Quantum Dots as A Theranostic Approach in Alzheimer’s Disease: A Systematic Review
Abstract
Aim: Quantum dots (QDs) are nanoparticles that have an emerging application as theranostic agents in several neurodegenerative diseases. The advantage of QDs as nanomedicine is due to their unique optical properties that provide high sensitivity, stability and selectivity at a nanoscale range. Objective: To offer renewed insight into current QD research and elucidate its promising application in Alzheimer's disease (AD) diagnosis and therapy. Methods: A comprehensive literature search was conducted in PubMed and Google Scholar databases that included the following search terms: ‘quantum dots’, ‘blood–brain barrier’, ‘cytotoxicity’, ‘toxicity’ and ‘Alzheimer's disease’; PRISMA guidelines were adhered to. Results: Thirty-four publications were selected to evaluate the ability of QDs to cross the blood–brain barrier, potential toxicity and current AD diagnostic and therapeutic applications. Conclusion: QD's unique optical properties and versatility to conjugate to various biomolecules, while maintaining a nanoscale size, render them a promising theranostic tool in AD.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
For QD, diagnostic concentrations range from 50 nM to 15 mg/kg, while therapeutic ones vary from 5 μM to 200 μg/kg.
“For QD, diagnostic concentrations range from 50 nM to 15 mg/kg, while therapeutic ones vary from 5 μM to 200 μg/kg [91].”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [91]
An analysis of the systematic reviews by Villalva and co-authors on QD and Aminyavari and co-authors on SPIONs showed that neither provides an example of a nanoparticle for which both diagnostic and therapeutic doses were quantitatively determined within a single study.
“An analysis of the systematic reviews by Villalva and co-authors [91] on QD and Aminyavari and co-authors [92] on SPIONs showed that neither provides an example of a nanoparticle for which both diagnostic and therapeutic doses were quantitatively determined within a single study.”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [91]
In the tables summarizing diagnostic and therapeutic approaches, different sets of particles appear.
“In the tables summarizing diagnostic and therapeutic approaches, different sets of particles appear [91,92].”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [91]
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease
Jack, C. R., Bennett, D. A., Blennow, K., Carrillo, M. C., Dunn, B., Haeberlein, S. B., Holtzman, D. M., Jagust, W., Jessen, F., Karlawish, J., et al. (2018) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2018.02.018 · Cited by 10,537 · see citing works
Semiconductor Nanocrystals as Fluorescent Biological Labels
Bruchez, M. P., Moronne, M. M., Gin, P., Weiss, S., & Alivisatos, A. P. (1998) · Science · doi:10.1126/science.281.5385.2013 · Cited by 8,614 · see citing works
Understanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083 · see citing works
Astrocyte-endothelial interactions at the blood-brain barrier
Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595 · see citing works
Structure and function of the blood–brain barrier
Abbott, N. J., Patabendige, A. A. K., Dolman, D. E. M., Yusof, S. R., & Begley, D. J. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.07.030 · Cited by 5,185 · see citing works
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
Haass, C., & Selkoe, D. J. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2101 · Cited by 4,744 · see citing works
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
Klunk, W. E., Engler, H., Nordberg, A., Wang, Y., Blomqvist, G., Holt, D. P., Bergström, M., Savitcheva, I., Huang, G., Estrada, S., et al. (2004) · Annals of Neurology · doi:10.1002/ana.20009 · Cited by 4,496 · see citing works
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476 · see citing works
Oxidative mechanisms in the toxicity of metal ions
Stohs, S. J., & Bagchi, D. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00159-h · Cited by 4,219 · see citing works
Quantum dots versus organic dyes as fluorescent labels
Resch‐Genger, U., Grabolle, M., Cavaliere-Jaricot, S., Nitschke, R., & Nann, T. (2008) · Nature Methods · doi:10.1038/nmeth.1248 · Cited by 3,836 · see citing works
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
Bateman, R. J., Xiong, C., Benzinger, T. L. S., Fagan, A. M., Goate, A., Fox, N. C., Marcus, D. S., Cairns, N. J., Xie, X., Blazey, T. M., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1202753 · Cited by 3,814 · see citing works
Probing the Cytotoxicity of Semiconductor Quantum Dots
Derfus, A. M., Chan, W. C. W., & Bhatia, S. N. (2003) · Nano Letters · doi:10.1021/nl0347334 · Cited by 3,394 · see citing works
Cellular uptake of nanoparticles: Journey inside the cell
Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., Brown, D., Alkilany, A. M., Farokhzad, O. C., & Mahmoudi, M. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00636a · Cited by 2,859 · see citing works
Hydrothermal Route for Cutting Graphene Sheets into Blue‐Luminescent Graphene Quantum Dots
Pan, D., Zhang, J., Li, Z., & Wu, M. (2009) · Advanced Materials · doi:10.1002/adma.200902825 · Cited by 2,857 · see citing works
