CoChat
Sign Up
Cited by 104

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction

Vaz‐Silva, João, Gomes, Patrícia, Jin, Qi, Zhu, Mei, Zhuravleva, Viktoriya, Quintremil, Sebastian, Meira, Torcato, Silva, Joana, Dioli, Chrysoula, Soares‐Cunha, Carina, Daskalakis, Nikolaos P, Sousa, Nuno, Sotiropoulos, Ioannis, Waites, Clarissa L·2018·The EMBO Journal
DOI 10.15252/embj.201899084

Published version of a preprint

Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.15252/embj.201899084

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 52

  1. de Araujo ME, Huber LA, Stasyk T (2008) Isolation of endocytic organelles by density gradient centrifugation. Methods Mol Biol 424: 317–331 · DOI
  2. Caballero B, Wang Y, Diaz A, Tasset I, Juste YR, Stiller B, Mandelkow EM, Mandelkow E, Cuervo AM (2017) Interplay of pathogenic forms of human tau with different autophagic pathways. Aging Cell 17: e12692 · DOI · Paper page
  3. Chesser AS, Pritchard SM, Johnson GV (2013) Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease. Front Neurol 4: 122 · DOI · Paper page
  4. Clayton EL, Mizielinska S, Edgar JR, Nielsen TT, Marshall S, Norona FE, Robbins M, Damirji H, Holm IE, Johannsen P, Nielsen JE, Asante EA, Collinge J, FReJA Consortium, Isaacs AM (2015) Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathol 130: 511–523 · DOI · Paper page
  5. Dioli C, Patricio P, Trindade R, Pinto LG, Silva JM, Morais M, Ferreiro E, Borges S, Mateus‐Pinheiro A, Rodrigues AJ, Sousa N, Bessa JM, Pinto L, Sotiropoulos I (2017) Tau‐dependent suppression of adult neurogenesis in the stressed hippocampus. Mol Psychiatry 22: 1110–1118 · DOI
  6. Fernandes AC, Uytterhoeven V, Kuenen S, Wang YC, Slabbaert JR, Swerts J, Kasprowicz J, Aerts S, Verstreken P (2014) Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky‐induced neurodegeneration. J Cell Biol 207: 453–462 · DOI
  7. Frankel EB, Audhya A (2017) ESCRT‐dependent cargo sorting at multivesicular endosomes. Semin Cell Dev Biol 74: 4–10 · DOI
  8. Georgieva ER, Xiao S, Borbat PP, Freed JH, Eliezer D (2014) Tau binds to lipid membrane surfaces via short amphipathic helices located in its microtubule‐binding repeats. Biophys J 107: 1441–1452 · DOI
  9. Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM (2006) Glucocorticoids increase amyloid‐beta and tau pathology in a mouse model of Alzheimer's disease. J Neurosci 26: 9047–9056 · DOI · Paper page
  10. Guo T, Noble W, Hanger DP (2017) Roles of tau protein in health and disease. Acta Neuropathol 133: 665–704 · DOI · Paper page
  11. Hamano T, Gendron TF, Causevic E, Yen SH, Lin WL, Isidoro C, Deture M, Ko LW (2008) Autophagic‐lysosomal perturbation enhances tau aggregation in transfectants with induced wild‐type tau expression. Eur J Neurosci 27: 1119–1130 · DOI · Paper page
  12. Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, Pitstick R, Carlson GA, Lanier LM, Yuan LL, Ashe KH, Liao D (2010) Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 68: 1067–1081 · DOI · Paper page
  13. Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, Wolfing H, Chieng BC, Christie MJ, Napier IA, Eckert A, Staufenbiel M, Hardeman E, Gotz J (2010) Dendritic function of tau mediates amyloid‐beta toxicity in Alzheimer's disease mouse models. Cell 142: 387–397 · DOI · Paper page
