The DOI matches its Crossref record; 41 of the 42 references it cites were found in a registry or an index.
Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex
Open accessAbstract
Glucose is the primary energetic substrate of the brain, and measurements of its metabolism are the basis of major functional cerebral imaging methods. Contrary to the general view that neurons are fueled solely by glucose in proportion to their energetic needs, recent in vitro and ex vivo analyses suggest that glucose preferentially feeds astrocytes. However, the cellular fate of glucose in the intact brain has not yet been directly observed. We have used a real-time method for measuring glucose uptake in astrocytes and neurons in vivo in male rats by imaging the trafficking of the nonmetabolizable glucose analog 6-deoxy-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-aminoglucose (6-NBDG) using two-photon microscopy. During resting conditions we found that astrocytes and neurons both take up 6-NBDG at the same rate in the barrel cortex of the rat. However, during intense neuronal activity triggered by whisker stimulation, astrocytes rapidly accelerated their uptake, whereas neuronal uptake remained almost unchanged. After the stimulation period, astrocytes returned to their preactivation rates of uptake paralleling the neuronal rate of uptake. These observations suggest that glucose is taken up primarily by astrocytes, supporting the view that functional imaging experiments based on glucose analogs extraction may predominantly reflect the metabolic activity of the astrocytic network.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The first study (Chuquet et al., 2010) used the fluorescent glucose analogue 6-NBDG; because it cannot be phosphorylated by hexokinase (given that the 6 position was already occupied by the fluorophore), this analogue’s accumulation may not correspond with the actual rate of glucose utilization, and it has been shown in some cases to correlate negatively with glucose utilization (DiNuzzo et al., 2”
From Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) · cites this paper as Chuquet et al., 2010
In the citing paper
“Two recent in vivo studies monitored glucose analogue accumulation in somatosensory cortex during whisker stimulation; they used two different glucose analogues and obtained opposite results.”
From Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) · cites this paper as Chuquet et al., 2010
In the citing paper
“The first study (Chuquet et al., 2010) used the fluorescent glucose analogue 6-NBDG; because it cannot be phosphorylated by hexokinase (given that the 6 position was already occupied by the fluorophore), this analogue’s accumulation may not correspond with the actual rate of glucose utilization, and it has been shown in some cases to correlate negatively with glucose utilization (DiNuzzo et al., 2”
From Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) · cites this paper as Chuquet et al., 2010
In the citing paper
“Baseline accumulation of the analogue into astrocytes and neurons was similar; upon whisker stimulation in anesthetized rats, uptake into both cell types tended to increase, though only significantly for astrocytes (Chuquet et al., 2010).”
From Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) · cites this paper as Chuquet et al., 2010
In the citing paper
“Baseline accumulation of the analogue into astrocytes and neurons was similar; upon whisker stimulation in anesthetized rats, uptake into both cell types tended to increase, though only significantly for astrocytes (Chuquet et al., 2010).”
From Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) · cites this paper as Chuquet et al., 2010
In the citing paper
“In vivo measurements to learn which cell type shows greater stimulated uptake of glucose analogs have given conflicting results (Chuquet et al., 2010; Lundgaard et al., 2015)”
From Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake (2017) · cites this paper as Chuquet et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
