The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Selective Lengthening of the Cell Cycle in the Neurogenic Subpopulation of Neural Progenitor Cells during Mouse Brain Development
Open accessAbstract
During embryonic development of the mammalian brain, the average cell-cycle length of progenitor cells in the ventricular zone is known to increase. However, for any given region of the developing cortex and stage of neurogenesis, the length of the cell cycle is thought to be similar in the two coexisting subpopulations of progenitors [i.e., those undergoing (symmetric) proliferative divisions and those undergoing (either asymmetric or symmetric) neuron-generating divisions]. Using cumulative bromodeoxyuridine labeling of Tis21-green fluorescent protein knock-in mouse embryos, in which these two subpopulations of progenitors can be distinguished in vivo, we now show that at the onset as well as advanced stages of telencephalic neurogenesis, progenitors undergoing neuron-generating divisions are characterized by a significantly longer cell cycle than progenitors undergoing proliferative divisions. In addition, we find that the recently characterized neuronal progenitors dividing at the basal side of the ventricular zone and in the subventricular zone have a longer G 2 phase than those dividing at the ventricular surface. These findings are consistent with the hypothesis (Calegari and Huttner, 2003) that cell-cycle lengthening can causally contribute to neural progenitors switching from proliferative to neuron-generating divisions and may have important implications for the expansion of somatic stem cells in general.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
G1/S transition rates might be associated with cell decisions because symmetric divisions can have shorter G1/S transition times than asymmetric divisions.
“Interestingly, G1/S transition rates might be associated with these cell decisions as symmetric divisions can have shorter G1/S transition times than asymmetric divisions [93, 101].”
From The ASD Living Biology: from cell proliferation to clinical phenotype (2019) · cites this paper as [101]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Noctor, S. C., Martínez-Cerdeño, V., Ivic, L., & Kriegstein, A. R. (2004) · Nature Neuroscience · doi:10.1038/nn1172 · Cited by 2,229
Rakic, P. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93934-p · Cited by 1,047
Haubensak, W. E., Attardo, A., Denk, W. T., & Huttner, W. Β. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308600100 · Cited by 1,004
Self-citationAsymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells
Miyata, T., Kawaguchi, A., Saito, K., Kawano, M., Muto, T., & Ogawa, M. (2004) · Development · doi:10.1242/dev.01173 · Cited by 791
Characterization of CNS Precursor Subtypes and Radial Glia
Hartfuss, E., Galli, R., Heins, N., & Götz, M. (2001) · Developmental Biology · doi:10.1006/dbio.2000.9962 · Cited by 755
Nowakowski, R. S., Lewin, S. B., & Miller, M. W. (1989) · Journal of Neurocytology · doi:10.1007/bf01190834 · Cited by 755
Signalling, cell cycle and pluripotency in embryonic stem cells
Burdon, T., Smith, A. T., & Savatier, P. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(02)02352-8 · Cited by 727
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
Takahashi, T., Nowakowski, R. S., & Caviness, V. S. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06046.1995 · Cited by 673
Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model
Caviness, V. S., Takahashi, T., & Nowakowski, R. S. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93933-o · Cited by 566
Constructing the cerebral cortex: Neurogenesis and fate determination
McConnell, S. K. (1995) · Neuron · doi:10.1016/0896-6273(95)90168-x · Cited by 416
Radial glia diversity: A matter of cell fate
Kriegstein, A., & Götz, M. (2003) · Glia · doi:10.1002/glia.10250 · Cited by 376
Calegari, F., & Huttner, W. Β. (2003) · Journal of Cell Science · doi:10.1242/jcs.00825 · Cited by 367
Self-citationEarly ontogeny of the secondary proliferative population of the embryonic murine cerebral wall
Takahashi, T., Nowakowski, R. S., & Caviness, V. S. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06058.1995 · Cited by 219
Tirone, F. (2001) · Journal of Cellular Physiology · doi:10.1002/jcp.1062 · Cited by 214
Iacopetti, P., Michelini, M., Stuckmann, I., Oback, B. J., Aaku‐Saraste, E., & Huttner, W. Β. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.8.4639 · Cited by 207
Self-citationMartens, D. J., Tropepe, V., & van der Kooy, D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-03-01085.2000 · Cited by 148
Lukaszewicz, A. I., Savatier, P., Cortay, V., Kennedy, H., & Dehay, C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06610.2002 · Cited by 148
