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Dopamine: A Modulator of Circadian Rhythms in the Central Nervous System
Open accessAbstract
Circadian rhythms are daily rhythms that regulate many biological processes - from gene transcription to behavior - and a disruption of these rhythms can lead to a myriad of health risks. Circadian rhythms are entrained by light, and their 24-h oscillation is maintained by a core molecular feedback loop composed of canonical circadian ("clock") genes and proteins. Different modulators help to maintain the proper rhythmicity of these genes and proteins, and one emerging modulator is dopamine. Dopamine has been shown to have circadian-like activities in the retina, olfactory bulb, striatum, midbrain, and hypothalamus, where it regulates, and is regulated by, clock genes in some of these areas. Thus, it is likely that dopamine is essential to mechanisms that maintain proper rhythmicity of these five brain areas. This review discusses studies that showcase different dopaminergic mechanisms that may be involved with the regulation of these brain areas' circadian rhythms. Mechanisms include how dopamine and dopamine receptor activity directly and indirectly influence clock genes and proteins, how dopamine's interactions with gap junctions influence daily neuronal excitability, and how dopamine's release and effects are gated by low- and high-pass filters. Because the dopamine neurons described in this review also release the inhibitory neurotransmitter GABA which influences clock protein expression in the retina, we discuss articles that explore how GABA may contribute to the actions of dopamine neurons on circadian rhythms. Finally, to understand how the loss of function of dopamine neurons could influence circadian rhythms, we review studies linking the neurodegenerative disease Parkinson's Disease to disruptions of circadian rhythms in these five brain areas. The purpose of this review is to summarize growing evidence that dopamine is involved in regulating circadian rhythms, either directly or indirectly, in the brain areas discussed here. An appreciation of the growing evidence of dopamine's influence on circadian rhythms may lead to new treatments including pharmacological agents directed at alleviating the various symptoms of circadian rhythm disruption.
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“SCN neuronal firing is also reduced in these mice from young adulthood and progressively worsens with age, suggesting a weakened circadian pacemaker276 and a potential loss of dopaminergic modulation of circadian rhythms via midbrain, striatal and SCN circuits277,278.”
From Rhythms of life: circadian disruption and brain disorders across the lifespan (2019) · cites this paper as [278]
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Citations
Cites
The physiology, signaling, and pharmacology of dopamine receptors
Beaulieu, J.-M., & Gainetdinov, R. R. (2011) · Pharmacological Reviews · doi:10.1124/pr.110.002642 · Cited by 2,763
Prolactin: structure, function, and regulation of secretion
Freeman, M. E., Kanyicska, B., Lerant, A., & Nagy, G. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1523 · Cited by 2,457
Central and Peripheral Circadian Clocks in Mammals
Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265
The brain reward circuitry in mood disorders
Russo, S. J., & Nestler, E. J. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3381 · Cited by 1,870
Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
Chaudhuri, К. R., & Schapira, A. H. V. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70068-7 · Cited by 1,818
Smell identification ability: changes with age.
