The Significance and Insignificance of Carbon Nanotube-Induced Inflammation

Metals, Toxicity and Oxidative Stress

Valko, M., Morris, H., & Cronin, M. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867053764635 · Cited by 5,018 · see citing works

Biomolecular coronas provide the biological identity of nanosized materials

Monopoli, M. P., Åberg, C., Salvati, A., & Dawson, K. A. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.207 · Cited by 3,017 · see citing works

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Dostert, C., Pétrilli, V., Van Bruggen, R., Steele, C., Mossman, B. T., & Tschopp, J. (2008) · Science · doi:10.1126/science.1156995 · Cited by 2,658 · see citing works

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

Poland, C. A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W., & Donaldson, K. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.111 · Cited by 2,645 · see citing works

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

Tenzer, S., Docter, D., Kuharev, J., Musyanovych, A., Fetz, V., Hecht, R., Schlenk, F., Fischer, D., Kiouptsi, K., Reinhardt, C., et al. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.181 · Cited by 2,283 · see citing works

Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation

Lam, C.-W. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg243 · Cited by 1,992 · see citing works

Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice

Shvedova, A. A., Kisin, E. R., Mercer, R., Murray, A. R., Johnson, V. J., Potapovich, A. I., Tyurina, Y. Y., Gorelik, O., Arepalli, S., Schwegler-Berry, D., et al. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00084.2005 · Cited by 1,312 · see citing works

Oxidative stress and apoptosis

Kannan, K., & Jain, S. K. (2000) · Pathophysiology · doi:10.1016/s0928-4680(00)00053-5 · Cited by 1,291 · see citing works

Time Evolution of the Nanoparticle Protein Corona

Casals, E., Pfaller, T., Duschl, A., Oostingh, G. J., & Puntes, V. (2010) · ACS Nano · doi:10.1021/nn901372t · Cited by 1,211 · see citing works

Respiratory toxicity of multi-wall carbon nanotubes

Muller, J., Huaux, F., Moreau, N., Misson, P., Heilier, J.-F., Delos, M., Arras, M., Fonseca, A., Nagy, J. B., & Lison, D. (2005) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2005.01.008 · Cited by 1,123 · see citing works

Translocation of bioactive peptides across cell membranes by carbon nanotubesElectronic supplementary information (ESI) available: details of the synthesis and characterization, cell culture, TEM, epifluorescence and confocal microscopy images of CNTs 1, 2 and fluorescein. See http://www.rsc.org/suppdata/cc/b3/b311254c/

Pantarotto, D., Briand, J., Prato, M., & Bianco, A. (2003) · Chemical Communications · doi:10.1039/b311254c · Cited by 1,100 · see citing works

Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants

Pulskamp, K., Diabaté, S., & Krug, H. F. (2006) · Toxicology Letters · doi:10.1016/j.toxlet.2006.11.001 · Cited by 1,003 · see citing works

Carbon nanotubes as intracellular protein transporters: generality and biological functionality.

Kam, N. W., & Dai, H. (2005) · Journal of the American Chemical Society · doi:10.1021/ja050062v · Cited by 985 · see citing works

Mechanisms in the Pathogenesis of Asbestosis and Silicosis

MOSSMAN, B. T., & CHURG, A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.5.9707141 · Cited by 971 · see citing works

Minireview: Nanoparticles and the Immune System

Zolnik, B. S., González-Fernández, A., Sadrieh, N., & Dobrovolskaia, M. A. (2010) · Endocrinology · doi:10.1210/en.2009-1082 · Cited by 914 · see citing works

The Nalp3 inflammasome is essential for the development of silicosis

Cassel, S. L., Eisenbarth, S. C., Iyer, S. S., Sadler, J. J., Colegio, O. R., Tephly, L. A., Carter, A. B., Rothman, P. B., Flavell, R. A., & Sutterwala, F. S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803933105 · Cited by 907 · see citing works

Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

Kagan, V. E., Konduru, N. V., Feng, W., Allen, B. L., Conroy, J., Volkov, Y., Vlasova, I. I., Belikova, N. A., Yanamala, N. V. K., Kapralov, A. A., et al. (2010) · Nature Nanotechnology · doi:10.1038/nnano.2010.44 · Cited by 796 · see citing works

Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single-Walled Carbon Nanotube Material

Maynard, A., Baron, P. A., Foley, M., Shvedova, A. A., Kisin, E. R., & Castranova, V. (2004) · Journal of Toxicology and Environmental Health · doi:10.1080/15287390490253688 · Cited by 763 · see citing works

Binding and Condensation of Plasmid DNA onto Functionalized Carbon Nanotubes: Toward the Construction of Nanotube-Based Gene Delivery Vectors

Singh, R. N., Pantarotto, D., McCarthy, D., Chaloin, O., Hoebeke, J., Partidos, C. D., Briand, J., Prato, M., Bianco, A., & Kostarelos, K. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0441561 · Cited by 759 · see citing works

Application of carbon nanotube technology for removal of contaminants in drinking water: A review

Upadhyayula, V. K. K., Deng, S., Mitchell, M. C., & Smith, G. B. (2009) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2009.09.027 · Cited by 723 · see citing works

Functionalized Carbon Nanotubes Are Non-Cytotoxic and Preserve the Functionality of Primary Immune Cells

Dumortier, H., Lacotte, S., Pastorin, G., Marega, R., Wu, W., Bonifazi, D., Briand, J., Prato, M., Muller, S., & Bianco, A. (2006) · Nano Letters · doi:10.1021/nl061160x · Cited by 697 · see citing works

Multi-walled carbon nanotubes induce T lymphocyte apoptosis

Bottini, M., Bruckner, S. R., Nika, K., Bottini, N., Stefano Bellucci, A., Magrini, A., Bergamaschi, A., & Mustelin, T. (2005) · Toxicology Letters · doi:10.1016/j.toxlet.2005.06.020 · Cited by 677 · see citing works

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

Shvedova, A. A., Kisin, E. R., Murray, A. R., Johnson, V. J., Gorelik, O., Arepalli, S., Hubbs, A. F., Mercer, R. R., Keohavong, P., Sussman, N., et al. (2008) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.90287.2008 · Cited by 643 · see citing works

Nanoparticle‐induced platelet aggregation and vascular thrombosis

Radomski, A. S., Jurasz, P., Alonso‐Escolano, D., Drews, M., Morandi, M. T., Maliñski, T., & Radomski, M. W. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706386 · Cited by 636 · see citing works

Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics

Klumpp, C., Kostarelos, K., Prato, M., & Bianco, A. (2005) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2005.10.008 · Cited by 542 · see citing works

Immunization with Peptide-Functionalized Carbon Nanotubes Enhances Virus-Specific Neutralizing Antibody Responses

Pantarotto, D., Partidos, C. D., Hoebeke, J., Brown, F., Kramer, E., Briand, J., Muller, S., Prato, M., & Bianco, A. (2003) · Chemistry & Biology · doi:10.1016/j.chembiol.2003.09.011 · Cited by 540 · see citing works

Scientific Status Summary

Brody, A. L., Bugusu, B. A., Han, J. H., Sand, C. K., & McHugh, T. H. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2008.00933.x · Cited by 536 · see citing works

Inhaled carbon nanotubes reach the subpleural tissue in mice

Ryman-Rasmussen, J. P., Cesta, M. F., Brody, A. R., Shipley-Phillips, J. K., Everitt, J. I., Tewksbury, E. W., Moss, O. R., Wong, B. A., Dodd, D. E., Andersen, M. E., et al. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.305 · Cited by 459 · see citing works

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

Ma-Hock, L., Treumann, S., Strauss, V., Brill, S., Luizi, F., Mertler, M., Wiench, K., Gamer, A. O., van Ravenzwaay, B., & Landsiedel, R. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp146 · Cited by 448 · see citing works

Complement activation and protein adsorption by carbon nanotubes

Salvador-Morales, C., Emmanuel Flahaut, B., Sim, E., Sloan, J., HGREEN, M., & Sim, R. B. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2005.02.006 · Cited by 433 · see citing works

Pulmonary and Systemic Immune Response to Inhaled Multiwalled Carbon Nanotubes

Mitchell, L., Gao, J., Wal, R. L. V., Gigliotti, A. P., Burchiel, S. W., & McDonald, J. D. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm196 · Cited by 433 · see citing works

Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps

Bergin, I. L., & Witzmann, F. A. (2013) · International Journal of Biomedical Nanoscience and Nanotechnology · doi:10.1504/ijbnn.2013.054515 · Cited by 412 · cited 6× · see citing works

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

Palomäki, J., Välimäki, E., Sund, J., Vippola, M., Clausen, P. A., Jensen, K. A., Savolainen, K., Matikainen, S., & Alenius, H. T. (2011) · ACS Nano · doi:10.1021/nn200595c · Cited by 408 · see citing works

Selective bone cell adhesion on formulations containing carbon nanofibers

Price, R. L., Waid, M. C., Haberstroh, K. M., & Webster, T. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00609-9 · Cited by 392 · see citing works

A cell nanoinjector based on carbon nanotubes

Chen, X., Kis, A., Zettl, A. K., & Bertozzi, C. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700567104 · Cited by 377 · see citing works

Raw Single-Wall Carbon Nanotubes Induce Oxidative Stress and Activate MAPKs, AP-1, NF-κB, and Akt in Normal and Malignant Human Mesothelial Cells

Pacurari, M., Yin, X. J., Zhao, J., Ding, M., Leonard, S. S., Schwegler-Berry, D., Ducatman, B. S., Sbarra, D., Hoover, M. D., Castranova, V., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10924 · Cited by 372 · see citing works

Enhanced functions of osteoblasts on nanometer diameter carbon fibers

Elias, K. L., Price, R. L., & Webster, T. J. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00087-x · Cited by 362 · see citing works

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

Jacobsen, N. R., Möller, P., Jensen, K. A., Vogel, U. B., Ladefoged, O., Loft, S. H., & Wallin, H. (2009) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-6-2 · Cited by 351 · see citing works

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

Murphy, F. A., Poland, C. A., Duffin, R., Al‐Jamal, K. T., Ali‐Boucetta, H., Nunes, A., Byrne, F., Prina‐Mello, A., Volkov, Y., Li, S., et al. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.02.040 · Cited by 322 · see citing works

Structural Defects Play a Major Role in the Acute Lung Toxicity of Multiwall Carbon Nanotubes: Physicochemical Aspects

Fenoglio, I., Greco, G., Tomatis, M., Muller, J. M., Raymundo‐Piñero, E., Béguin, F., Fonseca, A., Nagy, J. B., Lison, D., & Fubini, B. (2008) · Chemical Research in Toxicology · doi:10.1021/tx800100s · Cited by 303 · see citing works

Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model

Mercer, R. R., Scabilloni, J. F., Wang, L., Kisin, E. R., Murray, A. R., Schwegler‐Berry, D., Shvedova, A. A., & Castranova, V. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00186.2007 · Cited by 291 · see citing works

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

Demento, S. L., Eisenbarth, S. C., Foellmer, H. G., Platt, C., Caplan, M. J., Mark Saltzman, W., Mellman, I., Ledizet, M., Fikrig, E., Flavell, R. A., et al. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.03.034 · Cited by 290 · see citing works

Targeting carbon nanotubes against cancer

Fabbro, C., Ali‐Boucetta, H., Ros, T. D., Kostarelos, K., Bianco, A., & Prato, M. (2012) · Chemical Communications · doi:10.1039/c2cc17995d · Cited by 281 · see citing works

Cationic Carbon Nanotubes Bind to CpG Oligodeoxynucleotides and Enhance Their Immunostimulatory Properties

Bianco, A., Hoebeke, J., Godefroy, S., Chaloin, O., Pantarotto, D., Briand, J., Muller, S., Prato, M., & Partidos, C. D. (2004) · Journal of the American Chemical Society · doi:10.1021/ja044293y · Cited by 272 · see citing works

An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis

Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A. H., Walter, D. M., Walker, G. S., Scotchford, C. A., Donaldson, K., & Stone, V. (2007) · Carbon · doi:10.1016/j.carbon.2007.05.011 · Cited by 271 · see citing works

Material properties in complement activation

Moghimi, S. M., Andersen, A. J., Ahmadvand, D., Wibroe, P. P., Andresen, T. L., & Hunter, A. C. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.06.002 · Cited by 270 · see citing works

Pulmonary fibrosis: cytokines in the balance

Coker, R. K., & Laurent, G. J. (1998) · European Respiratory Journal · doi:10.1183/09031936.98.11061218 · Cited by 268 · see citing works

Complement in health and disease

Carroll, M. V., & Sim, R. B. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.06.005 · Cited by 265 · see citing works

Single-Walled and Multi-Walled Carbon Nanotubes Promote Allergic Immune Responses in Mice

