu, Jackson Dalman, Hongping Deng, Kohji Aoyama, Ronald L. Dalman · 2015 · Scientific Reports
Diversity of transcriptomic microglial phenotypes in aging and Alzheimer's disease
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Mitsuhiko Katoh, Bao Jun Wu, Huy Bang Nguyen, Truc Quynh Thai, Ryo Yamasaki, Haiyan Lu, Anna M. Rietsch, Musab M. Zorlu, Youichi Shinozaki, Yurika Saitoh et al. · 2017 · Scientific Reports
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Grabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M, Wollscheid-Lengeling, Evi, Ozdemir, Derya D, Stables, Jennifer, Luke, Garry A, Ryan, Martin D, Adamson, Antony, Humphreys, Neil E et al. · 2020 · The Journal of Immunology
CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice
Jordi Pedragosa, Francesc Miró‐Mur, Amaia Otxoa-de-Amezaga, Carles Justicia, Francisca Ruíz-Jaén, Peter Ponsaerts, Manolis Pasparakis, Anna Maria Planas · 2020 · Journal of Cerebral Blood Flow & Metabolism
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Mastorakos, Panagiotis, Mihelson, Nicole, Luby, Marie, Burks, Scott R., Johnson, Kory, Hsia, Amie W., Witko, Jaclyn, Frank, Joseph A., Latour, Lawrence, McGavern, Dorian B. · 2021 · Nature Neuroscience
A deficiency in CCR2+ monocytes: the hidden side of Alzheimer’s disease
Naert, Gaëlle, Rivest, Serge · 2013 · Journal of Molecular Cell Biology
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Luciana Romina Frick, Christopher Pittenger · 2016 · Journal of Immunology Research
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Knut P. H. Biber, Thomas Möller, Erik Boddeke, Marco Prinz · 2015 · Nature Reviews Drug Discovery
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Zhenying Han, Li Li, Liang Wang, Vincent Degos, Mervyn Maze, Hua Su · 2014 · Journal of Neurochemistry
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Buonfiglioli, Alice, Efe, Ibrahim E., Guneykaya, Dilansu, Ivanov, Andranik, Huang, Yimin, Orlowski, Elisabeth, Krüger, Christina, Deisz, Rudolf A., Markovic, Darko, Flüh, Charlotte et al. · 2019 · Cell Reports
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Ishani De, Megan D. Steffen, Paul A. Clark, Clayton J. Patros, Emily Sokn, Stephanie M. Bishop, Suzanne J. Litscher, Vilena I. Maklakova, John S. Kuo, Fausto J. Rodríguez et al. · 2016 · Cancer Research
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Nuruddeen D. Lewis, Jonathan D. Hill, Kathryn W. Juchem, Dimitria E. Stefanopoulos, Louise Kelly Modis · 2014 · Journal of Neuroimmunology
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Pierre-Louis Loyher, Juliette Rochefort, Camille Baudesson de Chanville, Pauline Hamon, Géraldine Lescaille, Chloé Bertolus, Maude Guillot‐Delost, Matthew F. Krummel, Francois Michel Lemoine, Christophe Combadière et al. · 2016 · Cancer Research
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Ronning, Kaitryn E., Karlen, Sarah J., Miller, Eric B., Burns, Marie E. · 2019 · Scientific Reports
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Wenxin Ma, Yikui Zhang, Chun Gao, Robert N. Fariss, Johnny Tam, Wai T. Wong · 2017 · Scientific Reports
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Lijie Feng, Madhuvika Murugan, Dale B. Bosco, Yong Liu, Jiyun Peng, Gregory A. Worrell, Hai‐Long Wang, Lauren E. Ta, Jason R. Richardson, Yuxian Shen et al. · 2019 · Glia
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Deborah A. Lipski, Rémi Dewispelaere, Vincent Foucart, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns, François Willermain · 2017 · Journal of Neuroinflammation
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Boakye, Paul A., Tang, Shao-Jun, Smith, Peter A. · 2021 · Frontiers in Pain Research
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Maj‐Linda B. Selenica, Jennifer A. Alvarez, Kevin R. Nash, Daniel C. Lee, Chuanhai Cao, Xiaoyang Lin, Patrick Reid, Peter R. Mouton, David Morgan, Marcia N. Gordon · 2013 · Journal of Neuroinflammation
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Eleftherios I. Paschalis, Fengyang Lei, Chengxin Zhou, Vassiliki Kapoulea, Reza Dana, James Chodosh, Demetrios G. Vavvas, Claes Henrik Dohlman · 2018 · Proceedings of the National Academy of Sciences
Polarization of macrophages and microglia in inflammatory demyelination
Li Cao, Cheng He · 2013 · Neuroscience Bulletin
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Vainchtein, I. D., Vinet, J., Brouwer, N., Brendecke, S., Biagini, G., Biber, K., Boddeke, H. W. G. M., Eggen, B. J. L. · 2014 · Glia
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Xue Yao, Sandro Matosevic · 2021 · Cytokine & Growth Factor Reviews
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Hong‐Ru Chen, Ching‐Wen Chen, Yi-Min Kuo, Brandon Chen, Irena S. Kuan, Henry Huang, Jolly Lee, Neil R. Anthony, Chia-Yi Kuan, Yu Sun · 2021 · Theranostics
