Pathogen recognition by innate immunity and its signaling

Pathogen Recognition and Innate Immunity

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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A Toll-like receptor recognizes bacterial DNA

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., Taira, K., Akira, S., & Fujita, T. (2004) · Nature Immunology · doi:10.1038/ni1087 · Cited by 4,022

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., & Bauer, S. (2004) · Science · doi:10.1126/science.1093620 · Cited by 3,947

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K. J., et al. (2006) · Nature · doi:10.1038/nature04734 · Cited by 3,888

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

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The airway epithelium: soldier in the fight against respiratory viruses

Vareille, M., Kieninger, E., Edwards, M. R., & Regamey, N. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-10 · Cited by 655

International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis

Wise, S. K., Lin, S. Y., Toskala, E., Orlandi, R. R., Akdis, C. A., Alt, J. A., Azar, A., Baroody, F. M., Bachert, C., Canonica, G. W., et al. (2018) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22073 · Cited by 557

COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation

Zabetakis, I., Lordan, R., Norton, C., & Τσούπρας, Α. (2020) · Nutrients · doi:10.3390/nu12051466 · Cited by 553

International consensus statement on allergy and rhinology: Allergic rhinitis – 2023

Wise, S. K., Damask, C. C., Roland, L. T., Ebert, C. S., Levy, J. M., Lin, S. Y., Luong, A., Rodriguez, K., Sedaghat, A. R., Toskala, E. M., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23090 · Cited by 584

Cell-to-cell communication: microRNAs as hormones.

Bayraktar, R., Van Roosbroeck, K., & Calin, G. A. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12144 · Cited by 361

TLR signaling in mast cells: common and unique features

Sandig, H., & Bulfone‐Paus, S. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00185 · Cited by 268

Inflammation and Cell Death of the Innate and Adaptive Immune System during Sepsis

Nedeva, C. (2021) · Biomolecules · doi:10.3390/biom11071011 · Cited by 279

Avian toll-like receptors

Brownlie, R. M., & Allan, B. J. (2010) · Cell and Tissue Research · doi:10.1007/s00441-010-1026-0 · Cited by 266

Evolutionary Origins of Toll-like Receptor Signaling

Brennan, J. J., & Gilmore, T. D. (2018) · Molecular Biology and Evolution · doi:10.1093/molbev/msy050 · Cited by 233

Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota

Sharma, R. R., Young, C., & Neu, J. (2010) · BioMed Research International · doi:10.1155/2010/305879 · Cited by 220

Response of gut health and microbiota to sulfide exposure in Pacific white shrimp Litopenaeus vannamei

Suo, Y., Li, E., Li, T., Jia, Y., Qin, J. G., Gu, Z., & Chen, L. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.02.008 · Cited by 163

Application of nanotechnologies for improved immune response against infectious diseases in the developing world

Look, M., Bandyopadhyay, A., Blum, J. S., & Fahmy, T. M. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.011 · Cited by 152

Identification of a C-type lectin with antiviral and antibacterial activity from pacific white shrimp Litopenaeus vannamei

Li, M., Li, C., Ma, C., Li, H., Zuo, H., Weng, S., Chen, X., Zeng, D., He, J., & Xu, X. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.04.014 · Cited by 139

Inductive expression of toll-like receptor 5 (TLR5) and associated downstream signaling molecules following ligand exposure and bacterial infection in the Indian major carp, mrigal (Cirrhinus mrigala)

Basu, M., Swain, B., Maiti, N. K., Routray, P., & Samanta, M. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.10.031 · Cited by 121

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

Zhou, Y., Xie, Y., Tang, L., Pu, D., Zhu, Y., Liu, J., & Ma, X. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00733-x · Cited by 116

Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism

Pal, S., Bhattacharjee, A., Ali, A., Mandal, N. C., Mandal, S. C., & Pal, M. (2014) · Journal of Inflammation · doi:10.1186/1476-9255-11-23 · Cited by 119

Virus-induced secondary bacterial infection: a concise review

Hendaus, M. A., Jomha, F. A., & Alhammadi, A. H. (2015) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s87789 · Cited by 113

Dengue Virus Control of Type I IFN Responses: A History of Manipulation and Control