Molecular mechanism of Thioflavin-T binding to amyloid fibrils
Biancalana, M., & Koide, S. (2010) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2010.04.001 · Cited by 2,203 · see citing works
Glowing Graphene Quantum Dots and Carbon Dots: Properties, Syntheses, and Biological Applications
Zheng, X. T., Ananthanarayanan, A., Luo, K. Q., & Chen, P. (2015) · Small · doi:10.1002/smll.201402648 · Cited by 2,190 · see citing works
Karran, E., Mercken, M., & Strooper, B. D. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3505 · Cited by 2,188 · see citing works
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Shaw, L. M., Vanderstichele, H., Knapik‐Czajka, M., Clark, C. M., Aisen, P. S., Petersen, R. C., Blennow, K., Soares, H., Simon, A., Lewczuk, P., et al. (2009) · Annals of Neurology · doi:10.1002/ana.21610 · Cited by 2,065 · see citing works
Nelson, P. T., Alafuzoff, I., Bigio, E. H., Bouras, C., Braak, H., Cairns, N. J., Castellani, R. J., Crain, B. J., Davies, P., Tredici, K. D., et al. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31825018f7 · Cited by 2,050 · see citing works
Alzheimer’s disease drug-development pipeline: Few candidates, frequent failures
Cummings, J. L., Morstorf, T., & Zhong, K. (2014) · Alzheimer's Research & Therapy · doi:10.1186/alzrt269 · Cited by 1,744 · see citing works
Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
Doody, R. S., Thomas, R. G., Farlow, M., Iwatsubo, T., Vellas, B., Joffe, S., Kieburtz, K., Raman, R., Sun, X., Aisen, P. S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1312889 · Cited by 1,668 · see citing works
Cytotoxicity of Colloidal CdSe and CdSe/ZnS Nanoparticles
Kirchner, C., Liedl, T., Kudera, S., Pellegrino, T., Muñoz Javier, A., Gaub, H. E., Stölzle, S., Fertig, N., & Parak, W. J. (2005) · Nano Letters · doi:10.1021/nl047996m · Cited by 1,619 · see citing works
A review on Alzheimer's disease pathophysiology and its management: an update
Kumar, A., Singh, A., & Ekavali (2015) · Pharmacological Reports · doi:10.1016/j.pharep.2014.09.004 · Cited by 1,578 · see citing works
Quantum Dots and Their Multimodal Applications: A Review
Bera, D., Qian, L., Tseng, T.-K., & Holloway, P. H. (2010) · Materials · doi:10.3390/ma3042260 · Cited by 1,365 · see citing works
Abuchowski, A., McCoy, J. R., Palczuk, N. C., Es, T. V., & Davis, F. F. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40292-4 · Cited by 1,276 · see citing works
Fagan, A. M., Mintun, M. A., Mach, R. H., Lee, S., Dence, C. S., Shah, A. R., LaRossa, G. N., Spinner, M. L., Klunk, W. E., Mathis, C. A., et al. (2006) · Annals of Neurology · doi:10.1002/ana.20730 · Cited by 1,246 · see citing works
In vivo molecular and cellular imaging with quantum dots
Gao, X., Yang, L. P. H., Petros, J. A., Marshall, F. F., Simons, J. W., & Nie, S. (2004) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2004.11.003 · Cited by 1,213 · see citing works
Bioconjugated quantum dots for in vivo molecular and cellular imaging☆
SMITH, A., Duan, H., Mohs, A. M., & Nie, S. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.015 · Cited by 1,196 · see citing works
Bacon, M., Bradley, S. J., & Nann, T. (2013) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.201300252 · Cited by 1,014 · see citing works
The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception
Weiner, M. W., Veitch, D. P., Aisen, P. S. S., Beckett, L. A., Cairns, N. J., Green, R. C., Harvey, D. J., Jack, C. R., Jagust, W. J., Liu, E., et al. (2013) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2013.05.1769 · Cited by 1,011 · see citing works
Graphene: Exploring carbon flatland
Geim, A., & MacDonald, A. H. (2007) · Physics Today · doi:10.1063/1.2774096 · Cited by 863 · see citing works
Highly Luminescent CdSe/ZnSe Core/Shell Nanocrystals of Low Size Dispersion
Reiß, P., Bleuse, J., & Proń, A. (2002) · Nano Letters · doi:10.1021/nl025596y · Cited by 852 · see citing works
Neuropathology of Alzheimer's Disease
Perl, D. P. (2010) · Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine · doi:10.1002/msj.20157 · Cited by 825 · see citing works
Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study
Maiti, D., Tong, X., Mou, X., & Yang, K. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01401 · Cited by 735 · see citing works
A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
Nakagawa, S., Deli, M. A., Kawaguchi, H., Shimizudani, T., Shimono, T., Kittel, Á., Tanaka, K., & Niwa, M. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2008.12.002 · Cited by 728 · see citing works
Rowe, C. C., Ackerman, U., Browne, W. F., Mulligan, R. S., Pike, K. E., O'Keefe, G. J., Tochon‐Danguy, H., Chan, G., Berlangieri, S. U., Jones, G. R., et al. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70001-2 · Cited by 671 · see citing works
Lipid Rafts and Caveolae as Portals for Endocytosis: New Insights and Common Mechanisms
Parton, R. G., & Richards, A. A. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.00128.x · Cited by 603 · see citing works
Drug treatments in Alzheimer’s disease
Briggs, R., Kennelly, S. P., & O’Neill, D. (2016) · Clinical Medicine · doi:10.7861/clinmedicine.16-3-247 · Cited by 571 · see citing works
Synthesis, properties and biomedical applications of carbon-based quantum dots: An updated review