Doty, R. L., Shaman, P., Applebaum, S. L., Giberson, R. S., Siksorski, L., & Rosenberg, L. (1984) · Science · doi:10.1126/science.6505700 · Cited by 1,357
Central projections of melanopsin‐expressing retinal ganglion cells in the mouse
Hattar, S., Kumar, M., Park, A., Tong, P., Tung, J., Yau, K., & Berson, D. M. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.20970 · Cited by 996
Genetic Animal Models of Parkinson's Disease
Dawson, T. M., Ko, H. S., & Dawson, V. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.034 · Cited by 866
Doty, R. L., Deems, D. A., & Stellar, S. (1988) · Neurology · doi:10.1212/wnl.38.8.1237 · Cited by 838
Witkovsky, P. (2004) · Documenta Ophthalmologica · doi:10.1023/b:doop.0000019487.88486.0a · Cited by 811
Research works printed but not linked: 4
- Dominguez-Rodriguez, 2009, Disruption of normal circadian rhythms and cardiovascular events., Heart Metab., 44, 11
- Golgi, 1875, Sulla fina struttura dei bulbi olfactorii., Riv. Sper. Freniatr. Med. Leg., 1, 405
- Nolte, 2009, The Human Brain: An Introduction to its Functional Anatomy
- Rivkees, 1997, Functional D1 and D5 dopamine receptors are expressed in the suprachiasmatic, supraoptic, and paraventricular nuclei of primates., Synapse, 26, 1, 10.1002/(SICI)1098-2396(199705)26:11::AID-SYN13.0.CO;2-D · DOI
Cited by
Sorted by citations
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Nassan, M. M., & Videnović, A. (2021) · Nature Reviews Neurology · doi:10.1038/s41582-021-00577-7 · Cited by 266
Circadian rhythms, refractive development, and myopia
Chakraborty, R., Ostrin, L. A., Nickla, D. L., Iuvone, P. M., Pardue, M. T., & Stone, R. A. (2018) · Ophthalmic and Physiological Optics · doi:10.1111/opo.12453 · Cited by 235
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Hong, G., Tian-ming Fu, B., Qiao, M., Viveros, R. D., Yang, X., Zhou, T., Lee, J. M., Park, H., Sanes, J. R., & Lieber, C. M. (2018) · Science · doi:10.1126/science.aas9160 · Cited by 171
Printing Flexible and Hybrid Electronics for Human Skin and Eye‐Interfaced Health Monitoring Systems
Kim, K., Kim, B., & Lee, C. H. (2019) · Advanced Materials · doi:10.1002/adma.201902051 · Cited by 148
Lee, H. R., Lee, D., & Oh, J. H. (2021) · Advanced Materials · doi:10.1002/adma.202100119 · Cited by 122
Quagliariello, A., CHIERICO, F. D., Russo, A., Reddel, S., Conte, G., Lopetuso, L. R., Ianiro, G., Dallapiccola, B., Cardona, F., Gasbarrini, A., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00675 · Cited by 119
Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2
Davinelli, S., Medoro, A., Savino, R., & Scapagnini, G. (2024) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-024-01487-0 · Cited by 135
Sleep and circadian rhythms in Parkinson’s disease and preclinical models
Hunt, J., Coulson, E. J., Rajnarayanan, R. V., Oster, H., Videnović, A., & Rawashdeh, O. (2022) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00504-w · Cited by 118
Recent Advances in the Etiology and Treatment of Burning Mouth Syndrome
Ritchie, A. C., & Kramer, J. M. (2018) · Journal of Dental Research · doi:10.1177/0022034518782462 · Cited by 85
Impaired Glymphatic and Meningeal Lymphatic Functions in Patients with Chronic Migraine
Wu, C., Chang, F., Wang, Y.-F., Lirng, J., Wu, H., Pan, L. H., Wang, S., & Chen, S. (2023) · Annals of Neurology · doi:10.1002/ana.26842 · Cited by 80
The Effects of Light and the Circadian System on Rhythmic Brain Function
von Gall, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052778 · Cited by 82