Castillo, J. A., & Inchima, S. U. (2015) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2014.0129 · Cited by 99

Molecular characterization of toll-like receptor 2 (TLR2), analysis of its inductive expression and associated down-stream signaling molecules following ligands exposure and bacterial infection in the Indian major carp, rohu (Labeo rohita)

Samanta, M., Swain, B., Basu, M., Panda, P., Mohapatra, G. B., Sahoo, B. R., & Maiti, N. K. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.11.029 · Cited by 99

MDA5 plays a critical role in interferon response during hepatitis C virus infection

Cao, X., Ding, Q., Lu, J. L., Tao, W., Huang, B. S., Zhao, Y., Niu, J., Liu, Y., & Zhong, J. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.11.007 · Cited by 97

Development of innate immunity in chicken embryos and newly hatched chicks: a disease control perspective

Alkie, T. N., Yitbarek, A., Hodgins, D. C., Kulkarni, R. R., Taha-Abdelaziz, K., & Sharif, S. (2019) · Avian Pathology · doi:10.1080/03079457.2019.1607966 · Cited by 107

Natural products and the search for novel vaccine adjuvants

Rey-Ladino, J., Ross, A. G., Cripps, A. W., McManus, D. P., & Quinn, R. J. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.07.041 · Cited by 94

Establishing targeted carp TLR22 gene disruption via homologous recombination using CRISPR/Cas9

Chakrapani, V., Patra, S. K., Panda, R. P., Rasal, K. D., Jayasankar, P., & Barman, H. K. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.04.009 · Cited by 90

Targeting TLR2 for Vaccine Development

Basto, A. P., & Leitão, A. (2014) · Journal of Immunology Research · doi:10.1155/2014/619410 · Cited by 88

Clinically feasible approaches to potentiating cancer cell-based immunotherapies

Seledtsov, V. I., Гончаров, А. Г., & Seledtsova, G. V. (2015) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1009814 · Cited by 87

Molecular characterization of a fish‐specific toll‐like receptor 22 (TLR22) gene from common carp (Cyprinus carpio L.): Evolutionary relationship and induced expression upon immune stimulants

Li, H., Yang, G.-W., Ma, F., Li, T., Yang, H.-T., Rombout, J., & An, L. (2017) · Fish and Shellfish Immunology · doi:10.1016/j.fsi.2017.02.009 · Cited by 81

CsCTL1, a teleost C-type lectin that promotes antibacterial and antiviral immune defense in a manner that depends on the conserved EPN motif

Zhou, Z., & Sun, L. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.01.007 · Cited by 89

A high-concentrate diet induced colonic epithelial barrier disruption is associated with the activating of cell apoptosis in lactating goats

Tao, S., Duanmu, Y., Dong, H., Tian, J., Ni, Y., & Zhao, R. (2014) · BMC Veterinary Research · doi:10.1186/s12917-014-0235-2 · Cited by 80

Immune mechanisms in cerebral ischemic tolerance

García‐Bonilla, L., Benakis, C., Moore, J. M. R., Iadecola, C., & Anrather, J. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00044 · Cited by 86

Expression analysis of nine Toll-like receptors in yellow catfish ( Pelteobagrus fulvidraco ) responding to Aeromonas hydrophila challenge

Zhang, X., Zhang, G., Shi, Z.-C., Yuan, Y.-J., Zheng, H., Lin, L., Wei, K.-J., & Ji, W. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.02.021 · Cited by 76

Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans

Nogales, A., Martínez‐Sobrido, L., Chiem, K., Topham, D. J., & DeDiego, M. L. (2018) · Journal of Virology · doi:10.1128/jvi.01206-18 · Cited by 76

Gene expression profiling in live attenuated Edwardsiella tarda vaccine immunized and challenged zebrafish: Insights into the basic mechanisms of protection seen in immunized fish

Yang, D., Liu, Q., Ni, C., Li, S., Wu, H., Wang, Q., Xiao, J., & Zhang, Y. (2013) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2013.01.014 · Cited by 76

Ginkgolides and bilobalide protect BV2 microglia cells against OGD/reoxygenation injury by inhibiting TLR2/4 signaling pathways

Zhou, J., Gu, S.-S., Mei, W. H., Zhou, J., Wang, Z. Z., & Xiao, W. (2016) · Cell Stress and Chaperones · doi:10.1007/s12192-016-0728-y · Cited by 75

