The neurobiology of the stress-resistant brain
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The 2010 Neurobiology of Stress Workshop brought together scientists from all over the world to share and discuss their results from studies examining the consequences of acute, repeated, and chronic stressor exposure on health and disease. Session IV entitled "The neurobiology of the stress-resistant brain" explored how we can intervene to promote stress resistance and stress resilience. Four scientists, who explore this topic from unique and convergent perspectives, presented their experimental results derived from studies in rat (Fleshner and Maier), non-human primates (Lyons), and human (Raskind). Summaries of each presentation, supporting publications, and overall take-home messages from the session are presented.
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Maier and colleagues view learned helplessness risk as highly dependent on the animal's control over stress, with resilience promoted by control over stress cessation.
“Maier and colleagues view the risk of learned helplessness to be highly dependent upon the animal’s own control over the stress, with resilience promoted by control over cessation of the stress (For review see 30).”
From Neurobiology of resilience (2012) · cites this paper as [30]
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- Authors
- Fleshner, M., Maier, S. F., Lyons, D. M., & Raskind, M. A.
- Affiliations
- University of Colorado Boulder (US)
- Stanford Medicine (US)
- University of Washington (US)
- Corresponding author
- Fleshner, Monika
- Venue
- Stress
- Publisher
- Informa UK Limited
- Published
- 2011-07-26
- Volume
- 14
- Issue
- 5
- Pages
- 498-502
- ISSN
- 1025-3890 (ISSN-L)
- 1607-8888
- PMC
- PMC3287388
- OpenAlex
- W2120959601
- Cited by
- 98
- References
- 36
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 4 · 2023: 15 · 2022: 6 · 2021: 6 · 2020: 2 · 2019: 10 · 2018: 6 · 2017: 5 · 2016: 9 · 2015: 5 · 2014: 4 · 2013: 11 · 2012: 4
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Stress (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (P50AG005136)
- National Institute of Mental Health (R01MH068283)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- stress tolerance, stress resilience, neurobiology of stress, chronic stress, repeated stress, acute stress, stress exposure, stress interventions, rat model, non-human primates, human stress
- MeSH terms
- Adaptation, Psychological, Animals, Brain, Helplessness, Learned, Humans, Motor Activity, Neurobiology, Prazosin, Saimiri, Stress, Physiological, Stress Disorders, Post-Traumatic, Stress, Psychological, Exercise, Receptors, Adrenergic, alpha-1, Rats
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