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Cited by 48Body Composition Measurement TechniquesBone health and osteoporosis researchHIV-related health complications and treatments

Comparison of Bioelectrical Impedance Analysis and Dual Energy X-ray Absorptiometry for Total and Segmental Bone Mineral Content with a Three-Compartment Model

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Liao, Yu-San, Li, Hung-Chou, Lu, Hsueh-Kuan, Lai, Chung-Liang, Wang, Yue-Sheng, Hsieh, Kuen-Chang·2020·International Journal of Environmental Research and Public Health
DOI 10.3390/ijerph17072595PMC PMC7177846
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Abstract

Modern bioelectrical impedance analysis (BIA) provides a wide range of body composition estimates such as fat mass (FM), lean body mass (LBM), and body water, using specific algorithms. Assuming that the fat free mass (FFM) and LBM can be accurately estimated by the 8-electrode BIA analyzer (BIA8MF; InBody230, Biospace), the bone mineral content (BMC) may be calculated by subtracting the LBM from the FFM estimates based on the three-compartment (3C) model. In this cross-sectional study, 239 healthy Taiwanese adults (106 male and 133 female) aged 20–45 years were recruited for BIA and dual-energy X-ray absorptiometry (DXA) measurements of the whole body and body segments, with DXA as the reference. The results showed a high correlation between BIA8MF and DXA in estimating total and segmental LBM, FM and percentage body fat (r = 0.909–0.986, 0.757–0.964, and 0.837–0.936, respectively). For BMC estimates, moderate to high correlations (r = 0.425–0.829) between the two methods were noted. The percentage errors and pure errors for BMC estimates between the methods ranged from 33.9% to 93.0% and from 0.159 kg to 0.969 kg, respectively. This study validated that BIA8MF can accurately assesses LBM, FM and body fat percentage (BF%). However, the estimation of segmental BMC based on the difference between FFM and LBM in body segments may not be reliable by BIA8MF.

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  • DXA has become the preferred method for assessing body composition, with a notable advantage being that it provides a multi-compartment assessment that includes bone.

    “DXA has become the preferred method for assessing body composition, with a notable advantage being that it provides a multi-compartment assessment that includes bone [68,69].”

    From The Utility of Body Composition Assessment in Nutrition and Clinical Practice: An Overview of Current Methodology (2021) · cites this paper as [68]

    The Introduction describes DXA as a three-compartment method that partitions the body into fat, lean, and bone, and says it is commonly used as a reference method. It does not establish that DXA is the preferred method for body-composition assessment generally, rather than a reference method in particular contexts. (LLM, conf=0.83)

    Experimental — accuracy not yet measured

  • With DXA, practitioners can quantify FM, bone mineral content, and non-bone, fat-free tissue mass, thereby reducing the assumptions being relied on with SKF, ADP, and HW methods.

    “With DXA, practitioners can quantify FM, bone mineral content, and non-bone, fat-free tissue mass, thereby reducing the assumptions being relied on with SKF, ADP, and HW methods [68].”

    From The Utility of Body Composition Assessment in Nutrition and Clinical Practice: An Overview of Current Methodology (2021) · cites this paper as [68]

    The Introduction (page not provided) describes DXA as partitioning the body into fat, lean, and bone components, and Methods §2.3 reports DXA measurements of fat mass, lean body mass, and bone mineral content. The paper does not establish that DXA reduces reliance on assumptions compared with skinfold, air-displacement plethysmography, or hydrostatic-weighing methods; it says DXA itself uses a soft-tissue assumption. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

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Cited by

Sorted by citations

Authors
Liao, Y.-S., Li, H.-C., Lu, H.-K., Lai, C.-L., Wang, Y.-S., & Hsieh, K.-C.
Affiliations
  • Chang Gung University of Science and Technology (TW)
  • Chang Gung Memorial Hospital (TW)
  • National Taiwan University of Sport (TW)
  • Asia University (TW)
  • Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi613, Taiwan
  • National Chin-Yi University of Technology (TW)
Corresponding author
Hsieh, Kuen-Chang
ORCID
Venue
International Journal of Environmental Research and Public Health
Publisher
MDPI AG
Published
2020-04-10
Volume
17
Issue
7
Pages
2595
ISSN
1660-4601 (ISSN-L)
DOI
10.3390/ijerph17072595
PMC
PMC7177846
OpenAlex
W3015444662
Cited by
48
References
4
Citations by year
2026: 2 · 2025: 10 · 2024: 7 · 2023: 6 · 2022: 9 · 2021: 11 · 2020: 3
FWCI
4.36
Type
journal article
Language
en
Open access
Licence
Locations
  • International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
Chang Gung Medical Foundation (CMRPG6D0271)
Topics
  • Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
  • Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
Keywords
bioelectrical impedance analysis, dual-energy X-ray absorptiometry, bone mineral content, three-compartment model, fat-free mass, lean body mass, fat mass, body fat percentage, body composition assessment, method comparison
MeSH terms
Adipose Tissue, Adult, Body Composition, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Taiwan, Absorptiometry, Photon, Bone Density, Electric Impedance

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