Non-mammalian Toll-like receptor 18 (Tlr18) recognizes bacterial pathogens in common carp (Cyprinus carpio L.): Indications for a role of participation in the NF-κB signaling pathway

Shan, S., Liu, D., Liu, R., Zhu, Y., Li, T., Zhang, F., An, L., Yang, G., & Li, H. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.09.081 · Cited by 74

Immunobiotic Lactobacillus rhamnosus strains differentially modulate antiviral immune response in porcine intestinal epithelial and antigen presenting cells

Villena, J., Chiba, E., Vizoso-Pinto, M. G., Tomosada, Y., Takahashi, T., Ishizuka, T., Aso, H., Salva, S., Alvarez, S., & Kitazawa, H. (2014) · BMC Microbiology · doi:10.1186/1471-2180-14-126 · Cited by 75

Damaged spermatogenic cells induce inflammatory gene expression in mouse Sertoli cells through the activation of Toll-like receptors 2 and 4

Zhang, X., Wang, T., Deng, T., Xiong, W., Lui, P., Li, N., Chen, Y., & Han, D. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.10.016 · Cited by 72

Interferon-Dependent and Respiratory Virus-Specific Interference in Dual Infections of Airway Epithelia

Essaidi-Laziosi, M., Geiser, J., Huang, S., Constant, S., Kaiser, L., & Tapparel, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-66748-6 · Cited by 71

Induction of toll-like receptor (TLR) 2, and MyD88-dependent TLR- signaling in response to ligand stimulation and bacterial infections in the Indian major carp, mrigal (Cirrhinus mrigala)

Basu, M., Swain, B., Sahoo, B. R., Maiti, N. K., & Samanta, M. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-1415-9 · Cited by 70

Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I

Wen, W., Yin, M., Zhang, H., Liu, T., Chen, H., Qian, P., Hu, J., & Li, X. (2019) · Virology · doi:10.1016/j.virol.2019.06.017 · Cited by 66

Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications?

Darwesh, A. M., Bassiouni, W., Sosnowski, D. K., & Seubert, J. M. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107703 · Cited by 66

The c-Fos and c-Jun from Litopenaeus vannamei play opposite roles in Vibrio parahaemolyticus and white spot syndrome virus infection

Li, C., Li, H., Wang, S., Song, X., Zhang, Z., Qian, Z., Zuo, H., Xu, X., Weng, S., & He, J. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.04.009 · Cited by 63

Activation of PPARγ inhibits pro-inflammatory cytokines production by upregulation of miR-124 in vitro and in vivo

Wang, D., Shi, L., Xin, W., Xu, J., Xu, J., Li, Q., Xu, Z. Z., Wang, J., Wang, G., Yao, W., et al. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.03.106 · Cited by 63

Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells

Bulgari, O., Dong, X., Roca, A. L., Caroli, A. M., & Loor, J. J. (2017) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-017-0162-8 · Cited by 61

Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity

Hawash, M. B. F., Sanz-Remón, J., Grenier, J.-C., Kohn, J., Yotova, V., Johnson, Z., Lanford, R. E., Brinkworth, J. F., & Barreiro, L. B. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2015855118 · Cited by 56

Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation

Khan, P. M., Correa, R. G., Divlianska, D. B., Peddibhotla, S., Sessions, E. H., Magnuson, G., Brown, B. T., Suyama, E., Yuan, H., Mangravita-Novo, A., et al. (2011) · ACS Medicinal Chemistry Letters · doi:10.1021/ml200158b · Cited by 59

Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity

Murphy, M. B., & Medvedev, A. E. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.2ru1215-575r · Cited by 57

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages

Minematsu, H., Shin, M., Celil, A. B., Kim, K.-O., Nizami, S. A., Chung, G.-J., & Lee, F. Y. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.06.013 · Cited by 57

RNase L Cleavage Products Promote Switch from Autophagy to Apoptosis by Caspase-Mediated Cleavage of Beclin-1

Siddiqui, M. A., Mukherjee, S., Manivannan, P., & Malathi, K. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160817611 · Cited by 55

