Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice
Abstract
Oxytocin (OT), a neurohormone involved in reproduction, plays a critical role in social behavior in a wide range of mammalian species from rodents to humans. The role of CD38 in regulating OT secretion for social behavior has been demonstrated in adult mice, but has not been examined in pups or during development. Separation from the dam induces stress in 7-day-old mouse pups. During such isolation, locomotor activity was higher in CD38 knockout (CD38(-/-)) pups than in wild-type (CD38(+/+)) or heterozygous (CD38(+/-)) controls. The number of ultrasonic vocalizations was lower in CD38(-/-) pups than in CD38(+/+) pups. However, the difference between the two genotypes was less severe than that in OT knockout or OT receptor knockout mice. To explain this, we measured plasma OT levels. The level was not lower in CD38(-/-) pups during the period 1-3 weeks after birth, but was significantly reduced after weaning (>3 weeks). ADP-ribosyl cyclase activities in the hypothalamus and pituitary were markedly lower from 1 week after birth in CD38(-/-) mice and were consistently lower thereafter to the adult stage (2 months old). These results showed that the reduced severity of behavioral abnormalities in CD38(-/-) pups was due to partial compensation by the high level of plasma OT.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
CD38 -/- pups emit fewer ultrasonic vocalization calls (average reduction of 38%) than wild-type controls.
“The USV calls per 2-min session were less frequent (an average reduction of 38%) in CD38 -/-pups than in wild-type controls (Liu et al., 2008).”
From CD38 and its role in oxytocin secretion and social behavior (2012) · cites this paper as Liu et al., 2008
CD38 -/- male pups on postnatal day 7 have significantly higher locomotor activity than wild-type during the first 3 min after separation from the dam.
“CD38 -/-male pups on postnatal day 7 had significantly higher levels of locomotor activity, compared to wild-type individuals, during the first 3 min after separation from the dam when they were examined individually in a grid-crossing test performed in an observation chamber (Liu et al., 2008).”
From CD38 and its role in oxytocin secretion and social behavior (2012) · cites this paper as Liu et al., 2008
CD38 may have an important role in OT release in the human hypothalamus, as in mice.
“These results suggested that CD38 may have an important role in OT release in the human hypothalamus, as in the mice (Jin et al., 2007;Liu et al., 2008).”
From Two genetic variants of CD38 in subjects with autism spectrum disorder and controls (2010) · cites this paper as Liu et al., 2008
CD38 regulates OT secretion in the mouse hypothalamus and posterior pituitary, which is critical for mouse social behavior.
“They showed that CD38 regulates OT secretion in the mouse hypothalamus and posterior pituitary, which is critical for mouse social behavior (Jin et al., 2007;Liu et al., 2008).”
From Two genetic variants of CD38 in subjects with autism spectrum disorder and controls (2010) · cites this paper as Liu et al., 2008
Cites
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
The neurobiology of pair bonding.
Young, L. J., & Wang, Z. (2004) · Nature Neuroscience · doi:10.1038/nn1327 · Cited by 1,523 · cited 1× · see citing works
“In rodents, OT is highly involved in social interaction, social recognition, pair bonding, and maternal behavior [8,15,17,18,19,22,25,30].”