Nygaard, U. C., Hansen, J. S., Samuelsen, M., Alberg, T., Marioara, C. D., & Løvik, M. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp057 · Cited by 263 · see citing works

Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

Ryman-Rasmussen, J. P., Tewksbury, E. W., Moss, O. R., Cesta, M. F., Wong, B. A., & Bonner, J. C. (2008) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0276oc · Cited by 261 · see citing works

Structural Defects Play a Major Role in the Acute Lung Toxicity of Multiwall Carbon Nanotubes: Toxicological Aspects

Muller, J., Huaux, F., Fonseca, A., Nagy, J. B., Moreau, N., Delos, M., Raymundo-Piñero, E., Béguin, F., Kirsch-Volders, M., Fenoglio, I., et al. (2008) · Chemical Research in Toxicology · doi:10.1021/tx800101p · Cited by 261 · see citing works

Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes

Mercer, R. R., Hubbs, A. F., Scabilloni, J. F., Wang, L., Battelli, L. A., Friend, S. A., Castranova, V., & Porter, D. W. (2011) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-8-21 · Cited by 259 · see citing works

Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes

Folkmann, J. K., Risom, L., Jacobsen, N. R., Wallin, H., Loft, S. H., & Möller, P. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11922 · Cited by 241 · see citing works

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes

Mercer, R. R., Hubbs, A. F., Scabilloni, J. F., Wang, L., Battelli, L. A., Schwegler‐Berry, D., Castranova, V., & Porter, D. W. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-28 · Cited by 236 · see citing works

Generation of superoxide (O2-.) from alveolar macrophages exposed to asbestiform and nonfibrous particles.

Hansen, K., & Mossman, B. T. (1987) · PubMed · Cited by 227 · see citing works

Differences between carbon nanofibers produced using Fe and Ni catalysts in a floating catalyst reactor

Martı́n-Gullón, I., Vera, J. R. N., Conesa, J. A., González, J. L., & Merino, C. (2006) · Carbon · doi:10.1016/j.carbon.2005.12.027 · Cited by 217 · see citing works

Cytokines and Particle-Induced Inflammatory Cell Recruitment

Driscoll, K. E., Carter, J. M., Hassenbein, D. G., & Howard, B. W. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.97105s51159 · Cited by 209 · see citing works

Extrapulmonary transport of MWCNT following inhalation exposure

Mercer, R. R., Scabilloni, J. F., Hubbs, A. F., Wang, L., Battelli, L. A., McKinney, W., Castranova, V., & Porter, D. W. (2013) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-10-38 · Cited by 207 · see citing works

Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes

Mercer, R. R., Scabilloni, J. F., Hubbs, A. F., Battelli, L. A., McKinney, W., Friend, S. A., Wolfarth, M. G., Andrew, M. E., Castranova, V., & Porter, D. W. (2013) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-10-33 · Cited by 206 · see citing works

Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens

Villa, C. H., Dao, T., Ahearn, I. M., Fehrenbacher, N., Casey, E. R., Rey, D. A., Korontsvit, T., Zakhaleva, V., Batt, C. A., Philips, M. R., et al. (2011) · ACS Nano · doi:10.1021/nn200182x · Cited by 205 · see citing works

Biodegradation of Single‐Walled Carbon Nanotubes by Eosinophil Peroxidase

Andón, F. T., Kapralov, A. A., Yanamala, N. V. K., Feng, W., Baygan, A., Chambers, B. J., Hultenby, K. R., Ye, F., Toprak, M. S., Brandner, B. D., et al. (2013) · Small · doi:10.1002/smll.201202508 · Cited by 195 · see citing works

Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes

Porter, D. W., Hubbs, A. F., Chen, B. T., McKinney, W., Mercer, R. R., Wolfarth, M. G., Battelli, L. A., Wu, N., Sriram, K., Leonard, S. S., et al. (2012) · Nanotoxicology · doi:10.3109/17435390.2012.719649 · Cited by 193 · see citing works

Binding of an Anti-Fullerene IgG Monoclonal Antibody to Single Wall Carbon Nanotubes

Erlanger, B. F., Chen, B.-X., Zhu, M. H., & Brus, L. E. (2001) · Nano Letters · doi:10.1021/nl015570r · Cited by 192 · see citing works

An introduction to the short-term toxicology of respirable industrial fibres

Donaldson, K., & Tran, C. L. (2004) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.06.011 · Cited by 189 · see citing works

Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways

Müller, L. L., Riediker, M., Wick, P., Mohr, M., Gehr, P., & Rothen‐Rutishauser, B. (2009) · Journal of The Royal Society Interface · doi:10.1098/rsif.2009.0161.focus · Cited by 189 · see citing works

Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos?

Sanchez, V. C., Pietruska, J. R., Miselis, N. R., Hurt, R. H., & Kane, A. B. (2009) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.41 · Cited by 186 · see citing works

Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity

Zhao, D., Alizadeh, D., Zhang, L., Liu, W., Farrukh, O., Manuel, E. R., Diamond, D. J., & Badie, B. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2444 · Cited by 181 · see citing works

Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

Shvedova, A. A., Kapralov, A. A., Feng, W. H., Kisin, E. R., Murray, A. R., Mercer, R. R., Croix, C. M. S., Lang, M. A., Watkins, S. C., Konduru, N. V., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030923 · Cited by 173 · see citing works

Biodurability of single-walled carbon nanotubes depends on surface functionalization

Liu, X., Hurt, R. H., & Kane, A. B. (2010) · Carbon · doi:10.1016/j.carbon.2010.02.002 · Cited by 169 · see citing works

Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

Murray, A. R., Kisin, E. R., Tkach, A. V., Yanamala, N. V. K., Mercer, R. R., Young, S., Fadeel, B., Kagan, V. E., & Shvedova, A. A. (2012) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-9-10 · Cited by 164 · see citing works

Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice

Shvedova, A. A., Kisin, E. R., Murray, A. R., Gorelik, O., Arepalli, S., Castranova, V., Young, S.-H., Gao, F., Tyurina, Y. Y., Oury, T. D., et al. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.03.018 · Cited by 163 · see citing works

Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

Inoue, K., Koike, E., Yanagisawa, R., Hirano, S., Nishikawa, M., & Takano, H. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.04.003 · Cited by 161 · see citing works

A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro

Buerki‐Thurnherr, T., Brandenberger, C., Fischer, K., Diener, L., Manser, P., Maeder-Althaus, X., Kaiser, J., Krug, H. F., Rothen‐Rutishauser, B., & Wick, P. (2010) · Toxicology Letters · doi:10.1016/j.toxlet.2010.11.012 · Cited by 155 · see citing works

Inflammasome-IL-1-Th17 response in allergic lung inflammation

Besnard, A., Togbe, D., Couillin, I., Tan, Z., Zheng, S. G., Erard, F., Bert, M. L., Quesniaux, V. F. J., & Ryffel, B. (2011) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjr042 · Cited by 153 · see citing works

Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?

