Gold nanoparticles: an era in bionanotechnology
Abstract
INTRODUCTION: Gold nanoparticles have been efficiently and effectively used for the delivery of biomolecules and genes along with the potential to offer extremely sensitive diagnostics and imaging methods. AREAS COVERED: This review discusses the historical aspects, synthesis of gold nanoparticles, gold nanoparticles as drug delivery vehicles, photothermal effect of gold nanoparticles and the applications of gold nanoparticles. Gold nanoparticles with their unique optical properties may be useful as biosensors in living cells and has application in the field of drug delivery and photothermal therapy. Depending on the size, shape and degree of aggregation and nature of the protecting organic shells on their surface, gold nanoparticles can appear red, blue and other colors and emit bright resonance light of various wavelengths, which falls under visible region. Because of this property, gold nanoparticles have been extensively used as probes for sensing/imaging a wide range of analysts/targets such as proteins, cells and nucleic acids. EXPERT OPINION: Gold nanoparticles provide an admirable platform for the delivery of biomolecules and genes.
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Gold nanoparticles have a large surface area and can be utilized to load or bind to any genetic or biological part, thereby widely used for sensing/imaging/therapy of various targets such as proteins, cells and nucleic acids.
“Gold nanoparticles have a large surface area and can be utilized to load or bind to any genetic or biological part, thereby widely used for sensing/imaging/therapy of various targets such as proteins, cells and nucleic acids.88”
From Smart nanoparticles for cancer therapy (2023) · cites this paper as [88]
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- Authors
- Kumar, D., Saini, N., Jain, N., Sareen, R., & Pandit, V.
- Affiliations
- Shoolini University (IN)
- Al-Ameen College of Pharmacy (IN)
- Venue
- Expert Opinion on Drug Delivery
- Publisher
- Informa Healthcare
- Published
- 2013-01-07
- Volume
- 10
- Issue
- 3
- Pages
- 397-409
- ISSN
- 1742-5247 (ISSN-L)
- 1744-7593
- OpenAlex
- W1982563407
- Cited by
- 96
- References
- 118
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 9 · 2023: 10 · 2022: 3 · 2021: 9 · 2020: 6 · 2019: 7 · 2018: 5 · 2017: 4 · 2016: 9 · 2015: 11 · 2014: 7 · 2013: 5
- FWCI
- 0.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Expert Opinion on Drug Delivery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- gold nanoparticles, nanobiotechnology, gold nanoparticle synthesis, drug carriers, photothermal effect, photothermal therapy, biosensors, optical properties, surface plasmon resonance, gene delivery, biomolecule delivery, imaging agents
- MeSH terms
- Diagnostic Imaging, Gold, Humans, Drug Delivery Systems, Nanotechnology, Nanoparticles
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