Communication Impairment in Ultrasonic Vocal Repertoire during the Suckling Period of Cd157 Knockout Mice: Transient Improvement by Oxytocin
Open accessAbstract
Communication consists of social interaction, recognition, and information transmission. Communication ability is the most affected component in children with autism spectrum disorder (ASD). Recently, we reported that the CD157/BST1 gene is associated with ASD, and that CD157 knockout (Cd157−/−) mice display severe impairments in social behavior that are improved by oxytocin (OXT) treatment. Here, we sought to determine whether Cd157−/− mice can be used as a suitable model for communication deficits by measuring ultrasonic vocalizations (USVs), especially in the early developmental stage. Call number produced in pups due to isolation from dams was higher at postnatal day (PND) 3 in knockout pups than wild-type mice, but was lower at PNDs 7 and 10. Pups of both genotypes vocalized with a poorer voice repertoire at PND 3. However, although wild-type pups emitted USVs consisting of six different syllable types at PNDs 7 and 10, knockout pups vocalized with only two types. This developmental impairment in USV emission was rescued within 30 min by intraperitoneal OXT treatment, but quickly returned to control levels after 120 min, showing a transient effect of OXT. USV impairment was partially observed in Cd157+/- heterozygous mice, but not in Cd157−/− adult male mice examined while under courtship. These results demonstrate that CD157 gene deletion results in social communication insufficiencies, and suggests that CD157 is likely involved in acoustic communication. This unique OXT-sensitive developmental delay in Cd157−/− pups may be a useful model of communicative interaction impairment in ASD.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
CSF was collected according to the protocol for sampling CSF from mice without detectable plasma contamination.
“CSF was collected according to the protocol for sampling CSF from mice without detectable plasma contamination77,78.”
From Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice (2019) · cites this paper as [77]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The oxytocin receptor system: structure, function, and regulation
Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089 · see citing works
Satake, W., Nakabayashi, Y., Mizuta, I., Hirota, Y., Ito, C., Kubo, M., Kawaguchi, T., Tsunoda, T., Watanabe, M., Takeda, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.485 · Cited by 1,308 · see citing works
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
Takayanagi, Y., Yoshida, M., Bielsky, I. F., Ross, H. E., Kawamata, M., Onaka, T., Yanagisawa, T., Kimura, T., Matzuk, M. M., Young, L. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505312102 · Cited by 806 · see citing works
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
Yilmaz, Ö. H., Katajisto, P., Lamming, D. W., Gültekin, Y., Bauer-Rowe, K. E., Sengupta, S., Birsoy, K., Dursun, A., Yilmaz, V. O., Selig, M., et al. (2012) · Nature · doi:10.1038/nature11163 · Cited by 753 · see citing works
CD38 is critical for social behaviour by regulating oxytocin secretion
Jin, D., Liu, H.-X., Hirai, H., Torashima, T., Nagai, T., Lopatina, O., Shnayder, N. A., Yamada, K., Noda, M., Seike, T., et al. (2007) · Nature · doi:10.1038/nature05526 · Cited by 665 · see citing works
Self-citationUnusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism
Scattoni, M. L., Gandhy, S. U., Ricceri, L., & Crawley, J. N. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003067 · Cited by 550 · see citing works
Language acquisition in autism spectrum disorders: A developmental review
Eigsti, I., de Marchena, A. B., Schuh, J. M., & Kelley, E. A. (2010) · Research in Autism · doi:10.1016/j.rasd.2010.09.001 · Cited by 508 · see citing works
Scattoni, M. L., Crawley, J. N., & Ricceri, L. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.003 · Cited by 473 · see citing works
Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers
Lee, H. C. (2001) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.41.1.317 · Cited by 433 · see citing works
Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene
Shu, W., Cho, J. Y., Jiang, Y., Zhang, M., Weisz, D. J., Elder, G. A., Schmeidler, J., Gasperi, R. D., Sosa, M. A. G., Rabidou, D., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503739102 · Cited by 415 · see citing works
Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse
Winslow, J. T., Hearn, E. F., Ferguson, J., Young, L. J., Matzuk, M. M., & Insel, T. R. (2000) · Hormones and Behavior · doi:10.1006/hbeh.1999.1566 · Cited by 348 · see citing works
Yatawara, C. J., Einfeld, S. L., Hickie, I. B., Davenport, T. A., & Guastella, A. J. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.162 · Cited by 344 · see citing works
Central vasopressin and oxytocin release: regulation of complex social behaviours
VEENEMA, A., & NEUMANN, I. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00422-6 · Cited by 338 · see citing works
Branchi, I., Santucci, D., & Alleva, E. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00277-7 · Cited by 336 · see citing works
The social deficits of the oxytocin knockout mouse
Winslow, J. T., & Insel, T. R. (2002) · Neuropeptides · doi:10.1054/npep.2002.0909 · Cited by 307 · see citing works
Development of Social Vocalizations in Mice
Grimsley, J. M. S., Monaghan, J. J. M., & Wenstrup, J. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017460 · Cited by 291 · see citing works
Ultrasonic Communication in Rats: Can Playback of 50-kHz Calls Induce Approach Behavior?