Kisin, E. R., Murray, A. R., Sargent, L. M., Lowry, D. T., Chirila, M. M., Siegrist, K. J., Schwegler‐Berry, D., Leonard, S. S., Castranova, V., Fadeel, B., et al. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.02.001 · Cited by 151 · see citing works

Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles

Líbalová, H., Uhlířová, K., Kléma, J., Machala, M., Šrám, R. J., Cigánek, M., & Topinka, J. (2012) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-9-1 · Cited by 149 · see citing works

Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation

Park, E., Cho, W., Jeong, J., Yi, J., Choi, K., & Park, K. (2009) · Toxicology · doi:10.1016/j.tox.2009.02.009 · Cited by 146 · see citing works

Single-Walled Carbon Nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In Situ

Mangum, J. B., Turpin, E. A., Antao-Menezes, A., Cesta, M. F., Bermudez, E., & Bonner, J. C. (2006) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-3-15 · Cited by 143 · see citing works

Adsorption and Desorption of Phenanthrene on Carbon Nanotubes in Simulated Gastrointestinal Fluids

Wang, Z., Zhao, J. L., Song, L., Mashayekhi, H., Chefetz, B., & Xing, B. (2011) · Environmental Science & Technology · doi:10.1021/es200790x · Cited by 142 · see citing works

Carbon Nanotubes Conjugated to Tumor Lysate Protein Enhance the Efficacy of an Antitumor Immunotherapy

Meng, J., Meng, J., Duan, J., Kong, H., Li, L., Wang, C., Xie, S., Chen, S., Gu, N., Xu, H., et al. (2008) · Small · doi:10.1002/smll.200701059 · Cited by 138 · see citing works

Cytotoxicity Evaluation of Oxidized Single-Walled Carbon Nanotubes and Graphene Oxide on Human Hepatoma HepG2 cells: An iTRAQ-Coupled 2D LC-MS/MS Proteome Analysis

Yuan, J., Gao, H., Sui, J., Duan, H., Chen, W. N., & Ching, C. B. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr332 · Cited by 138 · see citing works

Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells

Palomäki, J., Karisola, P., Pylkkänen, L., Savolainen, K., & Alenius, H. T. (2009) · Toxicology · doi:10.1016/j.tox.2009.10.034 · Cited by 135 · see citing works

Development of vaccines toward the global control and eradication of foot-and-mouth disease

Rodrı́guez, L. L., & Gay, C. G. (2011) · Expert Review of Vaccines · doi:10.1586/erv.11.4 · Cited by 135 · see citing works

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

Kermanizadeh, A., Gaiser, B. K., Hutchison, G. R., & Stone, V. (2012) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-9-28 · Cited by 135 · see citing works

Biological Behavior of Hat-Stacked Carbon Nanofibers in the Subcutaneous Tissue in Rats

Yokoyama, A., Sato, Y., Nodasaka, Y., Yamamoto, S., Ḱawasaki, T., Shindoh, M., Kohgo, T., Akasaka, T., Uo, M., Watari, F., et al. (2004) · Nano Letters · doi:10.1021/nl0484752 · Cited by 134 · see citing works

Comparison of Nanotube–Protein Corona Composition in Cell Culture Media

Shannahan, J. H., Brown, J. M., Chen, R., Ke, P. C., Lai, X., Mitra, S., & Witzmann, F. A. (2013) · Small · doi:10.1002/smll.201202243 · Cited by 133 · see citing works

Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies

Wang, L., Castranova, V., Mishra, A., Chen, B. T., Mercer, R. R., Schwegler‐Berry, D., & Rojanasakul, Y. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-31 · Cited by 130 · see citing works

Functionalized carbon nanotubes as immunomodulator systems

Pescatori, M., Bedognetti, D., Venturelli, E., Ménard‐Moyon, C., Bernardini, C., Muresu, E., Piana, A. F., Maida, G., Manetti, R., Sgarrella, F., et al. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.02.052 · Cited by 128 · see citing works

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

Meunier, É., Coste, A., Olagnier, D. P., Authier, H., Lefèvre, L., Dardenne, C., Bernad, J., Béraud, M., Emmanuel Flahaut, B., & Pipy, B. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.11.004 · Cited by 126 · see citing works

In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers

Kermanizadeh, A., Pojana, G., Gaiser, B. K., Birkedal, R. K., Bilaničová, D., Wallin, H., Jensen, K. A., Sellergren, B., Hutchison, G. R., Marcomini, A., et al. (2012) · Nanotoxicology · doi:10.3109/17435390.2011.653416 · Cited by 124 · see citing works

Single-Walled Carbon Nanotube Surface Control of Complement Recognition and Activation

Andersen, A. J., Robinson, J. T., Dai, H., Hunter, A. C., Andresen, T. L., & Moghimi, S. M. (2013) · ACS Nano · doi:10.1021/nn3055175 · Cited by 116 · see citing works

Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells

Hirano, S., Fujitani, Y., Furuyama, A., & Kanno, S. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.08.019 · Cited by 107 · see citing works

Investigating the effects of functionalized carbon nanotubes on reproduction and development in Drosophila melanogaster and CD-1 mice

Philbrook, N. A., Walker, V. K., Afrooz, A. R. M. N., Saleh, N. B., & Winn, L. M. (2011) · Reproductive Toxicology · doi:10.1016/j.reprotox.2011.09.002 · Cited by 106 · see citing works

Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes

Shvedova, A. A., Kisin, E. R., Murray, A. R., Kommineni, C., Castranova, V., Fadeel, B., & Kagan, V. E. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.04.018 · Cited by 106 · see citing works

Testing of Fibrous Particles: Short-Term Assays and Strategies: Report of an ILSI Risk Science Institute Working Group

Bernstein, D., Castranova, V., Donaldson, K., Fubini, B., Hadley, J., Hesterberg, T., Kane, A., Lai, D., McConnell, E. E., Muhle, H., et al. (2005) · Inhalation Toxicology · doi:10.1080/08958370591001121 · Cited by 103 · see citing works