Hodge, R. D., D’Ercole, A. J., & OʼKusky, J. R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3246-04.2004 · Cited by 132
Glial Cell Lineages in the Rat Cerebral Cortex
Parnavelas, J. G. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7044 · Cited by 100
Local Homogeneity of Cell Cycle Length in Developing Mouse Cortex
Cai, L., Hayes, N. L., & Nowakowski, R. S. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-06-02079.1997 · Cited by 88
Dual Control of Neurogenesis by PC3 through Cell Cycle Inhibition and Induction of Math1
Canzoniere, D., Vecchioli, S. F., Conti, F., Ciotti, M. T., Tata, A. M., Augusti-Tocco, G., Mattei, E., Lakshmana, M. K., Krizhanovsky, V., Reeves, S. A., et al. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3860-03.2004 · Cited by 83
Reznikov, K. Y., & van der Kooy, D. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903600313 · Cited by 51
PC3 overexpression affects the pattern of cell division of rat cortical precursors
Malatesta, P., Götz, M., Barsacchi, G., Price, J., Zoncu, R., & Cremisi, F. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00224-5 · Cited by 41
Flagged first, then by citations
Cited by
Sorted by citations
The cell biology of neurogenesis
Götz, M., & Huttner, W. B. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1739 · Cited by 2,130
Self-citationTaverna, E., Götz, M., & Huttner, W. Β. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-101011-155801 · Cited by 780
Self-citationCell-cycle control and cortical development
Dehay, C., & Kennedy, H. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2097 · Cited by 655
Neural progenitors, neurogenesis and the evolution of the neocortex
Florio, M., & Huttner, W. Β. (2014) · Development · doi:10.1242/dev.090571 · Cited by 654
Self-citationThe timing of cortical neurogenesis is encoded within lineages of individual progenitor cells
Shen, Q., Wang, Y., Dimos, J. T., Fasano, C. A., Phoenix, T. N., Lemischka, I. R., Ivanova, N. B., Stifani, S., Morrisey, E. E., & Temple, S. (2006) · Nature Neuroscience · doi:10.1038/nn1694 · Cited by 636
Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic
Zhang, Z. G., & Chopp, M. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70061-4 · Cited by 596
Lange, C., Huttner, W. B., & Calegari, F. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.05.026 · Cited by 565
Self-citationAspm specifically maintains symmetric proliferative divisions of neuroepithelial cells
Fish, J. L., Kosodo, Y., Enard, W., Pääbo, S., & Huttner, W. B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604066103 · Cited by 421
Self-citationKowalczyk, T., Pontious, A., Englund, C., Daza, R. A. M., Bedogni, F., Hodge, R. D., Attardo, A., Bell, C., Huttner, W. Β., & Hevner, R. F. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn260 · Cited by 438
Self-citationProliferation control in neural stem and progenitor cells
Homem, C. C. F., Repic, M., & Knoblich, J. A. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn4021 · Cited by 393
Generating Neuronal Diversity in the Mammalian Cerebral Cortex
Lodato, S., & Arlotta, P. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125353 · Cited by 389
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface
Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch‐Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T., Huttner, W. Β., et al. (2006) · Nature Neuroscience · doi:10.1038/nn1744 · Cited by 396
Self-citationNeural stem and progenitor cells shorten S-phase on commitment to neuron production
Arai, Y., Pulvers, J. N., Haffner, C., Schilling, B., Nüsslein, I., Calegari, F., & Huttner, W. Β. (2011) · Nature Communications · doi:10.1038/ncomms1155 · Cited by 399
Self-citationDe Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development · doi:10.1242/dev.025080 · Cited by 343
Self-citationThe ASD Living Biology: from cell proliferation to clinical phenotype
Courchesne, E., Pramparo, T., Gazestani, V. H., Lombardo, M. V., Pierce, K., & Lewis, N. E. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0056-y · Cited by 333
Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells
Furutachi, S., Miya, H., Watanabe, T., Kawai, H., Yamasaki, N., Harada, Y., Imayoshi, I., Nelson, M., Nakayama, K. I., Hirabayashi, Y., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3989 · Cited by 329
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zonePreprint
Arnold, S. J., Huang, G., Cheung, A. F. P., Era, T., Nishikawa, S. I., Bikoff, E. K., Molnár, Z., Robertson, E. J., & Groszer, M. (2008) · Genes & Development · doi:10.1101/gad.475408 · Cited by 340
Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration
Wei, X., Fu, S., Li, H., Liu, Y., Wang, S., Feng, W., Yang, Y., Liu, X., Zeng, Y.-Y., Cheng, M., et al. (2022) · Science · doi:10.1126/science.abp9444 · Cited by 311
Neural stem cell systems: physiological players or in vitro entities?
