The DOI matches its Crossref record; 222 of the 226 references it cites were found in a registry or an index.
Potential Adverse Effects of Resveratrol: A Literature Review
Open accessAbstract
Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol’s health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive research activity into this compound. Ever since, several pharmacological activities including antioxidant, anti-aging, anti-inflammatory, anti-cancerous, anti-diabetic, cardioprotective, and neuroprotective properties, were attributed to RE. However, results from the available human clinical trials were controversial concerning the protective effects of RE against diseases and their sequelae. The reason for these conflicting findings is varied but differences in the characteristics of the enrolled patients, RE doses used, and duration of RE supplementation were proposed, at least in part, as possible causes. In particular, the optimal RE dosage capable of maximizing its health benefits without raising toxicity issues remains an area of extensive research. In this context, while there is a consistent body of literature on the protective effects of RE against diseases, there are relatively few reports investigating its possible toxicity. Indeed, toxicity and adverse effects were reported following consumption of RE; therefore, extensive future studies on the long-term effects, as well as the in vivo adverse effects, of RE supplementation in humans are needed. Furthermore, data on the interactions of RE when combined with other therapies are still lacking, as well as results related to its absorption and bioavailability in the human body. In this review, we collect and summarize the available literature about RE toxicity and side effects. In this process, we analyze in vitro and in vivo studies that have addressed this stilbenoid. These studies suggest that RE still has an unexplored side. Finally, we discuss the new delivery methods that are being employed to overcome the low bioavailability of RE.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“A high-dose administration of resveratrol in animal experiments showed proinflammatory and cytotoxic effects.”
From Mediterranean Diet as an Antioxidant: The Impact on Metabolic Health and Overall Wellbeing (2021) · cites this paper as [129]
In the citing paper
“In addition, pharmacokinetic interactions have been described, mainly due to CYP450 induction, which may affect the pharmacokinetics of other drugs [129].”
From Mediterranean Diet as an Antioxidant: The Impact on Metabolic Health and Overall Wellbeing (2021) · cites this paper as [129]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Sun, Y., Zhou, Q., Lu, Y.-Y., Zhang, H., Chen, Q., Zhao, M., & Su, S.-B. (2019) · Molecules · doi:10.3390/molecules24061131 · Cited by 174
RetractedFree radicals, metals and antioxidants in oxidative stress-induced cancer
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680
Resveratrol improves health and survival of mice on a high-calorie diet
Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290
Therapeutic potential of resveratrol: the in vivo evidence
Baur, J. A., & Sinclair, D. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2060 · Cited by 3,958
Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress
Cai, H., & Harrison, D. G. (2000) · Circulation Research · doi:10.1161/01.res.87.10.840 · Cited by 3,839
Müller, R. H., Radtke, M., & Wissing, S. A. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00118-7 · Cited by 2,116
HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
Walle, T., Hsieh, F., DeLegge, M. H., Oatis, J. E., & Walle, U. K. (2004) · Drug Metabolism and Disposition · doi:10.1124/dmd.104.000885 · Cited by 1,893
WNT and β-catenin signalling: diseases and therapies
Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1427 · Cited by 1,763
Role of ROS and RNS Sources in Physiological and Pathological Conditions
Meo, S. D., Reed, T. T., Venditti, P., & Víctor, V. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/1245049 · Cited by 1,712
Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Williamson, G., & Manach, C. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.243s · Cited by 1,340
Flagged first, then by citations
4 of the 226 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Takaoka, 1939, Resveratrol, a new phenolic compound, from Veratrum grandiflorum, J. Chem. Soc. Jpn., 60, 1090
- Sotoudehmanesh, 2010, Methotrexate hepatotoxicity in patients with rheumatoid arthritis, Middle East J. Dig. Dis., 2, 104
Cited by
Sorted by citations
Items 201–300 of 716
Iweala, E., Adurosakin, O. E., Dania, O. E., & Ugbogu, E. A. (2023) · Life · doi:10.3390/life13071422 · Cited by 23
Dikalova, A., Ao, M., Tkachuk, L., & Dikalov, S. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00162.2024 · Cited by 23
Weinstock, M. (2025) · Antioxidants · doi:10.3390/antiox14070769 · Cited by 25
Costa, P. S., Ramos, P. S., Ferreira, C., Silva, J. L., El‐Bacha, T., & Fialho, E. (2021) · Nutrition and Cancer · doi:10.1080/01635581.2021.1977834 · Cited by 23
Nowrasteh, G., Zand, A., Raposa, B. L., Szabó, L. G., Tomesz, A., Molnár, R., Kiss, I., Orsós, Z., Gerencsér, G., Gyöngyi, Z., et al. (2023) · Nutrients · doi:10.3390/nu15081867 · Cited by 23
Upadhyay, P., Tyagi, A., Agrawal, S., Kumar, A., & Gupta, S. (2023) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300104 · Cited by 23
Effects and safety of resveratrol supplementation in older adults: A comprehensive systematic review
Yadegar, S., Mohammadi, F., Yadegar, A., Naeini, A. M., Ayati, A., Milan, N., Tayebi, A., Seyedi, S. A., Nabipoorashrafi, S. A., Rabizadeh, S., et al. (2024) · Phytotherapy Research · doi:10.1002/ptr.8171 · Cited by 23
Zhou, M., Niu, H., Cui, D., Huang, G., Li, J., Tian, H., Xu, X.-J., Liang, F., & Chen, R. (2024) · Phytotherapy Research · doi:10.1002/ptr.8184 · Cited by 23
AKOSMAN, M. S., Türkmen, R., & Demirel, H. H. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-15664-x · Cited by 23
Kamal, K. Y., & Trombetta-Lima, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062802 · Cited by 25
Potential of resveratrol in the treatment of interstitial lung disease
Huo, R., Huang, X., Yang, Y., Yang, Y., & Lin, J.-Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1139460 · Cited by 23
Phukan, B. C., Roy, R., Gahatraj, I., Bhattacharya, P., & Borah, A. (2023) · Phytotherapy Research · doi:10.1002/ptr.8012 · Cited by 22
Mohammadi, S., Moghadam, M. D., Nasiriasl, M., Akhzari, M., & Barazesh, M. (2024) · Current Clinical Pharmacology · doi:10.2174/0127724328268507231218051058 · Cited by 22
Renal Fibrosis: SIRT1 Still of Value
Wu, H., Qiu, Z., Wang, L., & Li, W. (2024) · Biomedicines · doi:10.3390/biomedicines12091942 · Cited by 21
Cavalieri, E. L., & Rogan, E. G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158238 · Cited by 21
Mitra, S., Patra, T., Saha, D., Ghosh, P., Mustafi, S. M., Varghese, A. C., & Murmu, N. (2022) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23058 · Cited by 21
Tondt, J., & Bays, H. E. (2022) · Obesity Pillars · doi:10.1016/j.obpill.2022.100017 · Cited by 22
Mesmar, J. E., Abdallah, R., Hamade, K., Baydoun, S. E., Al‐Thani, N. A., Shaito, A. A., Maresca, M., Badran, A., & Baydoun, E. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.994025 · Cited by 25
Self-citationIntracellular Redox Behavior of Quercetin and Resveratrol Singly and in Mixtures
Giordano, M. E., & Lionetto, M. G. (2023) · Molecules · doi:10.3390/molecules28124682 · Cited by 22
