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SHARPIN Promotes Melanoma Progression via Rap1 Signaling Pathway

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Withholding of M-CSF Supplement Reprograms Macrophages to M2-Like via Endogenous CSF-1 Activation

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MicroRNA-30b-5p functions as a metastasis suppressor in colorectal cancer by targeting Rap1b

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Profiling and Bioinformatics Analyses of Differential Circular RNA Expression in Prostate Cancer Cells

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Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase

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Functional diversity in the RAS subfamily of small GTPases

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miR-200b/c-RAP1B axis represses tumorigenesis and malignant progression of papillary thyroid carcinoma through inhibiting the NF-κB/Twist1 pathway

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Identifying the key regulators that promote cell-cycle activity in the hearts of early neonatal pigs after myocardial injury

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Multifunctional 4D printed shape memory composite scaffolds with photothermal and magnetothermal effects for multimodal tumor therapy and bone repair

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Proteomic Approach for Searching for Universal, Tissue-Specific, and Line-Specific Markers of Extracellular Vesicles in Lung and Colorectal Adenocarcinoma Cell Lines

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Molecular crosstalk between COVID-19 and Alzheimer’s disease using microarray and RNA-seq datasets: A system biology approach

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Psychiatric adverse events following COVID-19 vaccination: a population-based cohort study in Seoul, South Korea

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Expression Profiles of Exosomal miRNAs Isolated from Plasma of Patients with Desmoplastic Small Round Cell Tumor

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A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility

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Cancer Genomic Alterations Can Be Potential Biomarkers Predicting Microvascular Invasion and Early Recurrence of Hepatocellular Carcinoma

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Endocrine Disrupting Chemicals Influence Hub Genes Associated with Aggressive Prostate Cancer

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Molecular evidence of field cancerization initiated by diabetes in colon cancer patients

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Multiple Processes May Involve in the IgG4-RD Pathogenesis: An Integrative Study via Proteomic and Transcriptomic Analysis

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Cyclic Adenosine Monophosphate in Cardiac and Sympathoadrenal GLP-1 Receptor Signaling: Focus on Anti-Inflammatory Effects

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The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer

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Immune-Related Nine-MicroRNA Signature for Predicting the Prognosis of Gastric Cancer

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Identification of phenotype-specific networks from paired gene expression–cell shape imaging dataPreprint

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RAP1GAP Functions as a Tumor Suppressor Gene and Is Regulated by DNA Methylation in Differentiated Thyroid Cancer

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Platelet Membrane: An Outstanding Factor in Cancer Metastasis

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Biomarker Value of miR-221 and miR-222 as Potential Substrates in the Differential Diagnosis of Papillary Thyroid Cancer Based on Data Synthesis and Bioinformatics Approach

Cai, S., Ma, J., Wang, Y., Cai, Y., Xie, L., Chen, X., Yang, Y., & Peng, Q. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.794490 · Cited by 17

Eukaryotic initiation factor 3, subunit C silencing inhibits cell proliferation and promotes apoptosis in human ovarian cancer cells

Wen, F., Wu, Z.-Y., Nie, L., Zhang, Q.-Z., Qin, Y., Zhou, Z., Wu, J.-J., Zhao, X., Tan, J. R., Sawmiller, D. R., et al. (2019) · Bioscience Reports · doi:10.1042/bsr20191124 · Cited by 16

Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines

Zsigrai, S., Kalmár, A., Barták, B. K., Nagy, Z. B., Szigeti, K. A., Valcz, G., Kothalawala, W. J., Dankó, T., Sebestyén, A. R., Barna, G., et al. (2022) · Cancers · doi:10.3390/cancers14071820 · Cited by 16

Tocotrienol isoforms: The molecular mechanisms underlying their effects in cancer therapy and their implementation in clinical trials

Younes, M., Loubnane, G., Sleiman, C., & Rizk, S. E. (2024) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2024.01.002 · Cited by 16

Decreased expression of miR-410-3p correlates with poor prognosis and tumorigenesis in human glioma

Wang, C., Huang, S., Rao, S., Hu, J., Zhang, Y., Luo, J., & Wang, H. (2019) · Cancer Management and Research · doi:10.2147/cmar.s202247 · Cited by 15

Evaluation of Diagnostic Potential of Epigenetically Deregulated MiRNAs in Epithelial Ovarian Cancer

Kumar, V., Gupta, S., Chaurasia, A., & Sachan, M. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.681872 · Cited by 15

Self‐Assembled DNA Nanocages Promote Cell Migration and Differentiation of Human Umbilical Vein Endothelial Cells**

Rajwar, A., Vaswani, P., Singh, R. S., & Bhatia, D. D. (2023) · ChemBioChem · doi:10.1002/cbic.202200634 · Cited by 15

Low GPR81 in ER+ breast cancer cells drives tamoxifen resistance through inducing PPARα-mediated fatty acid oxidation

Yu, J., Du, Y., Liu, C., Xie, Y., Yuan, M., Shan, M., Li, N., Liu, C., Wang, Y., & Qin, J. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122763 · Cited by 15

Genome-wide methylation analysis identifies novel prognostic methylation markers in colon adenocarcinoma

Xue, W., Wu, X., Wang, F., Han, P., & Cui, B. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.09.043 · Cited by 15

Identification of Key Genes and Prognostic Analysis between Chromophobe Renal Cell Carcinoma and Renal Oncocytoma by Bioinformatic Analysis

Wu, H., Fan, L., Liu, H., Guan, B., Hu, B., Liu, F., Hocher, B., & Yin, L. (2020) · BioMed Research International · doi:10.1155/2020/4030915 · Cited by 14

