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Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η

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Human DNA Polymerase η Is Required for Common Fragile Site Stability during Unperturbed DNA Replication

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Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers

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UV-B Radiation Induces Epithelial Tumors in Mice Lacking DNA Polymerase η and Mesenchymal Tumors in Mice Deficient for DNA Polymerase ι

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Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes

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Translesion DNA Synthesis and Carcinogenesis

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In vivo Metabolic Imaging of Insulin with Multiphoton Fluorescence of Human Insulin–Au Nanodots

Liu, C., Liu, T., Hsieh, T., Liu, H., Chen, Y., Tsai, C., Chen, H., Lin, J., Hsu, R., Wang, T., et al. (2012) · Small · doi:10.1002/smll.201201887 · Cited by 18 · see citing works

New Templated Ostwald Ripening Process of Mesostructured FeOOH for Third‐Harmonic Generation Bioimaging

Lee, C., Wu, P., Hsu, I., Liu, T., Chong, W., Wu, C., Hsieh, T., Guo, L., Tsao, Y., Wu, P., et al. (2019) · Small · doi:10.1002/smll.201805086 · Cited by 17 · see citing works

DNA Polymerase Eta Participates in the Mutagenic Bypass of Adducts Induced by Benzo[a]pyrene Diol Epoxide in Mammalian Cells

Klarer, A. C., Stallons, L. J., Burke, T. J., Skaggs, R. L., & McGregor, W. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039596 · Cited by 16 · see citing works

Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure

Tanoue, Y., Toyoda, T., Sun, J., Mustofa, M. K., Tateishi, C., Endo, S., Motoyama, N., Araki, K., Wu, D., Okuno, Y., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.05.015 · Cited by 15 · see citing works

Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis

Peddu, C., Zhang, S., Zhao, H. L., Wong, A., Lee, E. Y. C., Lee, M., & Zhang, Z. (2018) · iScience · doi:10.1016/j.isci.2018.07.009 · Cited by 13 · see citing works

Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta

Nicolay, N. H., Carter, R., Hatch, S. B., Schultz, N., Prevo, R., McKenna, W. G., Helleday, T., & Sharma, R. A. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs239 · Cited by 13 · see citing works

Novel DNA Polymerases and Novel Genotoxicity Assays

Nohmi, T. (2007) · Genes and Environment · doi:10.3123/jemsge.29.75 · Cited by 12 · see citing works

Adenovirus mediated transduction of the human DNA polymerase eta cDNA

Lima-Bessa, K. M., Chiganças, V., Stary, A., Kannouche, P., Sarasin, A., Armelini, M. G., de Fátima Jacysyn, J., Amarante-Mendes, G. P., Cordeiro-Stone, M., Cleaver, J. E., et al. (2006) · DNA Repair · doi:10.1016/j.dnarep.2006.05.037 · Cited by 11 · see citing works

Detrimental effects of UV‐B radiation in a xeroderma pigmentosum‐variant cell line

Herman, K. N., Toffton, S. M., & McCulloch, S. D. (2014) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21857 · Cited by 10 · see citing works

Xeroderma Pigmentosum Variant, XP-V: Its Product and Biological Roles

Masutani, C., Hanaoka, F., & Ahmad, S. (2008) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-09599-8_10 · Cited by 10 · see citing works

Impact of Chemical Adducts on Translesion Synthesis in Replicative and Bypass DNA Polymerases: From Structure to Function

Eoff, R. L., Egli, M., & Guengerich, F. P. (2010) · Wiley eBooks · doi:10.1002/9783527630110.ch13 · Cited by 9 · see citing works

Nontraditional Roles of DNA Polymerase Eta Support Genome Duplication and Stability

Eckert, K. A. (2023) · Genes · doi:10.3390/genes14010175 · Cited by 9 · see citing works

Mouse models of DNA polymerases

Menezes, M. R., & Sweasy, J. B. (2012) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21731 · Cited by 9 · see citing works

Nontranscriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis

Daitoku, H., Kaneko, Y., Yoshimochi, K., Matsumoto, K., Araoi, S., Sakamaki, J.-I., Takahashi, Y., & Fukamizu, A. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00265-16 · Cited by 9 · see citing works

The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG ‐related disorders

Gilea, A. I., Magistrati, M., Notaroberto, I., Tiso, N., Dallabona, C., & Baruffini, E. (2023) · IUBMB Life · doi:10.1002/iub.2770 · Cited by 8 · see citing works

Human TLS DNA polymerase: saviors or threats under replication stress?

