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Cited by 527

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Intravoxel Incoherent Motion in Body Diffusion-Weighted MRI: Reality and Challenges

Koh, Dow-Mu, Collins, David J., Orton, Matthew R.·2011·American Journal of Roentgenology

Abstract

OBJECTIVE: Diffusion-weighted MRI is increasingly applied in the body. It has been recognized for some time, on the basis of scientific experiments and studies in the brain, that the calculation of apparent diffusion coefficient by simple monoexponential relationship between MRI signal and b value does not fully account for tissue behavior. However, appreciation of this fact in body diffusion MRI is relatively new, because technologic advancements have only recently enabled high-quality body diffusion-weighted images to be acquired using multiple b values. There is now increasing interest in the radiologic community to apply more sophisticated analytic approaches, such as those based on the principles of intravoxel incoherent motion, which allows quantitative parameters that reflect tissue microcapillary perfusion and tissue diffusivity to be derived. CONCLUSION: In this review, we discuss the principles of intravoxel incoherent motion as applied to body diffusion-weighted MRI. The evidence for the technique in measuring tissue perfusion is presented and the emerging clinical utility surveyed. The requisites and challenges of quantitative evaluation beyond simple monoexponential relationships are highlighted.

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Metadata

Authors
Koh, D.-M., Collins, D. J., & Orton, M. R.
Venue
American Journal of Roentgenology
Published
2011-06
Volume
196
Issue
6
Pages
1351-1361
ISSN
  • 0002-9580 (ISSN-L)
  • 0361-803X
  • 1546-3141
OpenAlex
W2167594413
Cited by
527
References
55
FWCI
24.36
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Intravoxel Incoherent Motion in Body Diffusion-Weighted MRI: Reality and Challenges. https://app.cochat.ai/papers/10.2214/ajr.10.5515
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Koh, D.-M., Collins, D. J., & Orton, M. R. (2011). Intravoxel Incoherent Motion in Body Diffusion-Weighted MRI: Reality and Challenges. American Journal of Roentgenology. https://doi.org/10.2214/ajr.10.5515

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