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The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions

Open access
Hamman, Richard F., Bell, Ronny A., Dabelea, Dana, D’Agostino, Ralph B., Dolan, Lawrence, Imperatore, Giuseppina, Lawrence, Jean M., Linder, Barbara, Marcovina, Santica M., Mayer-Davis, Elizabeth J., Pihoker, Catherine, Rodriguez, Beatriz L., Saydah, Sharon·2014·Diabetes Care

Abstract

The SEARCH for Diabetes in Youth (SEARCH) study was initiated in 2000, with funding from the Centers for Disease Control and Prevention and support from the National Institute of Diabetes and Digestive and Kidney Diseases, to address major knowledge gaps in the understanding of childhood diabetes. SEARCH is being conducted at five sites across the U.S. and represents the largest, most diverse study of diabetes among U.S. youth. An active registry of youth diagnosed with diabetes at age <20 years allows the assessment of prevalence (in 2001 and 2009), annual incidence (since 2002), and trends by age, race/ethnicity, sex, and diabetes type. Prevalence increased significantly from 2001 to 2009 for both type 1 and type 2 diabetes in most age, sex, and race/ethnic groups. SEARCH has also established a longitudinal cohort to assess the natural history and risk factors for acute and chronic diabetes-related complications as well as the quality of care and quality of life of persons with diabetes from diagnosis into young adulthood. Many youth with diabetes, particularly those from low-resourced racial/ethnic minority populations, are not meeting recommended guidelines for diabetes care. Markers of micro- and macrovascular complications are evident in youth with either diabetes type, highlighting the seriousness of diabetes in this contemporary cohort. This review summarizes the study methods, describes key registry and cohort findings and their clinical and public health implications, and discusses future directions.

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Metadata

Authors
Hamman, R. F., Bell, R. A., Dabelea, D., D’Agostino, R. B., Dolan, L., Imperatore, G., Lawrence, J. M., Linder, B., Marcovina, S. M., Mayer-Davis, E. J., Pihoker, C., Rodriguez, B. L., & Saydah, S.
Venue
Diabetes Care
Published
2014-11-08
Volume
37
Issue
12
Pages
3336-3344
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W2058667229
Cited by
619
References
17
FWCI
43.32
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions. https://app.cochat.ai/papers/10.2337/dc14-0574
The paper
Hamman, R. F., Bell, R. A., Dabelea, D., D’Agostino, R. B., Dolan, L., Imperatore, G., Lawrence, J. M., Linder, B., Marcovina, S. M., Mayer-Davis, E. J., Pihoker, C., Rodriguez, B. L., & Saydah, S. (2014). The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions. Diabetes Care. https://doi.org/10.2337/dc14-0574

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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