  14. Johansson L, Guo X, Waern M, Ostling S, Gustafson D, Bengtsson C, Skoog I (2010) Midlife psychological stress and risk of dementia: a 35‐year longitudinal population study. Brain 133: 2217–2224 · DOI
  15. Kett LR, Dauer WT (2016) Endolysosomal dysfunction in Parkinson's disease: recent developments and future challenges. Mov Disord 31: 1433–1443 · DOI
  16. Khanna MR, Kovalevich J, Lee VM, Trojanowski JQ, Brunden KR (2016) Therapeutic strategies for the treatment of tauopathies: hopes and challenges. Alzheimers Dement 12: 1051–1065 · DOI
  17. Kimura T, Yamashita S, Fukuda T, Park JM, Murayama M, Mizoroki T, Yoshiike Y, Sahara N, Takashima A (2007) Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild‐type human tau. EMBO J 26: 5143–5152 · DOI · Paper page
  18. Kobayashi S, Tanaka T, Soeda Y, Almeida OFX, Takashima A (2017) Local somatodendritic translation and hyperphosphorylation of tau protein triggered by AMPA and NMDA receptor stimulation. EBioMedicine 20: 120–126 · DOI
  19. Kontaxi C, Piccardo P, Gill AC (2017) Lysine‐directed post‐translational modifications of tau protein in Alzheimer's disease and related tauopathies. Front Mol Biosci 4: 56 · DOI · Paper page
  20. Lee MJ, Lee JH, Rubinsztein DC (2013) Tau degradation: the ubiquitin‐proteasome system versus the autophagy‐lysosome system. Prog Neurobiol 105: 49–59 · DOI · Paper page
  21. Lopes S, Lopes A, Pinto V, Guimaraes MR, Sardinha VM, Duarte‐Silva S, Pinheiro S, Pizarro J, Oliveira JF, Sousa N, Leite‐Almeida H, Sotiropoulos I (2016a) Absence of Tau triggers age‐dependent sciatic nerve morphofunctional deficits and motor impairment. Aging Cell 15: 208–216 · DOI
  22. Lopes S, Teplytska L, Vaz‐Silva J, Dioli C, Trindade R, Morais M, Webhofer C, Maccarrone G, Almeida OF, Turck CW, Sousa N, Sotiropoulos I, Filiou MD (2016b) Tau deletion prevents stress‐induced dendritic atrophy in prefrontal cortex: role of synaptic mitochondria. Cereb Cortex 27: 2580–2591
  23. Lopes S, Vaz‐Silva J, Pinto V, Dalla C, Kokras N, Bedenk B, Mack N, Czisch M, Almeida OF, Sousa N, Sotiropoulos I (2016c) Tau protein is essential for stress‐induced brain pathology. Proc Natl Acad Sci USA 113: E3755–E3763 · DOI
  24. Machado A, Herrera AJ, de Pablos RM, Espinosa‐Oliva AM, Sarmiento M, Ayala A, Venero JL, Santiago M, Villaran RF, Delgado‐Cortes MJ, Arguelles S, Cano J (2014) Chronic stress as a risk factor for Alzheimer's disease. Rev Neurosci 25: 785–804 · DOI
  25. Maminska A, Bartosik A, Banach‐Orlowska M, Pilecka I, Jastrzebski K, Zdzalik‐Bielecka D, Castanon I, Poulain M, Neyen C, Wolinska‐Niziol L, Torun A, Szymanska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Furthauer M, Gonzalez‐Gaitan M, Miaczynska M (2016) ESCRT proteins restrict constitutive NF‐kappaB signaling by trafficking cytokine receptors. Sci Signal 9: ra8 · DOI · Paper page
  26. Mondragon‐Rodriguez S, Trillaud‐Doppia E, Dudilot A, Bourgeois C, Lauzon M, Leclerc N, Boehm J (2012) Interaction of endogenous tau protein with synaptic proteins is regulated by N‐methyl‐D‐aspartate receptor‐dependent tau phosphorylation. J Biol Chem 287: 32040–32053 · DOI · Paper page