Mi, H., Jing, X., Thomsom, J. A., & Turng, L. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb00654g · Cited by 75
The role of dopamine in overcoming aversion with exercise
Greenwood, B. N. (2018) · Brain Research · doi:10.1016/j.brainres.2018.08.030 · Cited by 81
Early-stage visual perception impairment in schizophrenia, bottom-up and back again
Adámek, P., Langová, V., & Horáček, J. (2022) · Schizophrenia · doi:10.1038/s41537-022-00237-9 · Cited by 88
Curtis, W. M., Seeds, W. A., Mattson, M. P., & Bradshaw, P. C. (2022) · Cells · doi:10.3390/cells11152416 · Cited by 72
Roles of clock genes in the pathogenesis of Parkinson's disease
Shkodina, A. D., Tan, S. C., Hasan, M. M., Abdelgawad, M., Chopra, H., Bilal, M., Boiko, D. I., Tarianyk, K. А., & Alexiou, A. T. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101554 · Cited by 67
Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron
Galliano, E., Franzoni, E., Breton, M., Chand, A. N., Byrne, D. J., Murthy, V. N., & Grubb, M. S. (2018) · eLife · doi:10.7554/elife.32373 · Cited by 54
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Alex, A., Luo, Q., Mathew, D., Di, R., & Bhatwadekar, A. D. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.6.46 · Cited by 48
Circadian Rhythm Abnormalities in Parkinson’s Disease from Humans to Flies and Back
Lazzari, F. D., Bisaglia, M., Zordan, M. A., & Sandrelli, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123911 · Cited by 46
Braz, C. U., Rowan, T. N., Schnabel, R. D., & Decker, J. E. (2021) · Scientific Reports · doi:10.1038/s41598-021-92455-x · Cited by 47
Peripheral Clock System Abnormalities in Patients With Parkinson’s Disease
Li, T., Cheng, C., Jia, C., Leng, Y., Jin, Q., Yu, H., Liu, Y., Wang, N., Yang, Y., Al‐Nusaif, M., et al. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.736026 · Cited by 41
Vieira, R. S. F., Venâncio, C. A. S., & Félix, L. M. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08412-0 · Cited by 39
Liu, Y., Niu, L., Liu, X., Cheng, C., & Le, W. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00711-x · Cited by 39
Boiko, D. I., Chopra, H., Bilal, M., Kydon, P. V., Herasymenko, L. O., Rud, V. O., Боднарь, Л. А., Vasylyeva, G. Y., Isakov, R. І., Zhyvotovska, L. V., et al. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.12.002 · Cited by 39
Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation
Brami‐Cherrier, K., Lewis, R. G., Cervantes, M., Liu, Y., Tognini, P., Baldi, P., Sassone‐Corsi, P., & Borrelli, E. (2020) · Nature Communications · doi:10.1038/s41467-020-18200-6 · Cited by 36
Mesencephalic and extramesencephalic dopaminergic systems in Parkinson’s disease
Geibl, F. F., Henrich, M. T., & Oertel, W. H. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-01970-9 · Cited by 34
Boxelaere, M. V., Clements, J., Callaerts, P., D’Hooge, R., & Callaerts‐Vegh, Z. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188537 · Cited by 34
Dopamine Signaling in Circadian Photoentrainment: Consequences of Desynchrony.
Grippo, R. M., & Güler, A. D. (2019) · PubMed Central · Cited by 29
Samizadeh, M., Fallah, H., Toomarisahzabi, M., Rezaei, F., Rahimi-Danesh, M., Akhondzadeh, S., & Vaseghi, S. (2023) · Brain Sciences · doi:10.3390/brainsci13060914 · Cited by 33
Ontogenetic rules for the molecular diversification of hypothalamic neurons
Benevento, M., Hökfelt, T. G. M., & Harkany, T. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00615-3 · Cited by 28
Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo
Moran, A. L., Fehilly, J. D., Jones, D. F., Collery, R. F., & Kennedy, B. N. (2022) · The FASEB Journal · doi:10.1096/fj.202200990rr · Cited by 27
Fighting Against the Clock: Circadian Disruption and Parkinson’s Disease
Chen, Y.-C., Wang, W., Lewis, S. J. G., & Wu, S. (2023) · Journal of Movement Disorders · doi:10.14802/jmd.23216 · Cited by 26
Disrupted Circadian Rhythms and Substance Use Disorders: A Narrative Review
Sharma, P., & Nelson, R. J. (2024) · Clocks & Sleep · doi:10.3390/clockssleep6030030 · Cited by 29
Dopamine systems and biological rhythms: Let’s get a move on
Tang, Q., Assali, D. R., Güler, A. D., & Steele, A. D. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.957193 · Cited by 28
Li, L., Zhao, Z., Ma, J., Zheng, J., Huang, S., Hu, S., Gu, Q., & Chen, S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00505 · Cited by 27
Abdul, F., Sreenivas, N., Kommu, J. V. S., Banerjee, M., Berk, M., Maes, M. H. J., Leboyer, M., & Debnath, M. (2021) · Reviews in the Neurosciences · doi:10.1515/revneuro-2021-0022 · Cited by 26
Luo, S., Zhang, Y., Ezrokhi, M., Li, Y., Tsai, T., & Cincotta, A. H. (2017) · Journal of Neuroendocrinology · doi:10.1111/jne.12563 · Cited by 24
Guo, D., Zhang, S., Sun, H., Xu, X., Hao, Z., Mu, C., Xu, X., Wang, G., & Ren, H. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra117.000618 · Cited by 26
Coliță, C.-I., Hermann, D. M., Fîlfan, M., Coliță, D., Doeppner, T. R., Tica, O. S., Glăvan, D., & Popa‐Wagner, A. (2024) · Clocks & Sleep · doi:10.3390/clockssleep6040043 · Cited by 23
Illuminating and Sniffing Out the Neuromodulatory Roles of Dopamine in the Retina and Olfactory Bulb
Korshunov, K. S., Blakemore, L. J., & Trombley, P. Q. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00275 · Cited by 26
Self-citationPEDOT/CNT Flexible MEAs Reveal New Insights into the Clock Gene's Role in Dopamine Dynamics
Wu, B., Castagnola, E., McClung, C. A., & Cui, X. T. (2024) · Advanced Science · doi:10.1002/advs.202308212 · Cited by 22
Circadian rhythm disruption: a potential trigger in Parkinson’s disease pathogenesis
Xu, K., Zhang, Y., Shi, Y. X., Zhang, Y., Zhang, C., Wang, T., Lv, P., Bai, Y., & Wang, S. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1464595 · Cited by 24
The dopaminergic control of Cushing’s syndrome
Pivonello, R., Pivonello, C., Simeoli, C., Martino, M. C. D., & Colao, A. (2022) · Journal of Endocrinological Investigation · doi:10.1007/s40618-021-01661-x · Cited by 22
Sleep and circadian rhythms in α‐synucleinopathies—Perspectives for disease modification
Kunz, D., Oster, H., Rawashdeh, O., Neumann, W., Münte, T. F., & Berg, D. (2023) · Acta Physiologica · doi:10.1111/apha.13966 · Cited by 24
Park, K. W., Jo, S., Lee, S. H., Hwang, Y. S., Lee, D., Ryu, H., & Chung, S. J. (2020) · Journal of Movement Disorders · doi:10.14802/jmd.20055 · Cited by 20
Lin, L., Gupta, S. N., Zheng, W., Si, K., & Zhu, J. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00960-8 · Cited by 20
Characterization of retinal function and structure in the MPTP murine model of Parkinson’s disease
Tran, K. K. N., Wong, V. H. Y., Lim, J. K. H., Shahandeh, A., Hoang, A., Finkelstein, D. I., Bui, B. V., & Nguyen, C. T. O. (2022) · Scientific Reports · doi:10.1038/s41598-022-11495-z · Cited by 20
Palamarchuk, I. S., Slavich, G. M., Vaillancourt, T., & Rajji, T. K. (2023) · BMC Neuroscience · doi:10.1186/s12868-023-00831-2 · Cited by 26
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“, 2016) and exhibit circadian oscillation (Korshunov et al., 2017), the time of testing did not appear to be a significant contributor to our findings.”
