Objectively Measured Walking Duration and Sedentary Behaviour and Four-Year Mortality in Older People
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BACKGROUND: Physical activity is an important component of health. Recommendations based on sensor measurements are sparse in older people. The aim of this study was to analyse the effect of objectively measured walking and sedentary duration on four-year mortality in community-dwelling older people. METHODS: Between March 2009 and April 2010, physical activity of 1271 participants (≥65 years, 56.4% men) from Southern Germany was measured over one week using a thigh-worn uni-axial accelerometer (activPAL; PAL Technologies, Glasgow, Scotland). Mortality was assessed during a four-year follow-up. Cox-proportional-hazards models were used to estimate the associations between walking (including low to high intensity) and sedentary duration with mortality. Models were adjusted for age and sex, additional epidemiological variables, and selected biomarkers. RESULTS: An inverse relationship between walking duration and mortality with a minimum risk for the 3rd quartile (102.2 to128.4 minutes walking daily) was found even after multivariate adjustment with HRs for quartiles 2 to 4 compared to quartile 1 of 0.45 (95%-CI: 0.26; 0.76), 0.18 (95%-CI: 0.08; 0.41), 0.39 (95%-CI: 0.19; 0.78), respectively. For sedentary duration an age- and sex-adjusted increased mortality risk was observed for the 4th quartile (daily sedentary duration ≥1137.2 min.) (HR 2.05, 95%-CI: 1.13; 3.73), which diminished, however, after full adjustment (HR 1.63, 95%-CI: 0.88; 3.02). Furthermore, our results suggest effect modification between walking and sedentary duration, such that in people with low walking duration a high sedentary duration was noted as an independent factor for increased mortality. CONCLUSIONS: In summary, walking duration was clearly associated with four-year overall mortality in community-dwelling older people.
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Objectively measured physical activity levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death.
“Objectively measured PA levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [36]
MVPA measured with triaxial accelerometers is associated with lower mortality than light physical activity or sedentary behaviour in several US cohorts and a Swedish population-based cohort.
“Moderate-to-vigorous physical activity (MVPA), measured with the use of triaxial accelerometers, was associated with a lower mortality than light physical activity or sedentary behaviour in several US cohorts and in a Swedish population-based cohort34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [36]
Wearable-measured physical activity has an inverse dose-dependent relationship with all-cause mortality.
“Several studies have shown wearable-measured physical activity to have an inverse dose-dependent relationship with all-cause mortality5,34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [36]
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- Authors
- Klenk, J., Dallmeier, D., Denkinger, M. D., Rapp, K., Koenig, W., Rothenbacher, D., & ActiFE Study Group
- Affiliations
- Universität Ulm (DE)
- Corresponding author
- Klenk, Jochen
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-04-15
- Volume
- 11
- Issue
- 4
- Pages
- e0153779
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4833405
- OpenAlex
- W2336288341
- Cited by
- 63
- References
- 45
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 13 · 2021: 4 · 2020: 7 · 2019: 12 · 2018: 3 · 2017: 6
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- mediaTUM (Technical University of Munich) (submittedVersion)
- Funders
- Ministry of Science, Research and Arts, state of Baden-Wuerttemberg, Germany
- “Hertha-Nathorff” Program at the Ulm University
- Robert Bosch Foundation, Stuttgart, Germany
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- walking time, sedentary behavior, mortality, older adults, physical activity, accelerometer-measured activity, effect modification, community-dwelling older adults
- MeSH terms
- Aged, Aged, 80 and over, Aging, Female, Germany, Health Status, Hemodynamics, Humans, Male, Middle Aged, Mortality, Motor Activity, Prospective Studies, Biomarkers, Proportional Hazards Models, Walking, Exercise Tolerance, Sedentary Behavior, Accelerometry
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