Cited by 126Dermatology and Skin DiseasesPsychosomatic Disorders and Their TreatmentsPsoriasis: Treatment and Pathogenesis

Biopsychosocial mechanisms of chronic itch in patients with skin diseases: a review

Open access
Verhoeven, Elisabeth W.M., De Klerk, Suzanne, Kraaimaat, Floris W., Van de Kerkhof, Peter C.M., De Jong, Elke M.G.J., Evers, Andrea W.M.·2008·Acta Dermato Venereologica

Abstract

Itch is a major feature of many skin diseases, which adversely affects patient's quality of life. Besides disease severity, psychophysiological factors have been proposed to influence the itch sensation. In this review the evidence for a biopsychosocial model of itch is described, focusing in particular on evidence for the effects of personality characteristics, external stressors, cognitive, behavioural and social factors, and the possible mediating role of physiological processes. Research so far indicates that stressors may have a role in the itch sensation of patients with skin diseases. Furthermore, cognitive factors, such as helplessness and worrying, and the behavioural response of scratching have been indicated as possible worsening factors. Overall, findings are in favour of a biopsychosocial model for the itch sensation. However, there is a strong need for more, methodologically sound research in order fully to understand the processes underlying the itch sensation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.2340/00015555-0452

Cites

104 of 104 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The biopsychosocial model of chronic itch proposes that internal and external factors can lead to illness cognitions, social reactions, and behaviors, which can increase physiological responses leading to itch.

    “The biopsychosocial model of chronic itch (5) proposes that internal (e.g., personality) and external factors (e.g., stress) can lead to illness cognitions, social reactions, and behaviors, which can increase physiological responses (e.g., activation of certain brain areas) leading to itch (5).”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. van den Bergh O, Winters O, Devriese W, van Driest I. Sub- jective health complaints and objective health indicators. Scand J Psychol 2002; 43: 147-152.
  2. Evers AWM, Duller P, van de Kerkhof PCM, van der Valk PGM, de Jong EMGJ, Gerritsen MJP, et al. The impact of chronic skin diseases on daily life (ISDL): a generic and dermatology-specific health instrument. Br J Dermatol 2008; 158: 101-108

Cited by

Sorted by citations

Authors
Verhoeven, E. W. M., De Klerk, S., Kraaimaat, F. W., Van de Kerkhof, P. C. M., De Jong, E. M. G. J., & Evers, A. W. M.
Affiliations
Radboud University Medical Center (NL)
Corresponding author
Verhoeven, Elisabeth W.M.
Venue
Acta Dermato Venereologica
Published
2008-05-03
Volume
88
Issue
3
Pages
211-218
ISSN
  • 0001-5555 (ISSN-L)
  • 1651-2057
OpenAlex
W2156055510
Cited by
126
References
104
Citations by year
2026: 6 · 2025: 5 · 2024: 3 · 2023: 6 · 2022: 6 · 2021: 15 · 2020: 15 · 2019: 5 · 2018: 12 · 2017: 3 · 2016: 4 · 2015: 9 · 2014: 7 · 2013: 3 · 2012: 7
FWCI
1.03
Type
journal article
Language
en
Open access
Locations
  • Acta Dermato Venereologica (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
  • Radboud Repository (Radboud University) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
Keywords
chronic pruritus, pruritus, skin diseases, biopsychosocial model, stress, personality, helplessness, worry, scratching behavior, cognitive factors, social factors, quality of life
MeSH terms
Adaptation, Psychological, Chronic Disease, Helplessness, Learned, Humans, Models, Psychological, Personality, Pruritus, Quality of Life, Skin Diseases, Social Support, Stress, Psychological

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review