Pourhajibagher, M., Bahrami, R., Bazarjani, F., & Bahador, A. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103669 · Cited by 21
Recent advances in the use of resveratrol against Staphylococcus aureus infections (Review)
Cui, W., Wang, Y., Zhang, L., Liu, F., Duan, G., Chen, S., Long, J., Jin, Y., & Yang, H. (2024) · Medicine International · doi:10.3892/mi.2024.191 · Cited by 20
Jeayeng, S., Kwanthongdee, J., Jittreeprasert, R., Runganantchai, K., Naksavasdi, K., Rirkkrai, R., Wongcharoenthavorn, V., Mahikul, W., & Chatsirisupachai, A. (2025) · PeerJ · doi:10.7717/peerj.19316 · Cited by 22
Civelek, M., Bilotta, S., & Lorentz, A. (2022) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200170 · Cited by 20
Dagar, N., Kale, A., Jadhav, H. R., & Gaikwad, A. B. (2023) · Fitoterapia · doi:10.1016/j.fitote.2023.105563 · Cited by 20
Resveratrol against Cardiac Fibrosis: Research Progress in Experimental Animal Models
Yu, D., Tang, Z., Li, B., Yu, J., Li, W., Liu, Z., & Tian, C. (2021) · Molecules · doi:10.3390/molecules26226860 · Cited by 23
Liao, H., Huang, J., Liu, J., Chen, Y., Zhu, H., Li, X., Wen, J., Xiang, Q., & Yang, Q. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13020268 · Cited by 19
Zhang, X., Li, Y., Wu, Z., Li, J., Li, J., Deng, S., & Liu, G. (2023) · Food & Function · doi:10.1039/d2fo03180a · Cited by 19
Yang, M., Shen, Y., Zhao, S., Zhang, R., Dong, W., & Lei, X. (2023) · BMC Neuroscience · doi:10.1186/s12868-023-00797-1 · Cited by 19
Plant-Derived Nutraceuticals Involved in Body Weight Control by Modulating Gene Expression
Vrânceanu, M., Hegheş, S. C., Cozma-Petruț, A. P., Banc, R., Stroia, C. M., Raischi, V., Miere, D., Popa, D., & Filip, L. A. (2023) · Plants · doi:10.3390/plants12122273 · Cited by 22
Shintani, T., Shintani, H., Sato, M., & Ashida, H. (2023) · GeroScience · doi:10.1007/s11357-023-00851-0 · Cited by 19
Non-alcoholic fatty liver disease: Dietary and nutraceutical approaches
Cogorno, L., Formisano, E., Vignati, A., Prigione, A., Tramacere, A., Borgarelli, C., Sukkar, S. G., & Pisciotta, L. (2023) · Liver Research · doi:10.1016/j.livres.2023.08.005 · Cited by 19
Wang, B., Jiang, H., Qi, L., Li, X., Huang, Q., Xie, X., & Xia, Q. (2023) · Phytotherapy Research · doi:10.1002/ptr.8021 · Cited by 19
Xiong, Y., Tao, K., Li, T., Ou, W., Zhou, Y., Zhang, W., Wang, S., Qi, R., & Ji, J. (2024) · Food & Function · doi:10.1039/d3fo05131e · Cited by 19
Yadav, V., Mythri, C., & Kumarasamy, M. (2024) · Brain Behavior and Immunity Integrative · doi:10.1016/j.bbii.2024.100048 · Cited by 22
Role of cellular senescence in hepatic diseases (Review)
Xing, Y., & Zhu, J. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5623 · Cited by 19
Deng, X., Zhang, H., Chen, W., & Wang, Y. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02520-5 · Cited by 18
The Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis
Lipert, A., Szadkowska, I., Matusiak‐Wieczorek, E., & Kochan, E. (2022) · Antioxidants · doi:10.3390/antiox11081419 · Cited by 21
Ramli, I., Posadino, A. M., Zerizer, S., Spissu, Y., Barberis, A., Djeghim, H., Azara, E., Bensouıcı, C., Kabouche, Z., Rebbas, K., et al. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115722 · Cited by 18
Self-citationValookaran, A. F., Bouchard, J., Aloud, B. M., Thandapilly, S. J., & Netticadan, T. (2022) · Molecules · doi:10.3390/molecules27217222 · Cited by 21
Nanophytomedicine: A promising practical approach in phytotherapy
Sardarabadi, H., Darvishi, M. H., Zohrab, F., & Javadi, H. (2024) · Phytotherapy Research · doi:10.1002/ptr.8230 · Cited by 19
Zhao, W., Zhu, Y., Wong, S. K., Muhammad, N., Pang, K.-L., & Chin, K. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e34064 · Cited by 17
Wine, Polyphenols, and the Matrix Effect: Is Alcohol Always the Same?
