The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
The Role of Phenolic Compounds in the Fight against Cancer – A Review
Open accessAbstract
Cancer is a worldwide scourge; it's the leading cause of death in developed countries and is increasing in developing countries. Mankind has been trying with effort to find better and cheaper treatments with fewer side effects, to reduce the incidence of the disease and its consequent mortality. For many years, phenolic compounds have been intensely studied for their antitumor, proapoptotic and antiangiogenic effects. In recent years, the usage of these compounds has increased considerably. This manuscript intends to structurally characterize the different phenolic compounds (flavonoids, hydroxycinnamates, hydroxybenzoates, coumarins, xanthones, chalcones, stilbenes, lignins and lignans) and their metabolic pathways as well as review the most important results regarding these compounds and their derivatives in cancer treatment and prevention both in tumor cell lines in vitro, in murine models in vivo and finally some results regarding human trials.
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1 retracted
Mohammad, R. M., Banerjee, S., Li, Y., Aboukameel, A., Küçük, Ö., & Sarkar, F. H. (2006) · Cancer · doi:10.1002/cncr.21731 · Cited by 77
RetractedJemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20107 · Cited by 54,679
Cancer immunoediting: from immunosurveillance to tumor escape
Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J., & Schreiber, R. D. (2002) · Nature Immunology · doi:10.1038/ni1102-991 · Cited by 5,393
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935 · cited 1×
“The first record of its chemopreventive activity dates back to 1997 [123].”
BackgroundTumors: Wounds That Do Not Heal
Flier, J. S., Underhill, L. H., & Dvorak, H. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612253152606 · Cited by 4,391 · cited 1×
“Understanding the similarities between wounds and the development of cancer as well as the wrong healing patters may help understand the uncontrolled growth of tumors [62-64].”
BackgroundCancer Epidemiology and Prevention
(2006) · doi:10.1093/acprof:oso/9780195149616.001.0001 · Cited by 3,369
The biochemistry and medical significance of the flavonoids
Havsteen, B. H. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00298-x · Cited by 2,672
Cancer is a preventable disease that requires major lifestyle changes
Anand, P., Kunnumakara, A. B., Sundaram, C., Harikumar, K. B., Tharakan, S. T., Lai, O. S., Sung, B., & Aggarwal, B. B. (2008) · Pharmaceutical Research · doi:10.1007/s11095-008-9661-9 · Cited by 2,632
Chemical studies of anthocyanins: A review
Castañeda-Ovando, A., Pacheco-Hernández, M. D. L., Páez-Hernández, M. E., Rodríguez, J. A., & Galán-Vidal, C. A. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2008.09.001 · Cited by 2,552
Tannins and Human Health: A Review
Chung, K.-T., Wong, T. Y., Wei, C.-I., Huang, Y.-W., & Lin, Y. (1998) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408699891274273 · Cited by 1,996
Cited by
Adding Molecules to Food, Pros and Cons: A Review on Synthetic and Natural Food Additives
Carocho, M., Barreiro, M. F., Morales, P., & Ferreira, I. C. F. R. (2014) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12065 · Cited by 767
Self-citationNatural food additives: Quo vadis?
Carocho, M., Morales, P., & Ferreira, I. C. F. R. (2015) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2015.06.007 · Cited by 585
Self-citationUltrasound Assisted Extraction for the Recovery of Phenolic Compounds from Vegetable Sources
Medina-Torres, N., Ayora-Talavera, T., Espinosa-Andrews, H., Sánchez-Contreras, A., & Pacheco, N. (2017) · Agronomy · doi:10.3390/agronomy7030047 · Cited by 502
Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort
Bondonno, N. P., Dalgaard, F., Kyrø, C., Murray, K., Bondonno, C. P., Lewis, J. R., Croft, K. D., Gislason, G., Scalbert, A., Cassidy, A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11622-x · Cited by 322
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
Liu, Z., Li, J., Li, S., Li, G., Sharpless, K. B., & Wu, P. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b12788 · Cited by 319
Metadata
- Authors
- Carocho, M., & Ferreira, I.
- Venue
- Anti-Cancer Agents in Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2013-09-01
- Volume
- 13
- Issue
- 8
- Pages
- 1236-1258
- ISSN
- 1568-0118 (ISSN-L)
- 1871-5206
- OpenAlex
- W1986072191
- Cited by
- 267
- References
- 153
- FWCI
- 9.86
- Type
- journal article
- Language
- en
- Open access
- green
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