Wöhr, M., & Schwarting, R. K. W. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001365 · Cited by 266 · see citing works
Social cognition and the evolution of language: constructing cognitive phylogenies
Fitch, W. T., Huber, L., & Bugnyar, T. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.011 · Cited by 264 · cited 1× · see citing works
“Language communication from an early life stage is an essential tool for bidirectional information transmission (Fitch et al., 2010; Kuhl, 2011), and is clearly delayed in certain ASD subtypes.”
BackgroundWu, T., Tzeng, Y., Chang, W.-W., Cheng, C., Kuo, Y., Chien, C.-H., Chang, H., & Yu, J. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.147 · Cited by 262 · see citing works
Ultraschall-Laute bei jungen M�usen
Zippelius, H., & Schleidt, W. M. (1956) · Die Naturwissenschaften · doi:10.1007/bf00632534 · Cited by 260 · see citing works
Graeff, R. M., Walseth, T. F., Fryxell, K., Branton, W. D., & Lee, H. C. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43806-9 · Cited by 243 · see citing works
Female mice respond to male ultrasonic ‘songs’ with approach behaviour
Hammerschmidt, K., Radyushkin, K., Ehrenreich, H., & Fischer, J. (2009) · Biology Letters · doi:10.1098/rsbl.2009.0317 · Cited by 226 · see citing works
Oxytocin Levels in Social Anxiety Disorder
Hoge, E. A., Pollack, M. H., Kaufman, R. E., Zak, P. J., & Simon, N. M. (2008) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2008.00051.x · Cited by 213 · see citing works
Lee, H. C. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.r112.349464 · Cited by 196 · see citing works
Central administration of oxytocin modulates the infant rats response to social isolation
Insel, T. R., & Winslow, J. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90806-2 · Cited by 185 · see citing works
BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.
Kaisho, T., Ishikawa, J., Oritani, K., Inazawa, J., Tomizawa, H., Muraoka, O., Ochi, T., & Hirano, T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5325 · Cited by 182 · see citing works
Genome-wide association study confirms extant PD risk loci among the Dutch
Simón‐Sánchez, J., van Hilten, J. J., van de Warrenburg, B. P. C., Post, B., Berendse, H. W., Arepalli, S., Hernandez, D. G., de Bie, R. M. A., Velseboer, D. C., Scheffer, H., et al. (2011) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.254 · Cited by 178 · see citing works
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls
Munesue, T., Yokoyama, S., Nakamura, K., Anitha, A., Yamada, K., Hayashi, K., Asaka, T., Liu, H.-X., Jin, D., Koizumi, K., et al. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.03.004 · Cited by 177 · see citing works
Self-citationEarly Language Learning and Literacy: Neuroscience Implications for Education
Kuhl, P. K. (2011) · Mind Brain and Education · doi:10.1111/j.1751-228x.2011.01121.x · Cited by 176 · see citing works
Guse, A. H. (2005) · The FEBS Journal · doi:10.1111/j.1742-4658.2005.04863.x · Cited by 139 · see citing works
Large-scale replication and heterogeneity in Parkinson disease genetic loci
Sharma, M., Ioannidis, J. P. A., Aasly, J. O., Annesi, G., Brice, A., Broeckhoven, C. V., Bertram, L., Bozi, M., Crosiers, D., Clarke, C. E., et al. (2012) · Neurology · doi:10.1212/wnl.0b013e318264e353 · Cited by 131 · see citing works
Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques
Freeman, S. M., Samineni, S., Allen, P. C., Stockinger, D., Bales, K. L., Hwa, G. G. C., & Roberts, J. A. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.01.014 · Cited by 128 · see citing works
Kosaka, H., Okamoto, Y., Munesue, T., Yamasue, H., Inohara, K., Fujioka, T., Anme, T., Orisaka, M., Ishitobi, M., Jung, M., et al. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.152 · Cited by 117 · see citing works
