Acidification of blood is superior to sodium fluoride alone as an inhibitor of glycolysis
Abstract
Background: Sodium fluoride is the preferred agent to inhibit glycolysis. Its action is not immediate, however, and complete inhibition is delayed for up to 4 hours. A more effective method is needed. Acidification of blood combined with the addition of NaF and EDTA appears to be such a method. We studied whether acidification was indeed more effective than NaF. Methods: We conducted 6 independent studies over a 10-month period at 3 Quest Diagnostics laboratory sites. In each study, we drew venous blood from 6–24 nonfasting employee volunteers into 3 or 4 different serum- or plasma-collection tubes, which were stored under different conditions and aliquoted at different times. We analyzed the aliquots in duplicate by means of a hexokinase-based enzymatic method. Results: The mean glucose concentration decreased by 0.3% at 2 h and by 1.2% at 24 h when blood was drawn into tubes containing citrate buffer, NaF, and EDTA. In contrast, the mean glucose concentration decreased by 4.6% at 2 h and by 7.0% at 24 h when blood was drawn into tubes containing NaF and sodium oxalate. Conclusions: Acidification should replace NaF alone as the recommended method for obtaining an accurate glucose concentration. Diagnostic cut points based on blood samples collected into tubes containing NaF as the only inhibitor of glycolysis are likely to be too low.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, A., Metzger, B. E., & Nathan, D. M. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.161596 · Cited by 1,360 · see citing works
Sacks, D. B., Bruns, D. E., Goldstein, D. E., Maclaren, N. K., McDonald, J. M., & Parrott, M. A. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.3.436 · Cited by 1,128 · see citing works
Effectiveness of sodium fluoride as a preservative of glucose in blood
Chan, A. Y., Swaminathan, R., & Cockram, C. S. (1989) · Clinical Chemistry · doi:10.1093/clinchem/35.2.315 · Cited by 289 · see citing works
Stabilization of Glucose in Blood Specimens: Mechanism of Delay in Fluoride Inhibition of Glycolysis
Mikesh, L. M., & Bruns, D. E. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.102160 · Cited by 114 · see citing works
M. Stahl, L. G. M. J. (2001) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/003655101300133612 · Cited by 79 · see citing works
A new method of inhibiting glycolysis in blood samples
Uchida, K., Matuse, R., Toyoda, E., Okuda, S., & Tomita, S. (1988) · Clinica Chimica Acta · doi:10.1016/0009-8981(88)90125-8 · Cited by 53 · see citing works
Waring, W. S., Evans, L. E., & Kirkpatrick, C. T. (2007) · Journal of Clinical Pathology · doi:10.1136/jcp.2006.039925 · Cited by 42 · see citing works
Normal Fasting Plasma Glucose Levels and Type 2 Diabetes
Gambino, R., Reichberg, S. B., & Schwartz, J. G. (2006) · New England Journal of Medicine · doi:10.1056/nejmc052984 · Cited by 8 · see citing works
Self-citation
Flagged first, then by citations
1 of the 9 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
International Expert Committee report on the role of the A1c assay in the diagnosis of diabetes
The International Expert Committee (2009) · Diabetes Care · doi:10.2337/dc09-9033 · Cited by 3,185 · see citing works
Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, A., Metzger, B. E., & Nathan, D. M. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.161596 · Cited by 1,360 · see citing works
Hod, M., Kapur, A., Sacks, D. A., Hadar, E., Agarwal, M., Di Renzo, G. C., Roura, L. C., McIntyre, H. D., Morris, J. L., & Divakar, H. (2015) · International Journal of Gynecology & Obstetrics · doi:10.1016/s0020-7292(15)30033-3 · Cited by 767 · see citing works
Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, A., Metzger, B. E., & Nathan, D. M. (2011) · Diabetes Care · doi:10.2337/dc11-9998 · Cited by 718 · see citing works
A European Evidence-Based Guideline for the Prevention of Type 2 Diabetes
Paulweber, B., Valensi, P. E., Lindström, J., Lalic, N. M., Greaves, C. J., McKee, M., Kissimova‐Skarbek, K., Liatis, S., Cosson, E., Szendroedi, J., et al. (2010) · Hormone and Metabolic Research · doi:10.1055/s-0029-1240928 · Cited by 469 · see citing works
A1c versus glucose testing: a comparison
Sacks, D. B. (2011) · Diabetes Care · doi:10.2337/dc10-1546 · Cited by 461 · see citing works
Principles of fluoride toxicity and the cellular response: a review
Johnston, N. R., & Strobel, S. A. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02687-5 · Cited by 368 · see citing works
Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Lernmark, Å., Metzger, B. E., Nathan, D. M., & Kirkman, M. S. (2023) · Diabetes Care · doi:10.2337/dci23-0036 · Cited by 351 · see citing works
“Loss of glucose can be minimized in two classic ways: 1) immediate separation of plasma from blood cells after blood collection [the glucose concentration is stable for 8 h at 25°C and 72 h at 4°C in separated, nonhemolyzed, sterile serum without fluoride (61)]; and 2) placing the blood tube in an ice–water slurry imm…”
Impact of blood collection devices on clinical chemistry assays
Bowen, R. A. R., Hortin, G. L., Csákó, G., Otañez, O. H., & Remaley, A. T. (2009) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2009.10.001 · Cited by 241 · see citing works
Sacks, D. B., Arnold, M. A., Bakris, G. L., Bruns, D. E., Horvath, A. R., Lernmark, Å., Metzger, B. E., Nathan, D. M., & Kirkman, M. S. (2023) · Clinical Chemistry · doi:10.1093/clinchem/hvad080 · Cited by 157 · see citing works
Stabilization of glucose in blood samples: why it matters
Bruns, D. E., & Knowler, W. C. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2009.126037 · Cited by 125 · see citing works
Seclen, S. N., Rosas, M. E., Arias, A. J., Huayta, E. C. N. Q., & Medina, C. A. (2015) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2015-000110 · Cited by 114 · see citing works
Luppa, P. B., Bietenbeck, A., Beaudoin, C. A., & Giannetti, A. E. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.01.003 · Cited by 89 · see citing works
Potter, J. M., Hickman, P. E., Oakman, C., Woods, C., & Nolan, C. J. (2020) · Diabetes Care · doi:10.2337/dc20-0304 · Cited by 71 · see citing works
Sample management for clinical biochemistry assays: Are serum and plasma interchangeable specimens?
Lima-Oliveira, G., Monneret, D., Guerber, F., & Guidi, G. C. (2018) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2018.1499708 · Cited by 55 · see citing works
Rioja, R. G., Martínez, D., Segovia, M., Ibarz, M., Llopis, M. A., Bauçà, J. M., Marzana, I., Barba, N., Ventura, M., del Pino, I. G., et al. (2018) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2017-1189 · Cited by 52 · see citing works
Sodium fluoride: an ineffective inhibitor of glycolysis
Gambino, R. (2012) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012135 · Cited by 50 · see citing works
Self-citationStability of glucose in plasma with different anticoagulants
Fobker, M. (2014) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2013-1049 · Cited by 47 · see citing works
It takes acid, rather than ice, to freeze glucose
van den Berg, S. A. A., Thelen, M. H. M., Salden, L. P. W., van Thiel, S. W., & Boonen, K. J. M. (2015) · Scientific Reports · doi:10.1038/srep08875 · Cited by 49 · see citing works
What is the most suitable blood collection tube for glucose estimation?
