AMP-Activated Protein Kinase is Highly Expressed in Neurons in the Developing Rat Brain and Promotes Neuronal Survival Following Glucose Deprivation

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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The AMP‐Activated Protein Kinase: Fuel Gauge of the Mammalian Cell?

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Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

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5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

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Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

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Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria

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Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

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Mammalian AMP-activated protein kinase subfamily

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Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca 2+ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

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A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

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5′‐AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP‐activated protein kinase. Studies using bacterially expressed human protein phosphatase‐2C <i>α</i> and native bovine protein phosphatase‐2A _c

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Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

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Dealing with energy demand: the AMP-activated protein kinase

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Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell‐permeable activator of AMP‐activated protein kinase

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NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

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Secreted Forms of β-Amyloid Precursor Protein Protect Hippocampal Neurons against Amyloid β-Peptide-Induced Oxidative Injury

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Role of the AMP-activated protein kinase in the cellular stress response

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AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β cells, and may regulate insulin release

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The early events of oxygen and glucose deprivation: setting the scene for neuronal death?

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Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle

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Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase.

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Dual regulation of the AMP‐activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle

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The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase

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Phosphorylation of bovine hormone‐sensitive lipase by the AMP‐activated protein kinase

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Growth Factors Prevent Mitochondrial Dysfunction, Loss of Calcium Homeostasis, and Cell Injury, but Not ATP Depletion in Hippocampal Neurons Deprived of Glucose

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

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Cellular Distribution and Developmental Expression of AMP‐Activated Protein Kinase Isoforms in Mouse Central Nervous System

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AMP-activated Protein Kinase Inhibits the Glucose-activated Expression of Fatty Acid Synthase Gene in Rat Hepatocytes

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Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP‐activated protein kinase

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Characterization of 5′AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

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Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP‐activated protein kinase: A sensitive mechanism to protect the cell against ATP depletion

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Strong nuclear factor-?B-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic alzheimer's disease superior temporal lobe neocortex

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Metyrapone, an Inhibitor of Glucocorticoid Production, Reduces Brain Injury Induced by Focal and Global Ischemia and Seizures

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The 5′‐AMP‐activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex

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4-Hydroxynonenal, a Product of Lipid Peroxidation, Damages Cholinergic Neurons and Impairs Visuospatial Memory in Rats

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Isoform-specific Purification and Substrate Specificity of the 5′-AMP-activated Protein Kinase

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Non-catalytic - and -Subunit Isoforms of the 5′-AMP-activated Protein Kinase

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Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase.

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AMP‐activated protein kinase isoenzyme family: subunit structure and chromosomal location

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Control of Hepatic Fatty Acid Oxidation by 5′-AMP-Activated Protein Kinase Involves a Malonyl-CoA-Dependent and a Malonyl-CoA-Independent Mechanism

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Specificity determinants for the AMP‐activated protein kinase and its plant homologue analysed using synthetic peptides

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Inhibition of Glucocorticoid-Induced Apoptosis with 5-Aminoimidazole-4-carboxamide Ribonucleoside, a Cell-Permeable Activator of AMP-Activated Protein Kinase

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Raf, but Not MEK or ERK, Is Sufficient for Differentiation of Hippocampal Neuronal Cells

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Catalytic subunits of the porcine and rat 5′-AMP-activated protein kinase are members of the SNF1 protein kinase family

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Identification of Raf‐1 Ser621 kinase activity from NIH 3T3 cells as AMP‐activated protein kinase

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Characterization of the Mononickel Metallocenter in H134A Mutant Urease

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

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AMPK in Health and Disease

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

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Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase

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Resveratrol stimulates AMP kinase activity in neurons

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Meta-analysis of Alzheimer’s disease risk with obesity, diabetes, and related disorders

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AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

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Metformin: An Old But Still the Best Treatment for Type 2 Diabetes

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AMPK at the Nexus of Energetics and Aging

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Neuroprotective action of resveratrol

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Caloric restriction and intermittent fasting: Two potential diets for successful brain aging

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AMPK inhibition in health and disease

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AMP-activated protein kinase: new regulation, new roles?

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Glycolysis: a bioenergetic or a survival pathway?