Social amnesia in mice lacking the oxytocin gene
Ferguson, J. N., Young, L. J., Hearn, E. F., Matzuk, M. M., Insel, T. R., & Winslow, J. T. (2000) · Nature Genetics · doi:10.1038/77040 · Cited by 1,130 · see citing works
Oxytocin in the Medial Amygdala is Essential for Social Recognition in the Mouse
Ferguson, J. N., Aldag, J. M., Insel, T. R., & Young, L. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08278.2001 · Cited by 1,043 · see citing works
Oxytocin increases generosity in humans
Zak, P. J., Stanton, A. A., & Ahmadi, S. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001128 · Cited by 831 · see citing works
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
Takayanagi, Y., Yoshida, M., Bielsky, I. F., Ross, H. E., Kawamata, M., Onaka, T., Yanagisawa, T., Kimura, T., Matzuk, M. M., Young, L. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505312102 · Cited by 806 · see citing works
Plasma oxytocin levels in autistic children
Modahl, C., Green, L. A., Fein, D., Morris, M., Waterhouse, L., Feinstein, C., & Levin, H. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00439-3 · Cited by 728 · see citing works
Oxytocin Infusion Reduces Repetitive Behaviors in Adults with Autistic and Asperger's Disorders
Hollander, E., Novotny, S., Hanratty, M., Yaffe, R., DeCaria, C. M., Aronowitz, B. R., & Mosovich, S. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300021 · Cited by 689 · see citing works
CD38 is critical for social behaviour by regulating oxytocin secretion
Jin, D., Liu, H.-X., Hirai, H., Torashima, T., Nagai, T., Lopatina, O., Shnayder, N. A., Yamada, K., Noda, M., Seike, T., et al. (2007) · Nature · doi:10.1038/nature05526 · Cited by 665 · see citing works
Self-citationNeuropeptidergic regulation of affiliative behavior and social bonding in animals
Lim, M. M., & Young, L. J. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.06.028 · Cited by 624 · see citing works
Fries, A. B. W., Ziegler, T. E., Kurian, J. R., Jacoris, S., & Pollak, S. D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504767102 · Cited by 570 · see citing works
HOW THE BRAIN PROCESSES SOCIAL INFORMATION: Searching for the Social Brain
Insel, T. R., & Fernald, R. D. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144148 · Cited by 556 · see citing works
Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene
Shu, W., Cho, J. Y., Jiang, Y., Zhang, M., Weisz, D. J., Elder, G. A., Schmeidler, J., Gasperi, R. D., Sosa, M. A. G., Rabidou, D., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503739102 · Cited by 415 · see citing works
The expectant brain: adapting for motherhood
Brunton, P. J., & Russell, J. A. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2280 · Cited by 407 · see citing works
Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse
Winslow, J. T., Hearn, E. F., Ferguson, J., Young, L. J., Matzuk, M. M., & Insel, T. R. (2000) · Hormones and Behavior · doi:10.1006/hbeh.1999.1566 · Cited by 348 · see citing works
Vasopressin, oxytocin and social behaviour
Keverne, E. B., & Curley, J. P. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.10.006 · Cited by 215 · see citing works
Low doses of oxytocin facilitate social recognition in rats
Popik, P., Vetulani, J., & van Ree, J. M. (1992) · Psychopharmacology · doi:10.1007/bf02253591 · Cited by 212 · see citing works
Dynamic changes in oxytocin receptor expression and activation at parturition in the rat brain
Meddle, S. L., Bishop, V. R., Gkoumassi, E., van Leeuwen, F. W., & Douglas, A. J. (2007) · Endocrinology · doi:10.1210/en.2007-0615 · Cited by 195 · see citing works
Maternal behavior deficits in nulliparous oxytocin knockout mice
Pedersen, C. A., Vadlamudi, S. V., Boccia, M. L., & Amico, J. A. (2006) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2005.00162.x · Cited by 190 · see citing works
Huddling by rat pups: Multisensory control of contact behavior.
Alberts, J. R. (1978) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077458 · Cited by 157 · see citing works
Huddling by rat pups: Ontogeny of individual and group behavior
Alberts, J. R. (2007) · Developmental Psychobiology · doi:10.1002/dev.20190 · Cited by 115 · see citing works
Human placental transport of oxytocin
Malek, A., Blann, E., & Mattison, D. R. (1996) · The Journal of Maternal-Fetal Medicine · doi:10.1002/(sici)1520-6661(199609/10)5:5 · Cited by 114 · see citing works
Sympathetic Potentiation of Cyclic ADP-ribose Formation in Rat Cardiac Myocytes
Higashida, H., Egorova, A., Higashida, C., Zhong, Z., Yokoyama, S., Noda, M., & Zhang, J.-S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.47.33348 · Cited by 88 · see citing works
Developmental effects of oxytocin on stress response: Single versus repeated exposure
KRAMER, K., CUSHING, B., & CARTER, C. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00175-6 · Cited by 79 · see citing works
CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain
Ceni, C., Pochon, N., Brun, V., Muller‐Steffner, H., Andrieux, A., Grünwald, D., Schuber, F. J., WAARD, M. M. D., Lund, F. E., Villaz, M., et al. (2003) · Biochemical Journal · doi:10.1042/bj20020604 · Cited by 66 · see citing works
Weaning time of children with infantile autism
Tanoue, Y., & Oda, S. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212940 · Cited by 64 · see citing works
Rabbit Whey Acidic Protein Concentration in Milk, Serum, Mammary Gland Extract, and Culture Medium
Grabowski, H., Bars, D. L., Chene, N., Attal, J., Malienou-Ngassa, R., Puissant, C., & Houdebine, L. (1991) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(91)78609-8 · Cited by 52 · see citing works
Ceni, C., Pochon, N., Villaz, M., Muller‐Steffner, H., Schuber, F. J., Baratier, J., WAARD, M. M. D., Ronjat, M., & Moutin, M. (2006) · Biochemical Journal · doi:10.1042/bj20051321 · Cited by 36 · see citing works
Maternal behavior: activation of the central oxytocin receptor system in parturient rats?