Miraldi, E., Baini, G., Biagi, M., Cappellucci, G., Giordano, A., Vaccaro, F., & Bertelli, A. A. E. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189796 · Cited by 17
Montoya-Estrada, A., García-Cortés, A. Y., Romo‐Yáñez, J., Ortíz-Luna, G. F., Arellano‐Eguiluz, A., Belmont-Gómez, A., López-Ugalde, León‐Reyes, G., Pliego, A. F., Espejel-Núñez, A., et al. (2024) · Nutrients · doi:10.3390/nu16213775 · Cited by 17
Long, J., Lai, H.-Z., Huang, Y. Q., You, F., Jiang, Y., & Kuang, Q.-X. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107589 · Cited by 17
Domi, E., & Hoxha, M. (2025) · Nutrients · doi:10.3390/nu17213316 · Cited by 20
Rok, J., Rzepka, Z., Maszczyk, M., Beberok, A., & Wrześniok, D. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041642 · Cited by 16
Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells
AlKahlout, A., Fardoun, M., Mesmar, J. E., Abdallah, R., Badran, A., Nasser, S. A., Baydoun, S. E., Kobeissy, F. H., Shaito, A. A., Iratni, R., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.922196 · Cited by 18
Self-citationResveratrol as a potential protective compound against skeletal muscle insulin resistance
Bahramzadeh, A., Bolandnazar, K., & Meshkani, R. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e21305 · Cited by 17
Yang, X., Ding, W., Chen, Z., Lai, K., & Liu, Y. (2024) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3762 · Cited by 18
Anti-tumor Effects of Polyphenols via Targeting Cancer Driving Signaling Pathways: A Review
Moar, K., Yadav, S., Pant, A., Deepika, & Maurya, P. K. (2024) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-024-01222-y · Cited by 17
Ji, Q., Zhang, F., Zhang, Y., Su, Q., He, T., Hou, S., & Gui, L. (2024) · Antioxidants · doi:10.3390/antiox13080892 · Cited by 17
Background to the ANDRILL McMurdo Ice Shelf Project (Antarctica) and Initial Science Volume
Naish, T., Powell, R. D., & Levy, R. (2007) · Lincoln (University of Nebraska) · Cited by 17
Miller, S. J., Darji, R. Y., Walaieh, S., Lewis, J. A., & Logan, R. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1271941 · Cited by 16
Xu, M., Feng, P., Yan, J., & Li, L. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1474310 · Cited by 19
Plant-Based Inhibitors of Protein Aggregation
Zhytniakivska, O. A., Chaturvedi, T., & Thomsen, M. H. (2025) · Biomolecules · doi:10.3390/biom15040481 · Cited by 18
Yin, W., Yang, Y., Yue, Z., Wang, R., Bai, L., Lin, Y., Chen, X., & Cai, X. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123780 · Cited by 17
Totonchi, H., Mokarram, P., Karima, S., Rezaei, R., Dastghaib, S., Koohpeyma, F., Noori, S., & Azarpira, N. (2022) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-022-00611-4 · Cited by 16
The Effects of Resveratrol Supplementation on the Metabolism of Lipids in Metabolic Disorders
Ghavidel, F., Hashemy, S. I., Aliari, M., Rajabian, A., Tabrizi, M. H., Atkin, S. L., Jamialahmadi, T., Hosseini, H., & Sahebkar, A. (2023) · Current Medicinal Chemistry · doi:10.2174/0109298673255218231005062112 · Cited by 15