Involvement of intracellular Ca2+ in oxidant‐induced NF‐κB activation

Sen, C. K., Roy, S., & Packer, L. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00346-8 · Cited by 102 · see citing works

Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes

Cesta, M. F., Ryman-Rasmussen, J. P., Wallace, D. G., Masinde, T., Hurlburt, G., Taylor-Just, A. J., & Bonner, J. C. (2009) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2009-0113oc · Cited by 100 · see citing works

Biological response and morphological assessment of individually dispersed multi-wall carbon nanotubes in the lung after intratracheal instillation in rats

Kobayashi, N., Naya, M., Ema, M., Endoh, S., Maru, J., Mizuno, K., & Nakanishi, J. (2010) · Toxicology · doi:10.1016/j.tox.2010.07.021 · Cited by 98 · see citing works

Single-walled carbon nanotube induction of rat aortic endothelial cell apoptosis: Reactive oxygen species are involved in the mitochondrial pathway

Cheng, W., Lin, Z., Wei, B.-F., Zeng, Q., Han, B., Wei, C., Xian-jun, F., Hu, C., Liu, L.-H., Huang, J., et al. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2010.12.013 · Cited by 94 · see citing works

Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung

Crouzier, D., Follot, S., Gentilhomme, E., Emmanuel Flahaut, B., Arnaud, R., Dabouis, V., Castellarin, C., & Debouzy, J. C. (2010) · Toxicology · doi:10.1016/j.tox.2010.04.001 · Cited by 94 · see citing works

Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro

Gasser, M., Wick, P., Clift, M. J. D., Blank, F., Diener, L., Yan, B., Gehr, P., Krug, H. F., & Rothen‐Rutishauser, B. (2012) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-9-17 · Cited by 92 · see citing works

An Oral Formulation of Amphotericin B Attached to Functionalized Carbon Nanotubes Is an Effective Treatment for Experimental Visceral Leishmaniasis

Prajapati, V. K., Awasthi, K., Yadav, T. P., Rai, M., Srivastava, O. N., & Sundar, S. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir735 · Cited by 92 · see citing works

Steering Carbon Nanotubes to Scavenger Receptor Recognition by Nanotube Surface Chemistry Modification Partially Alleviates NFκB Activation and Reduces Its Immunotoxicity

Gao, N., Zhang, Q., Mu, Q., Bai, Y., Li, L., Zhou, H., Butch, E. R., Powell, T. B., Snyder, S. E., Jiang, G., et al. (2011) · ACS Nano · doi:10.1021/nn200283g · Cited by 89 · see citing works

Pleural macrophage recruitment and activation in asbestos-induced pleural injury.

Choe, N., Tanaka, S., Xia, W., Hemenway, D. R., Roggli, V. L., & Kagan, E. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.97105s51257 · Cited by 80 · see citing works

Carbon Nanotubes Activate Store-Operated Calcium Entry in Human Blood Platelets

Lacerda, S. H. D. P., Šemberová, J., Holada, K., Šimáková, O., Hudson, S. D., & Šimák, J. (2011) · ACS Nano · doi:10.1021/nn2015369 · Cited by 80 · see citing works

Ex Vivo Impact of Functionalized Carbon Nanotubes on Human Immune Cells

Delogu, L. G., Venturelli, E., Manetti, R., Pinna, G. A., Carru, C., Madeddu, R., Murgia, L., Sgarrella, F., Dumortier, H., & Bianco, A. (2011) · Nanomedicine · doi:10.2217/nnm.11.101 · Cited by 78 · see citing works

Ninety-Day Inhalation Toxicity Study With A Vapor Grown Carbon Nanofiber in Rats

DeLorme, M. P., Muro, Y., Arai, T., Banas, D. A., Frame, S. R., Reed, K. L., & Warheit, D. B. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs172 · Cited by 76 · see citing works

Interactions of single-wall carbon nanotubes with endothelial cells

Albini, A., Mussi, V., Parodi, A., Ventura, A., Principi, E., Tegami, S., Rocchia, M., Francheschi, E., Sogno, I., Cammarota, R., et al. (2009) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2009.08.001 · Cited by 73 · see citing works

Critical role of glass fiber length in TNF-α production and transcription factor activation in macrophages

Ye, J., Shi, X., Jones, W. G., Rojanasakul, Y., Cheng, N., Schwegler‐Berry, D., Baron, P. A., Deye, G. J., Li, C., & Castranova, V. (1999) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1999.276.3.l426 · Cited by 73 · see citing works

A Comparative Study of Different In Vitro Lung Cell Culture Systems to Assess the Most Beneficial Tool for Screening the Potential Adverse Effects of Carbon Nanotubes

Clift, M. J. D., Voss, C., Vanhecke, D., Wick, P., Gehr, P., Schins, R. P. F., Petri‐Fink, A., & Rothen‐Rutishauser, B. (2013) · Toxicological Sciences · doi:10.1093/toxsci/kft216 · Cited by 72 · see citing works

Lack of genotoxicity of carbon nanotubes in a pilot study.

Szendi, K., & Varga, C. (2008) · PubMed · Cited by 71 · see citing works

Subcutaneous injection of water-soluble multi-walled carbon nanotubes in tumor-bearing mice boosts the host immune activity

Meng, J., Yang, M. G., Jia, F., Kong, H., Zhang, W., Wang, C., Xing, J., Xie, S., & Xu, H. (2010) · Nanotechnology · doi:10.1088/0957-4484/21/14/145104 · Cited by 67 · see citing works

Immunological profile of a Plasmodium vivax AMA-1 N-terminus peptide-carbon nanotube conjugate in an infected Plasmodium berghei mouse model

Yandar, N., Pastorin, G., Prato, M., Bianco, A., Patarroyo, M. E., & Lozano, J. M. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.08.014 · Cited by 66 · see citing works

Carbon nanotubes as a novel tool for vaccination against infectious diseases and cancer

Gottardi, R., & Douradinha, B. G. (2013) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-11-30 · Cited by 66 · see citing works

Improved osteoblast viability in the presence of smaller nanometre dimensioned carbon fibres

Price, R. L., Haberstroh, K. M., & Webster, T. J. (2004) · Nanotechnology · doi:10.1088/0957-4484/15/8/004 · Cited by 62 · see citing works

Complement activation by carbon nanotubes

Rybak-Smith, M. J., & Sim, R. B. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.05.012 · Cited by 61 · see citing works

Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes

Meng, J., Yang, M. G., Jia, F., Xu, Z., Kong, H., & Xu, H. (2010) · Nanotoxicology · doi:10.3109/17435390.2010.523483 · Cited by 61 · see citing works

Perspectives on carbon nanotube-mediated adverse immune effects

Andersen, A. J., Wibroe, P. P., & Moghimi, S. M. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.05.005 · Cited by 59 · see citing works

Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients

LAVERNY, G., Casset, A., Purohit, A., Schaeffer, E., Spiegelhalter, C., Frederic de, B. L. A. Y., & Pons, F. (2012) · Toxicology Letters · doi:10.1016/j.toxlet.2012.12.008 · Cited by 58 · see citing works

Mechanisms of Macrophage Accumulation in the Lungs of Asbestos-Exposed Subjects

Spurzem, J. R., Saltini, C., Rom, W. N., WINCHESTER, R. J., & Crystal, R. G. (1987) · American Review of Respiratory Disease · doi:10.1164/ajrccm/136.2.276 · Cited by 57 · see citing works

Maternal exposure to multi‐wall carbon nanotubes does not induce embryo–fetal developmental toxicity in rats

Lim, J.-H., Kim, S., Shin, I., Park, N.-H., Moon, C., Kang, S. S., Kim, S., Park, S., & Kim, J. (2011) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20283 · Cited by 57 · see citing works

Proteins of the Innate Immune System Crystallize on Carbon Nanotubes but Are Not Activated

Ling, W. L., Bı́ró, A., Bally, I., Tacnet‐Delorme, P., Deniaud, A., Doris, E., Frachet, P., Schoehn, G., Pebay‐Peyroula, E., & Arlaud, G. J. (2011) · ACS Nano · doi:10.1021/nn102400w · Cited by 57 · see citing works

Carbon Nanotube Scaffolds Instruct Human Dendritic Cells: Modulating Immune Responses by Contacts at the Nanoscale

Aldinucci, A., Turco, A., Biagioli, T., Toma, F. M., Bani, D., Guasti, D., Manuelli, C., Rizzetto, L., Cavalieri, D., Massacesi, L., et al. (2013) · Nano Letters · doi:10.1021/nl403396e · Cited by 56 · see citing works

System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses

Snyder‐Talkington, B. N., Dymacek, J., Porter, D. W., Wolfarth, M. G., Mercer, R. R., Pacurari, M., Denvir, J., Castranova, V., Qian, Y. R., & Guo, N. L. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.06.026 · Cited by 56 · see citing works

The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4

BROWN, D., Hutchison, L., Donaldson, K., MACKENZIE, S., Dick, C. A. J., & Stone, V. (2006) · Toxicology Letters · doi:10.1016/j.toxlet.2006.10.016 · Cited by 55 · see citing works

PEGylated single-walled carbon nanotubes activate neutrophils to increase production of hypochlorous acid, the oxidant capable of degrading nanotubes

Vlasova, I. I., Vakhrusheva, T. V., Av, S., Kostevich, V. A., Gusev, A. A., Гусев, С. А., Melnikova, V. I., & Lobach, A. S. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2012.07.027 · Cited by 55 · see citing works

Differential release of superoxide anions by macrophages treated with long and short fibre amosite asbestos is a consequence of differential affinity for opsonin.

Hill, I. M., Beswick, P. H., & Donaldson, K. (1995) · Occupational and Environmental Medicine · doi:10.1136/oem.52.2.92 · Cited by 55 · see citing works

Relating the physicochemical characteristics and dispersion of multiwalled carbon nanotubes in different suspension media to their oxidative reactivityin vitroand inflammationin vivo

Rothen‐Rutishauser, B., Brown, D. M., Boyles, M. S. P., Kinloch, I. A., Windle, A. H., Gehr, P., & Stone, V. (2010) · Nanotoxicology · doi:10.3109/17435390.2010.489161 · Cited by 54 · see citing works

Immunological and cytotoxicological characterization of tuberculin purified protein derivative (PPD) conjugated to single-walled carbon nanotubes

Zeinali, M., Jamalan, M., Ardestani, S. K., & Mosaveri, N. (2009) · Immunology Letters · doi:10.1016/j.imlet.2009.07.012 · Cited by 53 · see citing works

Long-term biopersistence of tangled oxidized carbon nanotubes inside and outside macrophages in rat subcutaneous tissue

Sato, Y., Yokoyama, A., Nodasaka, Y., Kohgo, T., Motomiya, K., Matsumoto, H., Nakazawa, E., Numata, T., Zhang, M., Yudasaka, M., et al. (2013) · Scientific Reports · doi:10.1038/srep02516 · Cited by 53 · see citing works

Carbon nanotube-protein carriers enhance size-dependent self-adjuvant antibody response to haptens

Parra, J., Abad‐Somovilla, A., Mercader, J. V., Taton, T. A., & Abad‐Fuentes, A. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.05.019 · Cited by 51 · see citing works

Carbon Nanotubes Enhance Cytotoxicity Mediated by Human Lymphocytes In Vitro

Sun, Z., Liu, Z., Meng, J., Meng, J., Duan, J., Xie, S., Lu, X., Zhu, Z., Wang, C., Chen, S., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021073 · Cited by 51 · see citing works

Differential Responses of Rat Alveolar and Peritoneal Macrophages to Man-Made Vitreous Fibers in Vitro

Dörger, M., Münzing, S., Allmeling, A.-M., Meßmer, K., & Krombach, F. (2001) · Environmental Research · doi:10.1006/enrs.2001.4234 · Cited by 49 · see citing works

Handbook of Immunological Properties of Engineered Nanomaterials

Dobrovolskaia, M. A., & McNeil, S. E. (2012) · Frontiers in nanobiomedical research · doi:10.1142/8390 · Cited by 45 · see citing works

Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

Yamaguchi, A., Fujitani, T., Ohyama, K.-I., Nakae, D., Hirose, A., Nishimura, T., & Ogata, A. (2012) · The Journal of Toxicological Sciences · doi:10.2131/jts.37.177 · Cited by 40 · see citing works

Transient oxidative stress and inflammation after intraperitoneal administration of multiwalled carbon nanotubes functionalized with single strand DNA in rats

Clichici, S. V., Biris, A. R., Tăbăran, F., & Filip, G. A. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2012.01.004 · Cited by 38 · see citing works

Evaluation of the direct and indirect response of blood leukocytes to carbon nanotubes (CNTs)

