NLRP3 inflammasome and its inhibitors: a review

Shao, Bo-Zong, Xu, Zhe-Qi, Han, Bin-Ze, Su, Ding-Feng, Liu, Chong·2015·Frontiers in Pharmacology

Cited by (838)

Items 601–700 of 838

  1. Cryopyrin-Associated Periodic Syndromes (CAPS)
    Hal M. Hoffman, Jasmin Beate Kuemmerle-Deschner, Raphaela T. Goldbach‐Mansky · 2019 · Springer eBooks
  2. Genetic contribution and functional impairment of inflammasome in sickle cell disease
    Valéria de Freitas Dutra, Vinícius Nunes Cordeiro Leal, Fernanda Pereira Fernandes, Cláudia Regina Lustosa Souza, Maria Stella Figueiredo, Alessandra Pontillo · 2021 · Cytokine
  3. Effects of acetate-producing Blautia wexlerae on oxidative stress and NLRP3 inflammasome in obesity-associated male infertility
    Yucheng Zhong, Hao Deng, Jun Zhao, Guoqun Luo, Huan Li · 2024 · Medical Microbiology and Immunology
  4. Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation
    Ying Wu, Qingling Guo, Yongping Liu, Xun Gong, Wei Sun, Yushu Li, Chenling Fan, Weiping Teng, Zhongyan Shan · 2024 · Endocrine Connections
  5. Organogermanium: Potential beneficial effects on the cardiovascular system
    Kunihiko Aizawa, Takashi Nakamura, Yasuhiro Shimada, Tomoya Takeda, Junya Azumi, Angela C. Shore · 2025 · Physiological Reports
  6. A review on NLRP3 inflammasome modulation by animal venom proteins/peptides: mechanisms and therapeutic insights
    Akshad Balde, Soottawat Benjakul, Rasool Abdul Nazeer · 2025 · Inflammopharmacology
  7. Cellular Immunity in Obesity: Pathophysiological Insights and the Impact of Bariatric Surgery
    Tania Rivera-Carranza, Angélica León-Téllez Girón, Raquel Gónzalez-Vázquez, Paola Vázquez-Cárdenas, Ana Laura Esquivel-Campos, Felipe Mendoza‐Pérez, Martin Rojano‐Rodriguez, Claudia Mimiaga-Hernández, Juan Carlos Cifuentes-Goches, Omar Edgar Peralta Valle et al. · 2025 · International Journal of Molecular Sciences
  8. Advances in the Understanding of Mitochondrial Inflammatory Regulation in the Pathogenesis of Alzheimer’s Disease
    Ren-Zhen Zhang, Li Li, Cui Ma, Tingting Dou, Yu-Ting Wei, Xingke Yan · 2025 · Journal of Inflammation Research
  9. FOXQ1 inhibits the progression of osteoarthritis by regulating pyroptosis
    Zhihuan Luo, Hui Zeng, Kanghua Yang, Yihai Wang · 2024 · Aging
  10. Inflammasome-Inhibiting Nanoligomers Are Neuroprotective against Space-Induced Pathology in Healthy and Diseased Three-Dimensional Human Motor and Prefrontal Cortex Brain Organoids
    Sadhana Sharma, Vincenzo S. Gilberto, Jon C. Rask, Anushree Chatterjee, Prashant Nagpal · 2024 · ACS Chemical Neuroscience
  11. Comparative Analysis of Immune Response Genes Induced by a Virulent or Attenuated Strain of Babesia bigemina
    Grecia Martínez-García, Karel Estrada, José Juan Lira-Amaya, Rebeca Montserrat Santamaria-Espinosa, Ma. Eugenia López-Arellano, Edda Sciutto, Carmen Rojas-Martínez, Jesús A. Álvarez-Martínez, Alejandro Sánchez‐Flores, Julio Vicente Figueroa Millán · 2025 · International Journal of Molecular Sciences