  27. Nixon RA, Yang DS (2011) Autophagy failure in Alzheimer's disease–locating the primary defect. Neurobiol Dis 43: 38–45 · DOI · Paper page
  28. Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N (2016) ESCRT‐0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress‐mediated neurodegeneration via apoptotic and necroptotic pathways. Sci Rep 6: 24997 · DOI
  29. Pallas‐Bazarra N, Jurado‐Arjona J, Navarrete M, Esteban JA, Hernandez F, Avila J, Llorens‐Martin M (2016) Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis. EMBO J 35: 1417–1436 · DOI · Paper page
  30. Pinheiro S, Silva J, Mota C, Vaz‐Silva J, Veloso A, Pinto V, Sousa N, Cerqueira J, Sotiropoulos I (2015) Tau mislocation in glucocorticoid‐triggered hippocampal pathology. Mol Neurobiol 53: 4745–4753 · DOI
  31. Pooler AM, Hanger DP (2010) Functional implications of the association of tau with the plasma membrane. Biochem Soc Trans 38: 1012–1015 · DOI
  32. Raiborg C, Stenmark H (2009) The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature 458: 445–452 · DOI · Paper page
  33. Rivero‐Rios P, Gomez‐Suaga P, Fernandez B, Madero‐Perez J, Schwab AJ, Ebert AD, Hilfiker S (2015) Alterations in late endocytic trafficking related to the pathobiology of LRRK2‐linked Parkinson's disease. Biochem Soc Trans 43: 390–395 · DOI
  34. Roberson ED, Scearce‐Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L (2007) Reducing endogenous tau ameliorates amyloid beta‐induced deficits in an Alzheimer's disease mouse model. Science 316: 750–754 · DOI · Paper page
  35. Ross JA, Gliebus G, Van Bockstaele EJ (2017) Stress induced neural reorganization: a conceptual framework linking depression and Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 85: 136–151 · DOI
  36. Sahu R, Kaushik S, Clement CC, Cannizzo ES, Scharf B, Follenzi A, Potolicchio I, Nieves E, Cuervo AM, Santambrogio L (2011) Microautophagy of cytosolic proteins by late endosomes. Dev Cell 20: 131–139 · DOI · Paper page
  37. Sheehan P, Zhu M, Beskow A, Vollmer C, Waites CL (2016) Activity‐Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway. J Neurosci 36: 8668–8686 · DOI
  38. Small SA, Simoes‐Spassov S, Mayeux R, Petsko GA (2017) Endosomal traffick jams represent a pathogenic hub and therapeutic target in Alzheimer's disease. Trends Neurosci 40: 592–602 · DOI · Paper page
  39. Sotiropoulos I, Catania C, Riedemann T, Fry JP, Breen KC, Michaelidis TM, Almeida OF (2008a) Glucocorticoids trigger Alzheimer disease‐like pathobiochemistry in rat neuronal cells expressing human tau. J Neurochem 107: 385–397 · DOI · Paper page
  40. Sotiropoulos I, Cerqueira JJ, Catania C, Takashima A, Sousa N, Almeida OF (2008b) Stress and glucocorticoid footprints in the brain‐the path from depression to Alzheimer's disease. Neurosci Biobehav Rev 32: 1161–1173 · DOI
  41. Sotiropoulos I, Catania C, Pinto LG, Silva R, Pollerberg GE, Takashima A, Sousa N, Almeida OF (2011) Stress acts cumulatively to precipitate Alzheimer's disease‐like tau pathology and cognitive deficits. J Neurosci 31: 7840–7847 · DOI
  42. Sotiropoulos I, Galas MC, Silva JM, Skoulakis E, Wegmann S, Maina MB, Blum D, Sayas CL, Mandelkow EM, Mandelkow E, Spillantini MG, Sousa N, Avila J, Medina M, Mudher A, Buee L (2017) Atypical, non‐standard functions of the microtubule associated Tau protein. Acta Neuropathol Commun 5: 91 · DOI