First evidence of comparative responses of Toll-like receptor 22 (TLR22) to relatively resistant and susceptible Indian farmed carps to Argulus siamensis infection

Panda, R. P., Chakrapani, V., Patra, S. K., Saha, J. N., Jayasankar, P., Kar, B., Sahoo, P. K., & Barman, H. K. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.06.016 · Cited by 55

Identification and expression analysis of TLR2 in mucosal tissues of turbot (Scophthalmus maximus L.) following bacterial challenge

Liu, F., Su, B., Gao, C., Zhou, S., Song, L., Tan, F., Dong, X., Ren, Y., & Li, C. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.06.047 · Cited by 55

Modulation of TLR2, TLR4, TLR5, NOD1 and NOD2 receptor gene expressions and their downstream signaling molecules following thermal stress in the Indian major carp catla (Catla catla)

Basu, M., Paichha, M., Swain, B., Lenka, S. S., Singh, S., Chakrabarti, R., & Samanta, M. (2015) · 3 Biotech · doi:10.1007/s13205-015-0306-5 · Cited by 53

High Concentrate Diet Induced Mucosal Injuries by Enhancing Epithelial Apoptosis and Inflammatory Response in the Hindgut of Goats

Tao, S., Duanmu, Y., Dong, H., Ni, Y., Chen, J., Shen, X., & Zhao, R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111596 · Cited by 53

Toll-Like Receptor 22 in Labeo rohita: Molecular Cloning, Characterization, 3D Modeling, and Expression Analysis Following Ligands Stimulation and Bacterial Infection

Samanta, M., Swain, B., Basu, M., Mahapatra, G., Sahoo, B. R., Paichha, M., Lenka, S. S., & Jayasankar, P. (2014) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-014-1058-0 · Cited by 53

SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association

Hu, Y., Wang, Y., Wang, F., Dong, Y., Jiang, W., Wang, Y., Zhong, X., & Ma, L. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0411-1 · Cited by 54

Microecology, intestinal epithelial barrier and necrotizing enterocolitis

Sharma, R. R., & Tepas, J. J. (2009) · Pediatric Surgery International · doi:10.1007/s00383-009-2536-2 · Cited by 52

Methionine and arginine supplementation alter inflammatory and oxidative stress responses during lipopolysaccharide challenge in bovine mammary epithelial cells in vitro

Dai, H., Coleman, D. N., Hu, L., Martínez-Cortés, I., Wang, M., Parys, C., Shen, X., & Loor, J. J. (2019) · Journal of Dairy Science · doi:10.3168/jds.2019-16631 · Cited by 56

The cereus matter of Bacillus endophthalmitis

Mursalin, M. H., Livingston, E. T., & Callegan, M. C. (2020) · Experimental Eye Research · doi:10.1016/j.exer.2020.107959 · Cited by 51

Characterization and expression analysis of Toll-like receptor 2 gene in large yellow croaker, Larimichthys crocea

Fan, Z.-J., Jia, Q., & Yao, C.-L. (2015) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2015.01.037 · Cited by 49

A high-concentrate diet induces colonic inflammation and barrier damage in Hu sheep

Chen, M., Xie, W., Zhou, S., Ma, N., Wang, Y., Huang, J., Shen, X., & Chang, G. (2023) · Journal of Dairy Science · doi:10.3168/jds.2023-23359 · Cited by 57

Structure‐Based Design of Novel Human Toll‐like Receptor 8 Agonists

Kokatla, H. P., Sil, D., Tanji, H., Ohto, U., Malladi, S. S., Fox, L. M., Shimizu, T., & David, S. A. (2014) · ChemMedChem · doi:10.1002/cmdc.201300573 · Cited by 48

Upper Airway Stem Cells: Understanding the Nose and Role for Future Cell Therapy

Wang, D. Y., Li, Y., Yan, Y., Li, C., & Shi, L. (2014) · Current Allergy and Asthma Reports · doi:10.1007/s11882-014-0490-0 · Cited by 47

Comparative Analysis of Species-Specific Ligand Recognition in Toll-Like Receptor 8 Signaling: A Hypothesis

Govindaraj, R. G., Manavalan, B., Basith, S., & Choi, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025118 · Cited by 47