Self-citationEapen, V., Dadds, M. R., Barnett, B. E. W., Kohlhoff, J. R., Khan, F., Radom, N., & Silove, D. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107745 · Cited by 116 · see citing works
Shimaoka, Y., Attrep, J. F., Hirano, T., Ishihara, K., Suzuki, R., Toyosaki, T., Ochi, T., & Lipsky, P. E. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3162 · Cited by 109 · see citing works
Self-citationLopatina, O. L., Yoshihara, T., Nishimura, T., Zhong, J., Akther, S., Fakhrul, A. A. K. M., Liang, M., Higashida, C., Sumi, K., Furuhara, K., et al. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00133 · Cited by 106 · see citing works
Self-citationDisplays of paternal mouse pup retrieval following communicative interaction with maternal mates
Liu, H.-X., Lopatina, O., Higashida, C., Fujimoto, H., Akther, S., Ивановна, И. А., Liang, M., Zhong, J., Tsuji, T., Yoshihara, T., et al. (2013) · Nature Communications · doi:10.1038/ncomms2336 · Cited by 105 · see citing works
Self-citationMolecular Cloning of Murine BST-1 Having Homology with CD38 and Aplysia ADP-Ribosyl Cyclase
Itoh, M., Ishihara, K., Tomizawa, H., Tanaka, H., Kobune, Y., Ishikawa, J., Kaisho, T., & Hirano, T. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.2325 · Cited by 101 · see citing works
Self-citationShen, M. D., Li, D. D., Keown, C. L., Lee, A., Johnson, R. T., Angkustsiri, K., Rogers, S. J., Müller, R., Amaral, D. G., & Nordahl, C. W. (2016) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.05.020 · Cited by 98 · see citing works
Communication growth in minimally verbal children with ASD: The importance of interaction
DiStefano, C., Shih, W., Kaiser, A. P., Landa, R. J., & Kasari, C. L. (2016) · Autism Research · doi:10.1002/aur.1594 · Cited by 96 · see citing works
Leng, G., Pineda, R., Sabatier, N., & Ludwig, M. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0087 · Cited by 85 · see citing works
The many faces of oxytocin: Implications for psychiatry
Zik, J. B., & Roberts, D. L. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.11.048 · Cited by 85 · see citing works
Munesue, T., Nakamura, H., Kikuchi, M., Miura, Y., Takeuchi, N., Anme, T., Nanba, E., Adachi, K., Tsubouchi, K., Sai, Y., et al. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00002 · Cited by 84 · see citing works
Self-citationHusarova, V. M., Lakatošová, S., Pivovarciova, A., Babinská, K., Bakoš, J., Durdiaková, J., Kubranská, A., Ondrejka, I., & Ostatníková, D. (2016) · Psychiatry Investigation · doi:10.4306/pi.2016.13.2.174 · Cited by 78 · see citing works
Itoh, M., Ishihara, K., Hiroi, T., Lee, B. O., Maeda, H., Iijima, H., Yanagita, M., Kiyono, H., & Hirano, T. (1998) · Journal of Immunology · doi:10.4049/jimmunol.161.8.3974 · Cited by 71 · see citing works
Self-citationElevated plus-maze behavior in adult offspring of selectively bred rats
Dichter, G. S., Brunelli, S. A., & Hofer, M. A. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02222-8 · Cited by 66 · see citing works
CD157, the Janus of CD38 but with a unique personality
Ortolan, E., Vacca, P., Capobianco, A., Armando, E., Crivellin, F., Horenstein, A. L., & Malavasi, F. (2002) · Cell Biochemistry and Function · doi:10.1002/cbf.978 · Cited by 65 · see citing works
Reversal of social deficits by subchronic oxytocin in two autism mouse models
Teng, B. L., Nikolova, V. D., Riddick, N. V., Agster, K. L., Crowley, J. J., Baker, L. K., Koller, B. H., Pedersen, C. A., Jarstfer, M. B., & Moy, S. S. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.12.025 · Cited by 62 · see citing works