An Energy Budget for Signaling in the Grey Matter of the Brain
Attwell, D., & Laughlin, S. B. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200110000-00001 · Cited by 3,543
Raichle, M. E., & Mintun, M. A. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112819 · Cited by 1,630
Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission
Rouach, N., Koulakoff, A., Abudara, V., Willecke, K., & Giaume, C. (2008) · Science · doi:10.1126/science.1164022 · Cited by 912
Herrero-Mendez, A., Almeida, A., Fernández, E., Maestre, C., Moncada, S., & Bolaños, J. P. (2009) · Nature Cell Biology · doi:10.1038/ncb1881 · Cited by 844
RELATION BETWEEN PHYSIOLOGICAL FUNCTION AND ENERGY METABOLISM IN THE CENTRAL NERVOUS SYSTEM
Sokoloff, L. (1977) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1977.tb03919.x · Cited by 807
Activity-dependent regulation of energy metabolism by astrocytes: an update
Pellerin, L., Bouzier‐Sore, A., Aubert, A., Serres, S., Merle, M., Costalat, R., & Magistretti, P. J. (2007) · Glia · doi:10.1002/glia.20528 · Cited by 805
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn, A., Kirchhoff, F., Kerr, J. N. D., & Helmchen, F. (2004) · Nature Methods · doi:10.1038/nmeth706 · Cited by 784
Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging
Magistretti, P. J., & Pellerin, L. (1999) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1999.0471 · Cited by 750
Astrocyte Responses to CNS Injury
Norenberg, M. D. (1994) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199405000-00001 · Cited by 589
Hertz, L., Peng, L., & Dienel, G. A. (2007) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600343 · Cited by 587
Cited by
Sorted by citations
Items 101–200 of 219
Astrocytic β2 Adrenergic Receptor Gene Deletion Affects Memory in Aged Mice
Jensen, C. J., Demol, F., Bauwens, R., Kooijman, R., Massie, A., Villers, A., Ris, L., & De Keyser, J. (2016) · PLOS ONE · doi:10.1371/journal.pone.0164721 · Cited by 32
Bhatti, M. S., & Frostig, R. D. (2023) · Scientific Reports · doi:10.1038/s41598-023-39574-9 · Cited by 35
Neural Metabolic Networks: Key Elements of Healthy Brain Function
Madrer, N., Perera, N. D., Uccelli, N. A., Abbondanza, A., Andersen, J. V., Carsana, E. V., Demmings, M. D., Fernandez, R. F., de Fragas, M. G., Gbadamosi, I., et al. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70084 · Cited by 37
Brain activity-induced neuronal glucose uptake/glycolysis: Is the lactate shuttle not required?
Tang, B. L. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.12.010 · Cited by 36
Verkhratsky, A., & Butt, A. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821565-4.00008-0 · Cited by 31
Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke
Thieren, L., Zanker, H. S., Droux, J., Dalvi, U., Wyss, M. T., Waag, R., Germain, P., von Ziegler, L., Looser, Z. J., Hösli, L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59400-2 · Cited by 38
Clozapine induces astrocyte-dependent FDG-PET hypometabolism
Rocha, A., Bellaver, B., Souza, D. G., Schu, G., Fontana, I. C., Venturin, G. T., Greggio, S., Fontella, F. U., Schiavenin, M. L., Machado, L. S., et al. (2022) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-022-05682-3 · Cited by 31
Dias, C., Fernandes, E., Barbosa, R. M., Laranjinha, J. A. N., & Ledo, A. (2023) · BioFactors · doi:10.1002/biof.1951 · Cited by 30
Lourenço, C. F., Ledo, A., Laranjinha, J. A. N., Gerhardt, G. A., & Barbosa, R. M. (2016) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2016.06.083 · Cited by 29
Novel therapeutic approaches to target neurodegeneration
de la Fuente, A. G., Pelucchi, S., Mertens, J., Luca, M. D., Mauceri, D., & Marcello, E. E. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16078 · Cited by 32
Functional Magnetic Resonance Imaging
Leblanc, R., & Zatorre, R. J. (1997) · Journal of neurosurgery · doi:10.3171/jns.1997.86.2.0316 · Cited by 29
The computational power of the human brain
Gebicke‐Haerter, P. J. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1220030 · Cited by 35
What Is the Role of Lactate in Brain Metabolism, Plasticity, and Neurodegeneration?