Conti, L., & Cattaneo, E. F. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2761 · Cited by 330
The outer subventricular zone and primate-specific cortical complexification
Dehay, C., Kennedy, H., & Kosik, K. S. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.060 · Cited by 314
Cell Lineages and the Logic of Proliferative Control
Lander, A. D., Gokoffski, K. K., Wan, F. Y. M., Nie, Q. H., & Calof, A. L. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000015 · Cited by 294
Gabriel, E., Ramani, A., Karow, U., Gottardo, M., Natarajan, K., Gooi, L. M., Goranci-Buzhala, G., Krut, O., Peters, F., Nikolić, M., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2016.12.005 · Cited by 296
Huttner, W. Β., & Kosodo, Y. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.10.005 · Cited by 305
Self-citationAn early cell shape transition drives evolutionary expansion of the human forebrain
Benito-Kwiecinski, S. K., Giandomenico, S. L., Sutcliffe, M. A., Riis, E. S., Freire-Pritchett, P., Kelava, I., Wunderlich, S., Martin, U., Wray, G. A., McDole, K., et al. (2021) · Cell · doi:10.1016/j.cell.2021.02.050 · Cited by 272
Cell cycle control of mammalian neural stem cells: putting a speed limit on G1
Salomoni, P., & Calegari, F. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.01.006 · Cited by 289
Self-citationRadial glial cell heterogeneity—The source of diverse progeny in the CNS
Pinto, L., & GOTZ, M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.02.010 · Cited by 272
Ponti, G., Obernier, K., Guinto, C. D., Jose, L., Bonfanti, L., & Álvarez-Buylla, A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219563110 · Cited by 258
CPAP promotes timely cilium disassembly to maintain neural progenitor pool
Gabriel, E., Wason, A., Ramani, A., Gooi, L. M., Keller, P., Pozniakovsky, A., Poser, I., Noack, F., Telugu, N. S., Calegari, F., et al. (2016) · The EMBO Journal · doi:10.15252/embj.201593679 · Cited by 243
Self-citationRadial glia and neural stem cells
Malatesta, P., Appolloni, I., & Calzolari, F. (2007) · Cell and Tissue Research · doi:10.1007/s00441-007-0481-8 · Cited by 242
A primary microcephaly protein complex forms a ring around parental centrioles
Sir, J.-H., Barr, A. R., Nicholas, A. K., Carvalho, O. P., Khurshid, M., Sossick, A., Reichelt, S., D’Santos, C. S., Woods, C. G., & Gergely, F. V. (2011) · Nature Genetics · doi:10.1038/ng.971 · Cited by 226
Aprea, J., Prenninger, S., Dori, M., Ghosh, T., Monasor, L. S., Wessendorf, E., Zocher, S., Massalini, S., Alexopoulou, D., Lesche, M., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.245 · Cited by 221
Self-citationMNB/DYRK1A as a multiple regulator of neuronal development
Tejedor, F. J., & Hämmerle, B. (2011) · The FEBS Journal · doi:10.1111/j.1742-4658.2010.07954.x · Cited by 214
Molecular Control of Neurogenesis: A View from the Mammalian Cerebral CortexPreprint
Martynoga, B., Drechsel, D., & Guillemot, F. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008359 · Cited by 214
Soppa, U., Schumacher, J., Florencio Ortiz, V., Pasqualon, T., Tejedor, F., & Becker, W. (2014) · Cell Cycle · doi:10.4161/cc.29104 · Cited by 189
“For instance, a selective lengthening of G 1 phase appears to be pivotal for the switch to neurogenesis.(4) In particular, the antiproliferative CDK inhibitor p27 (CDKN1B) promotes cell cycle exit, whereas positive regulators of proliferation such as Cyclin D1 (CCND1) have the opposite effect.”
