Glutamatergic Modulators: The Future of Treating Mood Disorders?

Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice

Trivedi, M. H., Rush, A. J., Wisniewski, S. R., Nierenberg, A. A., Warden, D., Ritz, L., Norquist, G., Howland, R. H., Lebowitz, B., McGrath, P. J., et al. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.28 · Cited by 3,879 · see citing works

Antidepressant effects of ketamine in depressed patients

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00230-9 · Cited by 3,856 · see citing works

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.

Zarate, C. A., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.8.856 · Cited by 3,766 · see citing works

Evidence-based health policy—lessons from the Global Burden of Disease Study

Murray, C. J. L., & Lopez, A. D. (1996) · Science · doi:10.1126/science.274.5288.740 · Cited by 2,178 · see citing works

The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder

Judd, L. L., Akiskal, H. S., Schettler, P. J., Endicott, J., Maser, J., Solomon, D. A., Leon, A. C., Rice, J. A., & Keller, M. B. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.6.530 · Cited by 2,106 · see citing works

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Moghaddam, B., Adams, B., Verma, A., & Daly, D. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-08-02921.1997 · Cited by 1,793 · see citing works

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., Jin, L., Dykes Hoberg, M., Vidensky, S., Chung, D. S., et al. (2005) · Nature · doi:10.1038/nature03180 · Cited by 1,518 · see citing works

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

Maeng, S., Zarate, C. A., Du, J., Schloesser, R. J., McCammon, J., Chen, G., & Manji, H. K. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.05.028 · Cited by 1,103 · see citing works

Cingulate function in depression: a potential predictor of treatment response

Mayberg, H. S., Brannan, S. K., Mahurin, R. K., Jerabek, P. A., Brickman, J. S., Tekell, J. L., Silva, J. A., McGinnis, S., Glass, T. G., Martin, C. C., et al. (1997) · NeuroReport · doi:10.1097/00001756-199703030-00048 · Cited by 1,029 · see citing works

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

Sanacora, G., Zarate, C. A., Krystal, J. H., & Manji, H. K. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2462 · Cited by 894 · see citing works

Prevalence and Effects of Mood Disorders on Work Performance in a Nationally Representative Sample of U.S. Workers

Kessler, R. C., Akiskal, H. S., Ames, M., Birnbaum, H., Greenberg, P., .A, R. M., Jin, R., Merikangas, K. R., Simon, G. E., & Wang, P. S. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.9.1561 · Cited by 868 · see citing works

Prevalence and Effects of Mood Disorders on Work Performance in a Nationally Representative Sample of U.S. Workers

Kessler, R. C., Akiskal, H. S., Ames, M., Birnbaum, H., Greenberg, P., .A, R. M., Jin, R., Merikangas, K. R., Simon, G. E., & Wang, P. S. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.9.1561 · Cited by 868 · see citing works

Reduced Prefrontal Glutamate/Glutamine and γ-Aminobutyric Acid Levels in Major Depression Determined Using Proton Magnetic Resonance Spectroscopy

Hasler, G., van der Veen, J. W., Tumonis, T., Meyers, N., Shen, J., & Drevets, W. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.193 · Cited by 846 · see citing works

Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression

Sanacora, G., Gueorguieva, R. V., Epperson, C. N., Wu, Y., Appel, M., Rothman, D. L., Krystal, J. H., & Mason, G. F. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.705 · Cited by 796 · see citing works

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

Trullas, R., & Skolnick, P. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)90204-j · Cited by 785 · see citing works

Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression

aan het Rot, M., Collins, K. A., Murrough, J. W., Perez, A. M., Reich, D. L., Charney, D. S., & Mathew, S. J. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.08.038 · Cited by 690 · see citing works

Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

Choudary, P. V., Molnar, M., Evans, S. J., Tomita, H., Li, J., Vawter, M. P., Myers, R., Bunney, W. E., Akil, H., Watson, S. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507901102 · Cited by 653 · see citing works

Anterior Cingulate Activity as a Predictor of Degree of Treatment Response in Major Depression: Evidence From Brain Electrical Tomography Analysis

Pizzagalli, D., Pascual-Marqui, R. D., Nitschke, J. B., Oakes, T. R., Larson, C. L., Abercrombie, H. C., Schaefer, S. M., Koger, J. V., Benca, R. M., & Davidson, R. J. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.405 · Cited by 630 · see citing works

Increased Levels of Glutamate in Brains from Patients with Mood Disorders

Hashimoto, K., Sawa, A., & Iyo, M. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.017 · Cited by 609 · see citing works

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

Banasr, M., & Duman, R. S. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.008 · Cited by 606 · see citing works

Rapid Resolution of Suicidal Ideation After a Single Infusion of an <i>N</i> -Methyl- <scp>D</scp> -Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