Namdari, P., Negahdari, B., & Eatemadi, A. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.12.108 · Cited by 571 · see citing works
In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots
Nurunnabi, M., Khatun, Z., Huh, K. M., Park, S. Y., Lee, D. Y., Cho, K.-J., & Lee, Y.-K. (2013) · ACS Nano · doi:10.1021/nn402043c · Cited by 546 · see citing works
The in vitro and in vivo toxicity of graphene quantum dots
Chong, Y., Ma, Y., Shen, H., Tu, X., Zhou, X., Xu, J., Dai, J., Fan, S., & Zhang, Z. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.021 · Cited by 531 · see citing works
Cadmium, Gene Regulation, and Cellular Signalling in Mammalian Cells
Beyersmann, D., & Hechtenberg, S. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1997.8125 · Cited by 523 · see citing works
Mechanisms of Quantum Dot Nanoparticle Cellular Uptake
Zhang, L. W., & Monteiro-Riviere, N. A. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp087 · Cited by 499 · see citing works
Amyloid biomarkers in Alzheimer's disease
Blennow, K., Mattsson, N., Schöll, M., Hansson, O., & Zetterberg, H. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.03.002 · Cited by 470 · see citing works
Delivery of bioactive molecules into the cell: the Trojan horse approach
Dietz, G. P. H., & Bähr, M. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.03.005 · Cited by 469 · see citing works
Setyawati, M. I., Tay, C. Y., Chia, S. L., Goh, S. L. G., Fang, W., Neo, M. J., Chong, H. C., Tan, S., Loo, S. C. J., Ng, K. W., et al. (2013) · Nature Communications · doi:10.1038/ncomms2655 · Cited by 458 · see citing works
Graphene quantum dots prevent α-synucleinopathy in Parkinson’s disease
Kim, D., Yoo, J. M., Hwang, H., Lee, J., Lee, S. H., Yun, S. P., Park, M. J., Lee, M., Choi, S., Kwon, S. H., et al. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0179-y · Cited by 455 · see citing works
Glutathione, a first line of defense against cadmium toxicity
Singhal, R. K., Anderson, M. E., & Meister, A. (1987) · The FASEB Journal · doi:10.1096/fasebj.1.3.2887478 · Cited by 396 · see citing works
Origin of Excitation Dependent Fluorescence in Carbon Nanodots
Sharma, A., Gadly, T., Gupta, A., Ballal, A. D., Ghosh, S. K., & Kumbhakar, M. (2016) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.6b01791 · Cited by 373 · see citing works
Quantum dots for fluorescent biosensing and bio-imaging applications
Li, J., & Zhu, J. (2013) · The Analyst · doi:10.1039/c3an36705c · Cited by 369 · see citing works
Synthesis and Cell‐Imaging Applications of Glutathione‐Capped CdTe Quantum Dots
Zheng, Y., Gao, S., & Ying, J. Y. (2007) · Advanced Materials · doi:10.1002/adma.200600342 · Cited by 343 · see citing works
Santra, S., Yang, H., Holloway, P. H., Stanley, J. T., & Mericle, R. A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0464140 · Cited by 327 · see citing works
Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues
Brambilla, D., Droumaguet, B. L., Nicolas, J., Hashemi, S. H., Wu, L., Moghimi, S. M., Couvreur, P., & Andrieux, K. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.03.008 · Cited by 293 · see citing works
Alzheimer disease, the two-hit hypothesis: An update
Zhu, X., Lee, H., Perry, G. L., & Smith, M. A. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.10.014 · Cited by 292 · see citing works
Setyawati, M. I., Tay, C. Y., Bay, B., & Leong, D. T. (2017) · ACS Nano · doi:10.1021/acsnano.7b01744 · Cited by 283 · see citing works
A Three-Stage Kinetic Model of Amyloid Fibrillation
Lee, C.-C., Nayak, A., Sethuraman, A., Belfort, G., & McRae, G. J. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.098608 · Cited by 278 · see citing works
Temperature-Dependent Photoluminescence of CdSe-Core CdS/CdZnS/ZnS-Multishell Quantum Dots
Jing, P., Zheng, J., Ikezawa, M., Liu, X., Lv, S., Kong, X., Zhao, J., & Masumoto, Y. (2009) · The Journal of Physical Chemistry C · doi:10.1021/jp902080p · Cited by 270 · see citing works
McAlpine, F. E., Lee, J., Harms, A. S., Ruhn, K. A., Blurton-Jones, M. M., Hong, J. J., Das, P., Golde, T. E., LaFerla, F. M., Oddo, S., et al. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.01.006 · Cited by 269 · see citing works
Fluorescent graphene quantum dots for biosensing and bioimaging
Fan, Z., Li, S., Yuan, F., & Fan, L. (2015) · RSC Advances · doi:10.1039/c4ra17131d · Cited by 250 · see citing works
Ren, C., Li, D., Zhou, Q., & Hu, X. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119752 · Cited by 228 · see citing works
Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots
Wu, C., Wang, C., Han, T., Zhou, X., Guo, S., & Zhang, J. (2013) · Advanced Healthcare Materials · doi:10.1002/adhm.201300066 · Cited by 216 · see citing works
Rapid and effective labeling of brain tissue using TAT-conjugated CdS∶Mn/ZnS quantum dots
Santra, S., Yang, H., Stanley, J. T., Holloway, P. H., Moudgil, B. M., Walter, G. A., & Mericle, R. A. (2005) · Chemical Communications · doi:10.1039/b503234b · Cited by 215 · see citing works
Fullerene inhibits β-amyloid peptide aggregation
Kim, J. E., & Lee, M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00393-0 · Cited by 212 · see citing works
Receptor-mediated endocytosis of transferrin at the blood-brain barrier