Dimeski, G., Yow, K. S., & Brown, N. N. (2014) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563214544708 · Cited by 50 · see citing works
Quality Indicators for the Prevention of Type 2 Diabetes in Europe – IMAGE
Pajunen, P., Landgraf, R., Muylle, F., Neumann, A., Lindström, J., Schwarz, P. E. H., Peltonen, M., Acosta, T., Adler, M., Alkerwi, A., et al. (2010) · Hormone and Metabolic Research · doi:10.1055/s-0029-1240976 · Cited by 48 · see citing works
Turchiano, M., Nguyen, C., Fierman, A., Lifshitz, M., & Convit, A. (2013) · Journal of Environmental and Public Health · doi:10.1155/2013/256151 · Cited by 46 · see citing works
Bowen, R. A. R., & Adcock, D. M. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.10.004 · Cited by 44 · see citing works
Balicco, A., Oleko, A., Szego, E., Boschat, L., Deschamps, V., Saoudi, A., Zeghnoun, A., & Fillol, C. (2017) · Annales de Toxicologie Analytique · doi:10.1016/j.toxac.2017.06.003 · Cited by 39 · see citing works
Which sample tube should be used for routine glucose determination?
Bonetti, G., Cancelli, V., Coccoli, G., Piccinelli, G., Brugnoni, D., Caimi, L., & Carta, M. (2015) · Primary care diabetes · doi:10.1016/j.pcd.2015.11.003 · Cited by 39 · see citing works
Glucose measurement in body fluids: A ready reckoner for clinicians
Kubihal, S., Goyal, A., Gupta, Y., & Khadgawat, R. (2020) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2020.11.021 · Cited by 40 · see citing works
Hahnefeld, L., Gurke, R., Thomas, D., Schreiber, Y., Schäfer, S. M. G., Trautmann, S., Snodgrass, I. F., Kratz, D., Geißlinger, G., & Ferreirós, N. (2019) · Talanta · doi:10.1016/j.talanta.2019.120593 · Cited by 37 · see citing works
Pre-analytical and analytical aspects affecting clinical reliability of plasma glucose results
Pasqualetti, S., Braga, F., & Panteghini, M. (2017) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2017.03.009 · Cited by 41 · see citing works
It’s Time for a Better Blood Collection Tube to Improve the Reliability of Glucose Results
Peake, M. J., Bruns, D. E., Sacks, D. B., & Horvath, A. R. (2012) · Diabetes Care · doi:10.2337/dc12-1312 · Cited by 36 · see citing works
Citric/citrate buffer: an effective antiglycolytic agent
del Pino, I. G., Constanso, I. P., Mourín, L. V., Safont, C. B., & Vázquez, P. R. (2013) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2012-0735 · Cited by 33 · see citing works
Fernandez, L., Jee, P., Klein, M.-J., Fischer, P. Q., Perkins, S. L., & Brooks, S. P. J. (2012) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2012.11.027 · Cited by 33 · see citing works
Italian joint SIBioC-SIPMeL Study Group on Diabetes Mellitus, Bonetti, G., Carta, M., Montagnana, M., Cascio, C. L., Bonfigli, A. R., Mosca, A., & Testa, R. (2016) · Biochemia Medica · doi:10.11613/bm.2016.006 · Cited by 32 · see citing works
Blood Glucose Determination: Effect of Tube Additives
Lippi, G., Nybo, M., Cadamuro, J., Guimarães, J. T., van Dongen-Lases, E. C., & Šimundić, A.-M. (2018) · Advances in clinical chemistry · doi:10.1016/bs.acc.2017.12.003 · Cited by 32 · see citing works
Diagnosis of gestational diabetes mellitus will be flawed until we can measure glucose
Bruns, D. E., Metzger, B. E., & Sacks, D. B. (2020) · Clinical Chemistry · doi:10.1093/clinchem/hvz027 · Cited by 30 · see citing works
Relative efficacy of different strategies for inhibition of in vitro glycolysis
Fischer, M. M., Hannemann, A., Winter, T., Schäfer, C., Petersmann, A., & Nauck, M. (2021) · Clinical Chemistry · doi:10.1093/clinchem/hvab071 · Cited by 28 · see citing works
Carey, R., Lunt, H., Heenan, H. F., Frampton, C. M. A., & Florkowski, C. M. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.05.017 · Cited by 26 · see citing works