  12. Du Huo Ji Sheng Tang relieves knee osteoarthritis via suppressing NLRP3/NF-κB inflammatory signals in rats
    Wenjin Chen, Jianwei Wang, Zhen Hua, Yafeng Zhang · 2020 · European Journal of Inflammation
  13. Mist1 promoted inflammation in colitis model via K+-ATPase NLRP3 inflammasome by SNAI1
    Tao Wang, Wenxiang Liu, Chenyang Li, Guowei Si, Zhimin Liang, Jian Yin · 2021 · Pathology - Research and Practice
  14. Acetoacetate is a trigger of NLRP3 inflammasome activation in bovine peripheral blood mononuclear cells
    Yuri Onizawa, Taiga Katoh, Ryotaro Miura, Kunitoshi Konda, Tatsuo NOGUCHI, Hisataka Iwata, Takehito Kuwayama, Seizo Hamano, Koumei Shirasuna · 2021 · Veterinary Immunology and Immunopathology
  15. Immune System, Gut Microbiota and Diet: An Interesting and Emerging Trialogue
    Marianna Roselli, Raffaella Canali, Alberto Finamore, Andrea Ghiselli, Chiara Devirgiliis · 2022 · IntechOpen eBooks
  16. Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome
    Xiaoli Cui, Ruihua Jia, Rui Zhao, Ni Ma, Feng Jiang · 2023 · Neurochemical Research
  17. Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome
    Luchen Zhang, Guoyang Li, Bolong Lin, Hongbin He, Rongbin Zhou, Wei Jiang · 2024 · International Immunopharmacology
  18. RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice
    Man Liu, Yinglin Yang, Shanshan Zhang, Dong-Ni Liu, Lian‐Hua Fang, Guanhua Du, Yuehua Wang · 2021 · Marine Drugs
  19. Pannexin1 channels in the liver: an open enemy
    Raf Van Campenhout, Anne Caufriez, Andrés Tabernilla, Amy Maerten, Sybren De Boever, Julen Sanz-Serrano, Prashant H. Kadam, Mathieu Vinken · 2023 · Frontiers in Cell and Developmental Biology
  20. Research Progress in the Molecular Mechanism of NLRP3 Inflammasome in Alzheimer’s Disease and Regulation by Natural Plant Products
    Runru Zu, Lu Hao, Wanting Liu, Simai Shao, Jiayao Zheng, Xiran Ying, Yangang Zhou, Zhonghua Li, Wang Wang, Dejuan Li et al. · 2025 · Molecular Neurobiology
  21. Deciphering the NLRP3 inflammasome in diabetic encephalopathy: Molecular insights and emerging therapeutic targets
    Xinyi Zeng, Yi Yuan, Yujia Li, Ziyan Hu, Shan Hu · 2025 · Experimental Neurology
  22. The Role of NLRP3, a Star of Excellence in Myeloproliferative Neoplasms
    Elisa Parciante, Cosimo Cumbo, Luisa Anelli, Antonella Zagaria, Immacolata Redavid, Angela Minervini, Maria Rosa Conserva, Giuseppina Tota, Nicoletta Coccaro, Francesco Tarantini et al. · 2023 · International Journal of Molecular Sciences
  23. Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis
    Jiahao Chen, Wu Luo, Chenghong Hu, Miao Ren, Haowen Xu, Xiangwei Xu, Weifeng Li, Yue Chen, Jingjing Shao, Zhongxiang Xiao et al. · 2023 · International Immunopharmacology
  24. Jia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice
    Xiaolu Zhang, Yingxin Sun, Qun Yu, Wenyun Zeng, Yue Zhang, Miao Zeng, Kexin Pang, Yifei Yu, Jiali Gan, Huhu Li et al. · 2023 · Mediators of Inflammation
  25. A comprehensive computational study of Millets derived phytochemicals as potential inhibitors of NACHT domain of NLRP3 inflammasome: Molecular docking, molecular dynamics simulation, MM-PBSA free energy calculation and DFT analysis
