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Cited by 39

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age.

Mehdipour, Melod, Etienne, Jessy, Chen, Chia-Chien, Gathwala, Ranveer, Rehman, Maryam, Kato, Cameron, Liu, Chao, Liu, Yutong, Zuo, Yi, Conboy, Michael J., Conboy, Irina M.·2019·Aging
DOI 10.18632/aging.102148PMC PMC6710051
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Crossref · 10.18632/aging.102148

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  • Adiposity and fibrosis were higher in OO livers compared to YY.

    “Adiposity and fibrosis were higher in the OO livers as compared to YY, as published [1, 9, 14].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [14]

    The Results section ('Alk5i+OT reduces liver adiposity, and liver fibrosis'; page unavailable) states that both measures increase with age, and Figure 4 describes fibrotic clusters as common in old but not young livers. However, this paper labels its comparison groups old control and young control, not OO and YY; it does not establish the claim for those specifically named groups. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

  • YY muscles regenerated much better than OO.

    “YY muscles regenerated much better than OO, as expected [1, 9, 14, 15].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [14]

    The Results section (‘In vivo delivery of Alk5i and OT’; page unavailable) says newly formed muscle fibers developed efficiently in young but not old injured muscles. That supports the age-related comparison, but the paper describes young and old control mice (Yc and Oc), not YY and OO groups. (LLM, conf=0.83)

    Experimental — accuracy not yet measured

  • Attenuation of TGF-beta signaling in old animals has effects similar to those of NBE.

    “and the fact that attenuation of TGF-beta signaling in old animals has effects that are similar to those of NBE [7, 14, 15, 28, 44].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [14]

    The Results section (page not provided) says Alk5 inhibition plus oxytocin improved liver health in old mice to a similar extent as blood exchange. It also reports benefits of Alk5 inhibition alone for muscle regeneration and hippocampal neurogenesis, but does not establish that attenuation alone has effects similar to blood exchange. The paper does not use the term NBE. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • Liver adiposity and fibrosis are known to increase with age and to be influenced by blood heterochronicity.

    “Liver adiposity and fibrosis are known to increase with age and to be influenced by blood heterochronicity [1, 9, 14, 35–38].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [14]

  • Neurogenesis in the subgranular zone of the hippocampus continues throughout adult life, dramatically declines with advanced age and is influenced by blood heterochronicity.

    “Neurogenesis in the subgranular zone (SGZ) of the hippocampus continues throughout adult life, dramatically declines with advanced age and is influenced by blood heterochronicity [7, 9, 14, 26].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [14]

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Citations

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Research works printed but not linked: 41

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Metadata

Authors
Mehdipour, M., Etienne, J., Chen, C.-C., Gathwala, R., Rehman, M., Kato, C., Liu, C., Liu, Y., Zuo, Y., Conboy, M. J., & Conboy, I. M.
Affiliations
  • Department of Bioengineering and QB3 Institute, University of California, Berkeley, Berkeley, CA 94720, USA
  • Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
Venue
Aging
Publisher
Impact Journals, LLC
Published
2019-08-15
Volume
11
Issue
15
Pages
5628-5645
ISSN
1945-4589
DOI
10.18632/aging.102148
PMC
PMC6710051
Cited by
39
References
20
Language
en

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