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The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation

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The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

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5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase

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Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

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Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

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Brain Glucose Sensing, Counterregulation, and Energy Homeostasis

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Hypothalamic AMPK: a canonical regulator of whole-body energy balance

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The Therapeutic Potential of Metformin in Neurodegenerative Diseases

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C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase*

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AMPK in the brain: its roles in energy balance and neuroprotection

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AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

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Energy metabolism in adult neural stem cell fate

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5-Aminoimidazole-4-Carboxamide-1-β-4-Ribofuranoside Inhibits Proinflammatory Response in Glial Cells: A Possible Role of AMP-Activated Protein Kinase

Giri, S., Nath, N., Smith, B., Viollet, B., Singh, A. K., & Singh, I. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4288-03.2004 · Cited by 266 · see citing works

Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism

Bruce, K. D., Zsombok, A., & Eckel, R. H. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00060 · Cited by 264 · see citing works

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

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AMP-activated Protein Kinase and p38 MAPK Activate O-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

Cheung, W. D., & Hart, G. W. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801222200 · Cited by 233 · see citing works

AMPK: Potential Therapeutic Target for Ischemic Stroke

Jiang, S., Li, T. X., Ji, T., Yi, W., Yang, Z. P., Wang, S., Yang, Y., & Gu, C. (2018) · Theranostics · doi:10.7150/thno.25674 · Cited by 252 · see citing works

AMP‐activated protein kinase: a potential player in Alzheimer’s disease

Salminen, A., Kaarniranta, K., Haapasalo, A., Soininen, H. S., & Hiltunen, M. O. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07331.x · Cited by 221 · see citing works

Ghrelin: a hormone regulating food intake and energy homeostasis

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Neuroprotective Effects of Adenosine Monophosphate- Activated Protein Kinase Inhibition and Gene Deletion in Stroke

Li, J., Zeng, Z., Viollet, B., Ronnett, G. V., & McCullough, L. D. (2007) · Stroke · doi:10.1161/strokeaha.107.490904 · Cited by 216 · see citing works

Leptin Stimulates Fatty Acid Oxidation and Peroxisome Proliferator-Activated Receptor α Gene Expression in Mouse C2C12 Myoblasts by Changing the Subcellular Localization of the α2 Form of AMP-Activated Protein Kinase

Suzuki, A., Okamoto, S., Lee, S. P., Saito, K., Shiuchi, T., & Minokoshi, Y. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02222-06 · Cited by 206 · see citing works

AMPK activation: Role in the signaling pathways of neuroinflammation and neurodegeneration

Peixoto, C. A., Oliveira, W. H. D., Araújo, S. M. D. R., & Nunes, A. K. S. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.08.013 · Cited by 196 · see citing works

Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein Kinase Mediates Tolerance to Glutamate Excitation in Neurons

Weisová, P., Concannon, C. G., Devocelle, M. C., Prehn, J. H. M., & Ward, M. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0354-09.2009 · Cited by 176 · see citing works

Developing a head for energy sensing: AMP‐activated protein kinase as a multifunctional metabolic sensor in the brain

Ramamurthy, S., & Ronnett, G. V. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.110122 · Cited by 159 · see citing works

Effects of AMP-Activated Protein Kinase in Cerebral Ischemia

Li, J., & McCullough, L. D. (2009) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2009.255 · Cited by 163 · see citing works

AMPK in the brain: its roles in glucose and neural metabolism

Muraleedharan, R., & Dasgupta, B. (2021) · FEBS Journal · doi:10.1111/febs.16151 · Cited by 164 · see citing works

Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK

Li, Y., Munoz-Mayorga, D., Nie, Y., Kang, N., Tao, Y., Lagerwall, J., Pernaci, C., Curtin, G., Coufal, N. G., Mertens, J., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.03.014 · Cited by 160 · see citing works

Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson’s Disease

Curry, D. W., Stutz, B., Andrews, Z. B., & Elsworth, J. D. (2018) · Journal of Parkinson s Disease · doi:10.3233/jpd-171296 · Cited by 159 · see citing works

Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

Choi, I.-Y., Ju, C., Jalin, A. M. A. A., Lee, D. I., Prather, P. L., & Kim, W.-K. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.11.024 · Cited by 157 · see citing works

Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease

Zhang, K., Zhu, S., Li, J., Jiang, T., Feng, L., Pei, J., Wang, G., Ouyang, L., & Liu, B. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.02.016 · Cited by 158 · see citing works

AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

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Berberine suppresses neuroinflammatory responses through AMP‐activated protein kinase activation in BV‐2 microglia

Lu, D., Tang, C., Chen, Y., & Wei, I. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22580 · Cited by 151 · see citing works

Potential Role for AMP-Activated Protein Kinase in Hypoglycemia Sensing in the Ventromedial Hypothalamus

McCrimmon, R. J., Fan, X., Ding, Y., Zhu, W., Jacob, R. J., & Sherwin, R. S. (2004) · Diabetes · doi:10.2337/diabetes.53.8.1953 · Cited by 148 · see citing works

Redox Homeostasis and Cellular Stress Response in Aging and Neurodegeneration

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AICA riboside both activates AMP‐activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus

Gadalla, A. E., Pearson, T., Currie, A. J., Dale, N., Hawley, S. A., Sheehan, M., Hirst, W. D., Michel, A. D., Randall, A. D., Hardie, D. G., et al. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02253.x · Cited by 145 · see citing works

The role of LKB1 and AMPK in cellular responses to stress and damage

Alexander, A., & Walker, C. L. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.03.010 · Cited by 144 · see citing works

Adiponectin is Protective against Oxidative Stress Induced Cytotoxicity in Amyloid-Beta Neurotoxicity

Chan, K., Lam, K. S. L., Cheng, O.-Y., Kwan, J., Ho, P. W., Cheng, K. K. Y., Chung, S. K., Ho, J. W.-M., Guo, V. Y., & Xu, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052354 · Cited by 140 · see citing works

Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism

Lv, Y., Liang, T., Wang, G., & Li, Z. (2018) · Bioscience Reports · doi:10.1042/bsr20181061 · Cited by 141 · see citing works

AMPK: A cellular metabolic and redox sensor. A minireview

Shirwany, N. A. (2014) · Frontiers in bioscience · doi:10.2741/4218 · Cited by 142 · see citing works

Role of Neuronal Energy Status in the Regulation of Adenosine 5′-Monophosphate-Activated Protein Kinase, Orexigenic Neuropeptides Expression, and Feeding Behavior

Lee, K., Li, B., Xi, X., Suh, Y., & Martin, R. J. (2004) · Endocrinology · doi:10.1210/en.2004-0968 · Cited by 138 · see citing works

Leptin and the systems neuroscience of meal size control

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AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3

King, T. D., Song, L., & Jope, R. S. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.03.005 · Cited by 136 · see citing works

5-Aminoimidazole-4-Carboxamide Ribonucleoside: A Novel Immunomodulator with Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis

Nath, N., Giri, S., Prasad, R. C., Salem, M. L., Singh, A. K., & Singh, I. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.1.566 · Cited by 136 · see citing works

AMP-Activated Protein Kinase Phosphorylates Retinoblastoma Protein to Control Mammalian Brain Development

Dasgupta, B., & Milbrandt, J. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.01.005 · Cited by 133 · see citing works

Expanding roles for AMP‐activated protein kinase in neuronal survival and autophagy

Poels, J., Spasić, M. R., Callaerts, P., & Norga, K. (2009) · BioEssays · doi:10.1002/bies.200900003 · Cited by 130 · see citing works

Fatty acid metabolism as a target for obesity treatment.

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C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

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AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors

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Reciprocal Inhibition of p53 and Nuclear Factor-κB Transcriptional Activities Determines Cell Survival or Death in Neurons

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AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

Domise, M., Didier, S., Marinangeli, C., Zhao, H., Chandakkar, P., Buée, L., Viollet, B., Davies, P., Marambaud, P., & Vingtdeux, V. (2016) · Scientific Reports · doi:10.1038/srep26758 · Cited by 120 · see citing works

Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells

Hallows, K. R., Kobinger, G., Wilson, J. M., Witters, L. A., & Foskett, J. K. (2003) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00227.2002 · Cited by 116 · see citing works

Endurance factors improve hippocampal neurogenesis and spatial memory in mice

Kobilo, T., Yuan, C., & van Praag, H. (2011) · Learning &amp; Memory · doi:10.1101/lm.2001611 · Cited by 114 · see citing works

5′-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells

Garcia‐Gil, M., Pesi, R., Perna, S., Allegrini, S., Giannecchini, M., Camici, M., & Tozzi, M. G. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00836-9 · Cited by 112 · see citing works