Bennett, K. A., Turner, L. M., Millward, S., Moss, S. E. W., & Hall, A. J. (2017) · Conservation Physiology · doi:10.1093/conphys/cox013 · Cited by 26 · see citing works
Seclen, S. N., Rosas, M. E., Arias, A. J., & Medina, C. A. (2017) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2017-000401 · Cited by 26 · see citing works
Technical and clinical validation of the Greiner FC-Mix glycaemia tube
van der Hagen, E. A. E., Fokkert, M. J., Kleefman, A. M. D., Thelen, M., van den Berg, S. A. A., & Slingerland, R. J. (2017) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2016-0944 · Cited by 25 · see citing works
Juričić, G., Bakliža, A., Saračević, A., Kopčinović, L. M., Dobrijević, S., Drmić, S., & Šimundić, A.-M. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2015-0746 · Cited by 24 · see citing works
Borg, R., Persson, F., Siersma, V., Lind, B., Olivarius, N. D. F., & Andersen, C. L. (2018) · Diabetic Medicine · doi:10.1111/dme.13776 · Cited by 24 · see citing works
Mansouri, K., Rastegari‐Pouyani, M., Ghanbari-Movahed, M., Safarzadeh, M., Kiani, S., & Ghanbari‐Movahed, Z. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110694 · Cited by 24 · see citing works
Jamieson, E. L., Dimeski, G., Flatman, R., Hickman, P. E., Jones, G. R. D., Marley, J. V., McIntyre, D. H., McNeil, A. R., Nolan, C. J., Potter, J. M., et al. (2022) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2022.10.002 · Cited by 24 · see citing works
Juričić, G., Kopčinović, L. M., Saračević, A., Bakliža, A., & Šimundić, A.-M. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2015-0358 · Cited by 23 · see citing works
IMPORTANCE OF THE PRE-ANALYTICAL PHASE IN BLOOD GLUCOSE ANALYSIS
Janssen, K., & Delanghe, J. (2010) · Acta Clinica Belgica · doi:10.1179/acb.2010.068 · Cited by 21 · see citing works
Norman, M., & Jones, I. (2014) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2014.01.011 · Cited by 22 · see citing works
Ridefelt, P., Åkerfeldt, T., & Helmersson-Karlqvist, J. (2014) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2014.02.022 · Cited by 21 · see citing works
Point‐of‐care glucose monitoring on the neonatal unit
Makaya, T., Memmott, A., & Bustani, P. (2011) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2011.02253.x · Cited by 21 · see citing works
Stapleton, M., Daly, N., O’Kelly, R., & Turner, M. J. (2017) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563216682978 · Cited by 21 · see citing works
Bietenbeck, A., Geilenkeuser, W. J., Klawonn, F., Spannagl, M., Nauck, M., Petersmann, A., Thaler, M., Winter, C., & Luppa, P. B. (2018) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2017-1142 · Cited by 20 · see citing works
Fast test: Clinical practice and interpretation
Agin, A., Charrié, A., Chikh, K., Tabarin, A., & Vezzosi, D. (2013) · Annales d Endocrinologie · doi:10.1016/j.ando.2013.05.003 · Cited by 20 · see citing works
Stabilization of glucose in blood samples: out with the old, in with the new
Gambino, R., & Bruns, D. E. (2013) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2013-0341 · Cited by 20 · see citing works
Self-citationDaly, N., Flynn, I., Carroll, C., Stapleton, M., O'Kelly, R., & Turner, M. J. (2016) · Clinical Chemistry · doi:10.1373/clinchem.2016.254466 · Cited by 19 · see citing works
An important source of preanalytical error in medical laboratories: centrifugation
Sönmez, Ç., Gümüş, A., Şeneş, M., Aykal, G., Taneli, F., Aksungar, F. B., Avcı, E., Coşkun, C., Çınaroğlu, İ., Çolak, A., et al. (2021) · Turkish Journal of Biochemistry · doi:10.1515/tjb-2020-0262 · Cited by 19 · see citing works
Using glycated hemoglobin hba1c for diagnosis of diabetes mellitus: an indian perspective
