Cited by 218Diabetes, Cardiovascular Risks, and LipoproteinsDiet, Metabolism, and DiseasePhysical Activity and Health

Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study

Open access
Ilanne-Parikka, Pirjo, Eriksson, Johan G., Lindström, Jaana, Peltonen, Markku, Aunola, Sirkka, Hämäläinen, Helena, Keinänen-Kiukaanniemi, Sirkka, Laakso, Mauri +5 more·2008·Diabetes Care

Abstract

OBJECTIVE—The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components. RESEARCH DESIGN AND METHODS—A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome. RESULTS—At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40–0.95]) and in the prevalence of abdominal obesity (0.48 [0.28–0.81]). CONCLUSIONS—The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.2337/dc07-1117

Cites

14 of 14 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • If LDL-C goals are not achieved on maximally tolerated statins, drug combinations may offer additional LDL-C lowering, but outcome evidence is limited.

    “If LDL-C goals are not achieved on maximally tolerated doses of statins, drug combinations may offer additional lowering of LDL-C, but the evidence from outcome studies is limited. 354”

    From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [354]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Ilanne-Parikka, P., Eriksson, J. G., Lindström, J., Peltonen, M., Aunola, S., Hämäläinen, H., Keinänen-Kiukaanniemi, S., Laakso, M., Valle, T. T., Lahtela, J., Uusitupa, M., Tuomilehto, J., & on behalf of the Finnish Diabetes Prevention Study Group
Affiliations
  • Diabetes Center, Finnish Diabetes Association, Tampere, Finland
  • University of Helsinki (FI)
  • Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
  • Finnish Institute for Health and Welfare (FI)
  • Department of Health and Functional Capacity, Laboratory for Population Research, National Public Health Institute, Turku, Finland
  • Research Department, Social Insurance Institution, Turku, Finland
  • Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
  • Oulu University Hospital (FI)
  • Tampere University Hospital (FI)
  • University of Eastern Finland (FI)
Venue
Diabetes Care
Published
2008-04-01
Volume
31
Issue
4
Pages
805-807
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W2115945685
Cited by
218
References
14
Citations by year
2026: 1 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 8 · 2021: 4 · 2020: 7 · 2019: 9 · 2018: 6 · 2017: 9 · 2016: 20 · 2015: 15 · 2014: 11 · 2013: 21 · 2012: 21
FWCI
17.60
Type
journal article
Language
en
Open access
Locations
  • Diabetes Care (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Helsingin Yliopisto
  • Juho Vainion Säätiö
  • Kuopion Yliopistollinen Sairaala
  • Novo Nordisk
  • Oulun Yliopisto
  • Novo Nordisk Fonden
  • Pirkanmaan Sairaanhoitopiiri
  • Tays
  • Diabetestutkimussäätiö
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
Keywords
lifestyle intervention, metabolic syndrome, impaired glucose tolerance, abdominal obesity, cardiovascular risk, Finnish Diabetes Prevention Study, type 2 diabetes prevention
MeSH terms
Blood Glucose, Diabetes Mellitus, Female, Finland, Follow-Up Studies, Glucose Tolerance Test, Humans, Life Style, Male, Middle Aged, Time Factors, Prevalence, Metabolic Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review