Abdallah, R., Shaito, A. A., Badran, A., Baydoun, S. E., Sobeh, M., Ouchari, W., Sahri, N., Eid, A. H., Mesmar, J. E., & Baydoun, E. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1331843 · Cited by 20
Self-citationFerreira, F. R., Moura, N., Hassib, L., & Pombo, T. R. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135100 · Cited by 16
Aleynova, O. A., Suprun, A. R., Ananev, A. A., Nityagovsky, N. N., Ogneva, Z. V., Dubrovina, A. S., & Kiselev, K. V. (2022) · Plants · doi:10.3390/plants11020171 · Cited by 15
Plant Materials for the Production of Functional Foods for Weight Management and Obesity Prevention
Stabnikova, О., & Paredes‐López, O. (2023) · Current Nutrition & Food Science · doi:10.2174/1573401319666230705110854 · Cited by 46
Current Small Molecule–Based Medicinal Chemistry Approaches for Neurodegeneration Therapeutics
Sanghai, N., Vuong, B., Berk, A. B., Afridi, M. S. K., & Tranmer, G. K. (2024) · ChemMedChem · doi:10.1002/cmdc.202300705 · Cited by 15
Naskar, R., Ghosh, A., Bhattacharya, R., & Chakraborty, S. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105859 · Cited by 16
Nutraceutical tablets: Manufacturing processes, quality assurance, and effects on human health
Manzoor, M. F., Riaz, S., Verma, D. K., Waseem, M., Gökşen, G., Ali, A., & Zeng, X. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115197 · Cited by 15
Exercise, exerkines and exercise mimetic drugs: Molecular mechanisms and therapeutics
Samant, V., & Prabhu, A. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.123225 · Cited by 15
Sirtuin 1 and Hormonal Regulations in Aging
Keremidarska‐Markova, M., Sazdova, I., Mladenov, M. I., Pilicheva, B., Zagorchev, P. I., & Gagov, H. (2024) · Applied Sciences · doi:10.3390/app142412051 · Cited by 18
Ciobârcă, D., Cătoi, A. F., Gavrilaș, L., Banc, R., Miere, D., & Filip, L. A. (2025) · Pharmaceuticals · doi:10.3390/ph18020279 · Cited by 18
Natural Dibenzo-α-Pyrones: Friends or Foes?
Aichinger, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222313063 · Cited by 16
Storgaard, J. H., Løkken, N., Madsen, K. L., Voermans, N. C., Laforêt, P., Nadaj‐Pakleza, A., Tard, C., van Hall, G., Vissing, J., & Ørngreen, M. C. (2022) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12479 · Cited by 15
Establishment of Dosage of Bioactive Compounds in Functional Food Products
Martirosyan, D. M., & Sanchez, S. S. (2022) · Functional Food Science · doi:10.31989/ffs.v2i3.915 · Cited by 15
Roumes, H., Goudeneche, P., Pellerin, L., & Bouzier‐Sore, A. (2022) · Nutrients · doi:10.3390/nu14183793 · Cited by 15
Jang, B.-G., Lee, J., Choi, B., Koh, Y. H., & Kim, M.-J. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112185 · Cited by 15
Wakamatsu, K., & Ito, S. (2021) · Springer eBooks · doi:10.1007/978-981-16-1490-3_2 · Cited by 14
Mukherjee, M., Rahaman, M., Ray, S. K., Shukla, P. C., Dolai, T. K., & Chakravorty, N. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06977-8 · Cited by 20