Lin, S. H., Kiyohara, T., & Sun, B. (2003) · Neuroreport · doi:10.1097/00001756-200308060-00007 · Cited by 25 · see citing works
Reis, B. L., Keen, C. L., Lönnerdal, B. L., & Hurley, L. S. (1991) · Journal of Nutrition · doi:10.1093/jn/121.5.687 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Social vocalizations can release oxytocin in humans
Seltzer, L. J., Ziegler, T. E., & Pollak, S. D. (2010) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2010.0567 · Cited by 298 · see citing works
Naviaux, J. C., Wang, L., Li, K., Bright, A., Alaynick, W. A., Williams, K. R., Powell, S. B., & Naviaux, R. K. (2015) · Molecular Autism · doi:10.1186/2040-2392-6-1 · Cited by 285 · see citing works
Feldman, R. (2015) · Development and Psychopathology · doi:10.1017/s0954579415000048 · Cited by 271 · see citing works
The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies
Modi, M. E., & Young, L. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.010 · Cited by 218 · see citing works
Developmental Perspectives on Oxytocin and Vasopressin
Hammock, E. A. D. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.120 · Cited by 177 · see citing works
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls
Munesue, T., Yokoyama, S., Nakamura, K., Anitha, A., Yamada, K., Hayashi, K., Asaka, T., Liu, H.-X., Jin, D., Koizumi, K., et al. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.03.004 · Cited by 177 · see citing works
Interplay between Oxytocin and Sensory Systems in the Orchestration of Socio-Emotional Behaviors
Grinevich, V., & Stoop, R. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.016 · Cited by 139 · see citing works
Lukas, M., & Neumann, I. D. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.08.011 · Cited by 136 · see citing works
Autism and Oxytocin: New Developments in Translational Approaches to Therapeutics
Green, J. J., & Hollander, E. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.006 · Cited by 124 · see citing works
Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders
Grinevich, V., Desarménien, M. G., Chini, B., Tauber, M., & Muscatelli, F. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00164 · Cited by 121 · see citing works
Bertoni, A., Schaller, F., Tyzio, R., Gaillard, S., Santini, F., Xolin, M., Diabira, D., Vaidyanathan, R., Matarazzo, V. A., Medina, I., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01227-6 · Cited by 110 · see citing works
CD38 and its role in oxytocin secretion and social behavior
Higashida, H., Yokoyama, S., Kikuchi, M., & Munesue, T. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.011 · Cited by 98 · see citing works
Higashida, H., Lopatina, O., Yoshihara, T., Pichugina, Y. A., Soumarokov, A. A., Munesue, T., Minabe, Y., Kikuchi, M., Ono, Y., Korshunova, N., et al. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01976.x · Cited by 98 · see citing works
Husarova, V. M., Lakatošová, S., Pivovarciova, A., Babinská, K., Bakoš, J., Durdiaková, J., Kubranská, A., Ondrejka, I., & Ostatníková, D. (2016) · Psychiatry Investigation · doi:10.4306/pi.2016.13.2.174 · Cited by 78 · see citing works
Oxytocin, sexually dimorphic features of the social brain, and autism
Yamasue, H., Kuwabara, H., Kawakubo, Y., & Kasai, K. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01944.x · Cited by 78 · see citing works
Zhang, R., Zhang, H.-F., Han, J., & Han, S. (2017) · Neuroscience Bulletin · doi:10.1007/s12264-017-0120-7 · Cited by 78 · see citing works