BackgroundCircadian clock genes and insomnia: molecular mechanisms and therapeutic implications
Ren, Q., Gu, M., & Xu, F. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2576643 · Cited by 22
Shen, H., Ding, L., He, K., Zheng, B., Liu, D., Zhang, M., Yang, Y., Mo, Y., Li, H., Cai, Y., et al. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04487-w · Cited by 18
Bauer, N., Liu, D., Nguyen, T., & Wang, B. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00742 · Cited by 19
Capella, M. D. M., Martinez-Nicolas, A., & Adan, A. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00373 · Cited by 17
Mirian, M., Hariri, A., Yadollahi, M., & Kohandel, M. (2022) · Cancers · doi:10.3390/cancers14061578 · Cited by 17
Sobriety and Satiety: Is NAD+ the Answer?
Braidy, N., Villalva, M. D., & van Eeden, S. (2020) · Antioxidants · doi:10.3390/antiox9050425 · Cited by 17
Saloner, R., Cherner, M., Sundermann, E. E., Watson, C. W., Iudicello, J. E., Letendre, S. L., Kumar, A. M., & Ellis, R. J. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113269 · Cited by 16
Marano, M., Rosati, J. D., Magliozzi, A., Casamassa, A., Rappa, A., Sergi, G., Iannizzotto, M., Yekutieli, Z., Vescovi, A. L., & Lazzaro, V. D. (2023) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2023.100094 · Cited by 16
Gorgol, J., Waleriańczyk, W., & Randler, C. (2023) · Chronobiology International · doi:10.1080/07420528.2023.2212043 · Cited by 15
Circadian neurogenetics and its implications in neurophysiology, behavior, and chronomedicine
Naveed, M., Chao, O. Y.-H., Hill, J. W., Yang, Y., Huston, J. P., & Cao, R. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105523 · Cited by 16
Liang, F., Chen, C., Li, Y.-P., Ke, Y., Ho, E., Jeng, C., Lin, C., & Chen, S. (2022) · Journal of Parkinson s Disease · doi:10.3233/jpd-223431 · Cited by 14
Azargoonjahromi, A., & Bahrampour, Z. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106690 · Cited by 21
Ziegler, M., Kaiser, A., Igel, C., Geissler, J. M., Mechler, K., Holz, N. E., Becker, K., Döpfner, M., Romanos, M., Brandeis, D., et al. (2021) · Brain Sciences · doi:10.3390/brainsci11121564 · Cited by 15
Neuropharmacologic modulation of the melatonergic system
Aykan, U., Güvel, M. C., Paykal, G., & Uluoğlu, C. (2023) · Exploration of neuroscience · doi:10.37349/en.2023.00029 · Cited by 14
The neurobiological effects of senescence on dopaminergic system: A comprehensive review
Rocha, G. S., Freire, M. A. M., de Paiva, K. M., Oliveira, R. F., Morais, P. L. A. D. G., dos Santos, J. R., & Cavalcanti, J. R. L. D. P. (2024) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2024.102415 · Cited by 14
Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
Matera, C., Calvé, P., Casadó-Anguera, V., Sortino, R., Gomila, A. M. J., Moreno, E., Gener, T., Delgado-Sallent, C., Nebot, P., Costazza, D., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710114 · Cited by 14
Exposure to bright light biases effort-based decisions.
