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Cited by 228

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin

Hurst, James K., Barrette, William C.·1989·Critical Reviews in Biochemistry and Molecular Biology

Abstract

Following a brief introduction of cellular response to stimulation comprising leukocyte activation, three major areas are discussed: (1) the neutrophil oxidase; (2) myeloperoxidase (MPO)-dependent oxidative microbicidal reactions; and (3) MPO-independent oxidative reactions. Topics included in section (A) are current views on the activation mechanism, redox composition, structural and topographic organization of the oxidase, and its respiratory products. In section (B), emphasis is placed on recent research on cidal mechanisms of HOCl, including the oxidative biochemistry of active chlorine compounds, identification of sites of lesions in bacteria, and attendant metabolic consequences. In section (C), we review the (bio)chemistry of H2O2 and .OH microbicidal reactions, with particular attention being given to addressing the controversial issue of probe methods to identify .OH radical and critical assessment of the recent proposal that MPO-independent killing arises from site-specific metal-catalyzed Fenton-type chemistry.

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Crossref · 10.3109/10409238909082555

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Metadata

Authors
Hurst, J. K., & Barrette, W. C.
Venue
Critical Reviews in Biochemistry and Molecular Biology
Published
1989-01
Volume
24
Issue
4
Pages
271-328
ISSN
  • 0045-6411 (ISSN-L)
  • 1040-9238
  • 1549-7798
OpenAlex
W2151840391
Cited by
228
References
10
FWCI
1.71
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin. https://app.cochat.ai/papers/10.3109/10409238909082555
The paper
Hurst, J. K., & Barrette, W. C. (1989). Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin. Critical Reviews in Biochemistry and Molecular Biology. https://doi.org/10.3109/10409238909082555

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.