Higashida, H., Yokoyama, S., Huang, J., Liu, L., Ma, W., Akther, S., Higashida, C., Kikuchi, M., Minabe, Y., & Munesue, T. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.01.030 · Cited by 74 · see citing works
The Roles of Oxytocin and CD38 in Social or Parental Behaviors
Lopatina, O. L., Ивановна, И. А., Salmina, A. B., & Higashida, H. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00182 · Cited by 64 · see citing works
Cd38 Gene Knockout Juvenile Mice: A Model of Oxytocin Signal Defects in Autism
Higashida, H., Yokoyama, S., Munesue, T., Kikuchi, M., Minabe, Y., & Lopatina, O. L. (2011) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.34.1369 · Cited by 63 · see citing works
Oxytocin and excitation/inhibition balance in social recognition
Lopatina, O. L., Komleva, Y. K., Gorina, Y. V., Olovyannikova, R. Y., Труфанова, Л. В., Hashimoto, T., Takahashi, T., Kikuchi, M., Minabe, Y., Higashida, H., et al. (2018) · Neuropeptides · doi:10.1016/j.npep.2018.09.003 · Cited by 51 · see citing works
Higashida, H., Furuhara, K., Yamauchi, A.-M., Deguchi, K., Harashima, A., Munesue, S., Lopatina, O. L., Gerasimenko, M., Salmina, A. B., Zhang, J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07949-4 · Cited by 46 · see citing works
Muscatelli, F., Desarménien, M. G., Matarazzo, V. A., & Grinevich, V. (2017) · Current topics in behavioral neurosciences · doi:10.1007/7854_2017_16 · Cited by 46 · see citing works
Lopatina, O. L., Liu, H.-X., Amina, S., Hashii, M., & Higashida, H. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.012 · Cited by 45 · see citing works
Lopatina, O. L., Ивановна, И. А., Пичугина, Ю. А., Okamoto, H., Salmina, A. B., & Higashida, H. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02136.x · Cited by 47 · see citing works
Pre- and Postnatal Exposure to Low Dose Glufosinate Ammonium Induces Autism-Like Phenotypes in Mice
Laugeray, A., Herzine, A., Perche, O., Hébert, B., Aguillon-Naury, M., Richard, O., Menuet, A., Mazaud‐Guittot, S., Lesné, L., Briault, S., et al. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00390 · Cited by 41 · see citing works
Ma, W.-J., Hashii, M., Munesue, T., Hayashi, K., Yagi, K., Yamagishi, M., Higashida, H., & Yokoyama, S. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-22 · Cited by 42 · see citing works
Tsuji, T., Miyoshi, T., Higashida, C., Narumiya, S., & Watanabe, N. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004921 · Cited by 38 · see citing works
Oxytocin Signaling Pathway: From Cell Biology to Clinical Implications
Iovino, M., Messana, T., Tortora, A., Giusti, C., Lisco, G., Giagulli, V. A., Guastamacchia, E., Pergola, G. D., & Triggiani, V. (2020) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530320666200520093730 · Cited by 39 · see citing works
Salmina, A. B., Lopatina, O., Ekimova, M. V., Mikhutkina, S. V., & Higashida, H. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01970.x · Cited by 36 · see citing works
New directions in the treatment of autism spectrum disorders from animal model research
Chadman, K. K., Guariglia, S. R., & Yoo, J. H. (2012) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2012.678828 · Cited by 32 · see citing works
Lopatina, O. L., Furuhara, K., Ishihara, K., Salmina, A. B., & Higashida, H. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00266 · Cited by 30 · see citing works
A multiscale analysis in CD38 −/− mice unveils major prefrontal cortex dysfunctions
