Psychological Distress in South African Healthcare Workers Early in the COVID-19 Pandemic: An Analysis of Associations and Mitigating Factors
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Abstract
While the global COVID-19 pandemic has been widely acknowledged to affect the mental health of health care workers (HCWs), attention to measures that protect those on the front lines of health outbreak response has been limited. In this cross-sectional study, we examine workplace contextual factors associated with how psychological distress was experienced in a South African setting where a severe first wave was being experienced with the objective of identifying factors that can protect against HCWs experiencing negative impacts. Consistent with mounting literature on mental health effects, we found a high degree of psychological distress (57.4% above the General Health Questionnaire cut-off value) and a strong association between perceived risks associated with the presence of COVID-19 in the healthcare workplace and psychological distress (adjusted OR = 2.35, p < 0.01). Our research indicates that both training (adjusted OR 0.41, 95% CI 0.21–0.81) and the reported presence of supportive workplace relationships (adjusted OR 0.52, 95% CI 0.27–0.97) were associated with positive outcomes. This evidence that workplace resilience can be reinforced to better prepare for the onset of similar outbreaks in the future suggests that pursuit of further research into specific interventions to improve resilience is well merited.
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In South Africa during the COVID-19 pandemic, team cohesion and supportive leadership emerged as particularly effective resilience mechanisms.
“In South Africa during the COVID-19 pandemic, team cohesion and supportive leadership emerged as particularly effective resilience mechanisms (27).”
From Management strategies for healthcare worker burnout in Sub-Saharan Africa: an integrative review (2026) · cites this paper as [27]
The Results (§3.6; page unavailable) report that support from an immediate supervisor was associated with less psychological distress. They say only supervisor support—not support from other sources—showed this association, so the finding does not establish team cohesion as a protective mechanism. Because the study was cross-sectional, it also does not demonstrate that either factor was an effective intervention. (LLM, conf=0.88)
Experimental — accuracy not yet measuredStudies during COVID-19 demonstrated that weak infrastructure and insufficient institutional support intensified distress.
“Studies during COVID-19 similarly demonstrated that weak infrastructure and insufficient institutional support intensified distress (27, 28, 34).”
From Management strategies for healthcare worker burnout in Sub-Saharan Africa: an integrative review (2026) · cites this paper as [27]
The Discussion (page not available) identifies perceived barriers to infection control—including space and manager support—as predictors of psychological distress. The Results (section 3.6, page not available) associate better supervisor support with less distress. But the Limitations (section 4.2) say the cross-sectional study cannot establish cause and effect, so it does not demonstrate that weak infrastructure and insufficient support intensified distress. (LLM, conf=0.86)
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Management strategies for healthcare worker burnout in Sub-Saharan Africa: an integrative review
Khangamwa-Singano, F., Singano, V. H., Kaunda, P., Machongo, R. B., & Nkhoma-Mussa, Y. B. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1779807 · Cited by 1 · see citing works
“The cross-sectional studies by Moses et al. (28), Lee et al. (27), Ledikwe et al. (13), and Kabunga et al. (18),were appraised using the JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies (31).”
Influential
- Authors
- Lee, H.-L., Wilson, K. S., Bernstein, C., Naicker, N., Yassi, A., & Spiegel, J. M.
- Affiliations
- University of British Columbia (CA)
- National Health Laboratory Service (ZA)
- University of the Witwatersrand (ZA)
- Corresponding author
- Yassi, Annalee
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2022-08-07
- Volume
- 19
- Issue
- 15
- Pages
- 9722
- ISSN
- 1660-4601 (ISSN-L)
- PMC
- PMC9368661
- OpenAlex
- W4290515206
- Cited by
- 24
- References
- 9
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 7 · 2023: 12 · 2022: 1
- FWCI
- 5.02
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- cIRcle (University of British Columbia) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- The International Development Research Centre (IDRC) (M20-00559, VS1-175519)
- the Canadian Institutes of Health Research (CIHR) (M20-00559, VS1-175519)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Health Professions › General Health Professions › Healthcare professionals’ stress and burnout
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Burnout
- Keywords
- psychological distress, healthcare workers, COVID-19 pandemic, workplace mental health, risk perception, workplace relationships, resilience, training, South Africa
- MeSH terms
- Psychological Distress, COVID-19, Cross-Sectional Studies, Health Personnel, Humans, South Africa, Pandemics
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