Bijleveld, E., & Knufinke, M. (2018) · Behavioral Neuroscience · doi:10.1037/bne0000244 · Cited by 15
Brooks, C., Kabiri, N. S., Mortazavi, F., Auerbach, S. H., Bonato, P., Erb, M. K., Czech, M., Karlin, D. R., Rolph, T., Bhangu, J. S., et al. (2020) · Chronobiology International · doi:10.1080/07420528.2020.1715998 · Cited by 12
Chen, J., Cho, K. E., Skwarzyńska, D., Clancy, S., Conley, N. J., Clinton, S. M., Li, X., Lin, L., & Zhu, J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1062-19.2020 · Cited by 13
Vitale, J. A., Briguglio, M., Galentino, R., Dell’Osso, B. M., Malgaroli, A., Banfi, G., & Porta, M. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.040 · Cited by 12
Pleasure: The missing link in the regulation of sleep
Rial, R. V., Cañellas, F., Gamundí, A., Akaârir, M., & Nicolau, M. C. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.03.012 · Cited by 13
Neurogenetics of Drosophila circadian clock: expect the unexpected
Jarabo, P., & Martín, F. A. (2017) · Journal of Neurogenetics · doi:10.1080/01677063.2017.1370466 · Cited by 11
Gaynes, B. I., Zaffer, A., Yousefzai, R., Chazaro-Cortes, M., Colletta, K., Kletzel, S., Jost, M. B., Park, Y., Chawla, J. P. S., Albert, M. V., et al. (2021) · Neurological Sciences · doi:10.1007/s10072-021-05245-8 · Cited by 11
Spiking and Membrane Properties of Rat Olfactory Bulb Dopamine Neurons
Korshunov, K. S., Blakemore, L. J., Bertram, R., & Trombley, P. Q. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00060 · Cited by 11
Self-citationExercise as a therapeutic strategy for insomnia: Current mechanisms and clinical relevance
Saadh, M. J., Saleh, A. Y., Kareem, R. A., Sharma, R. K., Roopashree, R., Sharma, G. C., Verma, R., Juneja, B., Sameer, H. N., Yaseen, A., et al. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.108681 · Cited by 14
Kirby, N. V., Tetzlaff, E. J., Kidd, S. A., Brown, E. E., Bezgrebelna, M., Yoon, L., Henderson, S. B., & Kenny, G. P. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179965 · Cited by 13
Role of Olfaction for Eating Behavior
Fadool, D. A., & Kolling, L. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.23770-x · Cited by 12
The impact of chronotype on circadian rest-activity rhythm and sleep characteristics across the week
Brooks, C., Kabiri, N. S., Bhangu, J. S., Cai, X., Pickering, E. H., Erb, M. K., Auerbach, S. H., Bonato, P., Moore, T. L., Mortazavi, F., et al. (2021) · Chronobiology International · doi:10.1080/07420528.2021.1937197 · Cited by 9
Cano-Cano, F., Martín-Loro, F., Gallardo-Orihuela, A., González-Montelongo, M. D. C., Ortuño‐Miquel, S., Hervás-Corpión, I., de la Villa, P., Ramón-Marco, L., Navarro-Calvo, J., Gómez-Jaramillo, L., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-54347-8 · Cited by 9
Light/dark phase-dependent spontaneous activity is maintained in dopamine-deficient mice
Fujita, M., Hagino, Y., Takeda, T., Kasai, S., Tanaka, M., Takamatsu, Y., Kobayashi, K., & Ikeda, K. (2017) · Molecular Brain · doi:10.1186/s13041-017-0329-4 · Cited by 9
Fagiani, F., Baronchelli, E., Pittaluga, A., Pedrini, E., Scacchi, C., Govoni, S. M., & Lanni, C. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.937174 · Cited by 10
Emerging preclinical interest concerning the role of circadian function in Parkinson’s disease
Willis, G. L., & Freelance, C. B. (2017) · Brain Research · doi:10.1016/j.brainres.2017.09.027 · Cited by 8
Chen, D., Qian, S., Qian, W., Wu, M., Wang, X., Shen, H., Long, X., Ye, M., Gong, Y., & Chen, G. (2024) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s465898 · Cited by 8
Day-Night Variations in the Concentration of Neurotransmitters in the Rat Lumbar Spinal Cord