Cai, W., Li, Z., Wang, W., Liu, S., Li, Y., Sun, X., Sutton, R., Deng, L., Liu, T., Xia, Q., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156538 · Cited by 15
Impact of gut microbiota in chronic kidney disease: natural polyphenols as beneficial regulators
Cheng, L., Chen, X., Zha, W., Fang, S., Shen, J., Li, L., Jiang, H., & Tian, P. (2025) · Renal Failure · doi:10.1080/0886022x.2025.2506810 · Cited by 17
Ghosh, S., Debnath, I., Bhunia, S., Nandi, S., Ashique, S., Nayak, A., Mallick, S., & Basak, S. (2025) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2025.09.005 · Cited by 16
Dietary polyphenols as modulators of cell signaling and inflammation in colorectal carcinogenesis
Tan, B. L., Zulkifli, F., & Norhaizan, M. E. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1691590 · Cited by 14
Hormesis-Mediated Mechanisms Underlying Bioactivities of Phytochemicals
Murakami, A. (2020) · Current Pharmacology Reports · doi:10.1007/s40495-020-00235-4 · Cited by 15
Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats
Simões, M., Ames-Sibin, A. P., de Lima, E. P., Pateis, V. D. O., Bersani‐Amado, C. A., Mathias, P. C. D. F., Peralta, R. M., de Sá‐Nakanishi, A. B., Bracht, L., Bracht, A., et al. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120991 · Cited by 14
Effects of lifespan-extending interventions on cognitive healthspan
Čulig, L., Sahbaz, B. D., & Bohr, V. A. (2022) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.36 · Cited by 14
Kamenova, K., Radeva, L., Konstantinov, S., Petrov, P. D., & Yoncheva, K. (2023) · Polymers · doi:10.3390/polym15183769 · Cited by 14
Chen, B., Dong, X., Zhang, J., Wang, W., Song, Y., Sun, X., Zhao, K., & Sun, Z. (2023) · Medicine · doi:10.1097/md.0000000000036157 · Cited by 16
Wongrakpanich, A., Thu, H. B. T., Sakchaisri, K., Taresco, V., Crucitti, V. C., Bunsupa, S., & Suksiriworapong, J. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105610 · Cited by 14
The Role of Natural Products from Herbal Medicine in TLR4 Signaling for Colorectal Cancer Treatment
Luo, Y., Zhang, G., Hu, C., Huang, L., Wang, D., Chen, Z., & Wang, Y. (2024) · Molecules · doi:10.3390/molecules29122727 · Cited by 14
Effects of Resveratrol on Nonmelanoma Skin Cancer ( NMSC ): A Comprehensive Review
Zamanian, M. Y., Shahbazi, T., Kazmi, S. W., Hussien, B. M., Sharma, A., Qasim, M. T., Hjazi, A. M., Sapaev, I. B., Danesh, A. N., Taheri, N., et al. (2024) · Food Science & Nutrition · doi:10.1002/fsn3.4555 · Cited by 16
The Quest for Eternal Youth: Hallmarks of Aging and Rejuvenating Therapeutic Strategies
Nunkoo, V. S., Cristian, A., Jurcău, A., Diaconu, R. G., & Jurcău, M. C. (2024) · Biomedicines · doi:10.3390/biomedicines12112540 · Cited by 15
Resveratrol induces H3 and H4K16 deacetylation and H2A.X phosphorylation in Toxoplasma gondii
Contreras, M., Ganuza, A., Corvi, M. M., & Angel, S. O. (2021) · BMC Research Notes · doi:10.1186/s13104-020-05416-4 · Cited by 14
Are Nutraceuticals Beneficial in Chronic Kidney Disease?