    Nasiruddin Nalban, Manish wanjari, Sudhir Matte, Pallavi Jamadagni, Munaf Tamboli · 2024 · Indian Journal of Biochemistry and Biophysics
  26. Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress
    Yaqin Chai, Xing Gu, Hongjun Zhang, Xinting Xu, Lizhan Chen · 2024 · Aging
  27. Role of Oxysterols in the Activation of the NLRP3 Inflammasome as a Potential Pharmacological Approach in Alzheimer's Disease
    Gabriela L. Martins, Cláudia N. Ferreira, András Palotás, Natália P. Rocha, Helton J. Reis · 2022 · Current Neuropharmacology
  28. IL-9 blockade attenuates inflammation in a murine model of mechanical ventilation-induced lung injury by inhibiting the NLRP3 inflammasome pathway
    Tao Wang, Ziqi Chai, Lijuan Wang, Bo Liu, Junbo Zhao, Jie Ren, Bo Yang, Xiaoyong Wei, Lihua Jiang, Fuyun Liu · 2022 · Inflammopharmacology
  29. Oxymatrine blocks the NLRP3 inflammasome pathway, partly downregulating the inflammatory responses of M1 macrophages differentiated from THP-1 monocytes
    Ke Zhang, Youyang Liu, Yunlu Zhao, Qi Guo, Shengjun An, Shuhui Wu · 2023 · Biochemistry and Biophysics Reports
  30. Tooth loss impairs cognitive function in SAMP8 mice via the NLRP3 /Caspase‐1 pathway
    Xu Sun, Yunping Lu, Qian Pang, Bin Luo, Qingsong Jiang · 2023 · Oral Diseases
  31. Effects of the mineralocorticoid receptor antagonist eplerenone in experimental autoimmune encephalomyelitis
    Guido S. Alvarez Quintero, Analia E. Lima, Paulina Roig, María Meyer, E. R. de Kloet, Alejandro Federico De Nicola, Laura I. Garay · 2024 · The Journal of Steroid Biochemistry and Molecular Biology
  32. Anoectochilus roxburghii polysaccharide reduces D-GalN/LPS-induced acute liver injury by regulating the activation of multiple inflammasomes
    Yulu Yan, Xiqi Ye, Huang Chunqing, Junjun Wu, Yunbiao Liu, Pingping Zheng, Congqi Shen, Zhaofang Bai, Shen Tingming · 2024 · Journal of Pharmacy and Pharmacology
  33. Walking over the inflammasome
    Oliver Gorka, Emilia Neuwirt, Olaf Groß · 2019 · Nature Chemical Biology
  34. Investigating the impact of mitochondrial DNA : Insights into blood transfusion reactions and mitigation strategies
    Saeede Bagheri, Fatemeh Hajiabadi, Reihaneh Vahabzadeh, Mohammad Hossein Ahmadi · 2025 · Vox Sanguinis
  35. Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome
    Lingmei Li, Ce Cao, Hao Guo, Lin Li, Lei Li, Yehao Zhang, Gaojie Xin, Zixin Liu, Shujuan Xu, Han Xiao et al. · 2025 · BMC Complementary Medicine and Therapies
  36. The NLRP3 activation-related signature predicts the diagnosis and indicates immune characteristics in endometriosis
    Weihua Nong, Huimei Wei, Sheng Dou, Liqiao He, Luping Lin, Donglin Lu, Bixiao Wei, Shun Zhang, Peng Huo, Mingyou Dong · 2025 · Journal of Reproductive Immunology
  37. Inhibitors of inflammasome (NLRP3) signaling pathway as promising therapeutic candidates for oral cancer
    Shreya Agrawal, Shatakshi Narang, Yadvendra Shahi, Sayali Mukherjee · 2025 · Biochimica et Biophysica Acta (BBA) - General Subjects