Rajpurohit, Y. S., Lal, M., Sharma, D. K., & Soni, I. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05291-2 · Cited by 6 · see citing works

Kinetic Approaches to Understanding the Mechanisms of Fidelity of the Herpes Simplex Virus Type 1 DNA Polymerase

Zhu, Y., Stroud, J., Song, L., & Parris, D. S. (2010) · Journal of Nucleic Acids · doi:10.4061/2010/631595 · Cited by 6 · see citing works

Chemical induced alterations in p53 signaling

Högberg, J., Silins, I., & Stenius, U. (2009) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-7643-8336-7_7 · Cited by 6 · see citing works

Bypass DNA Polymerases

Choi, J., Eoff, R. L., & Guengerich, F. P. (2010) · Humana Press eBooks · doi:10.1007/978-1-61737-995-6_16 · Cited by 5 · see citing works

Genetically Modified Animal Models

Chaible, L. M., Kinoshita, D., Corat, M. A. F., & Dagli, M. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809468-6.00027-9 · Cited by 5 · see citing works

Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells

Yeom, M., Hong, J., Shin, J., Lee, Y., Guengerich, F. P., & Choi, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065198 · Cited by 4 · see citing works

Manganese Is a Strong Specific Activator of the RNA Synthetic Activity of Human Polη

Bálint, É., & Unk, I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010230 · Cited by 4 · see citing works

Environmental Stress and

Dna, L.-B., & Nohmi, T. (2006) · Cited by 4 · see citing works

Translesion DNA Synthesis and Damage Tolerance Pathways

Masuda, Y., Hanaoka, F., & Masutani, C. (2016) · Springer eBooks · doi:10.1007/978-4-431-55873-6_11 · Cited by 3 · see citing works

Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA

O’Flaherty, D. K., Guengerich, F. P., Egli, M., & Wilds, C. J. (2015) · Biochemistry · doi:10.1021/acs.biochem.5b01078 · Cited by 3 · see citing works

Genetically Modified Animal Models

Chaible, L. M., Kinoshita, D., Corat, M. A. F., & Dagli, M. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-415894-8.00033-6 · Cited by 3 · see citing works

Roles of RAD18 in DNA replication and post-replication repair (PRR)

Kovalchuk, I. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00016-7 · Cited by 2 · see citing works

Xeroderma pigmentosum variant: Complementary molecular approaches to detect a 13 base pair deletion in the DNA polymerase eta gene

Hentosh, P., Benjamin, T., Hall, L., Leap, S., Loescher, J., Poyner, E. F. M., Sundin, T., Whittle, M., Wilkinson, S., & Peffley, D. M. (2011) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2011.05.004 · Cited by 2 · see citing works

Roles of RAD18 in DNA Replication and Postreplication Repair

Vaziri, C., Tateishi, S., Mutter‐Rottmayer, E., & Gao, Y. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803309-8.00016-1 · Cited by 2 · see citing works

Translesion DNA Synthesis

Masutani, C., & Hanaoka, F. (2018) · Springer eBooks · doi:10.1007/978-981-10-6722-8_12 · Cited by 1 · see citing works

Xeroderma Pigmentosum and the DNA Damage Response to Ultraviolet Light

Cleaver, J. E. (2016) · Springer eBooks · doi:10.1007/978-1-59745-458-2_24 · Cited by 1 · see citing works

A large scale genomic screen reveals mechanisms of yeast postreplication repair in Saccharomyces cerevisiae

Ball, L. G. (2011) · University Library - University of Saskatchewan (University of Saskatchewan) · Cited by 1 · see citing works