  43. Sousa N, Almeida OF (2012) Disconnection and reconnection: the morphological basis of (mal)adaptation to stress. Trends Neurosci 35: 742–751 · DOI · Paper page
  44. Subach FV, Subach OM, Gundorov IS, Morozova KS, Piatkevich KD, Cuervo AM, Verkhusha VV (2009) Monomeric fluorescent timers that change color from blue to red report on cellular trafficking. Nat Chem Biol 5: 118–126 · DOI
  45. Suzuki K, Parker CC, Pentchev PG, Katz D, Ghetti B, D'Agostino AN, Carstea ED (1995) Neurofibrillary tangles in Niemann‐Pick disease type C. Acta Neuropathol 89: 227–238 · DOI
  46. Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, Finkbeiner S, Cui B, Mucke L (2010) Tau reduction prevents Abeta‐induced defects in axonal transport. Science 330: 198 · DOI · Paper page
  47. Watson JA, Bhattacharyya BJ, Vaden JH, Wilson JA, Icyuz M, Howard AD, Phillips E, DeSilva TM, Siegal GP, Bean AJ, King GD, Phillips SE, Miller RJ, Wilson SM (2015) Motor and sensory deficits in the teetering mice result from mutation of the ESCRT component HGS. PLoS Genet 11: e1005290 · DOI
  48. Yevshin I, Sharipov R, Valeev T, Kel A, Kolpakov F (2017) GTRD: a database of transcription factor binding sites identified by ChIP‐seq experiments. Nucleic Acids Res 45: D61–D67 · DOI
  49. Yin Y, Gao D, Wang Y, Wang ZH, Wang X, Ye J, Wu D, Fang L, Pi G, Yang Y, Wang XC, Lu C, Ye K, Wang JZ (2016) Tau accumulation induces synaptic impairment and memory deficit by calcineurin‐mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci USA 113: E3773–E3781 · DOI
  50. Zhang JY, Liu SJ, Li HL, Wang JZ (2005) Microtubule‐associated protein tau is a substrate of ATP/Mg(2+)‐dependent proteasome protease system. J Neural Transm (Vienna) 112: 547–555 · DOI
  51. Zhang Y, Chen X, Zhao Y, Ponnusamy M, Liu Y (2017a) The role of ubiquitin proteasomal system and autophagy‐lysosome pathway in Alzheimer's disease. Rev Neurosci 28: 861–868 · DOI
  52. Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE, FReJA Consortium et al (2017b) Patient iPSC‐derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B. Stem Cell Reports 8: 648–658 · DOI

Cited by

Sorted by citations

Metadata

Authors
Vaz‐Silva, J., Gomes, P., Jin, Q., Zhu, M., Zhuravleva, V., Quintremil, S., Meira, T., Silva, J., Dioli, C., Soares‐Cunha, C., Daskalakis, N. P., Sousa, N., Sotiropoulos, I., & Waites, C. L.
ORCID
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
2018-08-30
Volume
37
Issue
20
ISSN
  • 0261-4189
  • 1460-2075
DOI
10.15252/embj.201899084
Cited by
104
References
4
Language
en
Licence
Funders
  • Portuguese North Regional Operational Program (ON.2) under the National Strategic Reference Framework (QREN), through the European Regional Development Fund
  • HHS | NIH | National Institute of Neurological Disorders and Stroke (R01NS080967)
  • HHS | NIH | National Institute of Mental Health (R21MH104803)
  • MEC | Fundação para a Ciência e a Tecnologia (PD/BD/105938/2014, PD/BD/113700/2015, IF/01799/2013, PEst‐C/SAU/LA0026/2013)
  • EC | European Regional Development Fund (FCOMP‐01‐0124‐FEDER‐037298, NORTE‐01‐0145‐FEDER‐000013)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review