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Cited by 13Diabetes Management and ResearchDiabetes Management and EducationDiabetes and associated disorders

Continuous Glucose Monitoring and Type 1 Diabetes Mellitus Control in Child, Adolescent and Young Adult Population – Arguments for Its Use and Effects

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Rubelj, Karla·2021·Acta Clinica Croatica
DOI 10.20471/acc.2021.60.04.07PMC PMC9196217
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Abstract

Sensors for continuous glucose monitoring (CGM) in intercellular fluid are used as a contemporary method to achieve better control in type 1 diabetes mellitus (DM), which is best shown through lower glycated hemoglobin (HbA1c) levels.The aim of this study was to assess how many of our patients used CGM (parents were solely financing all the cost of the device) and what was the effect of CGM on the control of DM. Data were retrospectively collected from medical records of patients actively treated at the Division of Endocrinology, Diabetology, Pulmonology and Allergology, Department of Pediatrics, Sestre milosrdnice University Hospital Center. The t-test was used for independent samples to compare the mean levels of HbA1c before and after the inclusion of CGM. CGM was used by 81 (32.1%) of our patients with type 1 DM, of which 43 met the inclusion criteria. The mean HbA1c level 6 months before the introduction of CGM was 8.2%±1.9 and after 12 months of CGM use it was 7.4%±1.2, which was a statistically significant improvement (p=0.026). Furthermore, our results demonstrated that the greatest improvement in HbA1c level was recorded in the groups of young adults (18-25 years) and youngest children (<12 years). We confirmed the efficacy of CGM in achieving better control of type 1 DM by significantly improving HbA1c levels in a population of highly motivated patients.

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  • CGM has been extensively utilized in patients with Type 1 Diabetes, and emerging evidence supports its potential benefits in managing T2D.

    “While CGM has been extensively utilized in patients with Type 1 Diabetes [7–9], emerging evidence supports its potential benefits in managing T2D.”

    From Sequential use of continuous glucose monitoring, with or without exercise trackers, significantly improves glycemic control in patients with type 2 diabetes (2025) · cites this paper as [8]

    The Introduction describes CGM as a validated method for type 1 diabetes, supporting its established use. But it also says clinical use is “still quite modest” and reports use by 20%–30% of children with type 1 diabetes, so “extensively utilized” overstates this source. The T2D clause follows the citation and is not attributed to it. (LLM, conf=0.84)

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Research works printed but not linked: 27

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Sorted by citations

Authors
Rubelj, K.
Affiliations
University Hospital Centre Zagreb (HR)
Corresponding author
Rubelj, Karla
Venue
Acta Clinica Croatica
Publisher
Sestre Milosrdnice University Hospital Center (KBC Sestre milosrdnice)
Published
2021
Volume
60
Issue
4
Pages
609-616
ISSN
0353-9466 (ISSN-L)
DOI
10.20471/acc.2021.60.04.07
PMC
PMC9196217
OpenAlex
W4285547261
Cited by
13
References
8
Citations by year
2026: 3 · 2025: 6 · 2024: 3 · 2023: 1
FWCI
0.73
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Acta Clinica Croatica (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Keywords
continuous glucose monitoring, type 1 diabetes, glycemic control, HbA1c, children, adolescents, young adults, pediatric diabetes
MeSH terms
Adolescent, Blood Glucose, Child, Diabetes Mellitus, Type 1, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Insulin, Retrospective Studies, Blood Glucose Self-Monitoring, Young Adult

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