Benarroch, E. E. (2024) · Neurology · doi:10.1212/wnl.0000000000209378 · Cited by 32
Oheim, M., Schmidt, E. M., & Hirrlinger, J. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.04.011 · Cited by 28
Neuron‐glia (mis)interactions in brain energy metabolism during aging
Mayorga-Weber, G. A., Rivera, F. J., & Castro, M. A. (2022) · Journal of Neuroscience Research · doi:10.1002/jnr.25015 · Cited by 27
Persistent blood glucose reduction upon repeated transcranial electric stimulation in men
Kistenmacher, A., Manneck, S., Wardzinski, E. K., Martens, J. C., Gohla, G., Melchert, U. H., Jauch‐Chara, K., & Oltmanns, K. M. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.03.011 · Cited by 32
Pancani, T., Anderson, K. L., Porter, N. M., & Thibault, O. (2011) · Cell Calcium · doi:10.1016/j.ceca.2011.09.002 · Cited by 25
Neuroenergetics: Astrocytes Have a Sweet Spot for Glucose
Pellerin, L. (2018) · Current Biology · doi:10.1016/j.cub.2018.09.042 · Cited by 25
Sublamina‐specific organization of the blood brain barrier in the mouse olfactory nerve layer
Beiersdorfer, A., Wolburg, H., Grawe, J., Scheller, A., Kirchhoff, F., & Lohr, C. (2019) · Glia · doi:10.1002/glia.23744 · Cited by 27
Lange, S. C., Winkler, U., Andresen, L. O., Byhrø, M., Waagepetersen, H. S., Hirrlinger, J., & Bak, L. K. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1651-9 · Cited by 24
Fernandez, A. M., Hernández-Garzón, E., Guerrero‐Gómez, D., Miranda‐Vizuete, A., & Torres‐Alemán, I. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.08.034 · Cited by 24
Aging is not equal across memory systems
Gardner, R. S., Newman, L. A., Mohler, E. G., Tunur, T., Gold, P. E., & Korol, D. L. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107232 · Cited by 24
Baud, M. O., Parafita, J., Nguyen, A., Magistretti, P. J., & Petit, J. (2016) · Journal of Sleep Research · doi:10.1111/jsr.12419 · Cited by 24
Effects of glucose load on cognitive functions in elderly people
van der Zwaluw, N. L., van de Rest, O., Kessels, R. P. C., & de Groot, C. P. G. M. (2015) · Nutrition Reviews · doi:10.1093/nutrit/nuu002 · Cited by 23
Bidirectional astrocytic GLUT1 activation by elevated extracellular K+
Fernández‐Moncada, I., Robles-Maldonado, D., Castro, P. A., Alegría, K., Epp, R., Ruminot, I., & Barros, L. F. (2020) · Glia · doi:10.1002/glia.23944 · Cited by 23
Lamtahri, R., Hazime, M., Gowing, E. K., Nagaraja, R. Y., Maucotel, J., Alasoadura, M., Quilichini, P., Lehongre, K., Lefranc, B., Gach, K., et al. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2255-20.2021 · Cited by 24
Self-citationMetabolic reprogramming of astrocytes: Emerging roles of lactate
Liu, Z., Guo, Y., Zhang, Y., Gao, Y., & Ning, B. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00776 · Cited by 22
Frontotemporal Dementia and Glucose Metabolism
Garrett, L. R., & Niccoli, T. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.812222 · Cited by 20
Newman, L. A., Scavuzzo, C. J., Gold, P. E., & Korol, D. L. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.12.001 · Cited by 21
Zhang, Z., Chen, W., Zhao, Y., & Yang, Y. A. (2018) · Neuroscience Bulletin · doi:10.1007/s12264-018-0229-3 · Cited by 20
Pan, S., Zhou, Y., Zuo, N., Jiao, R., Kong, L., & Pan, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.872375 · Cited by 20
Forgetfulness during aging: An integrated biology
Gold, P. E., & Korol, D. L. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.03.005 · Cited by 20
Romeo, R., Glotzbach, K., Scheller, A., & Faissner, A. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.567253 · Cited by 17
Breakdown and repair of metabolism in the aging brain
Shichkova, P., Coggan, J. S., Kanari, L., Boci, E., Favreau, C., Antonel, S., Keller, D. X., & Markram, H. (2025) · Frontiers in Science · doi:10.3389/fsci.2025.1441297 · Cited by 22
Computational singular perturbation analysis of brain lactate metabolism
Patsatzis, D. G., Tingas, E.-A., Goussis, D. A., & Sarathy, S. M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226094 · Cited by 19