Human DNA Polymerase η and Its Regulatory Mechanisms

Masutani, C. (2012) · Genes and Environment · doi:10.3123/jemsge.34.63

DNA Damage Tolerance and Translesion Synthesis

Lehmann, A. R. (2009) · Springer eBooks · doi:10.1007/978-90-481-2561-6_10

Screening for Suppression of Inflammatory Responses Against UVB-Induced DNA Damage in Skin Cells Based on Natural Plant Extract Enhances DNA Repair-Related Polymerase Activity

Shiratake, S., Onodera, T., Sakamoto, Y., Nakahara, T., Iwahashi, H., & Mizushina, Y. (2015) · InTech eBooks · doi:10.5772/60483

Cell cycle: mechanisms of control and dysregulation in cancer

Knudsen, E. S., Bourgo, R. J., Gosnell, E. L., Dean, J. L., & McClendon, A. K. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139046947.039

Studies on Molecular Basis for FOXO1-DNA Damage Responses

悠太, 金. (2016) · Terrestrial Environment Research Center (University of Tsukuba)

Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis and Cancer EtiologyPreprint

Peddu, C., Zhang, S., Zhao, H. L., Lee, E. Y. C., Lee, M., & Zhang, Z. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3185110

Four germline POLH variants, including two found in skin tumors, impair DNA polymerase η function and cellular tolerance to UV radiation and cisplatin

Hong, J., Yeom, M., Hwang, H.-Y., Mun, E., Woo, J.-H., Kim, Y., Shin, J., Lee, Y., Kim, D., Guengerich, F. P., et al. (2025) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2025.111551

Pathogenicity, functional significance and clinical phenotype of mismatch repair gene MSH2 variants found in cancer patients

Ollila, S. (2008) · Työväentutkimus Vuosikirja

Characterisation of UVA-induced DNA damage responses in human skin cells

Conmy, S. A. (2013) · Arrow@dit (Dublin Institute of Technology) · doi:10.13025/16394

La voie de dégradation CRL4Cdt2 régule le recrutement des ADN polymérases translésionnelles eta et kappa en foyers nucléaires après endommagements aux UV-C en ciblant pour dégradation les protéines qui contiennent des PIP box spécialisées

Tsanov, N. (2012) · theses.fr (ABES) · doi:10.70675/2122f712z2f95z45caz8f82za68872f01e3c

Caractérisation fonctionnelle de la tolérance aux endommagements de l’ADN des embryons précoces

Furno, E. L. (2019) · theses.fr (ABES) · doi:10.70675/cf32bcd5z3031z4693z8b1bz62fe76673ccc

UV-B Radiation Induces Epithelial Tumors in Mice Lacking DNA Polymerase η and Mesenchymal Tumors in Mice Deficient for DNA Polymerase ι

Ohkumo, T., Kondo, Y., Yokoi, M., Tsukamoto, T., Yamada, A., Sugimoto, T., Kanao, R., Higashi, Y., Kondoh, H., Tatematsu, M., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01076-06 · Cited by 111 · see citing works

UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι.

Kanao, R., Yokoi, M., Ohkumo, T., Sakurai, Y., Dotsu, K., Kura, S., Nakatsu, Y., Tsuzuki, T., Masutani, C., & Hanaoka, F. (2015) · DNA Repair · doi:10.1016/j.dnarep.2015.02.006 · Cited by 21 · see citing works

Mutations in DNA polymerase η are not detected in squamous cell carcinoma of the skin

Glick, E., White, L. M., Elliott, N., Berg, D., Kiviat, N. B., & Loeb, L. A. (2006) · International Journal of Cancer · doi:10.1002/ijc.22099 · Cited by 9 · see citing works

Role of DNA Polymerase η in the UV Mutation Spectrum in Human Cells

Stary, A., Kannouche, P. L., Lehmann, A. R., & Sarasin, A. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211838200 · Cited by 127 · see citing works

Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase η, DNA Polymerase ι Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations

Wang, Y., Woodgate, R., McManus, T. P., Mead, S., McCormick, J. J., & Maher, V. M. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3073 · Cited by 120 · see citing works