Rysz, J., Franczyk, B., Kujawski, K., Sacewicz‐Hofman, I., Ciałkowska-Rysz, A. D., & Gluba-Brzózka, A. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13020231 · Cited by 14
Molecular encapsulation and bioactivity of gnetol, a resveratrol analogue, for use in foods
Navarro‐Orcajada, S., Conesa, I., Matencio, A., García‐Carmona, F., & López-Nicolás, M. (2022) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.11781 · Cited by 14
Karthika, C., Najda, A., Klepacka, J., Zehravi, M., Akter, R., Akhtar, M. F., Saleem, A., Al‐Shaeri, M., Mondal, B., Ashraf, G. M., et al. (2022) · Molecules · doi:10.3390/molecules27144663 · Cited by 14
The effect of Resveratrol on the pharmacokinetic profile of tofacitinib and the underlying mechanism
Ye, Z., Hu, J., Wang, J., Liu, Y.-N., Xu, R.-A., & Xu, R.-A. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110398 · Cited by 14
Gaggini, M., Fenizia, S., & Vassalle, C. (2023) · Antioxidants · doi:10.3390/antiox12051102 · Cited by 16
Giri, P., Camarillo, I. G., & Sundararajan, R. (2023) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2023.00122 · Cited by 13
Lacruz-Pleguezuelos, B., Piette, O., Garranzo, M., Pérez-Serrano, D., Milešević, J. P., Espinosa‐Salinas, I., de Molina, A. R., Laguna, T., & Pau, E. C. D. S. (2023) · Database · doi:10.1093/database/baad075 · Cited by 13
Akbel, E., Küçükkurt, İ., İnce, S., Demirel, H. H., Arslan‐Acaröz, D., Zemheri‐Navruz, F., & Kan, F. (2023) · Toxicology Research · doi:10.1093/toxres/tfad123 · Cited by 15
Li, F., Lin, H., Qin, X., Gao, J., Chen, Z., Cao, W., Zheng, H., & Xie, S. (2024) · Marine Drugs · doi:10.3390/md22080359 · Cited by 16
Radeva, L., Yordanov, Y., Spassova, I., Kovacheva, D., Tzankova, V., & Yoncheva, K. (2024) · Gels · doi:10.3390/gels10110699 · Cited by 13
Qin, X., Niu, W., Zhao, K., Luo, Y., Wang, W., He, Y., Yang, F., Cao, B., Du, ., & Su, H. (2025) · Current Research in Food Science · doi:10.1016/j.crfs.2025.100972 · Cited by 16
Metadata
- Authors
- Shaito, A., Posadino, A. M., Younes, N., Hasan, H., Halabi, S., Alhababi, D., Al-Mohannadi, A., Abdel-Rahman, W. M., Eid, A. H., Nasrallah, G. K., & Pintus, G.
- Affiliations
- Lebanese International University (LB)
- University of Sassari (IT)
- Qatar University (QA)
- Justus-Liebig-Universität Gießen (DE)
- American University of Beirut (LB)
- Department of Medical Laboratory Sciences, College of Health Sciences and Sharjah Institute for Medical Research, University of Sharjah, Sharjah P.O Box: 27272, United Arab Emirates
- Corresponding author
- Eid, Ali H.
- Nasrallah, Gheyath K.
- Pintus, Gianfranco
- ORCID
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-03-18
- Volume
- 21
- Issue
- 6
- Pages
- 2084
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC7139620
- OpenAlex
- W3011177534
- Cited by
- 716
- References
- 226
- Citations by year
- 2026: 104 · 2025: 147 · 2024: 125 · 2023: 116 · 2022: 107 · 2021: 83 · 2020: 31
- FWCI
- 10.47
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UnissResearch (Università degli Studi di Sassari) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Qatar University QSpace (Qatar University) (submittedVersion)
- Funders
- Qatar University (IRCC#181)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Sirtuins and Resveratrol in Medicine
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- resveratrol, toxicity, adverse effects, stilbenoids, natural polyphenols, bioavailability, drug interactions, dosage, French paradox, cardioprotection, neuroprotection, anti-inflammatory activity, antioxidant activity, anticancer effects, anti-diabetic effects, anti-aging effects, delivery methods
- MeSH terms
- Resveratrol, Humans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