ROBERTS, R. L., Fine, R. E., & Sandra, A. (1993) · Journal of Cell Science · doi:10.1242/jcs.104.2.521 · Cited by 205 · see citing works
Early detection of Alzheimer's disease using PiB and FDG PET
Cohen, A. D., & Klunk, W. E. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.05.001 · Cited by 202 · see citing works
Recent advances in the field of transition metal dichalcogenides for biomedical applications
Agarwal, V., & Chatterjee, K. (2018) · Nanoscale · doi:10.1039/c8nr04284e · Cited by 198 · see citing works
Self-citationMalhotra, M., Tomaro-Duchesneau, C., & Prakash, S. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.10.013 · Cited by 192 · see citing works
Li, H., Luo, Y., Derreumaux, P., & Wei, G. (2011) · Biophysical Journal · doi:10.1016/j.bpj.2011.09.046 · Cited by 190 · see citing works
A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease
Nordberg, A., Carter, S. F., Rinne, J., Drzezga, A., Brooks, D. J., Vandenberghe, R., Perani, D., Forsberg, A., Långström, B., Scheinin, N., et al. (2013) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-012-2237-2 · Cited by 186 · see citing works
Hanada, S., Fujioka, K., Inoue, Y., Kanaya, F., Manome, Y., & Yamamoto, K. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15021812 · Cited by 186 · see citing works
The toxicity of graphene quantum dots
Wang, S., Cole, I. S., & Li, Q. (2016) · RSC Advances · doi:10.1039/c6ra16516h · Cited by 182 · see citing works
Synthesis of Luminescent Graphene Quantum Dots with High Quantum Yield and Their Toxicity Study
Jiang, D. Y., Chen, Y., Li, N., Li, W., Wang, Z., Zhu, J., Zhang, H., Liu, B., & Xu, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144906 · Cited by 180 · see citing works
Graphene quantum dots conjugated neuroprotective peptide improve learning and memory capability
Xiao, S., Zhou, D., Luan, P., Gu, B., Feng, L., Fan, S., Liao, W., Fang, W., Yang, L., Tao, E., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.08.021 · Cited by 169 · see citing works
Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology
Hoozemans, J. J. M., Veerhuis, R., Rozemüller, A. J. M., & Eikelenboom, P. (2005) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2005.11.001 · Cited by 168 · see citing works
Intravenous TAT-GDNF Is Protective After Focal Cerebral Ischemia in Mice
Kılıç, Ü., Kılıç, E., Dietz, G. P. H., & Bähr, M. (2003) · Stroke · doi:10.1161/01.str.0000066869.45310.50 · Cited by 165 · see citing works
Graphene quantum dots for the inhibition of β amyloid aggregation
Liu, Y., Xu, L., Dai, W., Dong, H., Wen, Y., & Zhang, X. (2015) · Nanoscale · doi:10.1039/c5nr06282a · Cited by 162 · see citing works
Photosensitized Breakage and Damage of DNA by CdSe−ZnS Quantum Dots
Anas, A., Akita, H., Harashima, H., Itoh, T., Ishikawa, M., & Biju, V. (2008) · The Journal of Physical Chemistry B · doi:10.1021/jp8018606 · Cited by 160 · see citing works
Graphene Quantum Dots for Theranostics and Bioimaging
Schroeder, K. L., Goreham, R. V., & Nann, T. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1937-x · Cited by 157 · see citing works
Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS
Silva, G. A. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-s3-s4 · Cited by 151 · see citing works
Graphene Oxide as a Multifunctional Platform for Intracellular Delivery, Imaging, and Cancer Sensing
Campbell, E., Hasan, M. T., Pho, C., Callaghan, K., Akkaraju, G. R., & Naumov, A. V. (2019) · Scientific Reports · doi:10.1038/s41598-018-36617-4 · Cited by 151 · see citing works
Nanoparticle Density: A Critical Biophysical Regulator of Endothelial Permeability
Tay, C. Y., Setyawati, M. I., & Leong, D. T. (2017) · ACS Nano · doi:10.1021/acsnano.6b07806 · Cited by 150 · see citing works
Synthesis and Characterization of Aqueous Carboxyl-Capped CdS Quantum Dots for Bioapplications
Li, H., Shih, W. Y., & Shih, W. (2007) · Industrial & Engineering Chemistry Research · doi:10.1021/ie060963s · Cited by 145 · see citing works
Inhibition of beta 1–40 amyloid fibrillation with N-acetyl-l-cysteine capped quantum dots
Xiao, L., Zhao, D., Chan, W. H., Choi, M. M. F., & Li, H. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.09.014 · Cited by 143 · see citing works
CSF biomarker levels in early and late onset Alzheimer's disease
Bouwman, F. H., Schoonenboom, N. S. M., Verwey, N. A., van Elk, E. J., Kok, A., Blankenstein, M. A., Scheltens, P., & van der Flier, W. M. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.02.007 · Cited by 142 · see citing works
Lu, Y.-H., Xu, S.-C., Chen, H.-Y., He, M.-D., Deng, Y.-C., Cao, Z.-W., Pi, H.-F., Chen, C.-H., Li, M., Ma, Q., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.03.003 · Cited by 139 · see citing works
Unique properties of graphene quantum dots and their applications in photonic/electronic devices
Choi, S. (2017) · Journal of Physics D Applied Physics · doi:10.1088/1361-6463/aa5244 · Cited by 133 · see citing works
The transport pathways of polymer nanoparticles in MDCK epithelial cells
He, B., Jia, Z., Du, W., Yu, C., Fan, Y., Dai, W., Yuan, L., Zhang, H., Wang, X., Wang, J., et al. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.01.100 · Cited by 114 · see citing works
Quantum Dots Bearing Lectin-Functionalized Nanoparticles as a Platform for In Vivo Brain Imaging
