Cited by 263Dialysis and Renal Disease ManagementMindfulness and Compassion InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Psychosocial Intervention Improves Depression, Quality of Life, and Fluid Adherence in Hemodialysis

Open access
Cukor, Daniel, Ver Halen, Nisha, Asher, Deborah Rosenthal, Coplan, Jeremy D., Weedon, Jeremy, Wyka, Katarzyna E., Saggi, Subodh J., Kimmel, Paul L.·2014·Journal of the American Society of Nephrology

Abstract

Patients with ESRD have high rates of depression, which is associated with diminished quality of life and survival. We determined whether individual cognitive behavioral therapy (CBT) reduces depression in hemodialysis patients with elevated depressive affect in a randomized crossover trial. Of 65 participants enrolled from two dialysis centers in New York, 59 completed the study and were assigned to the treatment-first group (n=33) or the wait-list control group (n=26). In the intervention phase, CBT was administered chairside during dialysis treatments for 3 months; participants were assessed 3 and 6 months after randomization. Compared with the wait-list group, the treatment-first group achieved significantly larger reductions in Beck Depression Inventory II (self-reported, P=0.03) and Hamilton Depression Rating Scale (clinician-reported, P<0.001) scores after intervention. Mean scores for the treatment-first group did not change significantly at the 3-month follow-up. Among participants with depression diagnosed at baseline, 89% in the treatment-first group were not depressed at the end of treatment compared with 38% in the wait-list group (Fisher's exact test, P=0.01). Furthermore, the treatment-first group experienced greater improvements in quality of life, assessed with the Kidney Disease Quality of Life Short Form (P=0.04), and interdialytic weight gain (P=0.002) than the wait-list group, although no effect on compliance was evident at follow-up. In summary, CBT led to significant improvements in depression, quality of life, and prescription compliance in this trial, and studies should be undertaken to assess the long-term effects of CBT on morbidity and mortality in patients with ESRD.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1681/asn.2012111134

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. [39]39. First MB, Spitzer RL, Gibbon M, Williams J: Structured Clinical Interview for DSM-IV Diagnoses, (SCID-I) , Washington, D.C., American Psychiatric Press, Inc., 1997

Cited by

Sorted by citations

Authors
Cukor, D., Ver Halen, N., Asher, D. R., Coplan, J. D., Weedon, J., Wyka, K. E., Saggi, S. J., & Kimmel, P. L.
Affiliations
  • SUNY Downstate Health Sciences University (US)
  • Weill Cornell Medical Center (US)
  • George Washington University (US)
Corresponding author
  • Cukor, Daniel
  • Coplan, Jeremy D.
Venue
Journal of the American Society of Nephrology
Published
2014-01
Volume
25
Issue
1
Pages
196-206
ISSN
1046-6673 (ISSN-L)
OpenAlex
W2169214416
Cited by
263
References
50
Citations by year
2026: 10 · 2025: 28 · 2024: 16 · 2023: 20 · 2022: 15 · 2021: 24 · 2020: 30 · 2019: 27 · 2018: 26 · 2017: 15 · 2016: 24 · 2015: 11 · 2014: 16
FWCI
12.89
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Society of Nephrology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health
  • National Institute of Diabetes and Digestive and Kidney Diseases (K23DK076980)
Topics
  • Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
depression, end-stage renal disease, hemodialysis, cognitive behavioral therapy, psychosocial interventions, quality of life, interdialytic weight gain, medication adherence, dialysis
MeSH terms
Depression, Female, Renal Dialysis, Humans, Kidney Failure, Chronic, Male, Patient Compliance, Quality of Life, Water-Electrolyte Balance, Cognitive Behavioral Therapy, Cross-Over Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review