Cited by 140Memory and Neural MechanismsNeuroscience and Neuropharmacology ResearchCholinesterase and Neurodegenerative Diseases

Cholinergic projections from the basal forebrain of rat to the amygdala

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Nagai, T, Kimura, H, Maeda, T, McGeer, PL, Peng, F, McGeer, EG·1982·The Journal of Neuroscience

Abstract

Cholinergic afferents to the amygdala from the basal forebrain were studied using di-isopropyl fluorophosphate-AChE histochemistry in combination with retrograde tracing using various fluorescent dyes. Cells sending their axons to the amygdala and staining intensely for AChE were located mainly in the nucleus of the substantia innominata. They also were found in the ventral part of the globus pallidus, the horizontal limb of the nucleus tractus diagonalis Broca, and the nucleus interstitialis ansae lenticularis. A correspondence was established between these cells and cells staining for choline acetyltransferase by immunohistochemistry in both distribution and morphology. Non-cholinergic neurons which send their axons to the amygdala also were found in the substantia innominata complex.

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Crossref · 10.1523/jneurosci.02-04-00513.1982

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  1. Heimer, L., and R. D. WiIIson (1975) The subcortical projec- tions of the allocortex: Similarities in the neural associations of the hippocampus, the piriform cortex, and the neocortex. In Golgi Centennial Symposium, M. Santini, ed., pp. 177- 193, Raven Press, New York.

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Authors
Nagai, T., Kimura, H., Maeda, T., McGeer, P., Peng, F., & McGeer, E.
Affiliations
University of British Columbia (CA)
Venue
The Journal of Neuroscience
Published
1982-04-01
Volume
2
Issue
4
Pages
513-520
ISSN
  • 0270-6474 (ISSN-L)
  • 1529-2401
OpenAlex
W1949870697
Cited by
140
References
29
Citations by year
2025: 1 · 2024: 3 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2016: 4 · 2015: 1 · 2013: 2
FWCI
7.50
Type
journal article
Language
en
Open access
Locations
  • Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • OUKA (Osaka University Knowledge Archive) (Osaka University) (submittedVersion)
Funders
  • Medical Research Council Canada
  • Medical Research Council
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Health Sciences › Medicine › Pharmacology › Cholinesterase and Neurodegenerative Diseases
Keywords
cholinergic projections, amygdala, basal forebrain, substantia innominata, globus pallidus, choline acetyltransferase, acetylcholinesterase histochemistry, retrograde tracing, cholinergic afferents
MeSH terms
Acetylcholinesterase, Amygdala, Animals, Brain, Choline O-Acetyltransferase, Cholinergic Fibers, Globus Pallidus, Isoflurophate, Rats

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