NLRP3 inflammasome and its inhibitors: a review

Shao, Bo-Zong, Xu, Zhe-Qi, Han, Bin-Ze, Su, Ding-Feng, Liu, Chong·2015·Frontiers in Pharmacology

DOI 10.3389/fphar.2015.00262

Cited by (838)

Items 801–838 of 838

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Additional file 1 of Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells
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Additional file 2 of Molecular mechanisms of AMPK/YAP/NLRP3 signaling pathway affecting the occurrence and development of ankylosing spondylitis
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Additional file 1 of Subcutaneous adipose tissue alteration in aging process associated with thyroid hormone signaling
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Current Trends in Computational Methods to Discover New Anti-inflammatory Agents Targeting NLRP3 Complex
Karla Joane da Silva Menezes, Fernanda de França Genuíno Ramos Campos, Arthur Gabriel Corrêa de Farias, Wallyson Junio Santos de Araújo, Igor José dos Santos Nascimento, Ricardo Olimpio de Moura · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
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Immune-targeted therapies: Management of diabetes and fostering healthy aging
Firzan Nainu, Youdiil Ophinni, Sukamto Salang Mamada, Nadila Pratiwi Latada · 2026 · Elsevier eBooks
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Cacylde Amouzou · 2016 · theses.fr (ABES)
Exposition précoce aux toxiques et déséquilibres nutritionnels : l’inflammation et les lésions précancéreuses de la prostate
Katia Gharieb · 2017
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Gwenaëlle Le Menn · 2018 · theses.fr (ABES)
Rôle des monocytes dans la régulation de la réponse inflammatoire au cours du sepsis
Camille Baudesson de Chanville · 2018
Molecular and cellular bases of systemic autoinflammatory disorders including Adult-onset Still’s disease
Eman Assrawi · 2019
Mécanismes impliqués dans l'activité pro- et anti-inflammatoire des "Neutrophil Extracellular Traps" : implications physiopathologiques dans la polyarthrite rhumatoïde
Sarra Seninet · 2018 · theses.fr (ABES)
Impact de l'inflammation périnatale sur le cerveau en développement : de la dimension neurodéveloppementale à l'échelle endothéliale
Antoine Giraud · 2020
cGAMP-VLP : optimization of production, functional studies, and development of a second generation
Aurore Bochnakian · 2020
The NLRP3 Inflammasome: A Central Mediator in Sevoflurane-Induced Neurotoxicity and A Potential Target for Neuroprotection
Nuan Li, Yeru Chen, Gang Chen · 2026 · Molecular Neurobiology
Targeted protein degradation in inflammatory bone diseases: Mechanistic basis and therapeutic opportunities
Yu-Xuan Wu, Yuan-Hao Wen, Qiu-Hui Li, Lu Zhang · 2026 · Translational research
Intra-articular metformin and chlorogenic acid synergistically protect against cartilage degeneration by suppressing NF-κB/NLRP3 inflammasome axis in osteoarthritis
Mona A. Abdel‐Kareem, Nourhan Abd-Elrafea, Walied Abdo, Ayman S. Atiba, Rasha A. Elsisy, Sulaiman Mohammed Alnasser, Reem Saleh Alruhaimi, Ayman Moawad Mahmoud, Amira E. Farage · 2026 · Tissue and Cell
Computational evaluation of NOD-like receptor pyrin domain-containing 3 inflammasome inhibitors for endodontic inflammation: A molecular docking analysis of synthetic and phytochemical compounds
Ameesha S Rai, Raksha Bhat, Mahendra Gowdru Sriniv, Shreya Kanchan, Preethesh Shetty · 2026 · Journal of Conservative Dentistry and Endodontics
Juglone Attenuates CCl₄‐Induced Hepatic Injury in Mice With Associated Modulation of Oxidative Stress and Inflammasome‐Related mRNA Expression
Aamir Sohail, Raza Sufyan, Muhammad Asim, MA Khan, Aleena Altaf, Muhammad Ehsan Ul Haq, Maimoona Arshad, Atif Ali Khan Khalil, Imran Ullah · 2026 · BioMed Research International
Small-molecule inhibitors targeting the NLRP3 inflammasome: advances since mid-2023 and future perspectives
Donghao Jia, Yunlei Hou, Yue Wu, Yang Zhang, Yanfang Zhao, Ping Gong · 2026 · RSC Medicinal Chemistry
ULTRASTRUCTURAL FEATURES OF PROGRAMMED CELL DEATH SPECIES: APOPTOSOME, INFLAMMASOME, AUTOPHAGOSOME
David A. Areshidze, Maria A. Kozlova · 2026 · Morphology
Targeting vascular inflammation and endothelial dysfunction with nanobodies: emerging therapeutic strategies for cardiovascular disease
Ibrahim Aljaezi · 2026 · Frontiers in Immunology
A sesterterpenoid derivative alleviates ulcerative colitis through targeting ProRS to suppress the NLRP3 inflammasome
Man Li, Han Zhang, Ran Fu, Linxi Mao, Yu Zheng, Liang-Liang Wang, Yanchun Liu, Ting-Ting Zhou, Rong‐Fang Mu, Hong Hu et al. · 2026 · Science China Life Sciences
Dysregulated autophagy in osteoarthritis: Mechanisms, regulation by non-coding RNAs, and therapeutic implications.
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Structural Characterization and Immunological Activity of Polysaccharides Extracted from Ulva pertusa Fermented by Bacillus velezensis
Jieting Yu, Simon Wing-Fai Mok, Qin Liu, Xiaoyong Zhang, lo Nam Wong, Kit Ian Kou, Ammad Ahmad Farooqı, Saiyi Zhong, Jun Liu, Riming Huang · 2026 · Journal of Agricultural and Food Chemistry
ROS–NLRP3 Inflammasome Axis in Obesity: A Critical Review of Oxidative Stress-Driven Inflammation and Emerging Therapeutic Strategies
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Activation of Platelet Caspase‐1 and P‐Selectin Over‐Expression in Sickle Cell Disease Patients: An Involvement of NLRP3 Inflammasome?
Livia Claude, Frédéric Martino, Lydiane Mordier, Doris Célanie, Emmanuelle Bernit, Maryse Etienne‐Julan, B. Tressières, Marc Romana, Véronique Baccini · 2026 · Journal of Cellular and Molecular Medicine
BindingDB Entry 50023323: Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor.
BindingDB · 2026 · UC San Diego
BindingDB Entry 50003002: Structural Insights of Benzenesulfonamide Analogues as NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
BindingDB · 2020 · UC San Diego
BindingDB Entry 50011366: Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor.
BindingDB · 2022 · UC San Diego
BindingDB Entry 50009661: Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
BindingDB · 2021 · UC San Diego
BindingDB Entry 50010395: Discovery of
BindingDB · 2021 · UC San Diego
NLRP3 inflammasome dysregulation in chronic bacterial infections: mechanistic insights into treatment failure and relapse
Jashan Girdhar, Sarita Jangra, Apoorv Rastogi, Richa Saxena · 2026 · Human Immunology