Jiménez-Zárate, B. S., Piña-Leyva, C., Rodríguez-Sánchez, M., Florán, B., Jiménez-Zamudio, L. A., & Jiménez‐Estrada, I. (2021) · Journal of Circadian Rhythms · doi:10.5334/jcr.215 · Cited by 8
Sitnikova, E., Rutskova, E. M., Tsvetaeva, D. A., & Raevsky, V. V. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.06.003 · Cited by 8
Mesgar, S., Eskandari, K., Karimian-Sani-Varjovi, H., Salemi-Mokri-Boukani, P., & Haghparast, A. (2023) · Neurochemical Research · doi:10.1007/s11064-023-03988-8 · Cited by 8
Yang, X., Huang, G., Xu, M., Zhang, C., Cheng, Y., & Yang, Z. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193999 · Cited by 7
Kim, D., Kim, J., Kim, J.-S., Jeong, J.-K., Son, H.-S., Park, S., Jo, J., Ryu, S. M., Kim, E., Lee, S., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.594706 · Cited by 7
Badruzzaman, M., Goswami, C., & Sayed, M. A. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112941 · Cited by 6
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Tawa, E. A., & Notterman, D. A. (2025) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1581763 · Cited by 5
Holland, M. T., Mekhail, M. N., Thrash, G. W., George, T. P., Mugan, D., Paul, C. A., Shirvalkar, P. R., Grace, W. L., Deer, T. R., McGregor, K., et al. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106664 · Cited by 5
Zhang, A. Q., Ralph, M. R., & Stinchcombe, A. R. (2024) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1012082 · Cited by 5
Byun, J., Hyeon, J.-Y., Kim, E., Kim, S., Hur, S., Kim, S., & Takemura, A. (2019) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2019.110581 · Cited by 5
Rahmati‐Dehkordi, F., Ghaemi-Jandabi, M., Garmabi, B., Semnanian, S., & Azizi, H. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113450 · Cited by 4
Sekar, S., Zhang, Y., Miranzadeh Mahabadi, H., Buettner, B., & Taghibiglou, C. (2023) · doi:10.20944/preprints202305.0214.v1 · Cited by 11
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Reghunandanan, V. (2024) · Exploration of neuroscience · doi:10.37349/en.2024.00059 · Cited by 4
Weis, S., Sonnberger, M., Dunzinger, A., Voglmayr, E., Aichholzer, M., Kleiser, R., & Strasser, P. (2019) · Springer eBooks · doi:10.1007/978-3-7091-1544-2_13 · Cited by 4
Tran, K. K. N., Wong, V. H. Y., Vessey, K. A., Finkelstein, D. I., Bui, B. V., & Nguyen, C. T. O. (2024) · Biomedicines · doi:10.3390/biomedicines12010130 · Cited by 4
Oliveira, F. G., do Nascimento, E. S., Cavalcante, J. C., Gúzen, F. P., Cavalcante, J. S., Soares, J. G., Cavalcanti, J. R. L. D. P., de Freitas, L. M., Costa, M. S. M. D. O., & Andrade‐da‐Costa, B. L. D. S. (2017) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2017.12.007 · Cited by 4
Metadata
- Authors
- Korshunov, K. S., Blakemore, L. J., & Trombley, P. Q.
- Affiliations
- Florida State University (US)
- Corresponding author
- Trombley, Paul Q.
- Venue
- Frontiers in Cellular Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2017-04-03
- Volume
- 11
- Pages
- 91-91
- ISSN
- 1662-5102 (ISSN-L)
- PMC
- PMC5376559
- OpenAlex
- W2598018500
- Cited by
- 173
- References
- 173
- Citations by year
- 2026: 14 · 2025: 27 · 2024: 19 · 2023: 24 · 2022: 18 · 2021: 23 · 2020: 12 · 2019: 11 · 2018: 18 · 2017: 7
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Cellular Neuroscience (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (T32 DC000044)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- dopamine, circadian rhythm, clock genes, clock proteins, dopamine receptors, gap junctions, neuronal excitability, GABA, dopaminergic neurons, retina, olfactory bulb, striatum, midbrain, hypothalamus, Parkinson's disease, circadian rhythm disruption, light entrainment
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