Gao, X., Chen, J., Chen, J.-Y., Wu, B., Chen, H., & Jiang, X. (2008) · Bioconjugate Chemistry · doi:10.1021/bc8002698 · Cited by 113 · see citing works
How functional groups influence the ROS generation and cytotoxicity of graphene quantum dots
Zhou, Y., Sun, H., Wang, F., Ren, J., & Qu, X. (2017) · Chemical Communications · doi:10.1039/c7cc04831a · Cited by 109 · see citing works
Zhang, T., Hu, Y., Tang, M. X., Kong, L., Ying, J., Wu, T., Xue, Y., & Pu, Y. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161023279 · Cited by 107 · see citing works
Ultrasmall BiOI Quantum Dots with Efficient Renal Clearance for Enhanced Radiotherapy of Cancer
Wang, X., Guo, Z. J., Zhang, C., Zhu, S., Li, L., Gu, Z., & Zhao, Y. (2020) · Advanced Science · doi:10.1002/advs.201902561 · Cited by 107 · see citing works
Gong, P., Wang, J., Hou, K., Yang, Z., Wang, Z., Liu, Z., Han, X., & Yang, S. (2016) · Carbon · doi:10.1016/j.carbon.2016.10.091 · Cited by 79 · see citing works
Wang, X., Lei, R., Huang, H.-D., Wang, N., Yuan, L., Xiao, R., Bai, L.-D., Li, X., Li, L., & Yang, X. (2014) · Nanoscale · doi:10.1039/c4nr04136d · Cited by 78 · see citing works
Real-Time Imaging and Quantification of Amyloid-β Peptide Aggregates by Novel Quantum-Dot Nanoprobes
Tokuraku, K., Marquardt, M., & Ikezu, T. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008492 · Cited by 75 · see citing works
Clift, M. J. D., Varet, J., Hankin, S. M., Brownlee, B., Davidson, A. M., Brandenberger, C., Rothen‐Rutishauser, B., Brown, D. M., & Stone, V. (2010) · Nanotoxicology · doi:10.3109/17435390.2010.534196 · Cited by 68 · see citing works
Vajedi, F. S., Dehghani, H., & Zarrabi, A. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111627 · Cited by 62 · see citing works
In Vivo and In Vitro Monitoring of Amyloid Aggregation via BSA@FGQDs Multimodal Probe
Yousaf, M., Ahmad, M. M., Bhatti, I. A., Nasır, A., Hasan, M., Jian, X., Kalantar‐Zadeh, K., & Mahmood, N. (2018) · ACS Sensors · doi:10.1021/acssensors.8b01216 · Cited by 62 · see citing works
Mohajeri, M., Behnam, B., Barreto, G. E., & Sahebkar, A. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.03.023 · Cited by 61 · see citing works
Kato, S., Itoh, K., Yaoi, T., Tozawa, T., Yoshikawa, Y., Yasui, H., Kanamura, N., Hoshino, A., Manabe, N., Yamamoto, K., et al. (2010) · Nanotechnology · doi:10.1088/0957-4484/21/33/335103 · Cited by 59 · see citing works
Zhu, H., Liu, A., Shan, F., Yang, W. R., Zhang, W., Li, D., & Liu, J. (2016) · Carbon · doi:10.1016/j.carbon.2016.01.016 · Cited by 59 · see citing works
Rapid determination of the toxicity of quantum dots with luminous bacteria
Wang, L., Zheng, H., Long, Y., Gao, M., Hao, J., Du, J., Mao, X.-J., & Zhou, D. (2009) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2009.12.001 · Cited by 57 · see citing works
Internalization of targeted quantum dots by brain capillary endothelial cells in vivo
Paris‐Robidas, S., Brouard, D., Émond, V., Parent, M., & Calon, F. (2015) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x15608201 · Cited by 57 · see citing works
Akin, M., Jonczyk, R., Walter, J., Springer, S., Lavrentieva, A. V., Stahl, F., Green, M., & Scheper, T. H. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00491 · Cited by 53 · see citing works
Single-layer boron-doped graphene quantum dots for contrast-enhanced in vivo T 1 -weighted MRI
Wang, H., Revia, R. A., Mu, Q., Lin, G., Yen, C., & Zhang, M. (2019) · Nanoscale Horizons · doi:10.1039/c9nh00608g · Cited by 52 · see citing works
Zaheer, S. A., Thangavel, R., Wu, Y., Khan, M. M., Kempuraj, D., & Zaheer, A. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0913-z · Cited by 50 · see citing works
Tsolekile, N., Nahle, S., Zikalala, N. E., Parani, S., Sakho, E. H. M., Joubert, O., Matoetoe, M. C., Songca, S. P., & Oluwafemi, O. S. (2020) · Scientific Reports · doi:10.1038/s41598-020-61881-8 · Cited by 47 · see citing works
Effect of Nanoparticle Surface Coating on Cell Toxicity and Mitochondria Uptake
Zheng, H., Mortensen, L., Ravichandran, S., Bentley, K. L. D. M., & DeLouise, L. A. (2017) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2017.2337 · Cited by 46 · see citing works
Feng, L., Long, H., Liu, R.-K., Sun, D., Liu, C., Long, L., Li, Y., Chen, S., & Xiao, B. (2013) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-013-9943-6 · Cited by 45 · see citing works
Conjugated Quantum Dots Inhibit the Amyloid β (1–42) Fibrillation Process
Thakur, G., Mićić, M., Yang, Y., Li, W., Movia, D., Giordani, S., Zhang, H., & Leblanc, R. M. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/502386 · Cited by 43 · see citing works
CdS/ZnS nanocomposites: from mechanochemical synthesis to cytotoxicity issues
Baláž, P., Baláž, M., Dutková, E., Zorkovská, A., Kováč, J., Hronec, P., Kováč, J., Čaplovičová, M., Mojžíš, J., Mojžišová, G., et al. (2015) · Materials Science and Engineering C · doi:10.1016/j.msec.2015.09.040 · Cited by 42 · see citing works
Toxicity Tests: In Vitro and In Vivo
Dušinská, M., Rundén‐Pran, E., Schnekenburger, J., & Kanno, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809199-9.00003-3 · Cited by 39 · see citing works
Optical barcoding of PLGA for multispectral analysis of nanoparticle fate in vivo
