Mechanism of Traditional Chinese Medicine in Treating Knee Osteoarthritis
Open accessAbstract
Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to chronic pain, edema, and limited mobility of knee joint. Traditional Chinese Medicine (TCM) is a common complementary therapy for KOA and has been found effective. The aim of this review is to consolidate the current knowledge about the mechanism of four interventions of TCM: acupuncture, moxibustion, herbs, and massage in treating KOA, and how they alleviate symptoms such as pain, swelling, and dysfunction. Furthermore, this review highlights that four therapies have different mechanisms but all of them can manage KOA through inhibiting inflammation, which indicates that alternative therapies should be considered as a viable complementary treatment for pain management in clinical practice.
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Acupuncture has been used in diabetes for a long time in Asian countries, and recent studies have suggested that acupuncture may alleviate sarcopenic obesity.
“Acupuncture has been used in diabetes for a long time in Asian countries and recent studies have also suggested that acupuncture may alleviate SO (197–199).”
From Diabetes and Sarcopenic Obesity: Pathogenesis, Diagnosis, and Treatments (2020) · cites this paper as [199]
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Self-citation
- Authors
- Wang, M., Liu, L., Zhang, C. S., Liao, Z., Jing, X., Fishers, M., Zhao, L., Xu, X., & Li, B.
- Affiliations
- Beijing University of Chinese Medicine (CN)
- Capital Medical University (CN)
- RMIT University (AU)
- Nanyang Technological University (SG)
- Beth Israel Deaconess Medical Center (US)
- Corresponding author
- Li, Bin
- Venue
- Journal of Pain Research
- Publisher
- Informa UK Limited
- Published
- 2020-06
- Volume
- Volume 13
- Pages
- 1421-1429
- ISSN
- 1178-7090 (ISSN-L)
- PMC
- PMC7304682
- OpenAlex
- W3034998433
- Cited by
- 104
- References
- 78
- Citations by year
- 2026: 10 · 2025: 21 · 2024: 21 · 2023: 22 · 2022: 21 · 2021: 7 · 2020: 2
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Pain Research (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- DR-NTU (Nanyang Technological University) (submittedVersion, cc-by-nc)
- Figshare (submittedVersion, cc-by-nc)
- Funders
- China Association for Science and Technology (2019-2021ZGZJXH-QNRC001, QNRC001)
- China Postdoctoral Science Foundation (2018M630261)
- Beijing Dongcheng District People's Government
- Topics
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Studies
- Keywords
- knee osteoarthritis, traditional Chinese medicine, acupuncture, moxibustion, herbal medicine, massage, pain management, inflammation reduction, complementary therapy, knee joint dysfunction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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