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Cited by 1,274Diabetes Treatment and ManagementDiabetes Management and ResearchDiabetes Management and Education

Diabetes in Older Adults

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Kirkman, M. Sue, Briscoe, Vanessa Jones, Clark, Nathaniel, Florez, Hermes, Haas, Linda B., Halter, Jeffrey B., Huang, Elbert S., Korytkowski, Mary T. +4 more·2012·Diabetes Care
DOI 10.2337/dc12-1801PMC PMC3507610
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Abstract

More than 25 % of the U.S. popula-tion aged $65 years has diabetes(1), and the aging of the overall population is a significant driver of the diabetes epidemic. Although the burden of diabetes is often described in terms of its impact on working-age adults, diabetes in older adults is linked to highermortality, reduced functional status, and increased risk of institutionalization (2). Older adults with diabetes are at substantial risk for both acute and chronic microvascular and car-diovascular complications of the disease. Despite having thehighest prevalence of diabetes of any age-group, older persons and/or those with multiple comorbidities have often been excluded from randomized

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  • A single end-stage chronic illness, such as stage 3-4 heart failure or oxygen-dependent lung disease, chronic kidney disease requiring dialysis, or uncontrolled metastatic cancer, may cause significant symptoms or impairment of functional status and significantly reduce life expectancy.

    “The presence of a single end-stage chronic illness, such as stage 3–4 heart failure or oxygen-dependent lung disease, chronic kidney disease requiring dialysis, or uncontrolled metastatic cancer, may cause significant symptoms or impairment of functional status and significantly reduce life expectancy.”

    From 13. Older Adults: Standards of Care in Diabetes—2026 (2026) · cites this paper as Kirkman et al. [5]

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  • Recent guidelines from the American Geriatrics Society stress the importance of an individualized treatment approach for diabetic adults who are frail or have multiple comorbid conditions.

    “Recent guidelines from the American Geriatrics Society stress the importance of an individualized treatment approach for diabetic adults who are frail or have multiple comorbid conditions.101”

    From Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group (2013) · cites this paper as [101]

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Cited by

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Authors
Kirkman, M. S., Briscoe, V. J., Clark, N., Florez, H., Haas, L. B., Halter, J. B., Huang, E. S., Korytkowski, M. T., Munshi, M. N., Odegard, P. S., Pratley, R. E., & Swift, C. S.
Affiliations
  • American Diabetes Association (US)
  • Vanderbilt University (US)
  • Diabetes Center of Cape Cod, Emerald Physicians, Hyannis, Massachusetts; the
  • University of Miami (US)
  • VA Puget Sound Health Care System (US)
  • University of Michigan (US)
  • University of Chicago (US)
  • University of Pittsburgh (US)
  • Joslin Diabetes Center (US)
  • University of Washington (US)
  • AdventHealth (US)
  • Kadlec Regional Medical Center (US)
Corresponding author
Kirkman, M. Sue
ORCID
Venue
Diabetes Care
Publisher
American Diabetes Association
Published
2012-11-14
Volume
35
Issue
12
Pages
2650-2664
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
DOI
10.2337/dc12-1801
PMC
PMC3507610
OpenAlex
W2114437291
Cited by
1,274
References
51
Citations by year
2026: 51 · 2025: 64 · 2024: 79 · 2023: 85 · 2022: 106 · 2021: 125 · 2020: 117 · 2019: 117 · 2018: 108 · 2017: 118 · 2016: 98 · 2015: 75 · 2014: 84 · 2013: 36 · 2012: 2
FWCI
50.56
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Diabetes Care (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders
  • National Institute on Aging (P30AG024824)
  • National Institute of Diabetes and Digestive and Kidney Diseases (P60DK20595, R01DK081796, P60DK020595, P30DK092949, P30DK092926)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords
diabetes in older adults, population aging, diabetes prevalence, mortality, functional status, institutionalization, microvascular complications, cardiovascular complications, comorbidities, exclusion from clinical trials
MeSH terms
Diabetes Mellitus, Diabetes Mellitus, Type 2, Female, Humans, Prediabetic State

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