  38. The role of alpha-pinene on the NLRP3-Caspase 1 pathway in the ulcerative colitis model in rats
    Kaveh Rahimi, Annahita Rezaie, Arian Javadi, Mahsa Khademi Kalantari, Negar Eftekhar, Hoora Shushtari · 2025 · Tissue and Cell
  39. Innate Immune Signaling in Gliomas: Regulatory Mechanisms and Targeting Potential in Tumor Progression
    Edmund Jung, Sara Al Jadidi, Christina Piperi · 2025 · Life
  40. Pyroptosis in Ischemic Stroke: Roles, Mechanisms, and Therapeutic Strategies
    Tingting Qi, Zhen Xiao, Yufeng Peng, Yinjuan Zhou, Wen Wang, Changxi Li, Jinhao Kang, Tingting Zhao, Guoming Mao, Yujie Weng et al. · 2026 · Restorative Neurology and Neuroscience
  41. Methods to Activate the NLRP3 Inflammasome
    Benedikt S. Saller, Emilia Neuwirt, Olaf Groß · 2023 · Methods in molecular biology
  42. Diagnosis of Canine Tumours and the Value of Combined Detection of VEGF, P53, SF and NLRP3 for the Early Diagnosis of Canine Mammary Carcinoma
    Ning-Yu Yang, Hui-Hua Zheng, Chao Yu, Yan Ye, Guang-Hong Xie · 2024 · Animals
  43. Gut Microbiota Alleviates Intestinal Injury Induced by Extended Exposure to Light via Inhibiting the Activation of NLRP3 Inflammasome in Broiler Chickens
    Dandan Ma, Minhong Zhang, Jinghai Feng · 2024 · International Journal of Molecular Sciences
  44. tVNS alters inflammatory response in adult VPA ‐induced mouse model of autism: evidence for sexual dimorphism
    Hale Gök Dağıdır, Neslihan Celik Bukan, Meltem Bahçelioğlu, Ayşen Çalıkuşu, Ece Alim, Saadet Özen Akarca Dizakar, Elif Topa, Hayrünnisa Bolay · 2024 · FEBS Open Bio
  45. The role of NLRP3 inflammasome in multiple sclerosis: pathogenesis and pharmacological application
    Wengang Zhang, Xiao-Rui Zheng, Yi Yao, Weijia Sun, Bo‐Zong Shao · 2025 · Frontiers in Immunology
  46. Expression and predictive value of NLRP3 in patients with atrial fibrillation and stroke.
    Jue Sun, Jiayi Xu, Qianhong Yang · 2022 · PubMed Central
  47. Brown adipose tissue-derived Nrg4 alleviates non-alcoholic fatty liver disease in mice
    Jing Luo, Ming Chen, Hongwu Ji, Weifeng Su, Wenkui Song, Di Zhang, Weiming Su, Shucheng Liu · 2023 · Journal of Functional Foods
  48. The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro
    Shanshan Wang, Fei Ye, Qingjia Ren, Shengnan Sun, Weina Xia, Zhuwei Wang, Haolin Guo, Han Li, Shujing Zhang, Scott Lowe et al. · 2023 · Journal of Ethnopharmacology
  49. Clinical characteristics of Chinese neonates with neonatal-onset multisystem inflammatory disease: a case report and literature review
    Cui Zhao, Chen Liu, Xiao-Ying Li · 2024 · Frontiers in Immunology
  50. Combined developmental exposure to estrogenic endocrine disruptor and nutritional imbalance induces long term adult prostate inflammation through inflammasome activation
    Katia Gharieb, Nezli Doumandji, Wafa Bensalem, Rachel Paul, Lilia Inoubli, Bénazir Siddeek, Alexandra Traverse‐Glehen, Myriam Decaussin‐Petrucci, Michèle Trabucchi, Mohamed Benahmed et al. · 2024 · Toxicology Letters