DiazGranados, N., Ibrahim, L. A., Brutsche, N. E., Ameli, R., Henter, I. D., Luckenbaugh, D. A., Machado-Vieira, R., & Zarate, C. A. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05327blu · Cited by 564 · see citing works

Two-Year Syndromal and Functional Recovery in 219 Cases of First-Episode Major Affective Disorder With Psychotic Features

Tohen, M. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.2.220 · Cited by 525 · see citing works

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

Preskorn, S., Baker, B., Kolluri, S., Menniti, F. S., Krams, M., & Landen, J. W. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31818a6cea · Cited by 522 · see citing works

Memories of NMDA receptors and LTP

Collingridge, G. L., & Bliss, T. V. P. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)80016-u · Cited by 493 · see citing works

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus

Garcia, L. S. B., Comim, C. M., Valvassori, S. S., Réus, G. Z., Barbosa, L. M., Andreazza, A. C., Stertz, L., Fries, G. R., Gavioli, E. C., Kapczinski, F., et al. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.07.027 · Cited by 454 · see citing works

Abnormal Glutamate Receptor Expression in the Medial Temporal Lobe in Schizophrenia and Mood Disorders

Beneyto, M., Kristiansen, L. V., Oni-Orisan, A., McCullumsmith, R. E., & Meador-Woodruff, J. H. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301312 · Cited by 408 · see citing works

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine: A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity

Cosford, N. D. P., Tehrani, L. R., Roppe, J. R., Schweiger, E. J., Smith, N. D., Anderson, J., Bristow, L. J., Brodkin, J. D., Jiang, X., McDonald, I. A., et al. (2002) · Journal of Medicinal Chemistry · doi:10.1021/jm025570j · Cited by 397 · see citing works

A Double-Blind, Placebo-Controlled Study of Memantine in the Treatment of Major Depression

Zarate, C. A., Singh, J. B., Quiroz, J. A., De Jesus, G., Denicoff, K. K., Luckenbaugh, D. A., Manji, H. K., & Charney, D. S. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.153 · Cited by 387 · see citing works

Neuroplasticity Mediated by Altered Gene Expression

McClung, C. A., & Nestler, E. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301544 · Cited by 347 · see citing works

Impairments of Neuroplasticity and Cellular Resilience in Severe Mood Disorders: Implications for the Development of Novel Therapeutics

Manji, H. K., Duman, R. S., Duman, F. A. R. S., & PhD (2025) · Psychopharmacology Bulletin · doi:10.64719/pb.4260 · Cited by 330 · see citing works

Prediction of Antidepressant Effects of Sleep Deprivation by Metabolic Rates in the Ventral Anterior Cingulate and Medial Prefrontal Cortex

Wu, J. C., Buchsbaum, M. S., Gillin, J. C., Tang, C. Y., Cadwell, S., Wiegand, M. H., Najafi, A., Klein, E., Hazen, K., & Bunney, W. E. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.8.1149 · Cited by 327 · see citing works

An Open-Label Trial of Riluzole in Patients With Treatment-Resistant Major Depression

Zarate, C. A., Payne, J. L., Quiroz, J. A., Sporn, J., Denicoff, K. K., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.1.171 · Cited by 324 · see citing works

Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: An open-label trial

Coric, V., Taskiran, S., Pittenger, C., Wasylink, S., Mathalon, D. H., Valentine, G., Saksa, J., Wu, Y.-T., Gueorguieva, R., Sanacora, G., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.043 · Cited by 314 · see citing works

Cure therapeutics and strategic prevention: raising the bar for mental health research

Insel, T. R., & Scolnick, E. M. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001777 · Cited by 313 · see citing works

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation

Hashimoto, R., Hough, C. J., Nakazawa, T., Yamamoto, T. S., & Chuang, D. (2002) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00728.x · Cited by 310 · see citing works

Remission Rates Following Antidepressant Therapy With Bupropion or Selective Serotonin Reuptake Inhibitors: A Meta-Analysis of Original Data From 7 Randomized Controlled Trials

Thase, M. E., Haight, B. R., Richard, N., Rockett, C. B., Mitton, M., Modell, J. G., VanMeter, S., Harriett, A. E., & Wang, Y. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0803 · Cited by 304 · see citing works

Increased Anterior Cingulate Cortical Activity in Response to Fearful Faces: A Neurophysiological Biomarker that Predicts Rapid Antidepressant Response to Ketamine

Salvadore, G., Cornwell, B. R., Colon-Rosario, V., Coppola, R., Grillon, C., Zarate, C. A., & Manji, H. K. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.08.014 · Cited by 277 · see citing works

Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression

Papp, M., & Moryl, E. (1994) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)90516-9 · Cited by 272 · see citing works

Antidepressant and anxiolytic‐like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

Cryan, J. F., Kelly, P. H., Neijt, H. C., Sansig, G., Flor, P. J., & van der Putten, H. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02667.x · Cited by 266 · see citing works

