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Pol γ is the only replicative polymerase known to function in mitochondrial DNA replication and repair.
“Of the 17 human cellular DNA polymerases, polymerase gamma (Pol γ) is the only replicative polymerase known to function in mitochondrial DNA replication and repair (Bebenek and Kunkel, 2004; Ropp and Copeland, 1996; Sweasy et al., 2006).”
From Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases (2017) · cites this paper as Bebenek and Kunkel, 2004
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- Authors
- Bebenek, K., & Kunkel, T. A.
- Affiliations
- National Institutes of Health (US)
- ORCID
- Kunkel, Thomas A.
- Venue
- Advances in Protein Chemistry
- Publisher
- Elsevier
- Published
- 2004
- Volume
- 69
- Pages
- 137-165
- ISSN
- 0065-3233 (ISSN-L)
- OpenAlex
- W1522752776
- Semantic Scholar
- 74ed72b85e259d72dd6881d1e8ebfb5620638e5a
- Cited by
- 258
- References
- 111
- Citations by year
- 2026: 8 · 2025: 2 · 2024: 6 · 2023: 5 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 5 · 2018: 10 · 2017: 11 · 2016: 8 · 2015: 3 · 2014: 20 · 2013: 14 · 2012: 18
- FWCI
- 22.94
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in protein chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Health Sciences › Medicine › Pathology and Forensic Medicine › Genetic factors in colorectal cancer
- Keywords
- DNA polymerase, DNA repair, DNA replication, nucleotide excision repair, base excision repair, interstrand crosslink repair, genome stability, immune system development, genetic diversity
- MeSH terms
- Animals, DNA Damage, DNA-Directed DNA Polymerase, DNA Repair, DNA Replication, Humans, Immune System
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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