Medina, D. X., Householder, K. T., Ceton, R. R., Kovalik, T., Heffernan, J. M., Shankar, R. V., Bowser, R. P., Wechsler‐Reya, R. J., & Sirianni, R. W. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.02.033 · Cited by 39 · see citing works
The effect of PEG functionalization on the in vivo behavior and toxicity of CdTe quantum dots
Du, Y., Zhong, Y., Dong, J., Qian, C., Sun, S., Gao, L., & Yang, D. (2019) · RSC Advances · doi:10.1039/c9ra00022d · Cited by 38 · see citing works
Modulation of β-amyloid aggregation by graphene quantum dots
Liu, C., Huang, H., Ma, L., Fang, X., Wang, C., & Yang, Y. (2019) · Royal Society Open Science · doi:10.1098/rsos.190271 · Cited by 38 · see citing works
Quantum dot-related genotoxicity perturbation can be attenuated by PEG encapsulation
Ju, L., Zhang, G., Zhang, C., Sun, L., Jiang, Y., Yan, C., Duerksen-Hughes, P. J., Zhang, X., Zhu, X., Chen, F. F., et al. (2013) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2013.01.006 · Cited by 37 · see citing works
Zheng, W., Xu, Y., Wu, D., Yao, Y., Liang, Z., Tan, H. W., & Lau, A. T. Y. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.11.074 · Cited by 36 · see citing works
Miniemulsion polymerization of styrene using carboxylated graphene quantum dots as surfactant
Dinh, L. N. M., Ramana, L. N., Agarwal, V., & Zetterlund, P. B. (2020) · Polymer Chemistry · doi:10.1039/d0py00404a · Cited by 34 · see citing works
Self-citationChen, D., Chen, B., & Yao, F. (2018) · Nanoscale Research Letters · doi:10.1186/s11671-018-2782-0 · Cited by 32 · see citing works
Burgos‐Ramos, E., Martos‐Moreno, G. Á., López, M. G., Herranz, R., Aguado‐Llera, D., Egea, J., Frechilla, D., Cenarruzabeitia, E., Leon, R. M., Arilla, E., et al. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05980.x · Cited by 31 · see citing works
Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells
Ramana, L. N., Dinh, L. N. M., & Agarwal, V. (2021) · Nanoscale Advances · doi:10.1039/d0na00935k · Cited by 30 · see citing works
Self-citationMetal‐Free Dual Modal Contrast Agents Based on Fluorographene Quantum Dots
Radhakrishnan, S., Samanta, A., Sudeep, P. M., Maldonado, K. L., Mani, S. A., Acharya, G. S., Tiwary, C. S., Singh, A. K., & Ajayan, P. M. (2016) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.201600221 · Cited by 28 · see citing works
Yang, M., Hong, J., Zhang, Y., Gao, Z., Jiang, T., Song, J., Xu, X., & Zhu, L. (2016) · Hepatobiliary & pancreatic diseases international · doi:10.1016/s1499-3872(16)60112-1 · Cited by 17 · see citing works
Dinh, L. N. M., Ramana, L. N., Kuchel, R. P., Agarwal, V., & Zetterlund, P. B. (2020) · Polymer Chemistry · doi:10.1039/d0py00925c · Cited by 16 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases
Zhang, Y., Yang, H. N., Wei, D., Zhang, X., Wang, J., Wu, X., & Chang, J. K. (2021) · Exploration · doi:10.1002/exp.20210115 · Cited by 133 · see citing works
Applications of Various Types of Nanomaterials for the Treatment of Neurological Disorders
Waris, A., Ali, A., Khan, A. U., Asim, M., Zamel, D., Fatima, K., Raziq, A., Khan, M. A., Akbar, N., Baset, A., et al. (2022) · Nanomaterials · doi:10.3390/nano12132140 · Cited by 121 · see citing works
Chakraborty, P., Dey, A., Gopalakrishnan, A. V., Swati, K., Ojha, S. K., Prakash, A., Kumar, D., Ambasta, R. K., Jha, N. K., Jha, S. K., et al. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101838 · Cited by 58 · see citing works
Chahar, M., Khaturia, S., Singh, H. L., Solanki, V. S., Agarwal, N., Sahoo, D. K., Yadav, V. K., & Patel, A. (2023) · Frontiers in Environmental Science · doi:10.3389/fenvs.2023.1226101 · Cited by 52 · see citing works
Li, Q., Yu, X., Li, X., Bao, L., Zhang, Y., Wang, S., Jiang, M., Huang, K., & Xu, L. (2023) · Small · doi:10.1002/smll.202205634 · Cited by 45 · see citing works
Antioxidant for Neurological Diseases and Neurotrauma and Bioengineering Approaches
Rizwana, N., Agarwal, V., & Nune, M. (2021) · Antioxidants · doi:10.3390/antiox11010072 · Cited by 40 · see citing works
Self-citationRecent advances in biomedical applications of carbon and graphene quantum dots: A review
Das, A., Roy, M., & Saha, M. (2024) · Biotechnology and Bioengineering · doi:10.1002/bit.28700 · Cited by 38 · see citing works
Hu, Z., Long, W., Liu, T., Guan, Y., Lei, G., Suo, Y., Jia, M., He, J., Chen, H., She, Y., et al. (2023) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2023.122517 · Cited by 33 · see citing works
Qi, X., Ye, P., & Xie, M. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104324 · Cited by 31 · see citing works
Quantum dots are time bomb: Multiscale toxicological study
Kuznetsov, D., Krylsky, D. V., Dezhurov, S. V., Gratchev, A. N., Neschisliaev, V., Orlova, E., & Kuznetsova, A. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110396 · Cited by 23 · see citing works
Joshi, R., Missong, H., Mishra, J., Kaur, S., Saini, S., Kandimalla, R. J. L., Reddy, P. H., Babu, A. M., Bhatti, G. K., & Bhatti, J. S. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.105067 · Cited by 23 · see citing works
Phafat, B., & Bhattacharya, S. (2022) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557522666220405202222 · Cited by 20 · see citing works
Dey, A., Ghosh, S., Rajendran, R. L., Bhuniya, T., Das, P., Bhattacharjee, B., Das, S., Mahajan, A. A., Samant, A., Anand, K., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179690 · Cited by 19 · see citing works