Sun, Y., Yang, J., Hu, X., Gao, X., Li, Y., Yu, M., Liu, S., Lu, X., Jin, C., Wu, S., et al. (2017) · Archives of Toxicology · doi:10.1007/s00204-017-2148-x · Cited by 19
Longden, T. A., & Lederer, W. J. (2023) · The Journal of General Physiology · doi:10.1085/jgp.202313451 · Cited by 19
Roussel, T., Frydman, L., Bihan, D. L., & Ciobanu, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-40986-9 · Cited by 19
Zhu, X., Chen, W., Pinho, R. A., & Thirupathi, A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1598419 · Cited by 18
Endurance and Brain Glycogen: A Clue Toward Understanding Central Fatigue
Matsui, T., Soya, M., & Soya, H. (2019) · Advances in neurobiology · doi:10.1007/978-3-030-27480-1_11 · Cited by 15
Investigating KYNA production and kynurenergic manipulation on acute mouse brain slice preparations
Herédi, J., Cseh, E. K., Berkó, A. M., Veres, G., Zádori, D., Toldi, J., Kis, Z., Vécsei, L., Ono, E., & Gellért, L. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.12.014 · Cited by 15
Metabolism of Glycogen in Brain White Matter
Brown, A. M., Rich, L. R., & Ransom, B. R. (2019) · Advances in neurobiology · doi:10.1007/978-3-030-27480-1_7 · Cited by 15
Sayre, N. L., Chen, Y.-N., Sifuentes, M. M., Stoveken, B., & Lechleiter, J. D. (2014) · Advances in neurobiology · doi:10.1007/978-3-319-08894-5_7 · Cited by 15
Evaluation Methods for Facilitative Glucose Transport in Cells and Their Applications
Yamamoto, N., & Ashida, H. (2012) · Food Science and Technology Research · doi:10.3136/fstr.18.493 · Cited by 13
Biosynthesis of glycerol phosphate is associated with long-term potentiation in hippocampal neurons
Martano, G., Murru, L., Moretto, E., Gerosa, L., Garrone, G., Krogh, V., & Passafaro, M. (2016) · Metabolomics · doi:10.1007/s11306-016-1083-9 · Cited by 14
DiNuzzo, M., Giove, F., Maraviglia, B., & Mangia, S. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12164 · Cited by 12
Dienel, G. A., Cruz, N. F., Sokoloff, L., & Driscoll, B. F. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1650-x · Cited by 12
Piquet, J., Toussay, X., Hepp, R., Lerchundi, R., Douce, J. L., Faivre, É., Guiot, E., Bonvento, G., & Cauli, B. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00216 · Cited by 13
The consequences of neurodegenerative disease on neuron-astrocyte metabolic and redox interactions
Jiwaji, Z., & Hardingham, G. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106255 · Cited by 11
Prasad, S. K., Acharjee, A., Singh, V. V., Trigun, S. K., & Acharjee, P. (2024) · Metabolic Brain Disease · doi:10.1007/s11011-024-01407-7 · Cited by 11
Fan, Y., Wang, Z., & He, D. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220817140737 · Cited by 11
Tescarollo, F. C., Covolan, L., & Pellerin, L. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00246 · Cited by 11
Output Regulation and Function Optimization of Mitochondria in Eukaryotes
Zeng, M., He, Y. T., Du, H., Yang, J., & Wan, H. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.598112 · Cited by 10
Lactate rescues neuronal sodium homeostasis during impaired energy metabolism
Karus, C., Ziemens, D., & Rose, C. R. (2015) · Channels · doi:10.1080/19336950.2015.1050163 · Cited by 11
Involvement of brain metabolism in neurodevelopmental disorders
Kotchetkov, P., Blakeley, N., & Lacoste, B. (2023) · International review of neurobiology · doi:10.1016/bs.irn.2023.08.004 · Cited by 9
Zeng, M., He, Y. T., Zhou, H., Du, H., Shao, C., Yang, J., & Wan, H. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118766 · Cited by 9
Schurr, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26094429 · Cited by 12
Wang, T., Takikawa, Y., Sawara, K., Yoshida, Y., & Suzuki, K. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0806-1 · Cited by 9
Hexokinase and Glycolysis: Between Brain Cells Life and Death
da Mata, L. R. S., Santos, L., & César, M. C. (2023) · Current Chemical Biology · doi:10.2174/2212796817666230510095530 · Cited by 7
Mitochondrial dysfunction in PTSD: A mechanism to understand trauma susceptibility?
