The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Ultraviolet B Regulation of Transcription Factor Families: Roles of Nuclear Factor-kappa B (NF-κB) and Activator Protein-1 (AP-1) in UVB-Induced Skin Carcinogenesis
Open accessAbstract
Prolonged and repeated exposure of the skin to ultraviolet light (UV) leads not only to aging of the skin but also increases the incidence of non-melanoma skin cancer (NMSC). Damage of cells induced by ultraviolet B (UVB) light both at the DNA level and molecular level initiates the activation of transcription factor pathways, which in turn regulate the expression of a number of genes termed the "UV response genes". Two such transcription factor families that are activated in this way are those of the nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) families. These two transcription factor families have been identified to be involved in the processes of cell proliferation, cell differentiation and cell survival and therefore play important roles in tumorigenesis. The study of these two transcription factor pathways and the cross-talk between them in response to UVB exposure may help with the development of new chemopreventive strategies for the prevention of UVB-induced skin carcinogenesis.
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Cites
Sunburn and p53 in the onset of skin cancer
Ziegler, A., Jonason, A. S., Leffellt, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jacks, T., & Brash, D. E. (1994) · Nature · doi:10.1038/372773a0 · Cited by 1,497
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
Dajee, M., Lazarov, M., Zhang, J. Y., Cai, T., Green, C. L., Russell, A. J., Marinkovich, M. P., Tao, S., Lin, Q., Kubo, Y., et al. (2003) · Nature · doi:10.1038/nature01283 · Cited by 535
You, Y.-H., Lee, D.-H., Yoon, J.-H., Nakajima, S., Yasui, A., & Pfeifer, G. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107696200 · Cited by 314
Afaq, F., Adhami, V. M., & Ahmad, N. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(02)00014-5 · Cited by 262
AP1/ jun Function Is Differentially Induced in Promotion-Sensitive and Resistant JB6 Cells
Bernstein, L. R., & Colburn, N. H. (1989) · Science · doi:10.1126/science.2541502 · Cited by 207
A role for NF-κB–dependent gene transactivation in sunburn
Abeyama, K., Eng, W., Jester, J. V., Vink, A. A., Edelbaum, D., Cockerell, C. J., Bergstresser, P. R., & Takashima, A. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9745 · Cited by 160
Role of P38 MAPK in UVB-Induced Inflammatory Responses in the Skin of SKH-1 Hairless Mice
Kim, A. L., Labasi, J. M., Zhu, Y., Tang, X., McClure, K., Gabel, C. A., Athar, M., & Bickers, D. R. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23747.x · Cited by 153
Ma, C., Wang, J., & Luo, J. (2004) · Biochemical Pharmacology · doi:10.1016/j.bcp.2004.01.023 · Cited by 43
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Monchaud, D., & Teulade-Fichou, M.-P. (2008) · Org. Biomol. Chem. · doi:10.1039/b714772b · Cited by 788
Cell Type-Specific Roles of NF-κB Linking Inflammation and Thrombosis
Mussbacher, M., Salzmann, M., Brostjan, C., Hoesel, B., Schoergenhofer, C., Datler, H., Hohensinner, P., Basílio, J., Petzelbauer, P., Assinger, A., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00085 · Cited by 596
Natural products as photoprotection
Saewan, N., & Jimtaisong, A. (2015) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.12123 · Cited by 306
Natural Antioxidants: Multiple Mechanisms to Protect Skin From Solar Radiation
Dunaway, S., Odin, R., Zhou, L., Ji, L., Zhang, Y., & Kadekaro, A. L. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00392 · Cited by 280
NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy
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Metadata
- Authors
- Cooper, S., & Bowden, G.
- Venue
- Current Cancer Drug Targets
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2007-06-01
- Volume
- 7
- Issue
- 4
- Pages
- 325-334
- ISSN
- 1568-0096 (ISSN-L)
- OpenAlex
- W2076754005
- Cited by
- 204
- References
- 8
- FWCI
- 10.77
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Ultraviolet B Regulation of Transcription Factor Families: Roles of Nuclear Factor-kappa B (NF-κB) and Activator Protein-1 (AP-1) in UVB-Induced Skin Carcinogenesis. https://app.cochat.ai/papers/10.2174/156800907780809714
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- Cooper, S., & Bowden, G. (2007). Ultraviolet B Regulation of Transcription Factor Families: Roles of Nuclear Factor-kappa B (NF-κB) and Activator Protein-1 (AP-1) in UVB-Induced Skin Carcinogenesis. Current Cancer Drug Targets. https://doi.org/10.2174/156800907780809714
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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