Recent progress of small-molecule-based theranostic agents in Alzheimer's disease
Gao, F., Chen, J., Zhou, Y., Cheng, L., Hu, M., & Wang, X. (2023) · RSC Medicinal Chemistry · doi:10.1039/d3md00330b · Cited by 18 · see citing works
Khan, Z. U., Khan, L. U., Uchiyama, M. K., Prado, F. M., de Faria, R. L., Costa, I. F., Miyamoto, S., Araki, K., Gidlund, M., de Brito, H. F., et al. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.2c05482 · Cited by 13 · see citing works
Advancing Nanomaterial-Based Strategies for Alzheimer’s Disease: A Perspective
Zhou, H., Yin, X., Zhang, G., Yang, Z., & Zhou, R. (2025) · JACS Au · doi:10.1021/jacsau.5c00002 · Cited by 14 · see citing works
Sokolov, P. M., Nifontova, G., Samokhvalov, P. S., Karaulov, A. V., Sukhanova, A. V., & Nabiev, I. R. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030946 · Cited by 10 · see citing works
Joshi, N., Narayan, J., & Narayan, R. J. (2024) · Materials Advances · doi:10.1039/d3ma00636k · Cited by 9 · see citing works
Applications of bionanomaterials in neurodegenerative diseases
Biswas, A., Hivare, P., Solanki, R., Gupta, S. K., & Bhatia, D. D. (2025) · Materials Advances · doi:10.1039/d4ma01215a · Cited by 9 · see citing works
Quantum dots in neurotheranostics for the treatment of Alzheimer’s disease
Sharma, T., Bashir, B., Sharma, P., andotra, N., Singh, S. K., Singh, T. G., & Vishwas, S. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102876 · Cited by 9 · see citing works
Li, M., Zhang, Y., Sun, F. Z., Huai, M., Zhang, F., Pan, J., Qu, C.-Y., Shen, F., Li, Z.-H., & Xu, L. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s479123 · Cited by 8 · see citing works
Ramana, L. N., & Agarwal, V. (2021) · Nanotechnology · doi:10.1088/1361-6528/ac1cbd · Cited by 8 · see citing works
Self-citationNanoparticle-Based Imaging Techniques in Neurological Disorders
Thangaleela, S., Wang, C., Revathi, S., Sivamaruthi, B. S., & Chaiyasut, C. (2025) · Nanotechnology in the life sciences · doi:10.1007/978-3-031-80185-3_3 · Cited by 6 · see citing works
Lerouge, F., Ong, E., Rositi, H., Mpambani, F., Berner, L.-P., Bolbos, R. I., Olivier, C., Peyrin, F., Apputukan, V. K., Monnereau, C., et al. (2022) · Nanomedicine · doi:10.2217/nnm-2022-0252 · Cited by 5 · see citing works
Drug Delivery Based on Nanoparticulate Systems
Çetin, K., & Şarkaya, K. (2024) · Düzce Üniversitesi Bilim ve Teknoloji Dergisi · doi:10.29130/dubited.1469423 · Cited by 5 · see citing works
Yang, H., Wu, C. J., Deng, Y., Yang, W., He, M., & Zhang, L. (2023) · Materials Letters · doi:10.1016/j.matlet.2023.135609 · Cited by 5 · see citing works
Recent Advancement of Nanotheranostics in Cancer Applications
Parveen, S., Rajendran, A., Paikray, S. K., Sahoo, L., Tripathy, N. S., & Dilnawaz, F. (2024) · Current Drug Delivery · doi:10.2174/0115672018307617240514092110 · Cited by 5 · see citing works
Intranasal Drug Delivery: A Non-Invasive Method for improving Neurotherapeutic Delivery
Khope, R. G., Gotmare, S. C., Dhoble, N. N., Padole, N. N., Dhapke, P. R., & Baheti, J. (2024) · Asian Journal of Pharmaceutical Research · doi:10.52711/2231-5691.2024.00008 · Cited by 4 · see citing works
Baquero, F., del Campo, R., & Martínez, J. L. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.861603 · Cited by 4 · see citing works
Evolution of Detecting Early Onset of Alzheimer’s Disease: From Neuroimaging to Optical Immunoassays
Hsiao, W. W., Angela, S., Le, T., Ku, C., Hu, P., & Chiang, W. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221202 · Cited by 4 · see citing works
Chen, Y., Pei, J., Mou, J., Fan, J., Fan, L., Zhang, Y., Guo, X. W., Fan, Y., & Sun, H. (2025) · Smart Materials in Medicine · doi:10.1016/j.smaim.2025.06.002 · Cited by 3 · see citing works
Sinha, T., Bokhari, S. F. H., Khan, M. U., Shaheer, M., Amir, M., Zia, B. F., Bakht, D., Javed, M. A., Almadhoun, M. K. I. K., Burhanuddin, M., et al. (2024) · Cureus · doi:10.7759/cureus.58677 · Cited by 3 · see citing works
Exploring Alzheimer’s diseases with focus on diagnostic strategies targeting amyloid beta 42 (Aβ42)
Chauhan, A., Devi, R., Singh, S., Bhutani, K., Prasad, S., Singh, A., Bhaskar, N., Kumar, S., Saini, A. K., & Thakur, R. (2025) · Discover Neuroscience · doi:10.1186/s13064-025-00217-6 · Cited by 4 · see citing works
Bhukta, P., Sahu, P. K., & Acharya, B. (2026) · Next Nanotechnology · doi:10.1016/j.nxnano.2026.100495 · Cited by 2 · see citing works
Toxicological aspects of nanomaterials in biomedical research
D’Costa, A., Shaikh, S. M., Kundaikar, G., & Furtado, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95253-8.00013-9 · Cited by 2 · see citing works
Chacko, L., Nag, S., Dewanjee, S., Ghosh, S., Vallamkondu, J., Mitra, O., Dey, A., Bhuniya, T., Paluru, H. P. R., Reddy, P. H., et al. (2022) · Preprints.org · doi:10.20944/preprints202211.0032.v1 · Cited by 2 · see citing works
Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions
Zorkina, Y., Abramova, O., Zubkov, E., Gurina, O., & Ushakova, V. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083560 · Cited by 1 · see citing works
“For QD, diagnostic concentrations range from 50 nM to 15 mg/kg, while therapeutic ones vary from 5 µ M to 200 µ g/kg [91].”