Amorim, F. E., Rye, C. S., & Milton, A. L. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06900-0 · Cited by 11
Scavuzzo, C. J., Newman, L. A., Gold, P. E., & Korol, D. L. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113385 · Cited by 7
Glial Excitatory Amino Acid Transporters and Glucose Incorporation
Aguilar, G. F. G., Alquisiras-Burgos, I., Espinoza-Rojo, M., & Aguilera, P. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-55769-4_13 · Cited by 7
Balancing the Contributions of Multiple Neural Systems During Learning and Memory
Gold, P. E. (2015) · Springer eBooks · doi:10.1007/978-3-319-15759-7_12 · Cited by 7
Neuronal activity-induced GLUT3 plasma translocation supports energy demands for memory acquisition
Wei, X., Zou, Z.-M., Yao, Z.-X., Teng, S.-W., Wei, X.-Y., Tang, W., Chen, X.-L., He, Y., & Chen, Z.-Y. (2025) · Communications Biology · doi:10.1038/s42003-025-09119-z · Cited by 8
Activity-dependent protein synthesis in neurons requires microglial-metabolic coupling
Adler, D. I., Martín‐Ávila, A., Cheng, E., Oliveira, M. M., Zhang, M., Evans, H. T., Yuan, D., Sam, R., Zhang, N., Sellés, M. C., et al. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.05.006 · Cited by 7
The Essential Role of Astrocytes in Neurodegeneration and Neuroprotection
Couselo, F. L., Saba, J., Carniglia, L., Durand, D., Lasaga, M., & Caruso, C. M. (2023) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/0118715273269881231012062255 · Cited by 6
Synaptic plasticity through a naturalistic lens
Piette, C., Gervasi, N., & Venance, L. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1250753 · Cited by 6
The role of astrocytes in ischemic stroke - mechanisms, functions and treatment
Wang, Y., Wang, D., Li, D., & Ma, Y. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1700564 · Cited by 5
Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy
Schneider, Y., Gauer, C., Andert, M., Hoffmann, A., Riemenschneider, M. J., Krebs, W., Chalmers, N., Lötzsch, C., Naumann, U. J., Xiang, W., et al. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-023-01699-3 · Cited by 7
Zhao, Y.-H., Linghu, T., Wang, Q., Qin, X., & Tian, J. (2025) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5c00667 · Cited by 5
Time-dependent changes in hippocampal and striatal glycogen long after maze training in male rats
Scavuzzo, C. J., Newman, L. A., Gold, P. E., & Korol, D. L. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107537 · Cited by 5
Modern Microscopic Approaches to Astrocytes
Morita, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065883 · Cited by 5
Axo-vascular coupling mediated by oligodendrocytesPreprint
Restrepo, A., Trevisiol, A., Restrepo-Arango, C., Depp, C., Sasmita, A. O., Keller, A., Tzvetanova, I. D., Hirrlinger, J., & Nave, K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.16.495900 · Cited by 6
The Astroglia Syncytial Theory of Consciousness
Robertson, J. M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125785 · Cited by 4
Sada, N., & Inoue, T. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780190497996.003.0029 · Cited by 4
Homeostasis to Allostasis: Prefrontal Astrocyte Roles in Cognitive Flexibility and Stress Biology
Wulaer, B., Holtz, M., & Nagai, J. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-64839-7_6 · Cited by 4
Glioma neuron symbiosis: a hypothesis
Schurr, A. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1646148 · Cited by 3
Imaging Guidance for Therapeutic Delivery: The Dawn of Neuroenergetics
Alambyan, V., Pace, J., Sukpornchairak, P., Yu, X., Alnimir, H., Tatton, R., Chitturu, G., Yarlagadda, A., & Ramos-Estébanez, C. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00843-4 · Cited by 3
Agas, A., Kalluru, J., Leiser, B., Garcia, R., Kataru, H., & Haorah, J. (2021) · Alcohol · doi:10.1016/j.alcohol.2021.04.003 · Cited by 2
Metabolic Plasticity of Astrocytes
Gorina, Y. V., Salmina, A. B., Erofeev, A. I., Can, Z., Bolshakova, A. V., Balaban, P. M., Борисович, Б. И., & Власова, О. Л. (2021) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093021060016 · Cited by 2
Glucose, glycolysis, and neurodegenerative disorders
Coelho, P., & Rego, A. C. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91704-9.00012-4 · Cited by 2
Role of Astrocytic Serine in Learning and Memory and its Implications in Alzheimer's Disease.