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

Zarate, C. A., Quiroz, J. A., Singh, J. B., Denicoff, K. D., Jesus, G. D., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.023 · Cited by 257 · see citing works

Cellular Plasticity Cascades in the Pathophysiology and Treatment of Bipolar Disorder

Schloesser, R. J., Huang, J. Y., Klein, P. S., & Manji, H. K. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301575 · Cited by 256 · see citing works

Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: A systematic review of the in vivo proton magnetic resonance spectroscopy findings

Yildiz-Yesiloglu, A., & Ankerst, D. P. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.03.012 · Cited by 253 · see citing works

Response and remission rates in different subpopulations with major depressive disorder administered venlafaxine, selective serotonin reuptake inhibitors, or placebo

Entsuah, A. R., Huang, H., & Thase, M. E. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n1106 · Cited by 245 · see citing works

Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments.

Paul, I. A., Nowak, G., Layer, R. T., Popik, P., & Skolnick, P. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38715-x · Cited by 241 · see citing works

Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses

Law, A. J., & Deakin, J. F. W. (2001) · Neuroreport · doi:10.1097/00001756-200109170-00043 · Cited by 227 · see citing works

AMPA Receptor Potentiators for the Treatment of CNS Disorders

O’Neill, M. J., Bleakman, D., Zimmerman, D. M., & Nisenbaum, E. S. (2004) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1568007043337508 · Cited by 223 · see citing works

Riluzole Enhances Glutamate Uptake in Rat Astrocyte Cultures

Frizzo, M. E., Dall’Onder, L. P., Dalcin, K. B., & Souza, D. O. (2004) · Cellular and Molecular Neurobiology · doi:10.1023/b:cemn.0000012717.37839.07 · Cited by 213 · see citing works

Genetic Markers of Suicidal Ideation Emerging During Citalopram Treatment of Major Depression

Laje, G., Paddock, S., Manji, H. K., Rush, A. J., Wilson, A. F., Charney, D. S., & McMahon, F. J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06122018 · Cited by 213 · see citing works

Genetic Inactivation of the NMDA Receptor NR2A Subunit has Anxiolytic- and Antidepressant-Like Effects in Mice

Boyce‐Rustay, J. M., & Holmes, A. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301039 · Cited by 209 · see citing works

LY354740, an mGlu2/3 Receptor Agonist as a Novel Approach to Treat Anxiety/Stress

Schoepp, D. D., Wright, R. A., Levine, L. R., Gaydos, B. L., & Potter, W. Z. (2003) · Stress · doi:10.1080/1025389031000146773 · Cited by 207 · see citing works

Functional impairment in the remission phase of bipolar disorder

Fagiolini, A. M., Kupfer, D. J., Masalehdan, A., Scott, J., Houck, P. R., & Frank, E. (2005) · Bipolar Disorders · doi:10.1111/j.1399-5618.2005.00207.x · Cited by 206 · see citing works

Preliminary Evidence of Riluzole Efficacy in Antidepressant-Treated Patients with Residual Depressive Symptoms

Sanacora, G., Kendell, S. F., Levin, Y., Simen, A. A., Fenton, L. R., Coric, V., & Krystal, J. H. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.037 · Cited by 199 · see citing works

Factors associated with treatment nonadherence among US bipolar disorder patients

Baldessarini, R. J., Perry, R., & Pike, J. (2008) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.908 · Cited by 198 · see citing works

Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid.

Nowak, G., Trullás, R., Layer, R. T., Skolnick, P., & Paul, I. A. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38235-2 · Cited by 196 · see citing works

Rapid Onset of Antidepressant Action: A New Paradigm in the Research and Treatment of Major Depressive Disorder

Machado-Vieira, R., Salvadore, G., Luckenbaugh, D. A., Manji, H. K., & Zarate, C. A. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0610 · Cited by 195 · see citing works

Association of GRIK4 With Outcome of Antidepressant Treatment in the STAR*D Cohort

Paddock, S., Laje, G., Charney, D. S., Rush, A. J., Wilson, A. F., Sorant, A. J. M., Lipsky, R. H., Wisniewski, S. R., Manji, H., & McMahon, F. J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111790 · Cited by 192 · see citing works

Small-Dose Ketamine Improves the Postoperative State of Depressed Patients

Kudoh, A., Takahira, Y., Katagai, H., & Takazawa, T. (2002) · Anesthesia &amp; Analgesia · doi:10.1097/00000539-200207000-00020 · Cited by 189 · see citing works

Family History of Alcohol Dependence and Initial Antidepressant Response to an N-methyl-D-aspartate Antagonist

Phelps, L. E., Brutsché, N. E., Moral, J. R., Luckenbaugh, D. A., Manji, H. K., & Zarate, C. A. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.029 · Cited by 188 · see citing works