Mahajan, R. D., & Mishra, B. (2011) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 19 · see citing works
Roy, D. R., Dzyuba, B., Policar, T., Malinovskyi, O., Rodina, M., & Dzyuba, V. (2021) · Biology · doi:10.3390/biology10080739 · Cited by 18 · see citing works
Validity of two point-of-care glucometers in the diagnosis of neonatal hypoglycemia
Ngerncham, S., Piriyanimit, S., Kolatat, T., Wongsiridej, P., Inchgarm, L., Kitsommart, R., Vutrapongwatana, P., & Jeerapaet, K. (2012) · Indian Pediatrics · doi:10.1007/s13312-012-0133-2 · Cited by 18 · see citing works
Nielsen, C., Pedersen, L. T., Lindholt, J. S., Mortensen, F. V., & Erlandsen, E. J. (2011) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2011.590900 · Cited by 18 · see citing works
Long-term stability of glucose: 96-h study using Terumo Glycaemia tubes
Winter, T., Greiser, A., Nauck, M., & Petersmann, A. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2015-0548 · Cited by 18 · see citing works
Perlee, D., van der Steege, K. H., & den Besten, G. (2021) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2021-0513 · Cited by 15 · see citing works
Gowda, G. A. N., Pascua, V., Hill, L., Djukovic, D., Wang, D. Y. Q., & Raftery, D. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c03719 · Cited by 15 · see citing works
Landberg, E., Nevander, S., Hadi, M. A., Blomberg, M. I., Norling, A., Ekman, B., & Lilliecreutz, C. (2021) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365513.2021.1980224 · Cited by 15 · see citing works
Long-term stability of glucose: glycolysis inhibitor vs. gel barrier tubes
Winter, T., Hannemann, A., Suchsland, J., Nauck, M. A., & Petersmann, A. (2018) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2017-0860 · Cited by 14 · see citing works
A Potential Issue with Screening Prediabetes or Diabetes Using Serum Glucose: A Delay in Diagnosis
Kang, J. G., Park, C., Ihm, S., & Park, S. W. (2016) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2016.40.5.414 · Cited by 13 · see citing works
Are fluoride-containing blood tubes still needed for glucose testing?
Bruns, D. E. (2013) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2013.01.009 · Cited by 13 · see citing works
Bonetti, G., Carta, M., Lapolla, A., Miccoli, R., Testa, R., & Mosca, A. (2018) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2018.09.013 · Cited by 12 · see citing works
Chan, H., Lunt, H., Thompson, H., Heenan, H. F., FRAMPTON, C. M. A., & Florkowski, C. M. (2014) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2013-1059 · Cited by 13 · see citing works
Inhibition of Glycolysis for Glucose Estimation in Plasma: Recent Guidelines and their Implications
Gupta, S. D., & Kaur, H. (2013) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-013-0405-1 · Cited by 12 · see citing works
Juričić, G., Saračević, A., Kopčinović, L. M., Bakliža, A., & Šimundić, A.-M. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.03.006 · Cited by 12 · see citing works
Saračević, A., Dukić, L., Juričić, G., Kopčinović, L. M., Mirošević, G., & Šimundić, A.-M. (2017) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2017-0279 · Cited by 12 · see citing works
A Comparison of Fasting Glucose and HbA1c for the Diagnosis of Diabetes Mellitus Among Korean Adults
Yun, W.-J., Shin, M., Kweon, S.-S., Park, K.-S., Lee, Y. H., Nam, H., Jeong, S., Yun, Y.-W., & Choi, J. (2010) · Journal of Preventive Medicine and Public Health · doi:10.3961/jpmph.2010.43.5.451 · Cited by 10 · see citing works
Stability of Glucose Concentrations in Frozen Plasma
Pleus, S., Freckmann, G., Baumstark, A., & Haug, C. (2020) · Journal of Diabetes Science and Technology · doi:10.1177/1932296820963657 · Cited by 10 · see citing works
Importance and Status of HBA1C in T2DM and its Indian Perspective