BackgroundCellular and molecular control of neurogenesis in the mammalian telencephalon
Guillemot, F. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.09.006 · Cited by 196
Baye, L. M., & Link, B. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2754-07.2007 · Cited by 187
Stancik, E. K., Navarro-Quiroga, I., Sellke, R., & Haydar, T. F. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.6131-09.2010 · Cited by 186
β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
Loulier, K., Lathia, J. D., Marthiens, V., Relucio, J. L. V., Mughal, M. R., Tang, S., Coksaygan, T., Hall, P. E., Chigurupati, S., Patton, B. L., et al. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000176 · Cited by 184
Neganova, I. E., Zhang, X., Atkinson, S. P., & Lako, M. (2008) · Oncogene · doi:10.1038/onc.2008.358 · Cited by 188
Specification of a Dopaminergic Phenotype from Adult Human Mesenchymal Stem Cells
Trzaska, K. A., Kuzhikandathil, E. V., & Rameshwar, P. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0212 · Cited by 181
Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells
Nelson, B. R., Hartman, B. H., Georgi, S. A., Lan, M. S., & Reh, T. A. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.01.001 · Cited by 174
Arai, Y., Funatsu, N., Numayama‐Tsuruta, K., Nomura, T., Nakamura, S., & Osumi, N. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2512-05.2005 · Cited by 174
Al-Kofahi, O., Radke, R. J., Goderie, S. K., Shen, Q., Temple, S., & Roysam, B. (2006) · Cell Cycle · doi:10.4161/cc.5.3.2426 · Cited by 172
Lengthened G1 Phase Indicates Differentiation Status in Human Embryonic Stem Cells
Calder, A. N., Roth-Albin, I., Bhatia, S., Pilquil, C., Lee, J., Bhatia, M., Levadoux‐Martin, M., McNicol, J. D., Russell, J., Collins, T., et al. (2012) · Stem Cells and Development · doi:10.1089/scd.2012.0168 · Cited by 160
An Adaptive Threshold in Mammalian Neocortical Evolution
Lewitus, É., Kelava, I., Kalinka, A. T., Tomančák, P., & Huttner, W. Β. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1002000 · Cited by 169
Self-citationAttardo, A., Calegari, F., Haubensak, W. E., Wilsch‐Bräuninger, M., & Huttner, W. Β. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002388 · Cited by 180
Self-citationMyosin II is required for interkinetic nuclear migration of neural progenitors
Schenk, J., Wilsch‐Bräuninger, M., Calegari, F., & Huttner, W. Β. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908928106 · Cited by 171
Self-citationFarkas, L. M., Haffner, C., Giger, T., Khaitovich, P., Nowick, K., Birchmeier, C., Pääbo, S., & Huttner, W. Β. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.020 · Cited by 162
Self-citationIschemic stroke and neurogenesis in the subventricular zone
Zhang, R. L., Zhang, Z. G., & Chopp, M. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.05.027 · Cited by 166
Predicting stem cell fate changes by differential cell cycle progression patterns
Roccio, M., Schmitter, D., Knobloch, M., Okawa, Y., Sage, D., & Lütolf, M. P. (2012) · Development · doi:10.1242/dev.086215 · Cited by 152
Small organelle, big responsibility: the role of centrosomes in development and disease
Chavali, P. L., Pütz, M., & Gergely, F. V. (2014) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2013.0468 · Cited by 154
Neurons derive from the more apical daughter in asymmetric divisions in the zebrafish neural tube