  51. Morbus Still im Kindes- und Erwachsenenalter
    Christian Michael Hedrich, Claudia Günther, Martin Aringer · 2017 · Der Hautarzt
  52. The Role of Inflammasomes in Ovarian Cancer
    Bárbara da Silva Martins, Roberto Silva Ribeiro, Tatiana Massariol Pimenta, Josiany Carlos de Souza, Letícia Batista Azevedo Rangel · 2022 · Exon Publications eBooks
  53. The NLRP3 Inflammasome in Age-Related Cerebral Small Vessel Disease Manifestations: Untying the Innate Immune Response Connection
    Che Mohd Nasril Che Mohd Nassir, Thenmoly K Damodaran, Nurul Iman Ismail, Sabarisah Hashim, Usman Jaffer, Hafizah Abdul Hamid, Muhammad Zulfadli Mehat, Anwar Norazit, Muzaimi Mustapha · 2023 · Life
  54. Avanafil Mitigates Testicular Ischemia/Reperfusion Injury via NLRP3 Pathway Modulation in Rats
    Muhammet Çelik, Pelin Aydın, M. S. Civelek, Nurullah Akgun, Zeynep Karakoy, Cihad Ozcelik, Gulchin Tanri̇verdi̇yeva, Erdem Toktay · 2024 · Reproductive Sciences
  55. Do inflammasome impact COVID-19 severity?
    Maria Beatriz Calado, Crislayne Emilly da Silva Santana, Sérgio Crovella · 2021 · VirusDisease
  56. Therapeutic Targeting of Inflammatory Pathways with Emphasis on NLRP3 Inflammasomes by Natural Products: A Novel Approach for the Treatment of Inflammatory Eye Diseases
    Amro Mohamed Soliman, Ru Hui Sim, Srijit Das, Pasuk Mahakkanukrauh · 2021 · Current Medicinal Chemistry
  57. Quanzhen Yiqi decoction attenuates inflammation in mice with smoking-induced COPD by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome
    Jiamin Zeng, Zhenqiu Li, Wanyan Li, Zhu Liang, Yuewen Luo, Caiping Li, Sida Liao, Kexin Wang, Yuanlong Hu, Yuanyuan Li et al. · 2024 · Journal of Pharmacy and Pharmacology
  58. Estrogen receptor is involved in the osteoarthritis mediated by ATG16L1-NLRP3 activation
    Faxue Liao, Shuo Yang, Zhi-Hong Liu, Kaida Bo, Pengfei Xu, Jun Chang · 2024 · Joint Diseases and Related Surgery
  59. Effect of NLRP3 inflammasome induced astrocyte phenotype alteration in morphine tolerance
    Zhenyu Yuan, Bo-Xuan Lu, Meiling Zhang, Yinxiao Lu, Zhihui Wang, Wenhao Zhang, Hao Cheng, Zhifang Wu, Qing Ji · 2024 · Frontiers in Pharmacology
  60. Protective effects of Dendrobium candidum Wall ex Lindl. on high‐fat diet‐induced liver damage in mice
    Xiong‐Zhang Yin, Wei‐Ming Chi, Ling Zhang, Y.-X. Su, Zhongyuan Zhang, Chengbin Xue · 2021 · Journal of Food Biochemistry
  61. The Function of Spag6 to Repair Brain Edema Damage After Cerebral Ischemic Stroke-reperfusion
    Yiming Hu, Xiaolu Cao, Yujie Zhao, Jin Yang, Fengqin Li, Bingmei Xu, Minghui Zhao, Yajun Chen, bingxue du, Yu Sun et al. · 2023 · Neuroscience
  62. Efficacy of traditional Chinese medicine on diabetic cardiomyopathy in animal models: a systematic review and meta-analysis
    Longxiao Hu, Longxin Qian, Aochuan Sun, Guida Cai, Yunxiao Gao, Yue Yang Yuan, Xiaoxiao Chen, Yunyao Jiang, Jianxun Liu, Junguo Ren · 2023 · Frontiers in Pharmacology
  63. Retinoic acid ameliorates low-grade endotoxemia-induced mastitis by limiting inflammatory responses in mice