Experience restores innate female preference for male ultrasonic vocalizations
Shepard, K. N., & Liu, R. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00580.x · Cited by 61 · see citing works
Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling
Lee, H. C. (2011) · Science China Life Sciences · doi:10.1007/s11427-011-4197-3 · Cited by 60 · see citing works
Zhang, R., Jia, M., Zhang, J.-S., Xu, X., Shou, X., Zhang, X., Li, L., Li, N., Han, S., & Han, J. (2012) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2012.02.001 · Cited by 60 · see citing works
Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice
Liu, H.-X., Lopatina, O., Higashida, C., Tsuji, T., Kato, I., Takasawa, S., Okamoto, H., Yokoyama, S., & Higashida, H. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.09.084 · Cited by 58 · see citing works
An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator
Higashida, H., Liang, M., Yoshihara, T., Akther, S., Fakhrul, A. A. K. M., Михайлович, Ч. С., Nam, T., Kim, U., Kasai, S., Nishimura, T., et al. (2017) · BMC Neuroscience · doi:10.1186/s12868-017-0350-7 · Cited by 56 · see citing works
Self-citationMushtaq, M., Nam, T., & Kim, U. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.207100 · Cited by 53 · see citing works
Massey, S. H., Backes, K. A., & Schuette, S. (2016) · Depression and Anxiety · doi:10.1002/da.22467 · Cited by 53 · see citing works
Plasma oxytocin levels predict social cue recognition in individuals with schizophrenia
Strauss, G. P., Keller, W. R., Koenig, J. I., Gold, J. M., Frost, K. H., & Buchanan, R. W. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.01.034 · Cited by 51 · see citing works
Higashida, H. (2015) · The Journal of Physiological Sciences · doi:10.1007/s12576-015-0425-0 · Cited by 49 · see citing works
Self-citationCourtship ultrasonic vocalizations and social status in mice
D'Amato, F. R. (1991) · Animal Behaviour · doi:10.1016/s0003-3472(05)80354-9 · Cited by 45 · see citing works
Lopatina, O. L., Liu, H.-X., Amina, S., Hashii, M., & Higashida, H. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.012 · Cited by 45 · see citing works
Self-citationMychasiuk, R., & Rho, J. M. (2017) · Autism Research · doi:10.1002/aur.1682 · Cited by 45 · see citing works
Mizuno, A., Михайлович, Ч. С., Kikuchi, Y., Fakhrul, A. A. K. M., Akther, S., Deguchi, K., Yoshihara, T., Ishihara, K., Shuto, S., & Higashida, H. (2015) · Brain Sciences · doi:10.3390/brainsci5010003 · Cited by 43 · see citing works
Self-citationZhong, J., Amina, S., Liang, M., Akther, S., Yuhi, T., Nishimura, T., Tsuji, C., Tsuji, T., Liu, H.-X., Hashii, M., et al. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00304 · Cited by 42 · see citing works
Self-citationAnalysis of genome‐wide association study‐linked loci in Parkinson's disease of Mainland China
Liu, J., Xiao, Q., Wang, Y., et al. (2013) · Movement Disorders · doi:10.1002/mds.25599 · Cited by 38 · see citing works
CD38: A NAADP degrading enzyme
Schmid, F., Bruhn, S., Weber, K., Mittrücker, H., & Guse, A. H. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.10.017 · Cited by 38 · see citing works
Salmina, A. B., Lopatina, O., Ekimova, M. V., Mikhutkina, S. V., & Higashida, H. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01970.x · Cited by 36 · see citing works
Self-citationCeroni, F., Sagar, A., Simpson, N. H., Gawthrope, A. J. T., Newbury, D. F., Pinto, D., Francis, S. M., Tessman, D. C., Cook, E. H., Monaco, A. P., et al. (2014) · Autism Research · doi:10.1002/aur.1365 · Cited by 34 · see citing works
Association Study between the CD157/BST1 Gene and Autism Spectrum Disorders in a Japanese Population