Rejili, M. S., Gupta, G., Singh, S. K., & Hussain, M. S. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.109343 · Cited by 1 · see citing works
Phullay, P., Panwar, R., Bajwa, S., Wadhwa, K., Chauhan, P., Pahwa, R., Kriplani, P., Rajak, H., Awasthi, R., & Dureja, H. (2026) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-026-00616-z · Cited by 1 · see citing works
Integrating radiotheranostics’ in human oncologic and non-oncologic frontiers
Ghai, A., Dhingra, K., Hazari, P. P., & Singh, B. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22300-6.00042-5 · Cited by 1 · see citing works
Welcome to the 17th Volume of Nanomedicine
Bough, A. (2021) · Nanomedicine · doi:10.2217/nnm-2021-0385
Ponomaryova, Т. S., Novikova, A. S., Sokolov, A. A., & Goryacheva, I. Y. (2022) · Computational Biophysics and Nanobiophotonics · doi:10.1117/12.2625581
Blood brain barrier and its significance in drug delivery to brain in Alzheimer disease
Rana, D., Salave, S., Khunt, D., & Benival, D. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13205-6.00018-2 · Cited by 1 · see citing works
Sabbaghi-Nadooshan, R., Akbari-Hasanjani, R., Dehbozorgi, L., Haghparast, M., & Akbari-Hasanjani, H. R. (2024) · doi:10.1002/9781394253975.ref
Ulanova, M. (2024) · Nanomedicine · doi:10.1080/17435889.2024.2428588
Self-citationNano lipid-drug conjugates for the treatment of Alzheimer’s disease
Mandal, S., & Das, M. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33382-8.00010-8
Grzeczkowicz, A., Kwiatkowska, A., Lipko, A., Kazimierczak, B., & Granicka, L. H. (2025) · Membranes · doi:10.3390/membranes15100313
Silicon quantum dots for neurotheranostic applications in dopamine detection
Tang, S., Lv, L., Liu, N., Xu, X., Zhang, H., & Yu, S. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04459-2
Chen, S., Zhou, M., Pu, S., Chen, Y., Chen, J., Gu, J., & Tan, R. (2026) · The Innovation Drug Discovery · doi:10.59717/j.xinn-drugdisc.2026.100023
Emerging nano-drug delivery strategies for management of neuropsychiatric disorders
Jaiswal, A. K., Zai, I., Hasan, N., & Sultana, Y. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108806
Devadas, R. M., & Sowmya, T. (2026) · Journal of King Saud University - Computer and Information Sciences · doi:10.1007/s44443-026-01063-0
The emerging role of nanobiomaterials in the early detection and treatment of Alzheimer’s disease
Asuku, A. O., & Olaoluwa, P. A. (2026) · Exploration of neuroscience · doi:10.37349/en.2026.1006147
Nose-to-Brain Inorganic Nanosystems for Alzheimer’s Disease Theranostics
González-Pizarro, C., Vitta, Y., & Kogan, M. J. (2026) · Journal of Pharmaceutical and BioTech Industry · doi:10.3390/jpbi3040024
BindingDB (2024) · UC San Diego · doi:10.7270/q2hq44b5
- Authors
- Villalva, M. D., Agarwal, V., Ulanova, M., Sachdev, P. S., & Braidy, N.
- Affiliations
- UNSW Sydney (AU)
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2021-06-28
- Volume
- 16
- Issue
- 18
- Pages
- 1595-1611
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W3173763732
- Cited by
- 53
- References
- 125
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 12 · 2023: 13 · 2022: 6 · 2021: 4
- FWCI
- 0.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nanomedicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Health and Medical Research Council (GNT1139060)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Quantum Dots Synthesis And Properties
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- quantum dots, Alzheimer's disease, theranostics, blood-brain barrier, nanoparticle toxicity, cytotoxicity, optical properties, biomolecule conjugation, neurodegenerative disease diagnosis, Alzheimer's disease treatment
- MeSH terms
- Theranostic Nanomedicine, Alzheimer Disease, Humans, Quantum Dots, Nanomedicine, Nanoparticles, Precision Medicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review