Macrophage migration inhibitory factor (MIF) promotes cell survival and proliferation of neural stem/progenitor cells

Ohta, S., Misawa, A., Fukaya, R., Inoue, S., Kanemura, Y., Okano, H., Kawakami, Y., & Toda, M. (2012) · Journal of Cell Science · doi:10.1242/jcs.102210 · Cited by 110 · see citing works

AMP-Activated Protein Kinase (AMPK) Molecular Crossroad for Metabolic Control and Survival of Neurons

Spasić, M. R., Callaerts, P., & Norga, K. K. (2009) · The Neuroscientist · doi:10.1177/1073858408327805 · Cited by 109 · see citing works

A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion

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Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family

Cho, S. H., Ahn, A., Bhargava, P., Lee, C., Eischen, C. M., McGuinness, O. P., & Boothby, M. R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017082108 · Cited by 108 · see citing works

Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells

Peairs, A., Radjavi, A., Davis, S., Li, L., Ahmed, A. A., Giri, S., & Reilly, C. M. (2009) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2009.03924.x · Cited by 106 · see citing works

Chronic stress-induced memory deficits are reversed by regular exercise via AMPK-mediated BDNF induction

Kim, D.-M., & Leem, Y. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.019 · Cited by 104 · see citing works

Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma

Sharma, S., Zhuang, Y., Ying, Z., Wu, A., & Gómez‐Pinilla, F. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.04.042 · Cited by 103 · see citing works

AMP-activated protein kinase is activated in Parkinson’s disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Choi, J., Park, C., & Jeong, J. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.11.022 · Cited by 103 · see citing works

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window

Lanzillotta, A., Pignataro, G., Branca, C., Cuomo, O., Sarnico, I., Benarese, M., Annunziato, L., Spano, P., & Pizzi, M. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.08.018 · Cited by 102 · see citing works

Mitochondrial dysfunction and Parkinson disease: a Parkin–AMPK alliance in neuroprotection

Hang, L., Thundyil, J., & Lim, K. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12820 · Cited by 101 · see citing works

Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice

Zhu, S., Wang, J., Zhang, Y., Li, V., Kong, J., He, J., & Li, X. (2014) · Brain Research · doi:10.1016/j.brainres.2014.06.002 · Cited by 100 · see citing works

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

Cai, Y., Martens, G. A., Hinke, S. A., Heimberg, H., PIPELEERS, D. G., & de Casteele, M. V. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.09.018 · Cited by 99 · see citing works

Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites

Jiang, P., Gan, M., Ebrahim, A. S., Castanedes‐Casey, M., Dickson, D. W., & Yen, S.-H. C. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.11.001 · Cited by 99 · see citing works

O-GlcNAc Protein Modification in Cancer Cells Increases in Response to Glucose Deprivation through Glycogen Degradation

Kang, J. G., Park, S., Ji, S., Jang, I., Park, S., Kim, H. S., Kim, S., Yook, J. I., Park, Y. I., Roth, J., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.026351 · Cited by 92 · see citing works

Synaptic Activity and Bioenergy Homeostasis: Implications in Brain Trauma and Neurodegenerative Diseases

Khatri, N., & Man, H. (2013) · Frontiers in Neurology · doi:10.3389/fneur.2013.00199 · Cited by 91 · see citing works

Oxidative stress modulates Sir2α in rat hippocampus and cerebral cortex

Wu, A., Ying, Z., & Gómez‐Pinilla, F. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04807.x · Cited by 90 · see citing works

5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNFα-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling

Su, R.-Y., Chao, Y., Chen, T., Huang, D.-Y., & Lin, W. (2007) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0800 · Cited by 90 · see citing works

Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis

Won, J., Im, Y., Kim, J., Singh, A. K., & Singh, I. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.07.081 · Cited by 89 · see citing works

Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots

Yang, S.-H., Li, W., Sumien, N., Forster, M. J., Simpkins, J. W., & Liu, R. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.10.005 · Cited by 86 · see citing works

Dorsal Hindbrain 5′-Adenosine Monophosphate-Activated Protein Kinase as an Intracellular Mediator of Energy Balance

Hayes, M. R., Skibicka, K. P., Bence, K. K., & Grill, H. J. (2008) · Endocrinology · doi:10.1210/en.2008-1319 · Cited by 87 · see citing works

AMP-Activated Protein Kinase: A New Beta-Cell Glucose Sensor?