Medepalli, K., Alphenaar, B., Raj, A. B., & Sethu, P. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.04.002 · Cited by 38 · see citing works

Nuclear Translocation of Nrf2 and Expression of Antioxidant Defence Genes in THP-1 Cells Exposed to Carbon Nanotubes

Brown, D. M., Donaldson, K., & Stone, V. (2010) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2010.1117 · Cited by 35 · see citing works

Up-regulation of T lymphocyte and antibody production by inflammatory cytokines released by macrophage exposure to multi-walled carbon nanotubes

Grecco, A. C. P., de Paula, R. F. O., Mizutani, E., Sartorelli, J. C., Milani, A. M., Longhini, A. L. F., de Oliveira, E. C., Pradella, F. M., Silva, V. D. R., Moraes, A. S., et al. (2011) · Nanotechnology · doi:10.1088/0957-4484/22/26/265103 · Cited by 32 · see citing works

No toxicological effects on acute and repeated oral gavage doses of single-wall or multi-wall carbon nanotube in rats

Matsumoto, M., Serizawa, H., Sunaga, M., Kato, H., Takahashi, M., Hirata‐Koizumi, M., Ono, A., Kamata, E., & Hirose, A. (2012) · The Journal of Toxicological Sciences · doi:10.2131/jts.37.463 · Cited by 29 · see citing works

Pleural Macrophage Recruitment and Activation in Asbestos-Induced Pleural Injury

Choe, N., Tanaka, S., Xia, W., Hemenway, D. R., Roggli, V. L., & Kagan, E. (1997) · Environmental Health Perspectives · doi:10.2307/3433543 · Cited by 29 · see citing works

Nanoparticles and the immune system : safety and effects

Boraschi, D., & Duschl, A. (2014) · Cited by 28 · see citing works

An In Vitro Evaluation of the Biological Effects of Carbon Nanotube-Coated Dental Zirconia

Kou, W., Akasaka, T., Watari, F., & Sjögren, G. (2013) · ISRN Dentistry · doi:10.1155/2013/296727 · Cited by 26 · see citing works

Effect of Functionalization of Carbon Nanotubes with Psychosine on Complement Activation and Protein Adsorption

Rybak-Smith, M. J., Tripisciano, C., Borowiak‐Palen, E., Lamprecht, C., & Sim, R. B. (2011) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2011.1347 · Cited by 26 · see citing works

Interactions of polydispersed single-walled carbon nanotubes with T cells resulting in downregulation of allogeneic CTL responsesin vitroandin vivo

Alam, A., Sachar, S., Puri, N., & Saxena, R. K. (2012) · Nanotoxicology · doi:10.3109/17435390.2012.739666 · Cited by 25 · see citing works

Immunomodulatory effects of carbon nanotubes functionalized with a Toll-like receptor 7 agonist on human dendritic cells

Čolić, M. J., Džopalić, T., Tomić, S., Rajković, J., Rudolf, R., Vuković, G. D., Marinković, А., & Uskoković, P. S. (2013) · Carbon · doi:10.1016/j.carbon.2013.09.090 · Cited by 25 · see citing works

Preparation and Theophylline Delivery Applications of Novel PMAA/MWCNT-COOH Nanohybrid Hydrogels

Chang-hu, Z., Luo, Y., Chen, Y., Wei, Q.-B., & Fan, L. (2009) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856209x444466 · Cited by 24 · see citing works

Carbon Nanofibers Have IgE Adjuvant Capacity but Are Less Potent Than Nanotubes in Promoting Allergic Airway Responses

Nygaard, U. C., Samuelsen, M., Marioara, C. D., & Løvik, M. (2013) · BioMed Research International · doi:10.1155/2013/476010 · Cited by 18 · see citing works

Distribution And Persistence Of Pleural Penetrations By Multi-Walled Carbon Nanotubes

Mercer, R. R., Hubbs, A. F., Scabilloni, J. F., Wang, L., Castranova, V., & Porter, D. W. (2010) · doi:10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3102 · Cited by 15 · see citing works

Uptake and Silica and Carbon Nanotubes by Human Macrophages/Monocytes Induces Activation of Fibroblasts in vitro — Potential Implication for Pathogenesis of Inflammation and Fibrotic Diseases

Guo, X., Jagannath, C., Espitia, M. G., & Zhou, X. (2012) · International Journal of Immunopathology and Pharmacology · doi:10.1177/039463201202500317 · Cited by 14 · see citing works

Biodistribution of Aqueous Suspensions of Carbon Nanotubes in Mice and Their Biocompatibility

Abe, S., Itoh, S., Hayashi, D., Kobayashi, T., Kiba, T., Akasaka, T., Uo, M., Yawaka, Y., Sato, S., Watari, F., et al. (2012) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2012.5391 · Cited by 8 · see citing works

Immune System

Boraschi, D., & Duschl, A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-386940-1.00010-6 · Cited by 7 · see citing works

Oxidative Stress-Mediated Pro-Inflammatory Responses in Lung Epithelial Cells Exposed to Multi-Walled Carbon Nanotubes

Han, M. S., Ye, S., Wen, W., & Zhang, Q. (2010) · International Conference on Bioinformatics and Biomedical Engineering · doi:10.1109/icbbe.2010.5516569 · Cited by 3 · see citing works

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Kuempel, E. D., Jaurand, M., Möller, P., Morimoto, Y., Kobayashi, N., Pinkerton, K. E., Sargent, L. M., Vermeulen, R. C. H., Fubini, B., & Kane, A. B. (2016) · Critical Reviews in Toxicology · doi:10.1080/10408444.2016.1206061 · Cited by 106 · see citing works

A Data Fusion Pipeline for Generating and Enriching Adverse Outcome Pathway Descriptions

Nymark, P. E. H., Rieswijk, L., Ehrhart, F., Jeliazkova, N., Tsiliki, G., Sarimveis, H., Evelo, C. T., Hongisto, V., Kohonen, P. J., Willighagen, E., et al. (2017) · Toxicological Sciences · doi:10.1093/toxsci/kfx252 · Cited by 61 · see citing works

Neurobehavioral toxicity of carbon nanotubes in mice

Gholamine, B., Karimi, I., Salimi, A., Mazdarani, P., & Becker, L. A. (2016) · Toxicology and Industrial Health · doi:10.1177/0748233716644381 · Cited by 51 · see citing works

Effect of pristine and functionalized multiwalled carbon nanotubes on rat renal cortex