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Beccari, Sol, Sierra-Torre, Virginia, Valero, Jorge, Pereira-Iglesias, Marta, García-Zaballa, Mikel, Soria, Federico N., De Las Heras-Garcia, Laura, Carretero-Guillen, Alejandro, Capetillo-Zarate, Estibaliz, Domercq, Maria et al. · 2023 · Autophagy
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Athanasios I. Lourbopoulos, Ali Ertürk, Farida Hellal · 2015 · Frontiers in Cellular Neuroscience
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Catherine Alice Hawley, Rocío Rojo, Anna Raper, Kristin A. D. Sauter, Zofia M. Lisowski, Kathleen Grabert, Calum C. Bain, Gemma M. Davis, Pieter A. Louwe, Michael C. Ostrowski et al. · 2018 · The Journal of Immunology
Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain
Zhijun Zhang, Yu‐Lin Dong, Ying Lu, Su Cao, Zhi‐Qi Zhao, Yong‐Jing Gao · 2012 · Journal of Neuroinflammation
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Stefan Roth, Vikramjeet Singh, Steffen Tiedt, Lisa Schindler, G. Carl Huber, Arie Geerlof, Daniel James Antoine, Antoine Anfray, Cyrille Orset, Maxime Gauberti et al. · 2018 · Science Translational Medicine
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Jenny A. Garcia, Paula A. Pino, Makiko Mizutani, Sandra M. Cardona, Israel F. Charo, Richard M. Ransohoff, Thomas G. Forsthuber, Astrid E. Cardona · 2013 · The Journal of Immunology
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Y. Ishida, Y. Kuninaka, M. Nosaka, M. Furuta, A. Kimura, A. Taruya, Hiroki Yamamoto, E. Shimada, M. Akiyama, N. Mukaida et al. · 2019 · Journal of Investigative Dermatology
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Takashi Umekawa, Ahmed M. Osman, Wei Han, Tomoaki Ikeda, Klas Blomgren · 2015 · Glia
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Gyoneva, Stefka, Kim, Daniel, Katsumoto, Atsuko, Kokiko-Cochran, O. Nicole, Lamb, Bruce T., Ransohoff, Richard M. · 2015 · Journal of Neuroinflammation
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Violeta Chiţu, Fabrizio Biundo, Gabriel G. L. Shlager, Eun Su Park, Ping Wang, Maria E. Gulinello, Şölen Gökhan, Harmony C. Ketchum, Kusumika Saha, Michael A. Deture et al. · 2020 · Cell Reports
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury
Josh M. Morganti, Lara‐Kirstie Riparip, Austin Chou, Sharon Liu, Nalin M. Gupta, Susanna Rosi · 2016 · Journal of Neuroinflammation
Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia
Wei Han, Takashi Umekawa, Kai Zhou, Xing‐Mei Zhang, Makiko Ohshima, Cecilia A Dominguez, Robert Adam Harris, Changlian Zhu, Klas Blomgren · 2016 · Oncotarget
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Xi Feng, Timothy D. Jopson, Maria Serena Paladini, Sharon Liu, Brian L. West, Nalin M. Gupta, Susanna Rosi · 2016 · Journal of Neuroinflammation
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Peter Ludewig, Mattia Gallizioli, Xabier Urra, Sarah Behr, Vanessa H. Brait, Mathias Gelderblom, Tim Ullrich Magnus, Anna Maria Planas · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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Keiko Hirose, Song-Zhe Li, Kevin K. Ohlemiller, Richard M. Ransohoff · 2014 · Journal of the Association for Research in Otolaryngology
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Rohit Rao, Rong Han, Sean Ogurek, Chengbin Xue, Lai Man Natalie Wu, Liguo Zhang, Li Zhang, JIAN LI HU, Timothy N. Phoenix, Stephen N. Waggoner et al. · 2021 · Neuro-Oncology
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Benjamin J. Kopecky, Hao Dun, Junedh Amrute, Chieh‐Yu Lin, Andrea L. Bredemeyer, Yuriko Terada, Peter O. Bayguinov, Andrew L. Koenig, Christian Corbin Frye, James A. J. Fitzpatrick et al. · 2022 · Circulation
Microglia: origins, homeostasis, and roles in myelin repair
Amy F. Lloyd, Claire Linzi Davies, Véronique E. Miron · 2017 · Current Opinion in Neurobiology
Monocyte-derived S1P in the lymph node regulates immune responses
Audrey Baeyens, Sabrina Bracero, V Sai Chaluvadi, Alireza Khodadadi‐Jamayran, Michael Cammer, Susan R. Schwab · 2021 · Nature
Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain
Austin Chou, Karen Krukowski, Josh M. Morganti, Lara‐Kirstie Riparip, Susanna Rosi · 2018 · International Journal of Molecular Sciences
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Shweta S. Puntambekar, Maha Saber, Bruce T. Lamb, Olga N. Kokiko‐Cochran · 2018 · Brain Behavior and Immunity
Transmembrane protein 119 is neither a specific nor a reliable marker for microglia
Elise Vankriekelsvenne, Uta Chrzanowski, Katerina Manzhula, Theresa Greiner, Andreas Wree, Alexander Hawlitschka, Gemma Llovera, Jiangshan Zhan, Sarah Joost, Christoph Schmitz et al. · 2022 · Glia