Sarmah, D., & Sharma, B. (2012) · Asian journal of biomedical and pharmaceutical sciences · doi:10.15272/ajbps.v2i12.60 · Cited by 10 · see citing works
Al-Kharusi, A., Al-Lawati, N., Al-Kindi, M., & Mula-Abed, W.-A. S. (2014) · Oman Medical Journal · doi:10.5001/omj.2014.109 · Cited by 10 · see citing works
Bonetti, G., & Carta, M. (2017) · Biochemia Medica · doi:10.11613/bm.2017.030901 · Cited by 10 · see citing works
Kristensen, K. H., Wangel, A., Katsarou, A., Shaat, N., Simmons, D. S., Fadl, H., & Berntorp, K. E. (2020) · Journal of Diabetes Research · doi:10.1155/2020/7937403 · Cited by 10 · see citing works
Kellerer, M., Schäfer-Graf, U. M., & Neonatologie, K. F. (2016) · Cited by 9 · see citing works
Szőke, D., Borille, S., Cardellicchio, M., Spadaccini, G., Taricco, E., Vignali, M., Cetin, I., Birindelli, S., & Panteghini, M. (2021) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2021-0706 · Cited by 9 · see citing works
Gupta, S., Gupta, A., Verma, M., Singh, K., Kaur, A., Chopra, B., & Kaur, V. (2016) · International Journal of Applied and Basic Medical Research · doi:10.4103/2229-516x.174010 · Cited by 8 · see citing works
Stabilization of Plasma Glucose: The Use of Newer Technology and Pragmatic Laboratory Practice
Coward, S. M., O'Neill, F. C., McAdam, L., Reilly, L., & McKeeman, G. C. (2018) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2018.027227 · Cited by 8 · see citing works
Steele, A. M., Wensley, K. J., Brewer, E., Shields, B. M., Hattersley, A. T., & McDonald, T. J. (2013) · Practical Diabetes · doi:10.1002/pdi.1758 · Cited by 8 · see citing works
Thermometric analysis of blood metabolites in ICU patients
Adlerberth, J., Meng, Q., Mecklenburg, M., Tian, Z., Zhou, Y., Bülow, L., & Xie, B. (2019) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-019-08873-7 · Cited by 7 · see citing works
Stolz, M., Schlawne, C., Hoffmann, J., Hartmann, V., Marini, I., Fritsche, A., Peter, A., Bakchoul, T., & Schick, F. (2020) · NMR in Biomedicine · doi:10.1002/nbm.4358 · Cited by 7 · see citing works
Haeckel, R., Wosniok, W., Torge, A., Junker, R., Bertram, A., Krebs, A., Özcürümez, M. K., Orth, M., & Streichert, T. (2020) · Journal of Laboratory Medicine · doi:10.1515/labmed-2020-0064 · Cited by 7 · see citing works
Segerer, H., Bührer, C., Kapellen, T. M., Mattern, E., Ramsauer, B., SOMVILLE, T., & Trotter, A. (2018) · Zeitschrift für Geburtshilfe und Neonatologie · doi:10.1055/a-0628-0873 · Cited by 7 · see citing works
Glucose sampling: importance of citrate
Carta, M., Montagnana, M., Cascio, C. L., Bonetti, G., & on behalf of the Italian joint SIBioC-SIPMeL study group on diabetes mellitus (2016) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563216645621 · Cited by 6 · see citing works
Time Is Glucose, Can't Miss Gestational Diabetes
Festa, R., Carta, M., Ceriello, A., & Testa, R. (2012) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2011.0225 · Cited by 6 · see citing works
Ohnmacht, C. M., Cooley, M., Darling, R. J., Lei, S., & Patel, V. (2019) · Bioanalysis · doi:10.4155/bio-2019-0238 · Cited by 6 · see citing works
Heilmann, G., Trenkamp, S., Möser, C., Bombrich, M., Schön, M., Yurchenko, I., Straßburger, K., Rodríguez, M. M., Zaharia, O., Burkart, V., et al. (2023) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2023-0770 · Cited by 5 · see citing works
Maintaining glucose integrity ex-vivo: Impact of preanalytical specimen handling
Islam, M. N., Lyons, C., Griffin, T. P., Hamon, S., Dunne, F., & O’Shea, P. M. (2023) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/00045632231199374 · Cited by 6 · see citing works
Should haemoglobin A1cbe used for the diagnosis of diabetes mellitus in South Africa?