Alexandre, P., Reugels, A. M., Barker, D., Blanc, E., & Clarke, J. D. W. (2010) · Nature Neuroscience · doi:10.1038/nn.2547 · Cited by 159
Cell cycle regulation of proliferation versus differentiation in the central nervous system
Hardwick, L. J. A., Ali, F. R., Azzarelli, R., & Philpott, A. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1895-8 · Cited by 145
Hämmerle, B., Ulin, E., Guimera, J., Becker, W., Guillemot, F., & Tejedor, F. J. (2011) · Development · doi:10.1242/dev.066167 · Cited by 137
Comparative aspects of cortical neurogenesis in vertebrates
Cheung, A. F. P., Pollen, A. A., Tavare, A. N., DeProto, J., & Molnár, Z. (2007) · Journal of Anatomy · doi:10.1111/j.1469-7580.2007.00769.x · Cited by 137
Yang, C., Przyborski, S., Cooke, M. J., Zhang, X., Stewart, R., Anyfantis, G., Atkinson, S. P., Saretzki, G., Armstrong, L., & Lako, M. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0677 · Cited by 136
Brain Area-Specific Effect of TGF-β Signaling on Wnt-Dependent Neural Stem Cell Expansion
Falk, S., Wurdak, H., Ittner, L. M., Ille, F., Sumara, G., Schmid, M.-T., Draganova, K., Lang, K. S., Paratore, C., Levéen, P., et al. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.03.006 · Cited by 138
Waclaw, R. R., Wang, B., Pei, Z., Ehrman, L. A., & Campbell, K. (2009) · Neuron · doi:10.1016/j.neuron.2009.07.015 · Cited by 136
Richards, G. S., & Rentzsch, F. (2014) · Development · doi:10.1242/dev.112029 · Cited by 110
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Ratz, M., von Berlin, L., Larsson, L., Martin, M., Westholm, J. O., La Manno, G., Lundeberg, J., & Frisén, J. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01011-x · Cited by 127
Cyclin D2 Is Critical for Intermediate Progenitor Cell Proliferation in the Embryonic Cortex
Glickstein, S. B., Monaghan, J. A., Koeller, H. B., Jones, T. K., & Ross, M. E. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2284-09.2009 · Cited by 124
Proneural genes in neocortical development
Wilkinson, G., Dennis, D. J., & Schuurmans, C. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.08.029 · Cited by 122
MicroRNA 92b Controls the G1/S Checkpoint Gene p57 in Human Embryonic Stem Cells
Sengupta, S., Nie, J., Wagner, R. J., Yang, C., Stewart, R. M., & Thomson, J. A. (2009) · Stem Cells · doi:10.1002/stem.84 · Cited by 121
ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination
Capecchi, M. R., & Pozner, A. (2015) · Nature Communications · doi:10.1038/ncomms9763 · Cited by 115
Cubelos, B., Sebastián‐Serrano, Á., Kim, S., Moreno-Ortiz, C., Redondo, J. M., Walsh, C. A., & Nieto, M. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm199 · Cited by 122
Artegiani, B., Lindemann, D., & Calegari, F. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20102167 · Cited by 117
Self-citationTabata, H., Kanatani, S., & Nakajima, K. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn227 · Cited by 116
Bohačiaková, D., Mráz, M., Bárta, T., Plevová, K., Vinarský, V., Holubcová, Z., Jaroš, J., Dvořák, P., Pospı́šilová, Š., & Hampl, A. (2012) · Stem Cells · doi:10.1002/stem.1108 · Cited by 115
Meyer, H. M., Teles, J., Formosa-Jordan, P., Refahi, Y., San‐Bento, R., Ingram, G. C., Jönsson, H., Locke, J. C. W., & Roeder, A. (2017) · eLife · doi:10.7554/elife.19131 · Cited by 110
The tumor suppressor Pml regulates cell fate in the developing neocortex
