Heartworm Disease (Dirofilaria immitis) in Two Roaming Dogs From the Urban Area of Castel Volturno, Southern Italy
Open accessAbstract
The zoonotic filarioid nematode Dirofilaria immitis is transmitted by bloodsucking mosquitoes and causes heartworm disease in dogs and wild canines. In the last decade D. immitis has spread in southern Europe including Italy. Few autochthonous foci of infection have been reported in previously non-endemic areas of southern Italy based only on the identification of microfilariae, antigen and serological tests and polymerase chain reaction assay from both the blood of dogs and mosquito vectors with no description of cases of heartworm disease in both domestic and wild canines. Here we report for first on two cases of heartworm disease found at post-mortem examination in two roaming dogs from the urban area of Castel Volturno in Campania region of southern Italy. Immunological analyses of 11 roaming dogs from the same pack of those two submitted for necropsy, and available necropsy data from the dogs recovered from the Campania region along the past 10 years were both negative for D. immitis infection. Although rare in southern Italy, these two cases are noteworthy because D. immitis may cause serious human infection. We highlight the need to identify the mosquito vectors of heartworm disease in this area using sensitive molecular assay for D. immitis DNA for predicting and controlling the spread of infection. We strongly recommend the control and systematic treatment of the domestic and roaming dogs that could constitute the most important infection reservoir.
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Santoro et al. reported two cases of heartworm disease in the Campania region of southern Italy.
“In addition, Santoro et al. [38] reported two cases of heartworm disease in the Campania region of southern Italy.”
From What has happened to heartworm disease in Europe in the last 10 years? (2022) · cites this paper as [38]
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What has happened to heartworm disease in Europe in the last 10 years?
Morchón, R., Montoya-Alonso, J. A., Rodríguez-Escolar, I., & Carretón, E. (2022) · Pathogens · doi:10.3390/pathogens11091042 · Cited by 69 · see citing works
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- Authors
- Santoro, M., Miletti, G., Vangone, L., Spadari, L., Reccia, S., & Fusco, G.
- Affiliations
- Istituto Zooprofilattico Sperimentale del Mezzogiorno (IT)
- Corresponding author
- Santoro, Mario
- Venue
- Frontiers in Veterinary Science
- Publisher
- Frontiers Media SA
- Published
- 2019-08-28
- Volume
- 6
- Pages
- 270-270
- ISSN
- 2297-1769 (ISSN-L)
- PMC
- PMC6722179
- OpenAlex
- W2965656582
- Cited by
- 10
- References
- 14
- Citations by year
- 2024: 1 · 2023: 6 · 2022: 1 · 2021: 2
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Veterinary Science (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Research on Leishmaniasis Studies
- Keywords
- heartworm disease, Dirofilaria immitis, zoonotic filariasis, mosquito vectors, autochthonous infection, Campania, reservoir of infection, postmortem diagnosis, serological testing
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