    Keyi Wu, Shan Shang, Lijuan Bao, Yihong Zhao, Zhihang Guan, Jiawen Xu, Hao Sun, Weijie Yuan, Yunhe Fu, Lu-Yuan Peng et al. · 2023 · Microbial Pathogenesis
  64. The critical role of NLRP3 in drug resistance of cancers: Focus on the molecular mechanisms and possible therapeutics
    Beena Briget Kuriakose, Ahmed Hussein Zwamel, Ayad Abdulrazzaq Mutar, Subasini Uthirapathy, Ashok Kumar Bishoyi, Kandi Satyam Naidu, Ahmed M. Hjazi, Prashant Nakash, Renu Arya, Sami G. Almalki · 2025 · Seminars in Oncology
  65. Scutellaria baicalensis Georgi in metabolic-associated fatty liver disease treatment: research progress
    Liping Chen, Enhe Liu, Xi Zhao, Xiao Liu, Qin Dong, Yinpei Lou, Guoying Huang, Ling Li, Yuxin He · 2025 · Frontiers in Pharmacology
  66. Energy Provisioning and Inflammasome Activation: The Pivotal Role of AMPK in Sterile Inflammation and Associated Metabolic Disorders
    Akhila Hosur Shrungeswara, Mazhuvancherry Kesavan Unnikrishnan · 2020 · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
  67. Postexercise Inflammasome Activation and IL-1β Production Mitigated by Flavonoid Supplementation in Cyclists
    David Christopher Nieman, Francesca Ferrara, Alessandra Pecorelli, Brittany L. Woodby, Andrew T. Hoyle, Andrew W. Simonson, Giuseppe Valacchi · 2020 · International Journal of Sport Nutrition and Exercise Metabolism
  68. The Effect of 5-Aminolevulinic Acid Photodynamic Therapy in Promoting Pyroptosis of HPV-Infected Cells
    Junxiao Wei, Xiaoming Peng, Sijia Wang, Meinian Xu, Hui Liu, Yixiu Zhong, Xi Chen, Qi Wang, Xiaowen Huang, Kang Zeng · 2022 · Photonics
  69. Pathophysiological Abnormalities in Migraine Ameliorated by Ketosis: A Proof-of-Concept Review
    Panitda Huynh, Pasquale Calabrese · 2022 · Journal of Integrative Neuroscience
  70. Trehalose prevents glyphosate-induced hepatic steatosis in roosters by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation
    Cai-Yu Lian, Run-Zhou Wang, Jie Wang, Zhen‐Yong Wang, Wei Zhang, Lin Wang · 2022 · Veterinary Research Communications
  71. A study on the level of NLRP3 inflammasome in patients with premature rupture of membranes
    Fen Xue, Yan Wang, Xue‐Qiang Tao, Wei Su · 2023 · Immunity Inflammation and Disease
  72. The Mechanism of Astragaloside IV in NOD-like Receptor Family Pyrin Domain Containing 3 Inflammasome-mediated Pyroptosis after Intracerebral Hemorrhage
    Honggang Wu, Shu Chen, Guoliang You, Bo Lei, Li Chen, Jiachuan Wu, Niandong Zheng, Chao You · 2024 · Current Neurovascular Research
  73. From property of IL-1β to imaging of inflammation
    Takao Iwawaki · 2017 · Japanese Journal of Clinical Immunology
  74. Proteína 3 contendo um domínio NACHT, porção C-terminal rica em repetições de leucina e de domínio pirina e LL-37: valor prognóstico de novos biomarcadores em pneumonia adquirida na comunidade
    Chuanan Zhu, Yingfan Zhou, Jiabin Zhu, Ye Liu, Mengyi Sun · 2019 · Jornal Brasileiro de Pneumologia
  75. Dementia risk genes engage gene networks poised to tune the immune response towards chronic inflammatory states