Leclerc, I., & Rutter, G. A. (2004) · Diabetes · doi:10.2337/diabetes.53.suppl_3.s67 · Cited by 86 · see citing works

5-Aminoimidazole-4-carboxamide-ribonucleoside enhances oxidative stress-induced apoptosis through activation of nuclear factor-κB in mouse Neuro 2a neuroblastoma cells

Jung, J. E., Lee, J., Ha, J., Kim, S. S., Cho, Y. H., Baik, H. H., & Kang, I. (2003) · Neuroscience Letters · doi:10.1016/j.neulet.2003.10.012 · Cited by 86 · see citing works

Regulation of AMP-activated protein kinase activity by G-protein coupled receptors: Potential utility in treatment of diabetes and heart disease

Hutchinson, D. S., Summers, R. J., & Bengtsson, T. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.05.008 · Cited by 85 · see citing works

Characterization of the AMP-activated protein kinase pathway in chickens

Proszkowiec‐Weglarz, M., Richards, M. P., Ramachandran, R., & McMurtry, J. P. (2005) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2005.10.009 · Cited by 85 · see citing works

A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

Hashiesh, H. M., Sharma, C., Goyal, S. N., Sadek, B. S., Jha, N. K., Kaabi, J. A., & Ojha, S. K. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111639 · Cited by 90 · see citing works

Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats

Xu, N., Zhang, Y., Doycheva, D. M., Ding, Y. P., Zhang, Y., Tang, J., Guo, H., & Zhang, J. H. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.02.024 · Cited by 82 · see citing works

Role of 5′-Adenosine Monophosphate-Activated Protein Kinase in Cell Survival and Death Responses in Neurons

Weisová, P., Dávila, D., Tuffy, L. P., Ward, M. W., Concannon, C. G., & Prehn, J. H. M. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3544 · Cited by 83 · see citing works

Adiponectin protects rat hippocampal neurons against excitotoxicity

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Intracerebroventricular Infusion of Glucose, Insulin, and the Adenosine Monophosphate-Activated Kinase Activator, 5-Aminoimidazole-4-Carboxamide-1-β- d -Ribofuranoside, Controls Muscle Glycogen Synthesis

Perrin, C., Knauf, C., & Burcelin, R. (2004) · Endocrinology · doi:10.1210/en.2004-0270 · Cited by 80 · see citing works

The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe Disease

Giri, S., Khan, M., Nath, N., Singh, I., & Singh, A. K. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05279.x · Cited by 78 · see citing works

Mesenchymal stem cell-derived extracellular vesicles promote microglial M2 polarization after subarachnoid hemorrhage in rats and involve the AMPK/NF-κB signaling pathway

Han, M., Cao, Y., Guo, X., Chu, X., Li, T., Xue, H., Xin, D., Yuan, L., Ke, H., Li, G., et al. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111048 · Cited by 77 · see citing works

Involvement of AMP‐activated protein kinase in neuroinflammation and neurodegeneration in the adult and developing brain

Saito, M., Saito, M., & Das, B. C. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.01.007 · Cited by 73 · see citing works

AMPK in the brain: its roles in glucose and neural metabolism

Muraleedharan, R., & Dasgupta, B. (2021) · FEBS Journal · doi:10.1111/febs.16151 · Cited by 164 · see citing works

AMP-Activated Protein Kinase (AMPK) Molecular Crossroad for Metabolic Control and Survival of Neurons

Spasić, M. R., Callaerts, P., & Norga, K. K. (2009) · The Neuroscientist · doi:10.1177/1073858408327805 · Cited by 109 · see citing works

A Pharmacological Activator of AMP-Activated Protein Kinase Protects Hypoxic Neurons in a Concentration-Dependent Manner

Zhang, X., Gao, R.-K., Li, J., Qi, Y., Song, X., Zhao, L., Wang, H., Pu, Y., Xu, K., & Li, J. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0186-3 · Cited by 17 · see citing works

A Protective Partnership

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Role of 5′-Adenosine Monophosphate-Activated Protein Kinase in Cell Survival and Death Responses in Neurons

Weisová, P., Dávila, D., Tuffy, L. P., Ward, M. W., Concannon, C. G., & Prehn, J. H. M. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3544 · Cited by 83 · see citing works