George, J. A. (2011) · Journal of Endocrinology Metabolism and Diabetes of South Africa · doi:10.1080/22201009.2011.10872263 · Cited by 5 · see citing works
Diabetes diagnostics including analytical methods for glucose monitoring
Wahl, H. G., & Koschinsky, T. (2018) · Springer eBooks · doi:10.1007/978-3-662-54497-6_12 · Cited by 5 · see citing works
Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain
del Pino, I. G., Ibarz, M., Rioja, R. G., Salas, P., Segovia, M., Puente, J. J., Marzana, I., Ventura, M., Martínez, D., Llopis, M. A., et al. (2019) · Biochemia Medica · doi:10.11613/bm.2020.010704 · Cited by 5 · see citing works
Dibbasey, M., Price, C., Lawal, B., & Umukoro, S. (2024) · Practical Laboratory Medicine · doi:10.1016/j.plabm.2024.e00360 · Cited by 5 · see citing works
Sacks, D. B. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-6164-9.00026-3 · Cited by 5 · see citing works
Luppa, P. B., Zeller, M., Pieper, M., Kaiser, P., Weiss, N., Vierbaum, L., & Freckmann, G. (2024) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2024.1371426 · Cited by 4 · see citing works
Chakraborty, S., Ghosh, S. S., Das, A., Sawant, P., & Kallner, A. (2014) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2014-0644 · Cited by 4 · see citing works
Diagnostik des Gestationsdiabetes: Die Crux liegt bei der Blutentnahme
Kleinwechter, H. J., Heinemann, L., & Freckmann, G. (2015) · Deutsches Ärzteblatt · doi:10.3238/persdia.2015.04.24.06 · Cited by 4 · see citing works
Sample Processing and Specimen Misidentification Issues
Woodworth, A. L., & Pyle, A. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-415783-5.00004-9 · Cited by 4 · see citing works
False paraprotein-induced hypoglycemia in the measurement of glucose by the hexokinase method
Bossard, V., Sauvageon, Y., Fraissinet, F., Dreyfus, B., Thuillier, R., & Hauet, T. (2019) · Annales de biologie clinique · doi:10.1684/abc.2019.1465 · Cited by 4 · see citing works
- Authors
- Gambino, R., Piscitelli, J., Ackattupathil, T. A., Theriault, J. L., Andrin, R. D., Sanfilippo, M. L., & Etienne, M.
- Affiliations
- Quest Diagnostics (United States) (US)
- Teterboro, NJ
- West Hills, CA, and
- Miramar, FL
- Corresponding author
- Gambino, Raymond
- Venue
- Clinical Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-05-01
- Volume
- 55
- Issue
- 5
- Pages
- 1019-1021
- ISSN
- 0009-9147 (ISSN-L)
- 1530-8561
- OpenAlex
- W2156782964
- Cited by
- 160
- References
- 9
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 10 · 2019: 12 · 2018: 13 · 2017: 10 · 2016: 14 · 2015: 11 · 2014: 9 · 2013: 12 · 2012: 16
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Clinical Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Keywords
- sodium fluoride, glycolysis inhibition, EDTA, sodium oxalate, blood collection tubes, serum glucose, plasma glucose, blood sample storage, diagnostic thresholds
- MeSH terms
- Blood, Blood Glucose, Blood Preservation, Citrates, Diabetes Mellitus, Glycolysis, Humans, Hydrogen-Ion Concentration, Sodium Fluoride, Specimen Handling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