TIP60 represses activation of endogenous retroviral elements

Rajagopalan, D., Tirado-Magallanes, R., Bhatia, S. S., Teo, W. S., Sian, S., Hora, S., Lee, K. K., Zhang, Y., Jadhav, S. P., Wu, Y., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky659 · Cited by 47

Design and Development of Stable, Water-Soluble, Human Toll-like Receptor 2 Specific Monoacyl Lipopeptides as Candidate Vaccine Adjuvants

Salunke, D. B., Connelly, S. W., Shukla, N. M., Hermanson, A. R., Fox, L. M., & David, S. A. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm400620g · Cited by 45

Genetic polymorphisms in Toll-like receptor 3 gene are associated with the risk of hepatitis B virus-related liver diseases in a Chinese population

Huang, X., Li, H., Wang, J., Huang, C., Yu, L., Qin, X. Y., & Li, S. (2015) · Gene · doi:10.1016/j.gene.2015.05.054 · Cited by 44

Detection of Lipid and Amphiphilic Biomarkers for Disease Diagnostics

Kubicek-Sutherland, J. Z., Vu, D. M., Mendez, H. M., Jakhar, S., & Mukundan, H. (2017) · Biosensors · doi:10.3390/bios7030025 · Cited by 44

Global Proteomics Revealed Klebsiella pneumoniae Induced Autophagy and Oxidative Stress in Caenorhabditis elegans by Inhibiting PI3K/AKT/mTOR Pathway during Infection

Kamaladevi, A., & Balamurugan, K. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00393 · Cited by 43

Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model

Achek, A., Shah, M., Seo, J. Y., Kwon, H., Gui, X., Shin, H., Cho, E.-Y., Lee, B. S., Kim, D.-J., Lee, S. H., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00061 · Cited by 42

NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

Yu, L. P., Phillips, R. L., Zhang, D., Teghanemt, A., Weiss, J. P., & Gioannini, T. L. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.343467 · Cited by 41

Toll-like receptor 2 of tongue sole Cynoglossus semilaevis : Signaling pathway and involvement in bacterial infection

Li, X., & Sun, L. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.03.001 · Cited by 41

Discovery of inulin acetate as a novel immune-active polymer and vaccine adjuvant: synthesis, material characterization, and biological evaluation as a toll-like receptor-4 agonist

Kumar, S., Kesharwani, S. S., Kuppast, B., Rajput, M., Bakkari, M. A., & Tummala, H. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb02181f · Cited by 41

Pentraxin 3 deletion aggravates allergic inflammation through a TH17-dominant phenotype and enhanced CD4 T-cell survival

Balhara, J., Shan, L., Zhang, J., Muhuri, A., Halayko, A. J., Almiski, M. S., Doeing, D. C., McConville, J. F., Matzuk, M. M., & GOUNNI, A. S. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.04.063 · Cited by 40

Pathogen-Derived Oligosaccharides Improve Innate Immune Response to Intracellular Parasite Infection

Osanya, A., Song, E.-H., Metz, K. A., Shimak, R. M. K., Boggiatto, P. M., Huffman, E. L., Johnson, C. S., Hostetter, J. M., Pohl, N. L. B., & Petersen, C. A. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.05.053 · Cited by 39

A balance between tissue-destructive and tissue-protective immunities: A role of toll-like receptors in regulation of adaptive immunity

Seledtsov, V. I., & Seledtsova, G. V. (2011) · Immunobiology · doi:10.1016/j.imbio.2011.10.011 · Cited by 38

Structure−Activity Relationships in Nucleotide Oligomerization Domain 1 (Nod1) Agonistic γ-Glutamyldiaminopimelic Acid Derivatives

Agnihotri, G., Ukani, R., Malladi, S. S., Warshakoon, H. J., Balakrishna, R., Wang, X., & David, S. A. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm101535e · Cited by 39

NLRC5: A paradigm for NLRs in immunological and inflammatory reaction

Wu, Y., Shi, T., & Li, J. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.03.005 · Cited by 39

Establishment of a Caenorhabditis elegans infection model for Vibrio alginolyticus

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Protein phosphatase PP1 negatively regulates the Toll-like receptor- and RIG-I-like receptor-triggered production of type I interferon by inhibiting IRF3 phosphorylation at serines 396 and 385 in macrophage

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