Regad, T., Bellodi, C., Nicotera, P., & Salomoni, P. (2009) · Nature Neuroscience · doi:10.1038/nn.2251 · Cited by 119
Wilcock, A. C., Swedlow, J. R., & Storey, K. G. (2007) · Development · doi:10.1242/dev.002519 · Cited by 119
Probing human brain evolution and development in organoids
Giandomenico, S. L., & Lancaster, M. A. (2017) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2017.01.001 · Cited by 111
Krentz, N. A. J., Hoof, D. V., Li, Z., Watanabe, A., Tang, M., Nian, C., German, M. S., & Lynn, F. C. (2017) · Developmental Cell · doi:10.1016/j.devcel.2017.02.006 · Cited by 109
Wang, T., Stromberg, G. P., Whitney, J. T., Brower, N. W., Klymkowsky, M. W., & Parent, J. M. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.20984 · Cited by 107
Lim, I. K. (2006) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-006-0080-1 · Cited by 108
Siegenthaler, J. A., Tremper‐Wells, B., & Miller, M. W. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm209 · Cited by 100
Cortical progenitor biology: key features mediating proliferation versus differentiation
Uzquiano, A., Gladwyn-Ng, I. E., Nguyen, L., Reiner, O., Götz, M., Matsuzaki, F., & Francis, F. (2018) · Journal of Neurochemistry · doi:10.1111/jnc.14338 · Cited by 96
Mairet‐Coello, G., Tury, A., Buskirk, E. K. V., Robinson, K. R., Genestine, M., & DiCicco-Bloom, E. M. (2012) · Development · doi:10.1242/dev.067314 · Cited by 92
Najas, S., Arranz, J., Lochhead, P. A., Ashford, A. L., Oxley, D., Delabar, J. M., Cook, S. J., Barallobre, M. J., & Arbonés, M. L. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.01.010 · Cited by 92
Zhang, R. L., Zhang, Z. G., Lü, M., Wang, Y., Yang, J., & Chopp, M. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600237 · Cited by 94
Aneuploidy causes premature differentiation of neural and intestinal stem cells
Gogendeau, D., Siudeja, K., Gambarotto, D., Pennetier, C., Bardin, A. J., & Basto, R. (2015) · Nature Communications · doi:10.1038/ncomms9894 · Cited by 84
Le, Q., Yan, B., Yu, X., Li, Y., Song, H., Zhu, H., Hou, W., Ma, D., Wu, F., Zhou, Y., et al. (2017) · Nature Communications · doi:10.1038/ncomms15527 · Cited by 84
Loss of Cdk2 and Cdk4 Induces a Switch from Proliferation to Differentiation in Neural Stem Cells
Lim, S., & Kaldis, P. (2012) · Stem Cells · doi:10.1002/stem.1114 · Cited by 86
Nervous decision-making: to divide or differentiate
Hardwick, L. J. A., & Philpott, A. (2014) · Trends in Genetics · doi:10.1016/j.tig.2014.04.001 · Cited by 89
Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
Sachin Hebbar, C., Mesngon, M. T., Guillotte, A. M., Desai, B., Ayala, R., & Smith, D. S. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200803071 · Cited by 86
Regeneration of Zebrafish CNS: Adult Neurogenesis
Ghosh, S., & Hui, S. P. (2016) · Neural Plasticity · doi:10.1155/2016/5815439 · Cited by 90
Time is of the essence: the molecular mechanisms of primary microcephalyPreprint
Phan, T. P., & Holland, A. J. (2021) · Genes & Development · doi:10.1101/gad.348866.121 · Cited by 84
Albors, A. R., Tazaki, A., Rost, F., Nowoshilow, S., Chara, O., & Tanaka, E. M. (2015) · eLife · doi:10.7554/elife.10230 · Cited by 83
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules
Gai, M., Bianchi, F. T., Vagnoni, C., Vernı̀, F., Bonaccorsi, S., Pasquero, S., Berto, G. E., Sgrò, F., Chiotto, A. M. A., Annaratone, L., et al. (2016) · EMBO Reports · doi:10.15252/embr.201541823 · Cited by 86