    Jessica E. Rexach, Vivek Swarup, Timothy S. Chang, Daniel H. Geschwind · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  76. Symptoms, molecular markers and mechanisms in the development of coronary artery disease in individuals with post-traumatic stress disorder
    Wọlé Akóṣílè · 2021 · Queensland University of Technology
  77. EB1089 promotes the expression of vitamin D receptor in the intestinal epithelial cell line HT-29 and reduces lipopolysaccharide-induced inflammatory response
    Dong Lu, Minghui Yu, Lu Chen, Jianqiang Ye, Liquan Huang, Guangwei Zhu, Bin Lan · 2022 · Annals of Translational Medicine
  78. Elucidating the molecular landscape of tendinitis: the role of inflammasome-related genes and immune interactions
    Hongwei Xu, Xiaolang Lu, Yu Pu Yang, Yifei Zhou, Tengfei Qi, Yijing Zheng · 2024 · Frontiers in Immunology
  79. Future Therapeutics: Targeting the NLRP3 Inflammasome Pathway to Manage Diabetic Retinopathy Development and Progression
    Charisse Y. J. Kuo, Ilva D. Rupenthal, Rinki Murphy, Odunayo Omolola Mugisho · 2024 · International Journal of Translational Medicine
  80. 13,14-Seco Withaphysalins from Physalis Minima and Their Inhibitory Effects on Nlrp3 Inflammasome Activation
    Bintao Hu, Xia Peng, Chunping Tang, Meiyu Geng, Sheng Yao, Jing Ai, Yang Ye · 2024 · Bioorganic Chemistry
  81. Renogrit selectively protects against cisplatin-induced injury in human renal tubular cells and in Caenorhabditis elegans by harmonizing apoptosis and mitophagy
    Acharya Balkrishna, Vivek Gohel, Nishit Pathak, Monali Joshi, Rani Singh, Ankita Kumari, Rishabh Dev, Anurag Varshney · 2024 · Scientific Reports
  82. MicroRNA ‐223 alleviates inflammatory response in renal ischemia‐reperfusion injury by targeting NLRP3
    Jun Ye, Xiaoli Tang, Ming Li, Yutian Liao, Yiqian Zeng, Furong Tang, Eryue Qiu · 2024 · The Kaohsiung Journal of Medical Sciences
  83. Pyroptosis of periodontal ligament stem cells aggravates periodontitis via Piezo1 channel
    Peng Chen, Duo Liu, Yikun Zhou, Jiuhui Jiang, Ruili Yang · 2025 · iScience
  84. Effect of Vitamin D3 on the Levels of Oxidative Stress and Expression of the NLRP3 Inflammatory Gene in Type 2 Diabetes Mellitus: A Randomized Clinical Trial
    Shadi Behshad, Yaser Mohammadi, Gholamreza Anani Sarab, Mohammad Malekaneh, Azam Rezaei Farimani · 2025 · Health Science Reports
  85. Streptococcus salivarius -derived ilexgenin A alleviates pneumonia through the gut-lung axis
    Xintao Huang, Rong Wu, Xiaoqi Liang, Zhichao Yu, Ping Qin, Ze Wang, Peiheng Guo, Yunong Zeng, Zhengzheng Yan, Wei Lie Xiao et al. · 2025 · mSystems
  86. Mechanisms of NLRP3 inflammasome in pathogenesis and progression of inflammation-related gastrointestinal diseases
    Fengmei Liu, Bo‐Zong Shao, Yaqin Zhu, Xiaochun Xue, Xiaoyan Wu · 2025 · PeerJ
  87. Uncovering the ATP-Dependent Activation Mechanism of NLRP3 through Integrated Computational Approaches
    Guanyi Li, Yuxuan Wang, Yijing Zhang, Zhengzhong Kang, Yaxue Zhao · 2025 · Journal of Chemical Information and Modeling