CD34+ HSPCs-derived exosomes contain dynamic cargo and promote their migration through functional binding with the homing receptor E-selectin

Isaioglou, I., Aldehaiman, M. M., Li, Y., Lahcen, A. A., Rauf, S., Al-Amoodi, A. S., Habiba, U., Alghamdi, A., Nozue, S., Habuchi, S., et al. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1149912 · Cited by 13

Comparative profiling of whole-cell and exosome samples reveals protein signatures that stratify breast cancer subtypes

Andreu, Z., Hidalgo, M. R., Masiá, E., Romera-Giner, S., Malmierca-Merlo, P., López‐Guerrero, J. A., Garcia‐García, F., & Vicent, M. J. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05403-z · Cited by 13

An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma

Gao, Y., Shen, L., Dong, T., Yang, X. L., Cui, H., Guo, Y., Ma, Y., Kong, P., Cheng, X., Zhang, L., et al. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03489-2 · Cited by 13

A protein microarray‐based serum proteomic investigation reveals distinct autoantibody signature in colorectal cancer

Barpanda, A., Tuckley, C., Ray, A., Banerjee, A., Duttagupta, S. P., Kantharia, C. V., & Srivastava, S. (2022) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.202200062 · Cited by 12

Uncovering missed indels by leveraging unmapped reads

Hasan, M. S., Wu, X., & Zhang, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-47405-z · Cited by 13

Systematic understanding of anti-tumor mechanisms of Tamarixetin through network and experimental analyses

Shaji, S. K., Drishya, G., Sunilkumar, D., Suravajhala, P., Kumar, G. B., & Nair, B. G. (2022) · Scientific Reports · doi:10.1038/s41598-022-07087-6 · Cited by 12

Centrosome amplification promotes cell invasion via cell–cell contact disruption and Rap-1 activation

Prakash, A., Paunikar, S., Webber, M., McDermott, E. A., Vellanki, S. H., Thompson, K., Dockery, P., Jahns, H., Brown, J. A. L., Hopkins, A. M., et al. (2023) · Journal of Cell Science · doi:10.1242/jcs.261150 · Cited by 14

Characterization of MicroRNA expression profiles in the ovarian tissue of goats during the sexual maturity period

Wang, Y., Wang, J., Li, Q., Xuan, R., Guo, Y., He, P., & Chao, T. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-023-01318-8 · Cited by 13

Plexin-B1 Mutation Drives Metastasis in Prostate Cancer Mouse Models

Shorning, B. Y., Trent, N., Griffiths, D. F. R., Worzfeld, T., Offermanns, S., Smalley, M. J., & Williamson, M. P. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0480 · Cited by 12

Identification of potential key genes in esophageal adenocarcinoma using bioinformatics

Dong, Z., Wang, J., Zhang, H., Zhan, T., Chen, Y., & Xu, S. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7973 · Cited by 12

Loss of TTC17 promotes breast cancer metastasis through RAP1/CDC42 signaling and sensitizes it to rapamycin and paclitaxel

Zhang, J., Guo, F., Li, C., Wang, Y., Wang, J., Sun, F., Zhou, Y., Ma, F., Zhang, B., & Qian, H. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01004-8 · Cited by 11

Pravastatin‐induced changes in expression of long non‐coding and coding RNAs in endothelial cells

Singh, S., Nguyen, H. C., Ehsan, M., Michels, D., Singh, P., Qadura, M., & Singh, K. K. (2020) · Physiological Reports · doi:10.14814/phy2.14661 · Cited by 10

Integrative Predictive Modeling of Metastasis in Melanoma Cancer Based on MicroRNA, mRNA, and DNA Methylation Data

Kutlay, A., & Son, Y. A. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.637355 · Cited by 11

Identification of potentially functional circular RNAs hsa_circ_0070934 and hsa_circ_0004315 as prognostic factors of hepatocellular carcinoma by integrated bioinformatics analysis

Morovat, P., Morovat, S., Ashrafi, A. M., & Teimourian, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-08867-w · Cited by 11

Driver gene detection through Bayesian network integration of mutation and expression profiles

Chen, Z., Lü, Y., Cao, B., Zhang, W., Edwards, A., & Zhang, K. (2022) · Bioinformatics · doi:10.1093/bioinformatics/btac203 · Cited by 11

The Roles of Rap1 in Cancer Metastasis and Pancreatic Islet Beta Cell Function

Bailey, C. L. (2009) · DukeSpace (Duke University) · Cited by 6

Rac1: A Regulator of Cell Migration and a Potential Target for Cancer Therapy

Ma, N., Xu, E., Luo, Q., & Song, G. (2023) · Molecules · doi:10.3390/molecules28072976 · Cited by 87

Rap1 promotes Prostate Cancer metastasis

Bailey, C. L., & Casey, P. J. (2008) · The FASEB Journal · doi:10.1096/fasebj.22.1_supplement.1029.7

Tumor Cell Migration and Invasion Are Enhanced by Depletion of Rap1 GTPase-activating Protein (Rap1GAP)

Tsygankova, O. M., Wang, H., & Meinkoth, J. L. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.464594 · Cited by 30

Reduced Rap1 Signaling Is Associated with Prostate Cancer Progression, Migration, Invasion, and Metastasis

Henderson, V., Osunkoya, A. O., Zhou, W., Williams, D. J., Anderson, N., Kitayama, H., CSETE, M. E., & Moreno, C. S. (2009) · The FASEB Journal · doi:10.1096/fasebj.23.1_supplement.438.2