Yokoyama, S., Mahmuda, N. A., Munesue, T., Hayashi, K., Yagi, K., Yamagishi, M., & Higashida, H. (2015) · Brain Sciences · doi:10.3390/brainsci5020188 · Cited by 29 · see citing works
Self-citationAmina, S., Hashii, M., Ma, W. ‐., Yokoyama, S., Lopatina, O. L., Liu, H., Islam, M. S., & Higashida, H. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01978.x · Cited by 27 · see citing works
Self-citationAlthaus, M., Groen, Y., Wijers, A. A., Noltes, H., Tucha, O. M., Sweep, F. C. G. J., Calcagnoli, F., & Hoekstra, P. J. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4339-1 · Cited by 27 · see citing works
Effects of oxytocin on serotonin 1B agonist-induced autism-like behavior in mice
Lawson, S. K., Gray, A. C., & Woehrle, N. S. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.07.027 · Cited by 25 · see citing works
Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder
Wei, H., Ma, Y., Ding, C., Jin, G., Liu, J., Chang, Q., Hu, F., & Li, Y. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2035-5 · Cited by 22 · see citing works
Ultrasonic vocalizations during male–female interaction in the mouse model of Down syndrome Ts65Dn
Zampieri, B. L., Fernandez, F., Pearson-Smith, J. N., Stasko, M. R., & Costa, A. C. S. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.02.020 · Cited by 21 · see citing works
Zhu, L.-H., Luo, X., Zhou, Y., et al. (2012) · PubMed · Cited by 17 · see citing works
CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion
Buono, N. L. (2014) · Frontiers in bioscience · doi:10.2741/4213 · Cited by 16 · see citing works
Zheng, Z., Warren, Z. E., Weitlauf, A. S., Fu, Q., Zhao, H., Swanson, A. R., & Sarkar, N. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2896-0 · Cited by 9 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Franklin K. B. J. Paxinos G. (2008). The Mouse Brain in Stereotaxic Coordinates, 3rd Edn. Amsterdam: Elsevier, AP.
Cited by
Sorted by citations
Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice
Yamamoto, Y., Liang, M., Munesue, S., Deguchi, K., Harashima, A., Furuhara, K., Yuhi, T., Zhong, J., Akther, S., Goto, H., et al. (2019) · Communications Biology · doi:10.1038/s42003-019-0325-6 · Cited by 171 · see citing works
Self-citationCD38, CD157, and RAGE as Molecular Determinants for Social Behavior
Higashida, H., Hashii, M., Tanaka, Y., Matsukawa, S., Higuchi, Y., Gabata, R., Tsubomoto, M., Seishima, N., Teramachi, M., Kamijima, T., et al. (2019) · Cells · doi:10.3390/cells9010062 · Cited by 58 · see citing works
Self-citation
- Authors
- Lopatina, O. L., Furuhara, K., Ishihara, K., Salmina, A. B., & Higashida, H.
- Affiliations
- Kanazawa University (JP)
- Kawasaki Medical School (JP)
- Krasnoyarsk State Medical University (RU)
- Corresponding author
- Lopatina, Olga L.
- Venue
- Frontiers in Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2017-05-17
- Volume
- 11
- Issue
- MAY
- Pages
- 266-266
- ISSN
- 1662-453X (ISSN-L)
- PMC
- PMC5434149
- OpenAlex
- W2615792099
- Cited by
- 30
- References
- 75
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 2 · 2022: 2 · 2021: 8 · 2020: 7 · 2019: 5 · 2018: 2 · 2017: 1
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Neuroscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Institutional Repositories DataBase (IRDB) (submittedVersion)
- Kanazawa University Repository for Academic Resources (DSpace) (Kanazawa University) (submittedVersion, cc-by-nc-nd)
- Funders
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science and Technology
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- oxytocin, ultrasonic vocalizations, social communication, autism spectrum disorder, suckling period, acoustic communication, social behavior, developmental delay, heterozygous mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