Self-citationVecchioli, S. F., Saraulli, D., Costanzi, M., Leonardi, L., Cinà, I., Micheli, L., Nutini, M., Longone, P., Oh, S. P., Cestari, V., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008339 · Cited by 86
Lacomme, M., Liaubet, L., Pituello, F., & Bel-Vialar, S. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.06745-11 · Cited by 96
Blazejewski, S. M., Bennison, S. A., Smith, T. H., & Toyo‐oka, K. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00080 · Cited by 80
Molecular and cellular evolution of corticogenesis in amniotes
Cárdenas, A., & Borrell, V. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03315-x · Cited by 86
Proneural bHLH Genes in Development and Disease
Huang, C., Chan, J. A.-W., & Schuurmans, C. J. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-405943-6.00002-6 · Cited by 80
Stolp, H. B., Neuhaus, A. A., Sundramoorthi, R., & Molnár, Z. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00050 · Cited by 91
Mechanisms of brain evolution: Regulation of neural progenitor cell diversity and cell cycle length
Borrell, V., & Calegari, F. (2014) · Neuroscience Research · doi:10.1016/j.neures.2014.04.004 · Cited by 82
Self-citationWnt signaling and neural stem cells: caught in the Wnt web
Michaelidis, T. M., & Lie, D. C. (2007) · Cell and Tissue Research · doi:10.1007/s00441-007-0476-5 · Cited by 84
ATR maintains select progenitors during nervous system development
Lee, Y., Shull, E. R. P., Frappart, P., Katyal, S., Enriquez-Rios, V. D., Zhao, J., Russell, H. R., Brown, E. J., & McKinnon, P. J. (2012) · The EMBO Journal · doi:10.1038/emboj.2011.493 · Cited by 78
Bertacchi, M., Romano, A. L., Loubat, A., Mau‐Them, F. T., Willems, M., Faivre, L. O., Kien, P. K. V., Perrin, L., Devillard, F., Sorlin, A., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2019104163 · Cited by 74
Barton, K., & Levine, E. M. (2008) · Developmental Dynamics · doi:10.1002/dvdy.21449 · Cited by 79
Metadata
- Authors
- Calegari, F., Haubensak, W., Haffner, C., & Huttner, W. B.
- Affiliations
- Max Planck Institute of Molecular Cell Biology and Genetics (DE)
- California Institute of Technology (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2005-07-13
- Volume
- 25
- Issue
- 28
- Pages
- 6533-6538
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6725437
- OpenAlex
- W1999970417
- Cited by
- 396
- References
- 23
- Citations by year
- 2026: 10 · 2025: 16 · 2024: 11 · 2023: 11 · 2022: 16 · 2021: 19 · 2020: 25 · 2019: 19 · 2018: 22 · 2017: 18 · 2016: 17 · 2015: 23 · 2014: 23 · 2013: 15 · 2012: 24
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft (SPP1109)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- neural progenitor cells, neurogenesis, telencephalic development, ventricular zone, subventricular zone, G2 phase, TIS21, BrdU labeling, mouse embryo, adult stem cells
- MeSH terms
- Animals, Brain, Cell Cycle, Cell Differentiation, Cell Division, Gestational Age, Mice, Inbred C57BL, Neuroglia, Neurons, Recombinant Fusion Proteins, Stem Cells, Telencephalon, Time Factors, Genes, Tumor Suppressor, Immediate-Early Proteins, Genes, Reporter, Gene Expression Regulation, Developmental, Tumor Suppressor Proteins, Green Fluorescent Proteins, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
