Imaging Features of Acute Encephalopathy in Patients with COVID-19: A Case Series
Open accessAbstract
Coronavirus disease 2019 was declared a global pandemic by the World Health Organization on March 11, 2020. There is a scarcity of data on coronavirus disease 2019-related brain imaging features. We present 5 cases that illustrate varying imaging presentations of acute encephalopathy in patients with coronavirus disease 2019. MR features include leukoencephalopathy, diffusion restriction that involves the GM and WM, microhemorrhages, and leptomeningitis. We believe it is important for radiologists to be familiar with the neuroradiologic imaging spectrum of acute encephalopathy in the coronavirus disease 2019 population.
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Most studies on cognitive changes following SARS-CoV-2 infection focused on acute changes, mainly acute encephalopathy.
“Most studies on cognitive changes following SARS-CoV-2 infection focused on acute changes, mainly acute encephalopathy [137–139].”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [139]
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- Authors
- Kihira, S., Delman, B. N., Belani, P., Stein, L., Aggarwal, A., Rigney, B., Schefflein, J., Doshi, A. H., & Pawha, P. S.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- ORCID
- Venue
- American Journal of Neuroradiology
- Published
- 2020-08-13
- Volume
- 41
- Issue
- 10
- Pages
- 1804-1808
- ISSN
- 0195-6108 (ISSN-L)
- 1936-959X
- PMC
- PMC7661067
- OpenAlex
- W3049537531
- Cited by
- 38
- References
- 26
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 5 · 2022: 11 · 2021: 15 · 2020: 2
- FWCI
- 3.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- American Journal of Neuroradiology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Psychiatry and Mental health › Neurological Complications and Syndromes
- Keywords
- COVID-19 pandemic, acute encephalopathy, SARS-CoV-2, leukoencephalopathy, restricted diffusion, microhemorrhages, leptomeningitis, brain MRI findings
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Acute Disease, Adult, Brain Diseases, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Leukoencephalopathies, Pandemics
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