Martucci, L. L., Amar, M., Chaussenot, R., Benet, G., Bauer, O., de Zélicourt, A., Nosjean, A., Launay, J., Callebert, J., Sebrié, C., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201800489r · Cited by 29 · see citing works
Pairmate-dependent pup retrieval as parental behavior in male mice
Liang, M., Zhong, J., Liu, H.-X., Lopatina, O., Nakada, R., Yamauchi, A.-M., & Higashida, H. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00186 · Cited by 25 · see citing works
Liu, J., Gong, P., Li, H., & Zhou, X. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.08.010 · Cited by 24 · see citing works
Effects of Three Lipidated Oxytocin Analogs on Behavioral Deficits in CD38 Knockout Mice
Михайлович, Ч. С., Akther, S., Nishimura, T., Shabalova, A. A., Mizuno, A., Ichinose, W., Shuto, S., Yamamoto, Y., Yokoyama, S., & Higashida, H. (2017) · Brain Sciences · doi:10.3390/brainsci7100132 · Cited by 23 · see citing works
Gerasimenko, M., Lopatina, O. L., Shabalova, A. A., Михайлович, Ч. С., Salmina, A. B., Yokoyama, S., Goto, H., Okamoto, H., Yamamoto, Y., Ishihara, K., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0244022 · Cited by 19 · see citing works
Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion
Martucci, L. L., Launay, J., Kawakami, N., Sicard, C., Samson-Desvignes, N., Dakouane‐Giudicelli, M., Spix, B., Têtu, M., Gilmaire, F.-O., Paulcan, S., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2213682120 · Cited by 20 · see citing works
Neonatal oxytocin gives the tempo of social and feeding behaviors
Muscatelli, F., Matarazzo, V. A., & Chini, B. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1071719 · Cited by 17 · see citing works
Spanos, M., Chandrasekhar, T., Kim, S., Hamer, R. M., King, B. H., McDougle, C. J., Sanders, K. B., Gregory, S. G., Kolevzon, A. L., Veenstra-VanderWeele, J. M., et al. (2020) · Contemporary Clinical Trials · doi:10.1016/j.cct.2020.106103 · Cited by 22 · see citing works
The Role of the Oxytocin/Arginine Vasopressin System in Animal Models of Autism Spectrum Disorder
Zhang, R., Xu, X., Zhang, H.-F., Han, S., & Han, J. (2017) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-52498-6_8 · Cited by 16 · see citing works
Rybicka, M., Kaźmierczak, M., Pawlicka, P., Łada‐Maśko, A., Anikiej‐Wiczenbach, P., & Bielawski, K. P. (2021) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2021.105294 · Cited by 10 · see citing works
Neuroendocrinology and Behavior
Sumiyoshi, T. (2012) · InTech eBooks · doi:10.5772/1666 · Cited by 9 · see citing works
Khani, P., Dezfouli, M. A., Nasri, F., Rahemi, M., Ahmadloo, S., Afkhami, H., Saeidi, F., Tereshchenko, S. Y., Bigdeli, M. R., & Modarressi, M. H. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1002048 · Cited by 5 · see citing works
Lee, M. R., Shin, J. H., Deschaine, S. L., Daurio, A. M., Stangl, B. L., Yan, J., Ramchandani, V. A., Schwandt, M. L., Grodin, E. N., Momenan, R., et al. (2019) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2019.1638928 · Cited by 5 · see citing works
Tereshchenko, S. Y., Каспаров, Э. В., Николаевна, З. С., Smolnikova, M. V., Evert, L. S., Zaitseva, O., Зайцева, О. И., Nina, G., Lapteva, L., & Semenova, N. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.714093 · Cited by 3 · see citing works
Serotonin Disturbance in Mouse Models of Autism Spectrum Disorders
Tamada, K., & Takumi, T. (2014) · Neuromethods · doi:10.1007/978-1-4939-2250-5_9 · Cited by 4 · see citing works
Neural Targets in the Study and Treatment of Social Cognition in Autism Spectrum Disorder