Treatment-resistant bipolar disorder

Gitlin, M. J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001793 · Cited by 182 · see citing works

Abnormalities of the NMDA Receptor and Associated Intracellular Molecules in the Thalamus in Schizophrenia and Bipolar Disorder

Clinton, S. M., & Meador‐Woodruff, J. H. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300451 · Cited by 177 · see citing works

Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data

Black, M. D. (2005) · Psychopharmacology · doi:10.1007/s00213-004-2065-6 · Cited by 176 · see citing works

(R, S)-4-Phosphonophenylglycine, a Potent and Selective Group III Metabotropic Glutamate Receptor Agonist, Is Anticonvulsive and Neuroprotective In Vivo

Gasparini, F., Bruno, V., Battaglia, G., Lukic, S., Leonhardt, T., Inderbitzin, W., Laurie, D., Sommer, B., Varney, M. A., Hess, S. D., et al. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38321-1 · Cited by 174 · see citing works

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

Shaltiel, G., Maeng, S., Malkesman, O., Pearson, B., Schloesser, R. J., Tragon, T., Rogawski, M., Gasior, M., Luckenbaugh, D., Chen, G., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.20 · Cited by 173 · see citing works

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders

Machado-Vieira, R., Manji, H. K., & Zarate, C. A. (2009) · The Neuroscientist · doi:10.1177/1073858409336093 · Cited by 171 · see citing works

Enhanced anxiety, depressive‐like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1)

Tordera, R. M., Totterdell, S., Wojcik, S. M., Brose, N., Elizalde, N., Lasheras, B., & del Rı́o, J. A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05259.x · Cited by 169 · see citing works

DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling

Wilson, G. M., Flibotte, S., Chopra, V. S., Melnyk, B. L., Honer, W. G., & Holt, R. A. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddi489 · Cited by 167 · see citing works

Association of GRIK4 With Outcome of Antidepressant Treatment in the STAR*D Cohort

Ballenger, J. C. (2009) · Yearbook of Psychiatry and Applied Mental Health · doi:10.1016/s0084-3970(08)79086-8 · Cited by 167 · see citing works

Regulation of Cellular Plasticity Cascades in the Pathophysiology and Treatment of Mood Disorders

Zarate, C. A., Du, J., Quiroz, J. A., GRAY, N. A., Denicoff, K. D., Singh, J., Charney, D. S., & Manji, H. K. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.017 · Cited by 164 · see citing works

Metabotropic Glutamate 5 Receptor Antagonism Is Associated with Antidepressant-Like Effects in Mice

Li, X., Need, A. B., Baez, M., & Witkin, J. M. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.103143 · Cited by 163 · see citing works

Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder

McCullumsmith, R. E., Kristiansen, L. V., Beneyto, M., Scarr, E., Dean, B., & Meador‐Woodruff, J. H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.011 · Cited by 157 · see citing works

Potential Antidepressive Properties of Amantadine, Memantine and Bifemelane

Moryl, E., Danysz, W., & Quack, G. (1993) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1993.tb01351.x · Cited by 157 · see citing works

Brain-Derived Neurotrophic Factor and Initial Antidepressant Response to an<i>N</i>-Methyl-<scp>D</scp>-Aspartate Antagonist

Machado-Vieira, R., Yuan, P., Brutsche, N., DiazGranados, N., Luckenbaugh, D., Manji, H. K., & Zarate, C. A. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04659 · Cited by 155 · see citing works

NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder

Toro, C. T., & Deakin, J. F. W. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.07.003 · Cited by 151 · see citing works

Antidepressant-Like Effects of Ceftriaxone in Male C57BL/6J Mice

Mineur, Y. S., Picciotto, M. R., & Sanacora, G. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.037 · Cited by 150 · see citing works

The NR1 subunit of the glutamate/NMDA receptor in the superior temporal cortex in schizophrenia and affective disorders

Nudmamud‐Thanoi, S., & Reynolds, G. P. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.09.035 · Cited by 147 · see citing works

AMPA receptor subunit 1 (GluR‐A) knockout mice model the glutamate hypothesis of depression

Chourbaji, S., Vogt, M. A., Fumagalli, F., Sohr, R., Frasca, A., Brandwein, C., Hörtnagl, H., Riva, M. A., Sprengel, R., & Gass, P. (2008) · The FASEB Journal · doi:10.1096/fj.08-106450 · Cited by 144 · see citing works

Elevated levels of NR2A and PSD-95 in the lateral amygdala in depression

Karolewicz, B., Szebeni, K., Gilmore, T., Maciąg, D., Stockmeier, C. A., & Ordway, G. A. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145708008985 · Cited by 144 · see citing works

Altered NMDA Glutamate Receptor Antagonist Response in Individuals With a Family Vulnerability to Alcoholism

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Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder

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