NLRP3 inflammasome and its inhibitors: a review

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5. USP1 Inhibits NF-κB/NLRP3 Induced Pyroptosis through TRAF6 in Osteoblastic MC3T3-E1 Cells.
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7. Targeted-Neuroinflammation Mitigation Using Inflammasome-Inhibiting Nanoligomers is Therapeutic in an Experimental Autoimmune Encephalomyelitis Mouse Model
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9. Therapeutic role of NLRP3 inflammasome inhibitors against Alzheimer’s disease
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10. The XPO1 Inhibitor KPT-8602 Ameliorates Parkinson’s Disease by Inhibiting the NF-κB/NLRP3 Pathway
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11. Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children
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12. Black Carbon Induces Cytotoxicity and NLRP3 Inflammasome Activation in Human Corneal Epithelial Cells
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17. TRIM59 suppresses the brain ischaemia/reperfusion injury and pyroptosis of microglial through mediating the ubiquitination of NLRP3
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18. Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3
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19. Tranilast alleviates visceral hypersensitivity and colonic hyperpermeability by suppressing NLRP3 inflammasome activation in irritable bowel syndrome rat models
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20. MCC950 promotes diabetic wound healing through modulating macrophage polarization in an MDSC-dependent manner
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21. Opportunities and Challenges for Nanomaterials as Vaccine Adjuvants
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22. Mechanistic insights curcumin’s anti-inflammatory in pancreatic cancer: experimental and computational evidence implicating IL1B interference via IL10RA upregulation and NLRP3/TLR3 downregulation
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23. Chronic unpredictable mild stress accelerates lipopolysaccharide- induced microglia activation and damage of dopaminergic neurons in rats
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24. Manganese induces neuroinflammation via NF-κB/ROS NLRP3 pathway in rat brain striatum and HAPI cells
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25. Local intra-articular injection of rapamycin inhibits NLRP3 activity and prevents osteoarthritis in mouse DMM models
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26. Association of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 polymorphisms with systemic lupus erythematosus disease activity and biomarker levels
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27. Overexpression of TRIM3 protects against LPS-induced acute kidney injury via repressing IRF3 pathway and NLRP3 inflammasome
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28. New insights into the regulatory roles of glutathione in NLRP3-inflammasome-mediated immune and inflammatory responses
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29. Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway
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31. A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner
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32. LncRNA MEG3 promotes pyroptosis via miR-145-5p/TLR4/NLRP3 axis and aggravates cerebral ischemia-reperfusion injury
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33. Narirutin mitigates inflammatory arthritis and osteoporosis through modulating macrophage phenotype and osteoclastogenesis
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34. Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis
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35. Sporoderm-removed Ganoderma lucidum spores ameliorated early depression-like behavior in a rat model of sporadic Alzheimer’s disease
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36. The Potential Impact of SGLT2-I in Diabetic Foot Prevention: Promising Pathophysiologic Implications, State of the Art, and Future Perspectives—A Narrative Review
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37. The role of NLRP3 inflammasome-mediated pyroptosis in astrocytes during hyperoxia-induced brain injury
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38. C1q/tumor necrosis factor‐related protein 9 protects cultured chondrocytes from IL ‐1β‐induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1 / AMPK axis
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39. Inhibition of the P2X7/NLRP3 Inflammasome Signaling Pathway by Deacetylgedunin from Toona sinensis
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40. Annexin A1 inhibition facilitates NLRP3 inflammasome activation in arsenic-induced insulin resistance in rat liver
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41. Effects of a pathogenic ETEC strain and a probiotic Enterococcus faecium strain on the inflammasome response in porcine dendritic cells
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42. Mechanism of activation of TLR4/NF-κB/NLRP3 signaling pathway induced by heat stress disrupting the filtration barrier in broiler
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44. Mitophagy–NLRP3 Inflammasome Crosstalk in Parkinson’s Disease: Pathogenic Mechanisms and Emerging Therapeutic Strategies
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50. A comprehensive review on rhubarb astringent/ laxative actions and the role of aquaporins as hub genes
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52. Teneligliptin mitigates diabetic cardiomyopathy by inhibiting activation of the NLRP3 inflammasome
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53. Celastrol specifically inhibits the activation of NLRP3 inflammasome
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54. Compromised NLRP 3 and AIM 2 inflammasome function in autoimmune NZB /W F1 mouse macrophages
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55. Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
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56. α‐Mangostin protects lipopolysaccharide‐stimulated nucleus pulposus cells against NLRP3 inflammasome‐mediated apoptosis via the NF‐κB pathway
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57. Vitamin C inhibits apoptosis in THP‑1 cells in response to incubation with Mycobacterium tuberculosis
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58. Application of induced pluripotent stem cells to primary immunodeficiency diseases
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62. MCC950 attenuates plasma cell mastitis in an MDSC-dependent manner
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63. Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation
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70. Morbus Still im Kindes- und Erwachsenenalter
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83. Clinical application of serum NLRP3 on the diagnosis and prognosis of sepsis patients complicated with acute respiratory distress syndrome
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84. Role of NLRP3 inflammasome in diabetes and COVID-19 role of NLRP3 inflammasome in the pathogenesis and treatment of COVID-19 and diabetes NLRP3 inflammasome in diabetes and COVID-19 intervention
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85. Palmitoleic acid protects microglia from palmitate-induced neurotoxicity in vitro
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89. Schisandrin B Alleviates Diabetic Cardiac Autonomic neuropathy Induced by P2X7 Receptor in Superior Cervical Ganglion via NLRP3
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90. Blockage of P2X7R suppresses Th1/Th17-mediated immune responses and corneal allograft rejection via inhibiting NLRP3 inflammasome activation
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91. Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes
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94. Effect of a combination of Atractylodes macrocephala extract with strychnine on the TLR4/NF‑κB/NLRP3 pathway in MH7A cells
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95. Research and progress of inflammasomes in nonalcoholic fatty liver disease
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96. Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures
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97. Mechanism of DaiTongXiao in the treatment of gouty arthritis through the NLRP3 signaling pathway
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98. Punicalagin suppresses inflammation in ventilator‐induced lung injury through protease‐activated receptor‐2 inhibition‐induced inhibition of NLR family pyrin domain containing‐3 inflammasome activation
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99. Protein Profiling of a Cellular Model of NAFLD by Advanced Bioanalytical Approaches
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100. The role of NLRP3 inflammasome in digestive system malignancy
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