  88. USP16 drives psoriasis progression by deubiquitinating and stabilizing NLRP3 in keratinocytes
    Nan Wang, Fangqian Guan, Yifan Lin, Bohao Sun, Jindan Dai, Xiejun Xu, Weibo Tang, Yanhua Ren, Xuliang Huang, Wenjie Gao et al. · 2026 · JCI Insight
  89. The impact of inflammation, neuromodulation, and gut microbiota on developing cardiac fibrosis and hypertension
    Michał Kozdrowicki, Piotr Szczepaniak, V. F. Kyslyi, Lorenzo Carnevale, Daniela Carnevale, Giuseppe Lembo, Tomasz Jan Guzik, Tomasz P Mikolajczyk · 2026 · Cardiovascular Research
  90. Danger or Salvation? The Role of DAMPs in Cancer Therapy
    Anna A. Vedunova, Evgenii L. Guryev, Sergey V. Gudkov, Tatiana A. Mishchenko, Maria V. Vedunova · 2026 · Cancers
  91. Doxofylline: Advancing and Empowering Equitable Asthma and COPD Management Beyond Tradition
    Mario Cazzola, Clive Peter Page, Luigino Calzetta, Paola Rogliani, Maria Gabriella Matera · 2024 · Advanced Therapeutics
  92. Synthesis and Anti‐Inflammatory Bowel Disease Activity of Pterostilbene Derivatives
    Xingxing Zhang, Bin Li, Xiaohan Liu, Liuzeng Chen, Ban‐Feng Ruan, Chun Gu Xia · 2024 · Chemistry & Biodiversity
  93. Galantamine and wedelolactone combined treatment suppresses LPS-induced NLRP3 inflammasome activation in microglial cells
    Dilek Şaker, Leman Sencar, Gülfidan Çoşkun, Tuğçe Sapmaz, Derviş Mansuri Yılmaz, Sait Polat · 2024 · Immunopharmacology and Immunotoxicology
  94. Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3
    Suqin Zhong, Suzhen Zhong, Yi Guang Wu, Zhiyuan Liu, Yinyin Yang, Xinfeng Wang, Shanshan Li, Yu Wu, Xiaowan Huang, Yangyang Zhu et al. · 2025 · Journal of Controlled Release
  95. Porphyromonas Gingivalis Virulence Factors and their Role in Undermining Antimicrobial Defenses and Host Cell Death Programs in the Pathobiology of Chronic Periodontal Disease
    Alicja Płonczyńska, Zsombor Prucsi, Maja Sochalska, Jan Potempa · 2025 · Postępy Mikrobiologii - Advancements of Microbiology
  96. Vitamin C zum Schutz vor SARS-CoV-2 und zur Behandlung von COVID-19
    Madeleine Wehrmann · 2020 · Journal für Gynäkologische Endokrinologie/Schweiz
  97. Antioxidants and natural-derived products in the modulation of mitochondrial bioenergetics and dysfunction in chronic kidney disease models
    Omar Emiliano Aparicio‐Trejo, Edilia Tapia, Alfredo Briones‐Herrera, Elena Martínez‐Klimova, José Pedraza‐Chaverrí · 2020 · Elsevier eBooks
  98. Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
    L. Williams, Stephen G. Tristram, Graeme R. Zosky · 2020 · International Journal of Environmental Research and Public Health
  99. Effect of Hydrogen on AM Pyroptosis Induced by Severe Burns in Rats
    Ning Luo, Hua Lin, Linlin Zhang, Yi Jiang, Yue Zhao, Qingqing Han, Xin Wang, Yonghao Yu, Chao Qin · 2023 · Journal of Personalized Medicine
  100. Drugs Targeting NLRP3 Inflammasome in the Treatment of Diabetic Bone Disorders
    Yuyang Chen, Munire Aili, Fan Chen, Yu Gong, Xiaoju Chen, Lan Zhang · 2023 · Endocrine Metabolic & Immune Disorders - Drug Targets