The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health
Open accessAbstract
degradation, toxicokinetics, genotoxicity as well as general issues relating to testing of nanomaterials. Depending on the initial tier results, studies may be needed to investigate reproductive and developmental toxicity, immunotoxicity, allergenicity, neurotoxicity, effects on gut microbiome and endocrine activity. The possible use of read-across to fill data gaps as well as the potential use of integrated testing strategies and the knowledge of modes/mechanisms of action are also discussed. The Guidance proposes approaches to risk characterisation and uncertainty analysis, and provides recommendations for further research in this area.
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Cites
A standardised static in vitro digestion method suitable for food – an international consensus
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Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms
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Deposition and biokinetics of inhaled nanoparticles
Geiser, M., & Kreyling, W. G. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-2 · Cited by 747
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Nano-enabled pesticides for sustainable agriculture and global food security
Wang, D., Saleh, N. B., Byro, A., Zepp, R., Sahle-Demessie, E., Luxton, T. P., Ho, K. T., Burgess, R. M., Flury, M., White, J. C., et al. (2022) · Nature Nanotechnology · doi:10.1038/s41565-022-01082-8 · Cited by 877
In vitro genotoxicity of polystyrene nanoparticles on the human fibroblast Hs27 cell line
Poma, A., Vecchiotti, G., Colafarina, S., Zarivi, O., Aloisi, M., Arrizza, L., Chichiriccò, G., & Di Carlo, P. (2019) · Nanomaterials · doi:10.3390/nano9091299 · Cited by 227
Natural Bioactive Compounds from Food Waste: Toxicity and Safety Concerns
Vilas-Boas, A. A., Pintado, M., & Oliveira, A. L. S. (2021) · Foods · doi:10.3390/foods10071564 · Cited by 217
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Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?
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Safety and regulatory issues of nanomaterials in foods
Tarhan, Ö. (2020) · Handbook of Food Nanotechnology · doi:10.1016/b978-0-12-815866-1.00016-9 · Cited by 23
Chen, T., Zhao, Y., Fan, Y., Dong, Y., & Gai, Z. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1501502 · Cited by 16
Biocompatibility and toxicity challenges of nanomaterials
Yaşayan, G., Alarcin, E., Avci-Adali, M., Ipek, T. C., Nejati, O., Özcan-Bülbül, E., Karslı, S., Bal-Öztürk, A., & Mostafavi, E. (2024) · Functionalized Nanomaterials for Cancer Research · doi:10.1016/b978-0-443-15518-5.00019-7 · Cited by 8
Metadata
- Authors
- EFSA Scientific Committee, Hardy, A., Benford, D., Halldorsson, T., Jeger, M. J., Knutsen, H. K., More, S., Naegeli, H., Noteborn, H., Ockleford, C., Ricci, A., Rychen, G., Schlatter, J. R., Silano, V., Solecki, R., Turck, D., Younes, M., Chaudhry, Q., Cubadda, F., Gott, D., Oomen, A., Weigel, S., Karamitrou, M., Schoonjans, R., & Mortensen, A.
- Venue
- EFSA Journal
- Publisher
- Wiley
- Published
- 2018-07
- Volume
- 16
- Issue
- 7
- Pages
- e05327-e05327
- ISSN
- 1831-4732 (ISSN-L)
- OpenAlex
- W2810972983
- Cited by
- 416
- References
- 4
- FWCI
- 44.63
- Type
- journal article
- Language
- en
- Open access
- gold
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