Gazia, M. A., & El‐Magd, M. A. (2018) · Acta Histochemica · doi:10.1016/j.acthis.2018.12.005 · Cited by 51 · see citing works

Gadolinium‐containing carbon nanomaterials for magnetic resonance imaging: Trends and challenges

Rodríguez‐Galván, A., Rivera, M., García‐López, P., Medina, L. A., & Basiuk, V. A. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15065 · Cited by 39 · see citing works

Nanomaterials in the Context of Type 2 Immune Responses—Fears and Potentials

Himly, M., Mills-Goodlet, R., Geppert, M., & Duschl, A. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00471 · Cited by 21 · see citing works

Tailoring the dynamic nanocomposite hydrogels through surface-functionalized nanomaterials and interfacial crosslinking chemistry toward multifunctional biomedical and engineering applications

Su, Y., Chen, G.-Y., Lai, Y.-J., Song, G.-Z., Wu, T., & Yeh, Y. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00975h · Cited by 19 · see citing works

Measurement of Flexural Rigidity of Multi-Walled Carbon Nanotubes by Dynamic Scanning Electron Microscopy

Fortini, R., Meyer-Plath, A., Kehren, D., Gernert, U., Jácome, L. A., & Sturm, H. (2020) · Fibers · doi:10.3390/fib8050031 · Cited by 18 · see citing works

Protein-Free Hapten-Carbon Nanotube Constructs Induce the Secondary Immune Response

Ceballos-Alcantarilla, E., Abad‐Somovilla, A., Agulló, C., Abad‐Fuentes, A., & Mercader, J. V. (2017) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00653 · Cited by 9 · see citing works

Mapping differential cellular protein response of mouse alveolar epithelial cells to multi-walled carbon nanotubes as a function of atomic layer deposition coating

Hilton, G. M., Taylor-Just, A. J., Hussain, S., Dandley, E. C., Griffith, E. H., Garantziotis, S., Parsons, G. N., Bonner, J. C., & Bereman, M. S. (2017) · Nanotoxicology · doi:10.1080/17435390.2017.1299888 · Cited by 7 · see citing works

Application of Raman Spectroscopy for Studying the Mechanisms of Neutrophil Activation by Carbon Nanotubes

Golubewa, L., Kulahava, T. A., Leonik, Y. S., Shuba, M. V., & Семенкова, Г. Н. (2021) · Journal of Applied Spectroscopy · doi:10.1007/s10812-021-01143-1 · Cited by 6 · see citing works

Muscle cytotoxicity and immuno-reactivity analysis of the porous carbon nanospheres fabricated by high temperature calcination

Huang, J.-W., Jian, X., Xu, M., Wang, H., Liao, Z., Lan, H., Wang, L., Hu, J., Yu, Q., & Liao, H. (2022) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2022.102632 · Cited by 3 · see citing works

Editorial: Exploring impacts of combined exposures to particles and chemicals on immune reactions across living organisms

Boraschi, D., Duschl, A., Lynch, I., & Stoeger, T. (2023) · Frontiers in Toxicology · doi:10.3389/ftox.2023.1148374 · Cited by 3 · see citing works

Macrophages bend long fibres with flexural rigidity lower than 3 mN·nm2 to avoid frustrated phagocytosis

Broßell, D., Meyer-Plath, A., Gräb, O., Heunisch, E., Kämpf, K., Haase, A., & Wiemann, M. (2026) · Particle and Fibre Toxicology · doi:10.1186/s12989-026-00666-9 · Cited by 2 · see citing works

Experimental approaches to data generation for REACH compliance of multi-walled carbon nanotubes: substance identification

Bohlen, M., Jeon, H. P., Jo, H., & Lee, Y. (2026) · Environmental Science Nano · doi:10.1039/d5en01017a · Cited by 2 · see citing works

Nanofibers: Friend or Foe?

Petri‐Fink, A., Rothen‐Rutishauser, B., & Clift, M. J. D. (2016) · Fibers · doi:10.3390/fib4030025 · Cited by 2 · see citing works

Selective Enrichment of Fibrous Fragments Formed from Milled Carbon Fibers by Means of Gravitational Settling in a Liquid

y Fischer, N. R., Kämpf, K., Peters, T., Dziurowitz, N., Thim, C., Wenzlaff, D., Meyer‐Plath, A., & Bäger, D. (2025) · Fibers · doi:10.3390/fib13060069 · Cited by 1 · see citing works

Proteomic Investigation of Various Methods used for Carbon Nanotube Exposure.

Hilton, G. M. (2017) · NCSU Libraries Repository (North Carolina State University Libraries)

Potential hazardous effects of carbon nanotubes and carbon nanofibers

Ćwirzeń, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85856-4.00008-x

Nanofibres: Friend or Foe?

Fink, A., Rothen‐Rutishauser, B., & Clift, M. (2016) · MDPI eBooks · doi:10.3390/books978-3-03842-279-2

Új környezettoxikológia – megalapozó javaslatok

Varga, C. (2022) · Egeszsegtudomany · doi:10.29179/egtud.2022.3-4.77-118

Safety Assessment of Nanotechnology Products

Kidd, J., & Stapleton, P. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00183-2

Signaling Pathways Implicated in Carbon Nanotube-Induced Lung Inflammation

Dong, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.552613 · Cited by 48 · see citing works

Carbon nanotubes provoke inflammation by inducing the pro-inflammatory genes IL-1β and IL-6

Qu, C., Wang, L., He, J., Tan, J., Liu, W., Zhang, S., Zhang, C., Wang, Z., Jiao, S., Liu, S., et al. (2011) · Gene · doi:10.1016/j.gene.2011.11.046 · Cited by 40 · see citing works

Carbon nanotubes provoke inflammation by inducing the pro-inflammatory genes IL-1 beta and IL-6

Qu, C., Wang, L., He, J., Tan, J., Liu, W., Zhang, S., Zhang, C., Wang, Z., Jiao, S., Liu, S., et al. (2012) · Research Center for Eco-Environmental Sciences OpenIR (Chinese Academy of Sciences)

Mechanisms Underlying the Fibrogenic Responses of Carbon Nanotubes

Manke, A., Rojanasakul, L. W., & Rojanasakul, Y. (2018) · Advances in molecular toxicology · doi:10.1016/b978-0-444-64199-1.00003-8 · Cited by 2 · see citing works

Inhalative Gefahren der Zukunft : Carbon Nanotubes im ex-vivo Modell

Merkelbach, J. J. (2025) · RWTH Publications (RWTH Aachen)