Vahabzadeh, A. B. N., Landino, S. M., Finger, B. C., Carlezon, W. A., & McDougle, C. J. (2015) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-16522-6_11 · Cited by 3 · see citing works
Munesue, T., 芦村, 和., Nakatani, H., Kikuchi, M., Yokoyama, S., Oi, M., Higashida, H., & Minabe, Y. (2012) · InTech eBooks · doi:10.5772/48798 · Cited by 2 · see citing works
Serum Oxytocin Level Among Male Patients With Opioid Dependence and Its Relation to Craving
Mobasher, M. W., Fathy, H., Soliman, A., El-Hanafi, H., & El-Makawi, S. M. (2020) · Addictive Disorders & Their Treatment · doi:10.1097/adt.0000000000000231 · Cited by 2 · see citing works
L’ocytocine, dès la naissance, conditionne le comportement alimentaire et social d’un individu
Muscatelli, F. (2022) · Biologie Aujourd hui · doi:10.1051/jbio/2022017 · Cited by 2 · see citing works
El-Makawi, S. M., Mobasher, M. W., Eid, H., Soliman, A., El-Hanafi, H., Adel, S., & Mahfouz, N. A. (2021) · Egyptian Journal of Psychiatry · doi:10.4103/ejpsy.ejpsy_44_20 · Cited by 2 · see citing works
Regulation of oxytocin and vasopressin secretion
Higashida, H., Lopatina, O. L., & Amina, S. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.005 · Cited by 1 · see citing works
Discovery, Development, and Mechanisms of Action of the Human CD38 Antibody Daratumumab
Janmaat, M. L., van de Donk, N. W. C. J., van Bueren, J. J. L., Ahmadi, T., Sasser, A. K., Jansson, R. K., Lokhorst, H. M., & Parren, P. W. H. I. (2018) · Wiley eBooks · doi:10.1002/9783527808694.ch7 · Cited by 1 · see citing works
Oxytocin genetic pathway (CD38) and SDQ psychosocial characteristics in adolescent schoolchildren
Tereshchenko, S. Y., Azanova, A. V., Валерьевна, Ш. М., & Gorbacheva, N. (2022) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro2022122111117
Bertoni, A. (2019) · theses.fr (ABES) · doi:10.70675/d43fcf44zc66ez47a1zae43zd20439e2b233
New regulators in oxytocin and vasopressin release : role of the endolysosomal two-pore channels
Martucci, L. L. (2021) · theses.fr (ABES) · doi:10.70675/027d1ae2zd2ebz4677za019ze6ccd94cafe9
Schaller, F., Alifrangis, M.-S., Barelle, P.-Y., Santos, C., Tyzio, R., Bertoni, A., Omnes, F., Belaïdouni, Y., Bader, F., Pallesi‐Pocachard, E., et al. (2026) · Molecular Autism · doi:10.1186/s13229-026-00744-x
- Authors
- Liu, H.-X., Lopatina, O., Higashida, C., Tsuji, T., Kato, I., Takasawa, S., Okamoto, H., Yokoyama, S., & Higashida, H.
- Affiliations
- Kanazawa University (JP)
- University of Toyama (JP)
- Nara Medical University (JP)
- Tohoku University (JP)
- Corresponding author
- Higashida, Haruhiro
- ORCID
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 448
- Issue
- 1
- Pages
- 67-70
- ISSN
- 0304-3940 (ISSN-L)
- OpenAlex
- W1984220337
- Cited by
- 58
- References
- 30
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 4 · 2019: 3 · 2018: 3 · 2017: 7 · 2016: 1 · 2015: 4 · 2014: 4 · 2013: 3 · 2012: 5
- FWCI
- 5.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Letters (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Keywords
- CD38, oxytocin, CD38 knockout mice, neonatal mice, locomotor activity, ultrasonic vocalizations, social behavior, maternal separation, ADP-ribosyl cyclase, hypothalamus, pituitary gland, plasma oxytocin, weaning, brain development
- MeSH terms
- Age Factors, Animals, Animals, Newborn, Female, Hypothalamus, Male, Motor Activity, Oxytocin, Pituitary Gland, Posterior, Social Isolation, Vocalization, Animal, Mice, Knockout, ADP-ribosyl Cyclase, Mice, ADP-ribosyl Cyclase 1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