Maugard, M. (2018) · theses.fr (ABES) · doi:10.70675/2a0528d8zc687z43e6za9b4zfa45cdb5b6d9 · Cited by 1
Astroglial Connexins as Elements of Sleep-Wake Cycle Regulation and Dysfunction
Liu, X., & Giaume, C. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0974-2_18 · Cited by 1
Dynamic analysis of epileptic seizures caused by energy failure after ischemic stroke
Yu, Y., Yuan, Z., Li, J., & Wu, Y. (2023) · Chaos Solitons & Fractals · doi:10.1016/j.chaos.2023.114116 · Cited by 2
Hippocampal neural firing dynamics during sleep
Grosmark, A. (2014) · doi:10.7282/t3k072j1 · Cited by 1
Wang, T., Suzuki, K., Chiba, T., Kakisaka, K., & Takikawa, Y. (2021) · International Journal of Hepatology · doi:10.1155/2021/7615126 · Cited by 1
Microglia coordinate activity-dependent protein synthesis in neurons through metabolic couplingPreprint
Adler, D. I., Martín‐Ávila, A., Cheng, E., Oliveira, M. M., Zhang, M., Evans, H. T., Yuan, D., Sam, R., Zhang, N., Sellés, M. C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.29.685332 · Cited by 1
Mecanismos de regulación de la glucolisis en neuronas y su función en supervivencia celular
Rodríguez, P. R. (2013) · Gredos (University of Salamanca) · doi:10.14201/gredos.123044
EXPLORING THE ROLE OF MITOCHONDRIAL CHOLESTEROL IN NIEMANN-PICK TYPE C DISEASE
Kennedy, B. E. (2016) · DalSpace (Dalhousie University)
Hernández-Garzón, E., Fernandez, A. M., Pérez‐Alvarez, A., Mederos, S., Pérez‐Domper, P., Bascuñana, P., de la Rosa, R. F., Delgado, M., Pozo, M. A., Miranda‐Vizuete, A., et al. (2015) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/023556
COMMENTARY Modulation of Multiple Memory Systems: From Neurotransmitters to Metabolic Substrates
Gold, P. E., Newman, L. A., Scavuzzo, C. J., & Korol, D. L. (2013)
Glial Glutamate and Metabolic Transporters as a Target for Neurodegenerative Therapy and Biomarkers
Philips, T., & Sattler, R. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0974-2_4
The Central Role of Astrocytes in Neuroenergetics
Magistretti, P. J., & Pellerin, L. (2012) · doi:10.1093/med/9780199794591.003.0027
Sada, N., & Inoue, T. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197501207.003.0028 · Cited by 2
Perani, D. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.725446900.793537443
Advances in Oligodendrocyte Research
朱, 秀. (2022) · Advances in Clinical Medicine · doi:10.12677/acm.2022.1291261 · Cited by 1
Glial Cells During the Life Cycle
Walz, W. (2023) · Springer eBooks · doi:10.1007/978-3-031-48105-5_3
The Dual Role of Lactate in the Exercising Brain: Fueling Energy and Signaling Fatigue
Matsui, T., & Soya, H. (2025) · Advances in neurobiology · doi:10.1007/978-981-95-0066-6_11
Schneider, Y., Gauer, C., Andert, M., Hoffmann, A., Riemenschneider, M. J., Krebs, W., Chalmers, N., Lötzsch, C., Naumann, U. J., Xiang, W., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26658460
Schneider, Y., Gauer, C., Andert, M., Hoffmann, A., Riemenschneider, M. J., Krebs, W., Chalmers, N., Lötzsch, C., Naumann, U. J., Xiang, W., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26658454
Metadata
- Authors
- Chuquet, J., Quilichini, P., Nimchinsky, E. A., & Buzsáki, G.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2010-11-10
- Volume
- 30
- Issue
- 45
- Pages
- 15298-15303
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC2997269
- OpenAlex
- W2009966509
- Cited by
- 217
- References
- 42
- Citations by year
- 2026: 1 · 2025: 14 · 2024: 13 · 2023: 18 · 2022: 12 · 2021: 15 · 2020: 11 · 2019: 14 · 2018: 13 · 2017: 23 · 2016: 13 · 2015: 19 · 2014: 11 · 2013: 14 · 2012: 14
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, cc-by)
- Funders
- National Institute on Deafness and Other Communication Disorders (R01DC009947)
- National Institute of Neurological Disorders and Stroke (R01NS034994)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- astrocytes, neurons, glucose uptake, somatosensory cortex, barrel cortex, whisker stimulation, neuronal activation, two-photon microscopy, brain energy metabolism, functional neuroimaging
- MeSH terms
- Analysis of Variance, Animals, Astrocytes, Biological Transport, Glucose, Male, Neurons, Somatosensory Cortex, Vibrissae, Rats, Sprague-Dawley, Microscopy, Fluorescence, Multiphoton, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
